Over-expression of pancreatic pituitary adenylate cyclase-activating polypeptide (PACAP) aggravates cerulein-induced acute pancreatitis in mice

Journal of Pharmacological Sciences

Volumn 110, Issue 4, 2009, Pages 451-458

  Hamagami, Ken Ichi ^a   Sakurai, Yusuke ^a   Shintani, Norihito ^a   Higuchi, Naoko ^a   Ikeda, Kazuya ^a   Hashimoto, Hitoshi ^a,b   Suzuki, Akinobu ^c   Kiyama, Hiroshi ^c   Baba, Akemichi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Acute pancreatitis; Cerulein; Pituitary adenylate cyclase activating polypeptide (PACAP); Regenerating gene III (RegIII )

Indexed keywords

AMYLASE; ANTIINFLAMMATORY AGENT; CERULETIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; REGENERATING GENE III BETA; TRIACYLGLYCEROL LIPASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACINAR CELL; ACUTE PANCREATITIS; AMYLASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE EXACERBATION; EDEMA; INFLAMMATION; MOUSE; NECROSIS; NONHUMAN; PANCREAS CELL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; TRIACYLGLYCEROL LIPASE BLOOD LEVEL; UPREGULATION; WILD TYPE;

ACUTE DISEASE; AMYLASES; ANIMALS; CAERULEIN; CYTOKINES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; INSULIN-SECRETING CELLS; LIPASE; MICE; MICE, TRANSGENIC; PANCREATITIS; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; PROTEINS; RNA, MESSENGER; UP-REGULATION;

EID: 68849118474     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.09119FP     Document Type: Article

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