Enterohemorrhagic Escherichia coli trivalent recombinant vaccine containing EspA, intimin and Stx2 induces strong humoral immune response and confers protection in mice

Microbes and Infection

Volumn 11, Issue 10-11, 2009, Pages 835-841

  Gu, Jiang ^a   Liu, Yanqing ^a   Yu, Shu ^a   Wang, Haiguang ^a   Wang, Qingxu ^a   Yi, Yong ^a   Zhu, Fengcai ^b   Yu, Xue jie ^c   Zou, Quanming ^a   Mao, Xuhu ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b JIANGSU PROVINCIAL CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

E. coli secreted protein A; Enterohemorrhagic Escherichia coli; Intimin; Shiga toxin; Trivalent subunit vaccine

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL PROTEIN; DRINKING WATER; ESCHERICHIA COLI SECRETED PROTEIN A; IMMUNOGLOBULIN G ANTIBODY; INTIMIN; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; RECOMBINANT PROTEIN; RECOMBINANT VACCINE; STREPTOMYCIN; SUBUNIT VACCINE; VEROTOXIN 2; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; BACTERIAL VIRULENCE; CONTROLLED STUDY; ENTEROHEMORRHAGIC ESCHERICHIA COLI; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GRAM NEGATIVE INFECTION; HEMOLYTIC UREMIC SYNDROME; HEMORRHAGIC COLITIS; HUMORAL IMMUNITY; IMMUNIZATION; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEROCONVERSION; TREATMENT OUTCOME; VACCINE PRODUCTION;

ADHESINS, BACTERIAL; ANIMALS; ANTIBODIES, BACTERIAL; COLONY COUNT, MICROBIAL; ENTEROHEMORRHAGIC ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; ESCHERICHIA COLI PROTEINS; ESCHERICHIA COLI VACCINES; HELA CELLS; HUMANS; MICE; MICE, INBRED BALB C; NEUTRALIZATION TESTS; RECOMBINANT FUSION PROTEINS; SHIGA TOXIN 2; SURVIVAL ANALYSIS; VACCINES, SYNTHETIC;

ESCHERICHIA COLI; MUS;

EID: 68849089748     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2009.04.024     Document Type: Article

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