Intracellular localization of 3-substituted aryl oxindole (PH II-7)

Chinese Pharmacological Bulletin

Volumn 25, Issue 6, 2009, Pages

  Zhou, Yuan ^a   Wang, Cai Yun ^a   Su, Ye ^a   Cheng, Xin ^a   Peng, Hong Wei ^a   Yang, Chun Zheng ^a   Xiong, Dong Sheng ^a  

^a INSTITUTE OF HEMATOLOGY AND BLOOD DISEASES HOSPITAL   (China)

Author keywords

Confocal scanning laser microscope; Intracellular localization; Multidrug resistance; Oxindoles

Indexed keywords

ANTINEOPLASTIC AGENT; ARYLOXINDOLE; DOXORUBICIN; FLUORESCEIN ISOTHIOCYANATE; PH II 7; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL; ORGANIC CHEMISTRY;

EID: 68849122490     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Tan Y H, Qi J, Liu W J, et al. Preliminary studies on the mechanism of a new anti-tumor agent PH II-7 with special preference to multidrug resistance tumor cells[J]. Acta Acad Med Sin, 2002,24(2):134-139
2. Messaoudi S, Sancelme M, Polard-Housset V, et al. Synthesis and biological evaluation of oxindoles and benzimidazolinones derivatives[J]. Eur J Med Chem, 2004,39(5):453-458 (Pubitemid 38526362)
3. Ortiz Barbosa Y A, Hart D J, Magomedov N A. Spiroquinazoline support studies: methods for the preparation of imidazoloindolines from oxindoles[J]. Tetrahedron, 2006,62(37):8748-8754
4. De Almeida M V, Le Hyaric M, Siqueira L J A, et al. Synthesis of furan derivatives condensed with carbohydrates [J]. Molecules, 2001,6(9):728-735 (Pubitemid 38990282)
5. Carmixhael J, DeGraff W G, Gazadar A F, et al. Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing[J]. Cancer Res, 1987,47(4):936-942 (Pubitemid 17027905)
6. Starch W B, Ruan Y B. Immunfluoreszenzfibel[M]. Beijing: People's Medical Publishing House,2000:9-15.
7. Wang L, Ke H, Wang Y Y, et al. Changes of the distribution and accumulation of adriamycin in the sensitive and multidrug-resistant HL-60 cells[J]. Chin Pharmacol Bull, 2007,23(12):1650-1653
8. Tan Y H, Yang C Z, Qi J, et al. Effects of 3-substituted aryl oxindole (PH II-7) on cell cycle of tumor cells[J]. Acta Pharm Sin, 2003,38(11):805-808