Fatal interstitial lung disease after erlotinib administration in a patient with radiation fibrosis

Clinical Respiratory Journal

Volumn 3, Issue 3, 2009, Pages 181-184

  Um, Soo Jung ^a   Lee, Soo Keol ^a   Yang, Doo Kyung ^a   Son, Choonhee ^a   Roh, Mee Sook ^a   Kim, Ki Nam ^a   Lee, Ki Nam ^a   Choi, Pil Jo ^a  

^a Dong A University   (South Korea)

Author keywords

Erlotinib; Interstitial lung disease; Non small cell lung cancer; Radiation fibrosis

Indexed keywords

AMITRIPTYLINE; C REACTIVE PROTEIN; CISPLATIN; DOCETAXEL; ERLOTINIB; FENTANYL; GABAPENTIN; LEVOFLOXACIN; MEROPENEM; METHYLPREDNISOLONE; OXYCODONE; PEMETREXED;

ADULT; ARTICLE; BACTERIAL PNEUMONIA; CANCER COMBINATION CHEMOTHERAPY; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DISEASE COURSE; DRUG FATALITY; DRUG WITHDRAWAL; DYSPNEA; FIBROSIS; HUMAN; INTERSTITIAL LUNG DISEASE; LEUKOCYTOSIS; LUNG NON SMALL CELL CANCER; MALE; MORTALITY; MULTIPLE CYCLE TREATMENT; PRIORITY JOURNAL; RADIATION DOSE; RADIATION FIBROSIS; RADIATION INJURY; RESPIRATORY FAILURE; THORAX RADIOGRAPHY;

CARCINOMA, NON-SMALL-CELL LUNG; COMBINED MODALITY THERAPY; FATAL OUTCOME; HUMANS; LUNG DISEASES, INTERSTITIAL; LUNG NEOPLASMS; MALE; MIDDLE AGED; PROTEIN KINASE INHIBITORS; QUINAZOLINES; RADIATION PNEUMONITIS;

EID: 68849119629     PISSN: 17526981     EISSN: 1752699X     Source Type: Journal    
DOI: 10.1111/j.1752-699X.2008.00115.x     Document Type: Article

References (14)

1. Shepherd FA, Pereira JR, Ciuleanu T, et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med. 2005 353 : 123 32. (Pubitemid 41058344)
2. Tammaro KA, Baldwin PD, Lundberg AS. Interstitial lung disease following erlotinib (Tarceva) in a patient who previously tolerated gefitinib (Iressa). J Oncol Pharm Pract. 2005 11 : 127 30.
3. Makris D, Scherpereel A, Copin MC, Colin G, Brun L, Lafitte JJ, Marquette CH. Fatal interstitial lung disease associated with oral erlotinib therapy for lung cancer. BMC Cancer. 2007 7 : 150 3.
4. Inoue A, Saijo Y, Maemondo M, Gomi K, Tokue Y, Kimura Y, Ebina M, Kikuchi T, Moriya T, Nukiwa T. Severe acute interstitial pneumonia and gefitinib. Lancet. 2003 361 : 137 9.
5. Seto T, Seki N, Uematsu K, Tanigaki T, Shioya S, Koboyashi T, Umemura S, Eguchi K. Gefitinib-induced lung injury successfully treated with high-dose corticosteroids. Respirology. 2006 11 : 113 6.
6. Ando M, Okamoto I, Yamamoto N, Takeda K, Tamura K, Seto T, Ariyoshi Y, Fukuoka M. Predictive factors for interstitial lung disease, antitumor response, and survival in non-small-cell lung cancer patients treated with gefitinib. J Clin Oncol. 2006 24 : 2549 56.
7. Liu V, White DA, Zakowski MF, Travis W, Kris MG, Ginsberg MS, Miller VA, Azzoli CG. Pulmonary toxicity associated with erlotinib. Chest. 2007 132 : 1042 4.
8. Suzuki H, Aoshiba K, Yokohori N, Nagai A. Epidermal growth factor receptor tyrosine kinase inhibition augments a murine model of pulmonary fibrosis. Cancer Res. 2003 63 : 5054 9.
9. Wynn TA. Cellular and molecular mechanisms of fibrosis. J Pathol. 2008 214 : 199 210.
10. Martin C, Romero S, Sanchez-Paya J, Massuti B, Arriero JM, Hernadez L. Bilateral lymphocytic alveolitis: a common reaction after unilateral thoracic irradiation. Eur Respir J. 1999 13 : 727 32.
11. Frognier R, Monnot H, Levy A, Devuyst P, Cordier J-F Groupe d'Etudes et de Recherche sur les Maladies "Orphelines" Pulmonaires (GERM"O"P). Chronic eosinophilic pneumonia after radiation therapy for breast cancer. Eur Respir J. 2004 23 : 9 13.
12. Lienbaum RC. Carboplatin and paclitaxel albumin-stabilized nanoparticle formulation followed by radiation therapy and erlotinib in treating patients with stage III non-small cell lung cancer that cannot be removed by surgery. Available from URL: http:// clinicaltrials.gov/ct2/show/NCT00553452 [accessed 31 October 2008].
13. T, Ossorio MA, Cipolla LM, Fields CL, Snider HL, Anderson WH. Pulmonary complications after tricyclic antidepressant overdose. Chest. 1989 96 : 852 6.
14. Noh H, Lee YK, Kang SW, Choi KH, Han DS, Lee HY. Acute eosinophilic pneumonia associated with amitriptyrine in a hemodialysis patient. Yonsei Med J. 2001 42 : 357 9.