Measurement of solute transport in the endothelial glycocalyx using indicator dilution techniques

Annals of Biomedical Engineering

Volumn 37, Issue 9, 2009, Pages 1781-1795

  Gao, Lujia ^a   Lipowsky, Herbert H ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Diffusion coefficient; Glycocalyx; Hydraulic resistance; Indicator dispersion; Solute transport

Indexed keywords

AQUEOUS MEDIA; AXIAL DIRECTION; CONSTANT THICKNESS; DIFFUSION COEFFICIENT; DIFFUSION COEFFICIENTS; DILUTION TECHNIQUE; DISPERSION OF SOLUTES; EFFECTIVE DIFFUSION COEFFICIENTS; FIRST MOMENTS; FLUID FLOW; FLUORESCENCE INTENSITIES; GLYCOCALYX; HYDRAULIC RESISTANCE; HYDRAULIC RESISTANCES; IN-VIVO MEASUREMENT; INDEPENDENT VARIABLES; INDICATOR DISPERSION; INFLAMMATORY PROCESS; OFFLINE; RADIAL GRADIENT; RADIAL POSITION; SUPERFUSION; TIME CURVES; TRANSIT TIME;

CELL MEMBRANES; COMPUTER SIMULATION; DIFFUSERS (OPTICAL); DIFFUSION; ENDOTHELIAL CELLS; FLOW OF FLUIDS; FLUORESCENCE; HYDRAULICS; SELF ASSEMBLY; SOLUTE TRANSPORT; STREAM FLOW;

DISPERSIONS;

DEXTRAN; DRUG DERIVATIVE; FLUORESCEIN ISOTHIOCYANATE; FLUORESCEIN ISOTHIOCYANATE DEXTRAN;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; GLYCOCALYX; MALE; PHYSIOLOGY; RAT; SPLANCHNIC BLOOD FLOW; TRANSPORT AT THE CELLULAR LEVEL; VASCULAR ENDOTHELIUM; VENULE; WISTAR RAT;

ANIMALS; BIOLOGICAL TRANSPORT; DEXTRANS; ENDOTHELIUM, VASCULAR; FLUORESCEIN-5-ISOTHIOCYANATE; GLYCOCALYX; MALE; MODELS, CARDIOVASCULAR; RATS; RATS, WISTAR; SPLANCHNIC CIRCULATION; VENULES;

EID: 68749117430     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-009-9743-9     Document Type: Article

References (40)

1. T Abrahamsson U Brandt SL Marklund PO Sjoqvist 1992 Vascular bound recombinant extracellular superoxide dismutase type C protects against the detrimental effects of superoxide radicals on endothelium-dependent arterial relaxation Circ. Res. 70 264 271
2. RH Adamson 1990 Permeability of frog mesenteric capillaries after partial pronase digestion of the endothelial glycocalyx J. Physiol. 428 1 13
3. RH Adamson G Clough 1992 Plasma proteins modify the endothelial cell glycocalyx of frog mesenteric microvessels J. Physiol. 445 473 486
4. AA Constantinescu H Vink JA Spaan 2003 Endothelial cell glycocalyx modulates immobilization of leukocytes at the endothelial surface Arterioscler. Thromb. Vasc. Biol. 23 1541 1547
5. FE Curry CC Michel 1980 A fiber matrix model of capillary permeability Microvasc. Res. 20 96 99
6. C Desjardins BR Duling 1990 Heparinase treatment suggests a role for the endothelial cell glycocalyx in regulation of capillary hematocrit Am. J. Physiol. 258 H647 H654
7. M Gouverneur B Berg M Nieuwdorp E Stroes H Vink 2006 Vasculoprotective properties of the endothelial glycocalyx: effects of fluid shear stress J. Intern. Med. 259 393 400
8. VH Huxley DA Williams 2000 Role of a glycocalyx on coronary arteriole permeability to proteins: evidence from enzyme treatments Am. J. Physiol. Heart Circ. Physiol. 278 H1177 H1185
9. HH Lipowsky LE Cram W Justice MJ Eppihimer 1993 Effect of erythrocyte deformability on in vivo red cell transit time and hematocrit and their correlation with in vitro filterability Microvasc. Res. 46 43 64
10. HH Lipowsky BW Zweifach 1978 Application of the "two-slit" photometric technique to the measurement of microvascular volumetric flow rates Microvasc. Res. 15 93 101
11. JH Luft 1966 Fine structures of capillary and endocapillary layer as revealed by ruthenium red Fed. Proc. 25 1773 1783
12. CB McKay HH Lipowsky 1988 Arteriovenous distribution of transit times in cremaster muscle of the rat Microvasc. Res. 36 75 91
13. P Meier K Zierler 1954 On the theory of the indicator-dilution method for measurement of blood flow and volume J. Appl. Physiol. 6 731 744
14. CC Michel FE Curry 1999 Microvascular permeability Physiol. Rev. 79 703 761
15. AW Mulivor HH Lipowsky 2002 Role of glycocalyx in leukocyte-endothelial cell adhesion Am. J. Physiol. Heart Circ. Physiol. 283 H1282 H1291
16. AW Mulivor HH Lipowsky 2004 Inflammation- and ischemia-induced shedding of venular glycocalyx Am. J. Physiol. Heart Circ. Physiol. 286 H1672 H1680
17. LJ Nugent RK Jain 1984 Plasma pharmacokinetics and interstitial diffusion of macromolecules in a capillary bed Am. J. Physiol. 246 H129 H137
18. LJ Nugent RK Jain 1984 Pore and fiber-matrix models for diffusive transport in normal and neoplastic tissues Microvasc. Res. 28 270 274
19. A Oohira TN Wight P Bornstein 1983 Sulfated proteoglycans synthesized by vascular endothelial cells in culture J. Biol. Chem. 258 2014 2021
20. MJ Pearson HH Lipowsky 2000 Influence of erythrocyte aggregation on leukocyte margination in postcapillary venules of rat mesentery Am. J. Physiol. Heart Circ. Physiol. 279 H1460 H1471
21. N Periasamy AS Verkman 1998 Analysis of fluorophore diffusion by continuous distributions of diffusion coefficients: application to photobleaching measurements of multicomponent and anomalous diffusion Biophys. J. 75 557 567
22. RN Pittman ML Ellsworth 1986 Estimation of red cell flow microvessels: consequences of the Baker-Wayland spatial averaging model Microvasc. Res. 32 371 388
23. DR Potter ER Damiano 2008 The hydrodynamically relevant endothelial cell glycocalyx observed in vivo is absent in vitro Circ. Res. 102 770 776
24. AR Pries TW Secomb P Gaehtgens 2000 The endothelial surface layer Pflugers Arch. 440 653 666
25. NS Quinsey AL Greedy SP Bottomley JC Whisstock RN Pike 2004 Antithrombin: in control of coagulation Int. J. Biochem. Cell Biol. 36 386 389
26. S Reitsma DW Slaaf H Vink MA van Zandvoort MG Oude Egbrink 2007 The endothelial glycocalyx: composition, functions, and visualization Pflugers Arch. 454 345 359
27. TW Secomb R Hsu AR Pries 1998 A model for red blood cell motion in glycocalyx-lined capillaries Am. J. Physiol. 274 H1016 H1022
28. M Sharan AS Popel 2001 A two-phase model for flow of blood in narrow tubes with increased effective viscosity near the wall Biorheology 38 415 428
29. ML Smith DS Long ER Damiano K Ley 2003 Near-wall micro-PIV reveals a hydrodynamically relevant endothelial surface layer in venules in vivo Biophys. J. 85 637 645
30. EE Spaeth SK Friedlander 1967 The diffusion of oxygen, carbon dioxide, and inert gas in flowing blood Biophys. J. 7 827 851
31. JM Squire M Chew G Nneji C Neal J Barry C Michel 2001 Quasi-periodic substructure in the microvessel endothelial glycocalyx: a possible explanation for molecular filtering? J. Struct. Biol. 136 239 255
32. G Taylor 1953 Dispersion of soluble matter in solvent flowing slowly through a tube Proc. R. Soc. Lond. Ser. A 219 186 203
33. G Taylor 1954 Conditions under which dispersion of a solute in a stream of solvent can be used to measure molecular diffusion Proc. R. Soc. Lond. Ser. A 225 473 477
34. H Vink AA Constantinescu JA Spaan 2000 Oxidized lipoproteins degrade the endothelial surface layer : implications for platelet-endothelial cell adhesion Circulation 101 1500 1502
35. H Vink BR Duling 1996 Identification of distinct luminal domains for macromolecules, erythrocytes, and leukocytes within mammalian capillaries Circ. Res. 79 581 589
36. H Vink BR Duling 2000 Capillary endothelial surface layer selectively reduces plasma solute distribution volume Am. J. Physiol. Heart Circ. Physiol. 278 H285 H289
37. S Weinbaum X Zhang Y Han H Vink SC Cowin 2003 Mechanotransduction and flow across the endothelial glycocalyx Proc. Natl. Acad. Sci. USA 100 7988 7995
38. A Yayon M Klagsbrun JD Esko P Leder DM Ornitz 1991 Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor Cell 64 841 848
39. L Zhu V Castranova P He 2005 fMLP-stimulated neutrophils increase endothelial [Ca2+]i and microvessel permeability in the absence of adhesion: role of reactive oxygen species Am. J. Physiol. Heart Circ. Physiol. 288 H1331 H1338
40. CJ Zuurbier C Demirci A Koeman H Vink C Ince 2005 Short-term hyperglycemia increases endothelial glycocalyx permeability and acutely decreases lineal density of capillaries with flowing red blood cells J. Appl. Physiol. 99 1471 1476