Effect of loading on the organization of the collagen fibril network in juvenile equine articular cartilage

Journal of Orthopaedic Research

Volumn 27, Issue 9, 2009, Pages 1226-1234

  Brama, Pieter A J ^a   Holopainen, Jaakko ^b   Van Weeren, P René ^c   Firth, Elwyn C ^d   Helminen, Heikki J ^b   Hyttinen, Mika M ^b  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c UTRECHT UNIVERSITY   (Netherlands)

^d MASSEY UNIVERSITY   (New Zealand)

Author keywords

Cartilage; Collagen fibril; Loading; Orientation; Parallelism

Indexed keywords

COLLAGEN FIBRIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CONTROLLED STUDY; EXERCISE; FORCE; HORSE; NONHUMAN; PRIORITY JOURNAL; WEIGHT BEARING;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; CARTILAGE, ARTICULAR; COLLAGEN; EXTRACELLULAR MATRIX; FEMALE; FORELIMB; HORSE DISEASES; HORSES; MALE; MICROSCOPY, POLARIZATION; PHYSICAL CONDITIONING, ANIMAL; WEIGHT-BEARING;

EID: 68849121451     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20866     Document Type: Article

References (31)

1. Palmer J, Bertone A. 1996. Joint biomechanics in the pathogenesis of traumatic arthritis. In: McIlwraith CW, Trotter GW, editors. Joint disease in the horse, 1st ed. Philadelphia: Saunders. p 104-119.
2. Palmer JL, Bertone AL, Malemud CJ, et al. 1995. Site-specific proteoglycan characteristics of third carpal articular cartilage in exercised and non-exercised horses. Am J Vet Res 56:1570-1576.
3. Brama PA, Tekoppele JM, Bank RA, et al. 2000. Topographical mapping of biochemical properties of articular cartilage in the equine fetlock joint. Equine Vet J 32:19-26.
4. Brama PA, Karssenberg D, Barneveld A, et al. 2001. Contact areas and pressure distribution on the proximal articular surface of the proximal phalanx under sagittal plane loading. Equine Vet J 33:26-32.
5. Brama PA, TeKoppele JM, Bank RA, et al. 1999. Influence of site and age on biochemical characteristics of the collagen network of equine articular cartilage. Am J Vet Res 60:341-345.
6. Pool RR. 1996. Pathologic manifestations of joint disease in the athletic horse. In: McIlwraith CW, Trotter GW, editors. Joint disease in the horse, 1st ed. Philadelphia: Saunders. p 87-103.
7. Benninghoff A. 1925. Form und Bau der Gelenkknorpel in ihren Beziehungen zur Funktion. Zweiter teil: Der Aufnau des Gelenkknorpels in seinen Beziehungen zur Funktion. Z Zelforsch Mikroskop Anat 2:783-862.
8. Brama PA, Tekoppele JM, Bank RA, et al. 2000. Functional adaptation of equine articular cartilage: the formation of regional biochemical characteristics up to age one year. Equine Vet J 32:217-221.
9. Brommer H, Brama PAJ, Laasanen MS, et al. 2005. Functional adaptation of articular cartilage from birth to maturity under the influence of loading: a biomechanical analysis. Equine Vet J 37:148-154.
10. Hyttinen MM, Arokoski JPA, Parkkinen JJ, et al. 2001. Age matters: collagen birefringence of superficial articular cartilage is increased in young guinea-pigs but decreased in older animals after identical physiological type of joint loading. Osteoarthritis Cartilage 9:694-701.
11. Turnhout MCV, Haazelager MB, Gijsen MA, et al. 2008. Quantitative description of collagen structure in the articular cartilage of the young and adult equine distal metacarpus. Animal Biol 58:353-370.
12. Brama PA, TeKoppele JM, Bank RA, et al. 2002. Development of biochemical heterogeneity of articular cartilage: influences of age and exercise. Equine Vet J 34:265-269.
13. Helminen HJ, Hyttinen MM, Lammi MJ, et al. 2000. Regular joint loading in youth assists in the establishment and strengthening of the collagen network of articular cartilage and contributes to the prevention of osteoarthrosis later in life: a hypothesis. J Bone Miner Metab 18:245-257.
14. Rieppo J, Hallikainen J, Jurvelin JS, et al. 2008. Practical considerations in the use of polarized light microscopy in the analysis of the collagen network in articular cartilage. Microsc Res Technol 71:279-287.
15. Rogers CW, Firth EC, McIlwraith CW, et al. 2008. Evaluation of a new strategy to modulate skeletal development in thoroughbred performance horses by imposing track-based exercise during growth. Equine Vet J 40:111-118.
16. Barneveld A, van Weeren PR. 1999. Conclusions regarding the influence of exercise on the development of the equine musculoskeletal system with special reference to osteochondrosis. Equine Vet J (Suppl 31):112-119.
17. Kiraly K, Hyttinen MM, Lapvetelainen T, et al. 1997. Specimen preparation and quantification of collagen birefringence in unstained sections of articular cartilage using image analysis and polarizing light microscopy. Histochem J 29:317-327.
18. Clark JM. 1991. Variation of collagen fiber alignment in a joint surface: a scanning electron microscope study of the tibial plateau in dog, rabbit, and man. J Orthop Res 9:246-257.
19. Modis L. 1991. Organization of the extracellular matrix: a polarization microscopic approach. Boca Raton, FL: CRC.
20. Bennet H. 1950. Methods applicable to the study of both fresh and fixed materials. The microscopical investigation of biological materials with polarized light. New York: Paul B. Hoeber. p 591-677.
21. Grunder W, Kanowski M, Wagner M, et al. 2000. Visualization of pressure distribution within loaded joint cartilage by application of angle-sensitive NMR microscopy. Magn Reson Med 43:884-891.
22. Rieppo J, Hyttinen MM, Halmesmaki E, et al. 2009. Changes in spatial collagen content and collagen network architecture in porcine articular cartilage during growth and maturation. Osteoarthritis Cartilage (in press).
23. Arokoski JPA, Hyttinen MM, Lapvetalainen T, et al. 1996. Decreased birefringence of the superficial zone collagen network in the canine knee (stifle) articular cartilage after long distance running training, detected by quantitative polarised light microscopy. Ann Rheum Dis 55:253-264.
24. Hwang WS, Li B, Jin LH, et al. 1992. Collagen fibril structure of normal, aging, and osteoarthritic cartilage. J Pathol 167:425-433.
25. Clark JM, Norman A, Notzli H. 1997. Postnatal development of the collagen matrix in rabbit tibial plateau articular cartilage. J Anat 191:215-227.
26. van Weeren PR, Firth EC, Brommer B, et al. 2008. Early exercise advances the maturation of glycosaminoglycans and collagen in the extracellular matrix of articular cartilage in the horse. Equine Vet J 40:128-135.
27. Kurvers CMHC, van Weeren PR, Rogers CW, et al. 2006. Quantification of spontaneous locomotion activity in foals kept in pastures under various management conditions. Am J Vet Res 67:1212-1217.
28. Korhonen RK, Wong M, Arokoski J, et al. 2002. Importance of the superficial tissue layer for the indentation stiffness of articular cartilage. Med Eng Phys 24:99-108.
29. Korhonen RK, Laasanen MS, Toyras J, et al. 2003. Fibril reinforced poroelastic model predicts specifically mechanical behavior of normal, proteoglycan depleted and collagen degraded articular cartilage. J Biomech 36:1373-1379.
30. Firth EC. 2006. The response of bone, articular cartilage and tendon to exercise in the horse. J Anat 208:513-526.
31. MacKelvie KJ, McKay HA, Khan KM, et al. 2001. A school-based exercise intervention augments bone mineral accrual in early pubertal girls. J Pediatr 139:501-508.