Usefulness of Adjusting for Clinical Covariates to Improve the Ability of B-Type Natriuretic Peptide to Distinguish Cardiac from Noncardiac Dyspnea

American Journal of Cardiology

Volumn 104, Issue 5, 2009, Pages 689-694

  Rogers, R Kevin ^a,b   Stoddard, Gregory J ^b   Greene, Tom ^b   Michaels, Andrew D ^b   Fernandez, Genaro ^b   Freeman, Andrew ^b   Nord, John ^b   Stehlik, Josef ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; CREATININE;

AGED; ARTICLE; BODY MASS; CLINICAL FEATURE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DYSPNEA; EMERGENCY WARD; FEMALE; HEART FAILURE; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

AGE FACTORS; AGED; ATRIAL FIBRILLATION; BODY MASS INDEX; COMORBIDITY; CREATININE; FEMALE; HEART FAILURE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; NATRIURETIC PEPTIDE, BRAIN; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES;

EID: 68749095212     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2009.04.043     Document Type: Article

References (21)

1. Das S.R., Drazner M.H., Dries D.L., Vega G.L., Stanek H.G., Abdullah S.M., Canham R.M., Chung A.K., Leonard D., Wians Jr. F.H., and de Lemos J.A. Impact of body mass and body composition on circulating levels of natriuretic peptides: results from the Dallas Heart Study. Circulation 112 (2005) 2163-2168
2. Horwich T.B., Hamilton M.A., and Fonarow G.C. B-type natriuretic peptide levels in obese patients with advanced heart failure. J Am Coll Cardiol 47 (2006) 85-90
3. Knudsen C.W., Omland T., Clopton P., Westheim A., Wu A.H., Duc P., McCord J., Nowak R.M., Hollander J.E., Storrow A.B., Abraham W.T., McCullough P.A., and Maisel A. Impact of atrial fibrillation on the diagnostic performance of B-type natriuretic peptide concentration in dyspneic patients: an analysis from the breathing not properly multinational study. J Am Coll Cardiol 46 (2005) 838-844
4. Krauser D.G., Lloyd-Jones D.M., Chae C.U., Cameron R., Anwaruddin S., Baggish A.L., Chen A., Tung R., and Januzzi Jr. J.L. Effect of body mass index on natriuretic peptide levels in patients with acute congestive heart failure: a ProBNP investigation of dyspnea in the Emergency Department (PRIDE) substudy. Am Heart J 149 (2005) 744-750
5. Maisel A.S., Clopton P., Krishnaswamy P., Nowak R.M., McCord J., Hollander J.E., Duc P., Omland T., Storrow A.B., Abraham W.T., Wu A.H., Steg G., Westheim A., Knudsen C.W., Perez A., Kazanegra R., Bhalla V., Herrmann H.C., Aumont M.C., and McCullough P.A. Impact of age, race, and sex on the ability of B-type natriuretic peptide to aid in the emergency diagnosis of heart failure: results from the breathing not properly (BNP) multinational study. Am Heart J 147 (2004) 1078-1084
6. McCord J., Mundy B.J., Hudson M.P., Maisel A.S., Hollander J.E., Abraham W.T., Steg P.G., Omland T., Knudsen C.W., Sandberg K.R., and McCullough P.A. Relationship between obesity and B-type natriuretic peptide levels. Arch Intern Med 164 (2004) 2247-2252
7. McCullough P.A., Duc P., Omland T., McCord J., Nowak R.M., Hollander J.E., Herrmann H.C., Steg P.G., Westheim A., Knudsen C.W., Storrow A.B., Abraham W.T., Lamba S., Wu A.H., Perez A., Clopton P., Krishnaswamy P., Kazanegra R., and Maisel A.S. B-type natriuretic peptide and renal function in the diagnosis of heart failure: an analysis from the Breathing Not Properly Multinational Study. Am J Kidney Dis 41 (2003) 571-579
8. McLean A.S., Huang S.J., Nalos M., Tang B., and Stewart D.E. The confounding effects of age, gender, serum creatinine, and electrolyte concentrations on plasma B-type natriuretic peptide concentrations in critically ill patients. Crit Care Med 31 (2003) 2611-2618
9. Mehra M.R., Uber P.A., Park M.H., Scott R.L., Ventura H.O., Harris B.C., and Frohlich E.D. Obesity and suppressed B-type natriuretic peptide levels in heart failure. J Am Coll Cardiol 43 (2004) 1590-1595
10. Raymond I., Groenning B.A., Hildebrandt P.R., Nilsson J.C., Baumann M., Trawinski J., and Pedersen F. The influence of age, sex and other variables on the plasma level of N-terminal pro brain natriuretic peptide in a large sample of the general population. Heart 89 (2003) 745-751
11. Daniels L.B., and Maisel A.S. Natriuretic peptides. J Am Coll Cardiol 50 (2007) 2357-2368
12. Daniels L.B., Clopton P., Bhalla V., Krishnaswamy P., Nowak R.M., McCord J., Hollander J.E., Duc P., Omland T., Storrow A.B., Abraham W.T., Wu A.H., Steg P.G., Westheim A., Knudsen C.W., Perez A., Kazanegra R., Herrmann H.C., McCullough P.A., and Maisel A.S. How obesity affects the cut-points for B-type natriuretic peptide in the diagnosis of acute heart failure. Results from the breathing not properly multinational study. Am Heart J 151 (2006) 999-1005
13. Knudsen C.W., Clopton P., Westheim A., Klemsdal T.O., Wu A.H., Duc P., McCord J., Nowak R.M., Hollander J.E., Storrow A.B., Abraham W.T., McCullough P.A., Maisel A.S., and Omland T. Predictors of elevated B-type natriuretic peptide concentrations in dyspneic patients without heart failure: an analysis from the breathing not properly multinational study. Ann Emerg Med 45 (2005) 573-580
14. Wang T.J., Larson M.G., Levy D., Benjamin E.J., Leip E.P., Wilson P.W., and Vasan R.S. Impact of obesity on plasma natriuretic peptide levels. Circulation 109 (2004) 594-600
15. Wang T.J., Larson M.G., Levy D., Leip E.P., Benjamin E.J., Wilson P.W., Sutherland P., Omland T., and Vasan R.S. Impact of age and sex on plasma natriuretic peptide levels in healthy adults. Am J Cardiol 90 (2002) 254-258
16. McKee P.A., Castelli W.P., McNamara P.M., and Kannel W.B. The natural history of congestive heart failure: the Framingham study. N Engl J Med 285 (1971) 1441-1446
17. DeLong ER D.D., and Clark-Pearson D.L. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 44 (1988) 837-845
18. Harrell Jr. F.E., Lee K.L., and Mark D.B. Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med 15 (1996) 361-387
19. Pencina M.J., D'Agostino Sr. R.B., D'Agostino Jr. R.B., and Vasan R.S. Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med 27 (2008) 157-172 207-212
20. Maisel A.S., Krishnaswamy P., Nowak R.M., McCord J., Hollander J.E., Duc P., Omland T., Storrow A.B., Abraham W.T., Wu A.H., Clopton P., Steg P.G., Westheim A., Knudsen C.W., Perez A., Kazanegra R., Herrmann H.C., and McCullough P.A. Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure. N Engl J Med 347 (2002) 161-167
21. Peacock W.F., Mueller C., Disomma S., and Maisel A. Emergency department perspectives on B-type natriuretic peptide utility. Congest Heart Fail 14 (2008) 17-20