-
2
-
-
0032110436
-
in individuals with severe deficiency of alpha1-antitrypsin
-
in individuals with severe deficiency of alpha1-antitrypsin. Am J Respir Crit Care Med 158: 49–59.
-
Am J Respir Crit Care Med
, vol.158
, pp. 49-59
-
-
-
4
-
-
0028234884
-
Replacement therapy for hereditary alpha-1-antitrypsin deficiency. A program for long-term administration
-
Barker, A.F., Siemsen, F., Pasley, D., D'Silva, R., Buist, A.S. (1994) Replacement therapy for hereditary alpha-1-antitrypsin deficiency. A program for long-term administration. Chest 105: 1406–1410.
-
(1994)
Chest
, vol.105
, pp. 1406-1410
-
-
Barker, A.F.1
Siemsen, F.2
Pasley, D.3
D'Silva, R.4
Buist, A.S.5
-
5
-
-
34250757699
-
Identification on individuals with alpha-1-antitrypsin deficiency by a targeted screening program
-
Bals, R., Koczulla, R., Kokte, V., Andress, J., Blackert, K. and Vogelmeier, C. (2007) Identification on individuals with alpha-1-antitrypsin deficiency by a targeted screening program. Respir, Med 101: 1708–1714.
-
(2007)
Respir, Med
, vol.101
, pp. 1708-1714
-
-
Bals, R.1
Koczulla, R.2
Kokte, V.3
Andress, J.4
Blackert, K.5
Vogelmeier, C.6
-
6
-
-
30744432675
-
Estimates of the prevalence of alpha-1-antitrypsin deficiency PI*S and PI*Z alleles and the numbers at risk in European countries
-
Blanco, I., de Serres, F.J., Fernández-Bustillo, E., Lara, B., Miravitlles, M. (2006) Estimates of the prevalence of alpha-1-antitrypsin deficiency PI*S and PI*Z alleles and the numbers at risk in European countries. Eur Respir J 27: 77–84.
-
(2006)
Eur Respir J
, vol.27
, pp. 77-84
-
-
Blanco, I.1
de Serres, F.J.2
Fernández-Bustillo, E.3
Lara, B.4
Miravitlles, M.5
-
7
-
-
24944447780
-
Trends in the diagnosis of symptomatic patients with alpha-1 antitrypsin deficiency between 1968 and 2003
-
Campos, M.A., Wanner, A., Zhang, G., Sandhaus, R.A. (2005) Trends in the diagnosis of symptomatic patients with alpha-1 antitrypsin deficiency between 1968 and 2003. Chest 128: 1179–1186.
-
(2005)
Chest
, vol.128
, pp. 1179-1186
-
-
Campos, M.A.1
Wanner, A.2
Zhang, G.3
Sandhaus, R.A.4
-
8
-
-
0031729164
-
Two-year results after lung volume reduction surgery in alpha-1-antitrypsin deficiency versus smoker's emphysema
-
Cassina, P.C., Teschler, H., Konietzko, N., Theegarten, D., Stamatis, G. (1998) Two-year results after lung volume reduction surgery in alpha-1-antitrypsin deficiency versus smoker's emphysema. Eur Respir J 12: 1028–1032.
-
(1998)
Eur Respir J
, vol.12
, pp. 1028-1032
-
-
Cassina, P.C.1
Teschler, H.2
Konietzko, N.3
Theegarten, D.4
Stamatis, G.5
-
9
-
-
32644443859
-
Diagnostic flow chart for targeted detection of alpha-1-antitrypsin deficiency
-
Corda, L., Bertella, E., Pini, L., Pezzini, A., Medicina, D., Boni, E. et al. (2006) Diagnostic flow chart for targeted detection of alpha-1-antitrypsin deficiency. Respir Med 100: 463–470.
-
(2006)
Respir Med
, vol.100
, pp. 463-470
-
-
Corda, L.1
Bertella, E.2
Pini, L.3
Pezzini, A.4
Medicina, D.5
Boni, E.6
-
10
-
-
26844495296
-
Results of a case-detection programme for alpha-1-antitrypsin deficiency in COPD patients
-
De la Roza, C., Rodríguez-Frías, F., Lara, B., Vidal, R., Jardí, R., Miravitlles, M. (2005) Results of a case-detection programme for alpha-1-antitrypsin deficiency in COPD patients. Eur Respir J 26: 616–622.
-
(2005)
Eur Respir J
, vol.26
, pp. 616-622
-
-
De la Roza, C.1
Rodríguez-Frías, F.2
Lara, B.3
Vidal, R.4
Jardí, R.5
Miravitlles, M.6
-
11
-
-
33745924405
-
Alpha-1-antitrypsin deficiency: situation in Spain and development of a screening program
-
De la Roza, C., Lara, B., Vilà, S., Miravitlles, M. (2006) Alpha-1-antitrypsin deficiency: situation in Spain and development of a screening program. Arch Bronconeumol 42: 290–298.
-
(2006)
Arch Bronconeumol
, vol.42
, pp. 290-298
-
-
De la Roza, C.1
Lara, B.2
Vilà, S.3
Miravitlles, M.4
-
12
-
-
35548952828
-
Determinants of airflow obstruction in severe alpha-1-antitrypsin deficiency
-
DeMeo, D.L., Sandhaus, R.A., Barker, A.F., Brantly, M.L., Eden, E., McElvany, N.G. et al. (2007) Determinants of airflow obstruction in severe alpha-1-antitrypsin deficiency. Thorax 62: 805–812.
-
(2007)
Thorax
, vol.62
, pp. 805-812
-
-
DeMeo, D.L.1
Sandhaus, R.A.2
Barker, A.F.3
Brantly, M.L.4
Eden, E.5
McElvany, N.G.6
-
13
-
-
0032724157
-
A randomized clinical trial of alpha-1-antitrypsin augmentation therapy
-
Dirksen, A., Dijkman, J.H., Madsen, F., Stoel, B., Hutchison, D.C., Ulrik, C.S. et al. (1999) A randomized clinical trial of alpha-1-antitrypsin augmentation therapy. Am J Respir Crit Care Med 160: 1468–1472.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1468-1472
-
-
Dirksen, A.1
Dijkman, J.H.2
Madsen, F.3
Stoel, B.4
Hutchison, D.C.5
Ulrik, C.S.6
-
14
-
-
0033428850
-
Evidence for excessive bronchial inflammation during an acute exacerbation of chronic obstructive pulmonary disease in patients with alpha-1-antitrypsin deficiency (PiZ)
-
Hill, A.T., Campbell, E.J., Bayley, D.L., Hill, S.L., Stockley, R.A. (1999) Evidence for excessive bronchial inflammation during an acute exacerbation of chronic obstructive pulmonary disease in patients with alpha-1-antitrypsin deficiency (PiZ). Am J Respir Crit Care Med 160: 1968–1975.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1968-1975
-
-
Hill, A.T.1
Campbell, E.J.2
Bayley, D.L.3
Hill, S.L.4
Stockley, R.A.5
-
15
-
-
0023784904
-
Biochemical efficacy and safety of monthly augmentation therapy for alpha-1-antitrypsin deficiency
-
Hubbard, R.C., Sellers, S., Czerski, D., Stephens, L., Crystal, R.G. (1988) Biochemical efficacy and safety of monthly augmentation therapy for alpha-1-antitrypsin deficiency. JAMA 260: 1259–1264.
-
(1988)
JAMA
, vol.260
, pp. 1259-1264
-
-
Hubbard, R.C.1
Sellers, S.2
Czerski, D.3
Stephens, L.4
Crystal, R.G.5
-
16
-
-
36148968064
-
Development and results of the Spanish registry of patients with alpha-1 antitrypsin deficiency
-
Lara, B., de la Roza, C., Vilà, S., Vidal, R., Miravitlles, M. (2007) Development and results of the Spanish registry of patients with alpha-1 antitrypsin deficiency. Int J COPD 2: 393–398.
-
(2007)
Int J COPD
, vol.2
, pp. 393-398
-
-
Lara, B.1
de la Roza, C.2
Vilà, S.3
Vidal, R.4
Miravitlles, M.5
-
17
-
-
0033739182
-
Augmentation therapy reduces frequency of lung infections in antitrypsin deficiency: a new hypothesis with supporting data
-
Lieberman, J. (2000) Augmentation therapy reduces frequency of lung infections in antitrypsin deficiency: a new hypothesis with supporting data. Chest 118: 1480–1485.
-
(2000)
Chest
, vol.118
, pp. 1480-1485
-
-
Lieberman, J.1
-
18
-
-
0036771798
-
Alpha-1-antitrypsin deficiency: a report from the 2nd meeting of the Alpha One International Registry, Rapallo (Genova, Italy), 2001
-
Luisetti, M., Miravitlles, M., Stockley, R.A. (2002) Alpha-1-antitrypsin deficiency: a report from the 2nd meeting of the Alpha One International Registry, Rapallo (Genova, Italy), 2001. Eur Respir J 20: 1050–1056.
-
(2002)
Eur Respir J
, vol.20
, pp. 1050-1056
-
-
Luisetti, M.1
Miravitlles, M.2
Stockley, R.A.3
-
19
-
-
0033052583
-
A national program for detection of alpha1-antitrypsin deficiency in Italy
-
Luisetti, M., Massi, G., Massobrio, M., Guarraci, P., Menchicchi, M. (1999) A national program for detection of alpha1-antitrypsin deficiency in Italy. Respir Med 93: 169–172.
-
(1999)
Respir Med
, vol.93
, pp. 169-172
-
-
Luisetti, M.1
Massi, G.2
Massobrio, M.3
Guarraci, P.4
Menchicchi, M.5
-
20
-
-
2642680855
-
Alpha1-antitrypsin deficiency: memorandum from a WHO meeting
-
Memoranda WHO. (1997) Alpha1-antitrypsin deficiency: memorandum from a WHO meeting. Bull WHO 75: 397–415.
-
(1997)
Bull WHO
, vol.75
, pp. 397-415
-
-
Memoranda WHO.1
-
21
-
-
0028603327
-
Evaluación del tratamiento sustitutivo del enfisema por déficit de alfa-1-antitripsina
-
Miravitlles, M., Vidal, R., Torrella, M., Bofill, J.M., Cotrina, M., de Gracia, J. (1994) Evaluación del tratamiento sustitutivo del enfisema por déficit de alfa-1-antitripsina. Arch Bronconeumol 30: 479–484.
-
(1994)
Arch Bronconeumol
, vol.30
, pp. 479-484
-
-
Miravitlles, M.1
Vidal, R.2
Torrella, M.3
Bofill, J.M.4
Cotrina, M.5
de Gracia, J.6
-
22
-
-
0031756969
-
Usefulness of a national Registry of alpha-1-antitrypsin deficiency. The Spanish experience
-
Miravitlles, M., Vidal, R., Barros-Tizón, J.C., Bustamante, A., España, P.P., Casas, F. et al. (1998) Usefulness of a national Registry of alpha-1-antitrypsin deficiency. The Spanish experience. Respir Med 92: 1181–1187.
-
(1998)
Respir Med
, vol.92
, pp. 1181-1187
-
-
Miravitlles, M.1
Vidal, R.2
Barros-Tizón, J.C.3
Bustamante, A.4
España, P.P.5
Casas, F.6
-
23
-
-
0032693588
-
Specific antibody response against the 23-valent pneumococcal vaccine in patients with alpha-1-antitrypsin deficiency with and without bronchiectasis
-
Miravitlles, M., de Gracia, J., Rodrigo, M.J., Cruz, M.J., Vendrell, M., Vidal, R. et al. (1999a) Specific antibody response against the 23-valent pneumococcal vaccine in patients with alpha-1-antitrypsin deficiency with and without bronchiectasis. Chest 116: 946–952.
-
(1999)
Chest
, vol.116
, pp. 946-952
-
-
Miravitlles, M.1
de Gracia, J.2
Rodrigo, M.J.3
Cruz, M.J.4
Vendrell, M.5
Vidal, R.6
-
24
-
-
0033501497
-
Estado actual del tratamiento sustitutivo en el enfisema congénito por déficit de alfa-1-antitripsina. Informe del Registro Nacional
-
Miravitlles, M., Vidal, R., Barros-Tizón, J.C., Bustamante, A., España, P.P., Casas, F. et al. (1999b) Estado actual del tratamiento sustitutivo en el enfisema congénito por déficit de alfa-1-antitripsina. Informe del Registro Nacional. Arch Bronconeumol 35: 446–454.
-
(1999)
Arch Bronconeumol
, vol.35
, pp. 446-454
-
-
Miravitlles, M.1
Vidal, R.2
Barros-Tizón, J.C.3
Bustamante, A.4
España, P.P.5
Casas, F.6
-
25
-
-
22544438725
-
Tratamiento de la enfermedad pulmonar obstructiva crónica
-
Miravitlles, M. (2005) Tratamiento de la enfermedad pulmonar obstructiva crónica. Med Clin (Barc) 125: 65–74.
-
(2005)
Med Clin (Barc)
, vol.125
, pp. 65-74
-
-
Miravitlles, M.1
-
26
-
-
20444455824
-
Exacerbations in alpha-1-antitrypsin deficiency
-
Needham, M., Stockley, R.A. (2005) Exacerbations in alpha-1-antitrypsin deficiency. Eur Respir J 25: 992–1000.
-
(2005)
Eur Respir J
, vol.25
, pp. 992-1000
-
-
Needham, M.1
Stockley, R.A.2
-
27
-
-
0023925114
-
Replacement therapy for alpha-1-protease inhibitor deficiency in PiZ subjects with chronic obstructive lung disease
-
Suppl 6A:
-
Schmidt, E.W., Rasche, B., Ulmer,W.T., Konietzko, N., Becker, M., Fallise, J.P. et al. (1988) Replacement therapy for alpha-1-protease inhibitor deficiency in PiZ subjects with chronic obstructive lung disease. Am J Med 84 Suppl 6A: 63–69.
-
(1988)
Am J Med
, vol.84
, pp. 63-69
-
-
Schmidt, E.W.1
Rasche, B.2
UlmerW.T.3
Konietzko, N.4
Becker, M.5
Fallise, J.P.6
-
28
-
-
0031017613
-
Long-term augmentation therapy in twenty patients with severe alpha-1-antitrypsin deficiency’ three-year follow-up
-
Schwaiblmair, M., Vogelmeier, C., Fruhmann, G. (1997) Long-term augmentation therapy in twenty patients with severe alpha-1-antitrypsin deficiency’ three-year follow-up. Respiration 64: 10–15.
-
(1997)
Respiration
, vol.64
, pp. 10-15
-
-
Schwaiblmair, M.1
Vogelmeier, C.2
Fruhmann, G.3
-
29
-
-
0031242842
-
Does alpha-1-antitrypsin augmentation therapy slow the annual decline in FEV1 in patients with severe hereditary alpha-1-antitrypsin deficiency? Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen (WATL) alpha1-AT study group
-
Seersholm, N., Wencker, M., Banik, N., Viskum, K., Dirksen, A., Kok-Jensen, A. et al. (1997) Does alpha-1-antitrypsin augmentation therapy slow the annual decline in FEV1 in patients with severe hereditary alpha-1-antitrypsin deficiency? Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen (WATL) alpha1-AT study group. Eur Respir J 10: 2260–2263.
-
(1997)
Eur Respir J
, vol.10
, pp. 2260-2263
-
-
Seersholm, N.1
Wencker, M.2
Banik, N.3
Viskum, K.4
Dirksen, A.5
Kok-Jensen, A.6
-
30
-
-
33845227581
-
Alpha-1-antirypsin deficiency: optimal therapeutic regimen based on population pharmacokinetics
-
Soy, D., de la Roza, C., Lara, B., Esquinas, C., Torres, A., Miravitlles, M. (2006) Alpha-1-antirypsin deficiency: optimal therapeutic regimen based on population pharmacokinetics. Thorax 61: 1059–1064.
-
(2006)
Thorax
, vol.61
, pp. 1059-1064
-
-
Soy, D.1
de la Roza, C.2
Lara, B.3
Esquinas, C.4
Torres, A.5
Miravitlles, M.6
-
31
-
-
0036606880
-
The effect of augmentation therapy on bronchial inflammation in alpha-1-antitrypsin deficiency
-
Stockley, R.A., Bayley, D.L., Unsal, I., Dowson, L.J. (2002) The effect of augmentation therapy on bronchial inflammation in alpha-1-antitrypsin deficiency. Am J Respir Crit Care Med 165: 1494–1498.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 1494-1498
-
-
Stockley, R.A.1
Bayley, D.L.2
Unsal, I.3
Dowson, L.J.4
-
32
-
-
33847750273
-
Ongoing research in Europe: Alpha One International Registry (AIR) objectives and development
-
Stockley, R.A., Luisetti, M., Miravitlles, M., Piitulainen, E., Fernandez, P. and on behalf of the Alpha One International Registry (A.I.R.) group. (2007) Ongoing research in Europe: Alpha One International Registry (AIR) objectives and development. Eur Respir J 29: 582–586.
-
(2007)
Eur Respir J
, vol.29
, pp. 582-586
-
-
Stockley, R.A.1
Luisetti, M.2
Miravitlles, M.3
Piitulainen, E.4
Fernandez, P.5
on behalf of the Alpha One International Registry (A.I.R.) group.6
-
33
-
-
0036301645
-
Biochemical efficacy and safety of a new pooled human plasma alpha(1)-antitrypsin, Respitin
-
Stoller, J.K., Rouhani, F., Brantly, M., Shahin, S., Dweik, R.A., Stocks, J.M. et al. (2002) Biochemical efficacy and safety of a new pooled human plasma alpha(1)-antitrypsin, Respitin. Chest 122: 66–74.
-
(2002)
Chest
, vol.122
, pp. 66-74
-
-
Stoller, J.K.1
Rouhani, F.2
Brantly, M.3
Shahin, S.4
Dweik, R.A.5
Stocks, J.M.6
-
34
-
-
0038216603
-
Augmentation therapy with alpha-1-antitrypsin: patterns of use and adverse events
-
Stoller, J.K., Fallat, R., Schluchter, M.D., O'Brien, R.G., Connor, J.T., Gross, N. et al. (2003) Augmentation therapy with alpha-1-antitrypsin: patterns of use and adverse events. Chest 123: 1425–1434.
-
(2003)
Chest
, vol.123
, pp. 1425-1434
-
-
Stoller, J.K.1
Fallat, R.2
Schluchter, M.D.3
O'Brien, R.G.4
Connor, J.T.5
Gross, N.6
-
35
-
-
4043052858
-
Alpha-1-antitrypsin deficiency. 5: intravenous augmentation therapy: current understanding
-
Stoller, J.K., Aboussonan, L.S. (2004) Alpha-1-antitrypsin deficiency. 5: intravenous augmentation therapy: current understanding. Thorax 59: 708–712.
-
(2004)
Thorax
, vol.59
, pp. 708-712
-
-
Stoller, J.K.1
Aboussonan, L.S.2
-
36
-
-
27144471656
-
Delay in diagnosis of alpha-1-antitrypsin deficiency: a continuing problem
-
Stoller, J.K., Sandhaus, R.A., Turino, G., Dickson, R., Rodgers, K., Strange, C. (2005) Delay in diagnosis of alpha-1-antitrypsin deficiency: a continuing problem. Chest 128: 1989–1994.
-
(2005)
Chest
, vol.128
, pp. 1989-1994
-
-
Stoller, J.K.1
Sandhaus, R.A.2
Turino, G.3
Dickson, R.4
Rodgers, K.5
Strange, C.6
-
37
-
-
33751067225
-
Farmacocinética de la alfa-1-antitripsina utilizada en el tratamiento sustitutivo del enfisema congénito grave
-
Vidal, R., Drobnic, M.E., Sala, F., Padulles, N., Montoro, J.B., Jardí, R. et al. (2006a) Farmacocinética de la alfa-1-antitripsina utilizada en el tratamiento sustitutivo del enfisema congénito grave. Arch Bronconeumol 42: 553–556.
-
(2006)
Arch Bronconeumol
, vol.42
, pp. 553-556
-
-
Vidal, R.1
Drobnic, M.E.2
Sala, F.3
Padulles, N.4
Montoro, J.B.5
Jardí, R.6
-
38
-
-
33846346558
-
y Comité del Registro Nacional de Pacientes con Déficit de Alfa-1-antitripsina. Normativa SEPAR: Diagnóstico y tratamiento del déficit de alfa-1-antitripsina
-
Vidal, R., Blanco, I., Casas, F., Jardí, R., Miravitlles, M. (2006b) y Comité del Registro Nacional de Pacientes con Déficit de Alfa-1-antitripsina. Normativa SEPAR: Diagnóstico y tratamiento del déficit de alfa-1-antitripsina. Arch Bronconeumol 42: 645–659.
-
(2006)
Arch Bronconeumol
, vol.42
, pp. 645-659
-
-
Vidal, R.1
Blanco, I.2
Casas, F.3
Jardí, R.4
Miravitlles, M.5
-
39
-
-
0035095548
-
Longitudinal follow-up of patients with alpha-1-protease inhibitor deficiency before and during therapy with alpha-1-protease inhibitor
-
Wencker, M., Fuhrmann, B., Banik, N., Konietzko, N., for the Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen. (2001) Longitudinal follow-up of patients with alpha-1-protease inhibitor deficiency before and during therapy with alpha-1-protease inhibitor. Chest 119: 737–744.
-
(2001)
Chest
, vol.119
, pp. 737-744
-
-
Wencker, M.1
Fuhrmann, B.2
Banik, N.3
Konietzko, N.4
for the Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen.5
-
40
-
-
0035990476
-
Screening for alpha1-Pi deficiency in patients with lung diseases
-
Wencker, M., Marx, A., Konietzko, N., Schaefer, B., Campbell, E.J. (2002) Screening for alpha1-Pi deficiency in patients with lung diseases. Eur Respir J 20: 319–324.
-
(2002)
Eur Respir J
, vol.20
, pp. 319-324
-
-
Wencker, M.1
Marx, A.2
Konietzko, N.3
Schaefer, B.4
Campbell, E.J.5
-
41
-
-
0023148995
-
Replacement therapy for alpha-1-antitrypsin deficiency associated with emphysema
-
Wewers, M.D., Casolaro, M.A., Sellers, S.E., Swayze, S.C., McPhaul, K.M., Wittes, J.T. et al. (1987) Replacement therapy for alpha-1-antitrypsin deficiency associated with emphysema. N Engl J Med 316: 1055–1062.
-
(1987)
N Engl J Med
, vol.316
, pp. 1055-1062
-
-
Wewers, M.D.1
Casolaro, M.A.2
Sellers, S.E.3
Swayze, S.C.4
McPhaul, K.M.5
Wittes, J.T.6
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