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Volumn 22, Issue 4, 2009, Pages 368-377

Week-long high-maintenance dose clopidogrel regimen achieves better platelet aggregation inhibition than a standard loading dose before percutaneous coronary intervention: Results of a double-blind, randomized clinical trial

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NITRIC ACID DERIVATIVE; PROTON PUMP INHIBITOR; ANTITHROMBOCYTIC AGENT; TICLOPIDINE;

EID: 68849091527     PISSN: 08964327     EISSN: 15408183     Source Type: Journal    
DOI: 10.1111/j.1540-8183.2009.00486.x     Document Type: Article
Times cited : (8)

References (39)
  • 1
    • 0030027222 scopus 로고    scopus 로고
    • Subacute stent thrombosis: Evolving issues and current concepts
    • Mak KH, Belli G, Ellis SG, et al. Subacute stent thrombosis: Evolving issues and current concepts. J Am Coll Cardiol 1996 27 : 494 503.
    • (1996) J Am Coll Cardiol , vol.27 , pp. 494-503
    • Mak, K.H.1    Belli, G.2    Ellis, S.G.3
  • 2
    • 0029838529 scopus 로고    scopus 로고
    • Antiplatelet therapy
    • Schafer AI. Antiplatelet therapy. Am J Med 1996 101 : 199 209.
    • (1996) Am J Med , vol.101 , pp. 199-209
    • Schafer, A.I.1
  • 3
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • The clopidogrel in unstable angina to prevent recurrent events trial investigators
    • The clopidogrel in unstable angina to prevent recurrent events trial investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001 345 : 494 502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
  • 4
    • 0037145863 scopus 로고    scopus 로고
    • Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: A randomized controlled trial
    • Steinhubl SR, Berger PB, Mann JT, III., et al. Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: A randomized controlled trial. JAMA 2002 288 : 2411 2420.
    • (2002) JAMA , vol.288 , pp. 2411-2420
    • Steinhubl, S.R.1    Berger, P.B.2    Mann Iii, J.T.3
  • 5
    • 17144370263 scopus 로고    scopus 로고
    • Resistance to clopidogrel: A review of the evidence
    • Nguyen TA, Diodati JG, Pharand C. Resistance to clopidogrel: A review of the evidence. J Am Coll Cardiol 2005 45 : 1157 1164.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1157-1164
    • Nguyen, T.A.1    Diodati, J.G.2    Pharand, C.3
  • 6
    • 0038354521 scopus 로고    scopus 로고
    • Resistance to thienopyridines: Clinical detection of coronary stent thrombosis by monitoring of vasodilator-stimulated phosphoprotein phosphorylation
    • Barragan P, Bouvier JL, Roquebert PO, et al. Resistance to thienopyridines: Clinical detection of coronary stent thrombosis by monitoring of vasodilator-stimulated phosphoprotein phosphorylation. Catheter Cardiovasc Interv 2003 59 : 295 302.
    • (2003) Catheter Cardiovasc Interv , vol.59 , pp. 295-302
    • Barragan, P.1    Bouvier, J.L.2    Roquebert, P.O.3
  • 7
    • 8344221349 scopus 로고    scopus 로고
    • Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction
    • Matetzky S, Shenkman B, Guetta V, et al. Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction. Circulation 2004 109 : 3171 3175.
    • (2004) Circulation , vol.109 , pp. 3171-3175
    • Matetzky, S.1    Shenkman, B.2    Guetta, V.3
  • 8
    • 33749503499 scopus 로고    scopus 로고
    • Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation
    • Geisler T, Langer H, Wydymus M, et al. Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation. Eur Heart J 2006 27 : 2420 2425.
    • (2006) Eur Heart J , vol.27 , pp. 2420-2425
    • Geisler, T.1    Langer, H.2    Wydymus, M.3
  • 9
    • 33845297690 scopus 로고    scopus 로고
    • Value of platelet reactivity in predicting response to treatment and clinical outcome in patients undergoing primary coronary intervention: Insights into the STRATEGY Study
    • Campo G, Valgimigli M, Gemmati D, et al. Value of platelet reactivity in predicting response to treatment and clinical outcome in patients undergoing primary coronary intervention: Insights into the STRATEGY Study. J Am Coll Cardiol 2006 48 : 2178 2185.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 2178-2185
    • Campo, G.1    Valgimigli, M.2    Gemmati, D.3
  • 10
    • 18144371221 scopus 로고    scopus 로고
    • The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting
    • Gurbel PA, Bliden KP, Hayes KM, et al. The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting. J Am Coll Cardiol 2005 45 : 1392 1396.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1392-1396
    • Gurbel, P.A.1    Bliden, K.P.2    Hayes, K.M.3
  • 11
    • 33750479499 scopus 로고    scopus 로고
    • Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement
    • Hochholzer W, Trenk D, Bestehorn HP, et al. Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement. J Am Coll Cardiol 2006 48 : 1742 1750.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1742-1750
    • Hochholzer, W.1    Trenk, D.2    Bestehorn, H.P.3
  • 12
    • 9644281093 scopus 로고    scopus 로고
    • The difference between clopidogrel responsiveness and posttreatment platelet reactivity
    • Samara WM, Bliden KP, Tantry US, et al. The difference between clopidogrel responsiveness and posttreatment platelet reactivity. Thromb Res 2005 115 : 89 94.
    • (2005) Thromb Res , vol.115 , pp. 89-94
    • Samara, W.M.1    Bliden, K.P.2    Tantry, U.S.3
  • 13
    • 33748948717 scopus 로고    scopus 로고
    • Benefit of a 600-mg loading dose of clopidogrel on platelet reactivity and clinical outcomes in patients with non-ST-segment elevation acute coronary syndrome undergoing coronary stenting
    • Cuisset T, Frere C, Quilici J, et al. Benefit of a 600-mg loading dose of clopidogrel on platelet reactivity and clinical outcomes in patients with non-ST-segment elevation acute coronary syndrome undergoing coronary stenting. J Am Coll Cardiol 2006 48 : 1339 1345.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1339-1345
    • Cuisset, T.1    Frere, C.2    Quilici, J.3
  • 14
    • 0038649988 scopus 로고    scopus 로고
    • Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity
    • Gurbel PA, Bliden KP, Hiatt BL, et al. Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity. Circulation 2003 107 : 2908 2913.
    • (2003) Circulation , vol.107 , pp. 2908-2913
    • Gurbel, P.A.1    Bliden, K.P.2    Hiatt, B.L.3
  • 15
    • 65449158776 scopus 로고    scopus 로고
    • Clopidogrel resistance: Pharmacokinetic or pharmacogenetic?
    • Ford NF. Clopidogrel resistance: Pharmacokinetic or pharmacogenetic? J Clin Pharmacol 2009 49 : 506 512.
    • (2009) J Clin Pharmacol , vol.49 , pp. 506-512
    • Ford, N.F.1
  • 16
    • 65249184387 scopus 로고    scopus 로고
    • Effects of aspirin dose on ischaemic events and bleeding after percutaneous coronary intervention: Insights from the PCI-CURE study
    • Jolly SS, Pogue J, Haladyn K, et al. Effects of aspirin dose on ischaemic events and bleeding after percutaneous coronary intervention: Insights from the PCI-CURE study. Eur Heart J 2009 30 : 900 907.
    • (2009) Eur Heart J , vol.30 , pp. 900-907
    • Jolly, S.S.1    Pogue, J.2    Haladyn, K.3
  • 17
    • 38349076614 scopus 로고    scopus 로고
    • 2007 focused update of the ACC-AHA-SCAI 2005 guideline update for percutaneous coronary intervention: A report of the American College of Cardiology-American Heart Association Task Force on Practice guidelines
    • King SB, III., Smith SC, Jr., Hirshfeld JW, Jr., et al. 2007 focused update of the ACC-AHA-SCAI 2005 guideline update for percutaneous coronary intervention: A report of the American College of Cardiology-American Heart Association Task Force on Practice guidelines. J Am Coll Cardiol 2008 51 : 172 209.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 172-209
    • King Iii, S.B.1    Smith Jr., S.C.2    Hirshfeld Jr., J.W.3
  • 18
    • 20244377701 scopus 로고    scopus 로고
    • Guidelines for percutaneous coronary interventions. the Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology
    • Silber S, Albertsson P, Aviles FF, et al. Guidelines for percutaneous coronary interventions. The Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology. Eur Heart J 2005 26 : 804 847.
    • (2005) Eur Heart J , vol.26 , pp. 804-847
    • Silber, S.1    Albertsson, P.2    Aviles, F.F.3
  • 19
    • 0023864355 scopus 로고
    • Thrombolysis in Myocardial Infarction (TIMI) Trial-phase I: Hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase
    • Rao AK, Pratt C, Berke A, et al. Thrombolysis in Myocardial Infarction (TIMI) Trial-phase I: Hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase. J Am Coll Cardiol 1988 11 : 1 11.
    • (1988) J Am Coll Cardiol , vol.11 , pp. 1-11
    • Rao, A.K.1    Pratt, C.2    Berke, A.3
  • 20
    • 44949173754 scopus 로고    scopus 로고
    • Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation
    • Price MJ, Endemann S, Gollapudi RR, et al. Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation. Eur Heart J 2008 29 : 992 1000.
    • (2008) Eur Heart J , vol.29 , pp. 992-1000
    • Price, M.J.1    Endemann, S.2    Gollapudi, R.R.3
  • 21
    • 7544239072 scopus 로고    scopus 로고
    • High clopidogrel loading dose during coronary stenting: Effects on drug response and interindividual variability
    • Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, et al. High clopidogrel loading dose during coronary stenting: Effects on drug response and interindividual variability. Eur Heart J 2004 25 : 1903 1910.
    • (2004) Eur Heart J , vol.25 , pp. 1903-1910
    • Angiolillo, D.J.1    Fernandez-Ortiz, A.2    Bernardo, E.3
  • 22
    • 33847130538 scopus 로고    scopus 로고
    • Randomized comparison of a high clopidogrel maintenance dose in patients with diabetes mellitus and coronary artery disease: Results of the Optimizing Antiplatelet Therapy in Diabetes Mellitus (OPTIMUS) study
    • Angiolillo DJ, Shoemaker SB, Desai B, et al. Randomized comparison of a high clopidogrel maintenance dose in patients with diabetes mellitus and coronary artery disease: Results of the Optimizing Antiplatelet Therapy in Diabetes Mellitus (OPTIMUS) study. Circulation 2007 115 : 708 716.
    • (2007) Circulation , vol.115 , pp. 708-716
    • Angiolillo, D.J.1    Shoemaker, S.B.2    Desai, B.3
  • 23
    • 34248397644 scopus 로고    scopus 로고
    • A double-blind, randomized study on platelet aggregation in patients treated with a daily dose of 150 or 75 mg of clopidogrel for 30 days
    • von Beckerath N, Kastrati A, Wieczorek A, et al. A double-blind, randomized study on platelet aggregation in patients treated with a daily dose of 150 or 75 mg of clopidogrel for 30 days. Eur Heart J 2007 28 : 1814 1819.
    • (2007) Eur Heart J , vol.28 , pp. 1814-1819
    • Von Beckerath, N.1    Kastrati, A.2    Wieczorek, A.3
  • 24
    • 38349137324 scopus 로고    scopus 로고
    • Functional impact of high clopidogrel maintenance dosing in patients undergoing elective percutaneous coronary interventions. Results of a randomized study
    • Angiolillo DJ, Bernardo E, Palazuelos J, et al. Functional impact of high clopidogrel maintenance dosing in patients undergoing elective percutaneous coronary interventions. Results of a randomized study. Thromb Haemost 2008 99 : 161 168.
    • (2008) Thromb Haemost , vol.99 , pp. 161-168
    • Angiolillo, D.J.1    Bernardo, E.2    Palazuelos, J.3
  • 25
    • 33846202116 scopus 로고    scopus 로고
    • Effect of timing of clopidogrel administration on 30-day clinical outcomes: 300-mg loading dose immediately after coronary stenting versus pretreatment 6 to 24 hours before stenting in a large unselected patient cohort
    • Szuk T, Gyongyosi M, Homorodi N, et al. Effect of timing of clopidogrel administration on 30-day clinical outcomes: 300-mg loading dose immediately after coronary stenting versus pretreatment 6 to 24 hours before stenting in a large unselected patient cohort. Am Heart J 2007 153 : 289 295.
    • (2007) Am Heart J , vol.153 , pp. 289-295
    • Szuk, T.1    Gyongyosi, M.2    Homorodi, N.3
  • 26
    • 27844531581 scopus 로고    scopus 로고
    • Platelet hyper-function in acute coronary syndromes
    • Harrison P, Mackie I, Mathur A, et al. Platelet hyper-function in acute coronary syndromes. Blood Coagul Fibrinolysis 2005 16 : 557 562.
    • (2005) Blood Coagul Fibrinolysis , vol.16 , pp. 557-562
    • Harrison, P.1    MacKie, I.2    Mathur, A.3
  • 27
    • 27744516843 scopus 로고    scopus 로고
    • Absorption, metabolization, and antiplatelet effects of 300-, 600-, and 900-mg loading doses of clopidogrel: Results of the ISAR-CHOICE (intracoronary stenting and antithrombotic regimen: Choose between 3 high oral doses for immediate clopidogrel effect) trial
    • von Beckerath N, Taubert D, Pogatsa-Murray G, et al. Absorption, metabolization, and antiplatelet effects of 300-, 600-, and 900-mg loading doses of clopidogrel: Results of the ISAR-CHOICE (intracoronary stenting and antithrombotic regimen: Choose between 3 high oral doses for immediate clopidogrel effect) trial. Circulation 2005 112 : 2946 2950.
    • (2005) Circulation , vol.112 , pp. 2946-2950
    • Von Beckerath, N.1    Taubert, D.2    Pogatsa-Murray, G.3
  • 28
    • 33747874088 scopus 로고    scopus 로고
    • A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: The ALBION (assessment of the best loading dose of clopidogrel to blunt platelet activation, inflammation and ongoing necrosis) trial
    • Montalescot G, Sideris G, Meuleman C, et al. A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: The ALBION (assessment of the best loading dose of clopidogrel to blunt platelet activation, inflammation and ongoing necrosis) trial. J Am Coll Cardiol 2006 48 : 931 938.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 931-938
    • Montalescot, G.1    Sideris, G.2    Meuleman, C.3
  • 29
    • 38649131003 scopus 로고    scopus 로고
    • Biological effect of increased maintenance dose of clopidogrel in cardiovascular outpatients and influence of the cytochrome P450 2C19*2 allele on clopidogrel responsiveness
    • Fontana P, Senouf D, Mach F. Biological effect of increased maintenance dose of clopidogrel in cardiovascular outpatients and influence of the cytochrome P450 2C19*2 allele on clopidogrel responsiveness. Thromb Res 2008 121 : 463 468.
    • (2008) Thromb Res , vol.121 , pp. 463-468
    • Fontana, P.1    Senouf, D.2    MacH, F.3
  • 30
    • 4444353174 scopus 로고    scopus 로고
    • Pharmacokinetics of clopidogrel after administration of a high loading dose
    • Taubert D, Kastrati A, Harlfinger S, et al. Pharmacokinetics of clopidogrel after administration of a high loading dose. Thromb Haemost 2004 92 : 311 316.
    • (2004) Thromb Haemost , vol.92 , pp. 311-316
    • Taubert, D.1    Kastrati, A.2    Harlfinger, S.3
  • 31
    • 34250020766 scopus 로고    scopus 로고
    • Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis
    • Buonamici P, Marcucci R, Migliorini A, et al. Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis. J Am Coll Cardiol 2007 49 : 2312 2317.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 2312-2317
    • Buonamici, P.1    Marcucci, R.2    Migliorini, A.3
  • 32
    • 33644587565 scopus 로고    scopus 로고
    • Optimal timing for the initiation of pre-treatment with 300 mg clopidogrel before percutaneous coronary intervention
    • Steinhubl SR, Berger PB, Brennan DM, et al. Optimal timing for the initiation of pre-treatment with 300 mg clopidogrel before percutaneous coronary intervention. J Am Coll Cardiol 2006 47 : 939 943.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 939-943
    • Steinhubl, S.R.1    Berger, P.B.2    Brennan, D.M.3
  • 34
    • 41249093357 scopus 로고    scopus 로고
    • Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance: A multicenter randomized prospective study
    • Bonello L, Camoin-Jau L, Arques S, et al. Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance: A multicenter randomized prospective study. J Am Coll Cardiol 2008 51 : 1404 1411.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1404-1411
    • Bonello, L.1    Camoin-Jau, L.2    Arques, S.3
  • 35
    • 33645982865 scopus 로고    scopus 로고
    • High post-treatment platelet reactivity identified low-responders to dual antiplatelet therapy at increased risk of recurrent cardiovascular events after stenting for acute coronary syndrome
    • Cuisset T, Frere C, Quilici J, et al. High post-treatment platelet reactivity identified low-responders to dual antiplatelet therapy at increased risk of recurrent cardiovascular events after stenting for acute coronary syndrome. J Thromb Haemost 2006 4 : 542 549.
    • (2006) J Thromb Haemost , vol.4 , pp. 542-549
    • Cuisset, T.1    Frere, C.2    Quilici, J.3
  • 36
    • 34548077770 scopus 로고    scopus 로고
    • Platelet function, antiplatelet therapy and clinical outcomes: To test or not to test?
    • de Gaetano G, Cerletti C. Platelet function, antiplatelet therapy and clinical outcomes: To test or not to test? J Thromb Haemost 2007 5 : 1835 1838.
    • (2007) J Thromb Haemost , vol.5 , pp. 1835-1838
    • De Gaetano, G.1    Cerletti, C.2
  • 37
    • 34548075511 scopus 로고    scopus 로고
    • Different methodologies for evaluating the effect of clopidogrel on platelet function in high-risk coronary artery disease patients
    • Paniccia R, Antonucci E, Gori AM, et al. Different methodologies for evaluating the effect of clopidogrel on platelet function in high-risk coronary artery disease patients. J Thromb Haemost 2007 5 : 1839 1847.
    • (2007) J Thromb Haemost , vol.5 , pp. 1839-1847
    • Paniccia, R.1    Antonucci, E.2    Gori, A.M.3
  • 38
    • 57349185925 scopus 로고    scopus 로고
    • Comparison of four tests to assess inhibition of platelet function by clopidogrel in stable coronary artery disease patients
    • Lordkipanidzé M, Pharand C, Nguyen TA, et al. Comparison of four tests to assess inhibition of platelet function by clopidogrel in stable coronary artery disease patients. Eur Heart J 2008 29 : 2877 2885.
    • (2008) Eur Heart J , vol.29 , pp. 2877-2885
    • Lordkipanidzé, M.1    Pharand, C.2    Nguyen, T.A.3


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