메뉴 건너뛰기




Volumn 1170, Issue , 2009, Pages 610-614

Symposium overview: Do environmental agents enter the brain via the olfactory mucosa to induce neurodegenerative diseases

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; APOLIPOPROTEIN E; CADMIUM; CHOLINERGIC RECEPTOR BLOCKING AGENT; DESIGNER DRUG; DOPAMINE RECEPTOR STIMULATING AGENT; IRON; LEVODOPA; MANGANESE; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; ORGANIC ANION TRANSPORTER 1; PRION PROTEIN;

EID: 68649123827     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.03926.x     Document Type: Conference Paper
Times cited : (10)

References (45)
  • 1
    • 25844524877 scopus 로고    scopus 로고
    • Neurodegenerative diseases: An overview of environmental risk factors
    • Brown, R.C., A.H. Lockwood & B.R. Sonawane. 2005. Neurodegenerative diseases: an overview of environmental risk factors. Environ. Health Perspect. 113:1250-1256.
    • (2005) Environ. Health Perspect , vol.113 , pp. 1250-1256
    • Brown, R.C.1    Lockwood, A.H.2    Sonawane, B.R.3
  • 2
    • 30344489022 scopus 로고    scopus 로고
    • Effect of air pollution on olfactory function in residents of Mexico City
    • Hudson, R. et al. 2006. Effect of air pollution on olfactory function in residents of Mexico City. Chem. Senses 31: 79-85.
    • (2006) Chem. Senses , vol.31 , pp. 79-85
    • Hudson, R.1
  • 3
    • 8544267937 scopus 로고    scopus 로고
    • Brain inflammation and Alzheimer's-like pathology in individuals exposed to severe air pollution
    • Calderon-Garciduenas, L. et al. 2004. Brain inflammation and Alzheimer's-like pathology in individuals exposed to severe air pollution. Toxicol. Pathol. 32:650-658.
    • (2004) Toxicol. Pathol , vol.32 , pp. 650-658
    • Calderon-Garciduenas, L.1
  • 4
    • 34548720470 scopus 로고    scopus 로고
    • San- Francisco/Oakland Bay Bridge welder study: Olfactory function
    • Antunes, M.B., R. Bowler & R.L. Doty. 2007. San- Francisco/Oakland Bay Bridge welder study: olfactory function. Neurology 69: 1278-1284.
    • (2007) Neurology , vol.69 , pp. 1278-1284
    • Antunes, M.B.1    Bowler, R.2    Doty, R.L.3
  • 6
    • 7844235517 scopus 로고
    • A note on the mode of infection in epidemic poliomyelitis
    • Flexner, S. & P.F. Clark. 1912. A note on the mode of infection in epidemic poliomyelitis. Proc. Soc. Exp. Biol. Med. 10: 1-2.
    • (1912) Proc. Soc. Exp. Biol. Med , vol.10 , pp. 1-2
    • Flexner, S.1    Clark, P.F.2
  • 7
    • 33748260783 scopus 로고
    • The portal of entry and transmission of the virus of poliomyelitis
    • Brodie,M. & A.R. Elvidge. 1934. The portal of entry and transmission of the virus of poliomyelitis. Science79: 235-236.
    • (1934) Science , vol.79 , pp. 235-236
    • Brodie, M.1    Elvidge, A.R.2
  • 8
    • 0342494660 scopus 로고
    • Prevention of intranasally inoculated poliomyelitis in monkeys by previous intranasal irrigation with chemical agents
    • Schultz, E.W. & L.P. Gebhardt. 1936. Prevention of intranasally inoculated poliomyelitis in monkeys by previous intranasal irrigation with chemical agents. Proc. Soc. Exp. Biol. Med. 34: 133-135.
    • (1936) Proc. Soc. Exp. Biol. Med , vol.34 , pp. 133-135
    • Schultz, E.W.1    Gebhardt, L.P.2
  • 9
    • 38949176236 scopus 로고
    • Olfactory bulbs in human poliomyelitis
    • Sabin, A.B. 1940. Olfactory bulbs in human poliomyelitis. Am. J. Dis. Child. 60: 1313-1318.
    • (1940) Am. J. Dis. Child , vol.60 , pp. 1313-1318
    • Sabin, A.B.1
  • 10
    • 84964092952 scopus 로고
    • Influence of pathway of infection on pathology of olfactory bulbs in experimental poliomyelitis
    • Sabin, A.B. & P.K. Olitsky. 1936. Influence of pathway of infection on pathology of olfactory bulbs in experimental poliomyelitis. Proc. Soc. Exp. Biol. Med.1936: 300-301.
    • (1936) Proc. Soc. Exp. Biol. Med , vol.1936 , pp. 300-301
    • Sabin, A.B.1    Olitsky, P.K.2
  • 11
    • 33747260491 scopus 로고
    • Zinc-sulphate nasal spray in the prophylaxis of poliomyelitis
    • Tisdall, F.F. et al. 1937. Zinc-sulphate nasal spray in the prophylaxis of poliomyelitis. Can. Public Health J.28: 523-543.
    • (1937) Can. Public Health J , vol.28 , pp. 523-543
    • Tisdall, F.F.1
  • 12
    • 39049153943 scopus 로고    scopus 로고
    • Doty, R.L. 2008. The olfactory vector hypothesis of neurodegenerative disease: is it viable? Ann. Neurol.63: 7-15. 12a.Genter, M.B., E.L. Kendig & M.D. Knutson. 2009. Uptake of materials from the nasal cavity into the blood and brain: are we finally beginning to understand these processes at the molecular level? Ann. N. Y. Acad. Sci. International Symposium on Olfaction and Taste. 1170: 623-628.
    • Doty, R.L. 2008. The olfactory vector hypothesis of neurodegenerative disease: is it viable? Ann. Neurol.63: 7-15. 12a.Genter, M.B., E.L. Kendig & M.D. Knutson. 2009. Uptake of materials from the nasal cavity into the blood and brain: are we finally beginning to understand these processes at the molecular level? Ann. N. Y. Acad. Sci. International Symposium on Olfaction and Taste. 1170: 623-628.
  • 13
    • 0014410437 scopus 로고
    • Pathogenesis for viral infections of nervous system
    • Johnson, R.T. & C.A. Mims. 1968. Pathogenesis for viral infections of nervous system. N. Engl. J. Med.278: 84-92.
    • (1968) N. Engl. J. Med , vol.278 , pp. 84-92
    • Johnson, R.T.1    Mims, C.A.2
  • 14
    • 2342663326 scopus 로고    scopus 로고
    • The olfactory system and the nasal mucosa as portals of entry of viruses, drugs, and other exogenous agents into the brain
    • R.L. Doty, Ed, Marcel Dekker. New York, NY
    • Baker, H. & M.B.Genter. 2003.The olfactory system and the nasal mucosa as portals of entry of viruses, drugs, and other exogenous agents into the brain. In Handbook of Olfaction and Gustation. R.L. Doty, Ed.: 549-573. Marcel Dekker. New York, NY.
    • (2003) Handbook of Olfaction and Gustation , pp. 549-573
    • Baker, H.1    Genter, M.B.2
  • 15
    • 0022477568 scopus 로고
    • Transneuronal transport of peroxidase-conjugated wheat germ agglutinin (WGA-HRP) from the olfactory epithelium to the brain of the adult rat
    • Baker, H. & R.F. Spencer. 1986. Transneuronal transport of peroxidase-conjugated wheat germ agglutinin (WGA-HRP) from the olfactory epithelium to the brain of the adult rat. Exp. Brain Res. 63: 461- 473.
    • (1986) Exp. Brain Res , vol.63 , pp. 461-473
    • Baker, H.1    Spencer, R.F.2
  • 16
    • 0020595817 scopus 로고
    • Mode of entry of a neurotropic virus into the central nervous system: Reinvestigation of an old controversy
    • Monath, T.P., C.B. Croop & A.K. Harrison. 1983. Mode of entry of a neurotropic virus into the central nervous system: reinvestigation of an old controversy. Lab. Invest. 48: 399-410.
    • (1983) Lab. Invest , vol.48 , pp. 399-410
    • Monath, T.P.1    Croop, C.B.2    Harrison, A.K.3
  • 17
    • 0033042991 scopus 로고    scopus 로고
    • Uptake of metals in the brain via olfactory pathways
    • Tjalve,H. & J. Henriksson. 1999. Uptake of metals in the brain via olfactory pathways. Neurotoxicology 20:181-195.
    • (1999) Neurotoxicology , vol.20 , pp. 181-195
    • Tjalve, H.1    Henriksson, J.2
  • 18
    • 0034041099 scopus 로고    scopus 로고
    • Manganese taken up into the CNS via the olfactory pathway in rats affects astrocytes
    • Henriksson, J. & H. Tjalve. 2000. Manganese taken up into the CNS via the olfactory pathway in rats affects astrocytes. Toxicol. Sci. 55: 392- 398.
    • (2000) Toxicol. Sci , vol.55 , pp. 392-398
    • Henriksson, J.1    Tjalve, H.2
  • 19
    • 0030936838 scopus 로고    scopus 로고
    • Effects of dichlobenil on ultrastructural morphology and cell replication in the mouse olfactory mucosa
    • Mancuso, M., A. Giovanetti & E.B. Brittebo. 1997. Effects of dichlobenil on ultrastructural morphology and cell replication in the mouse olfactory mucosa. Toxicol. Pathol. 25: 186-194.
    • (1997) Toxicol. Pathol , vol.25 , pp. 186-194
    • Mancuso, M.1    Giovanetti, A.2    Brittebo, E.B.3
  • 20
    • 0023204475 scopus 로고
    • Uptake and specific binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the olfactory mucosa of mice and rats
    • Gillner, M. et al. 1987. Uptake and specific binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the olfactory mucosa of mice and rats. Cancer Res. 47: 4150- 4159.
    • (1987) Cancer Res , vol.47 , pp. 4150-4159
    • Gillner, M.1
  • 21
    • 3142781649 scopus 로고    scopus 로고
    • Association of pesticide exposure with neurologic dysfunction and disease
    • Kamel, F. & J.A. Hoppin. 2004. Association of pesticide exposure with neurologic dysfunction and disease. Environ. Health Perspect. 112: 950-958.
    • (2004) Environ. Health Perspect , vol.112 , pp. 950-958
    • Kamel, F.1    Hoppin, J.A.2
  • 22
    • 0027378820 scopus 로고    scopus 로고
    • McLean, J.H. et al. 1993. Selective lesions of neural pathways following viral inoculation of the olfactory bulb. Exp. Neurol. 122: 209-222. 22a.Zanusso, G. et al. 2009. Different prion conformers target the olfactory pathway in sporadic Creutzfeldt- Jakob disease. Ann. N. Y. Acad. Sci. International Symposium on Olfaction and Taste. 1170: 637-643.
    • McLean, J.H. et al. 1993. Selective lesions of neural pathways following viral inoculation of the olfactory bulb. Exp. Neurol. 122: 209-222. 22a.Zanusso, G. et al. 2009. Different prion conformers target the olfactory pathway in sporadic Creutzfeldt- Jakob disease. Ann. N. Y. Acad. Sci. International Symposium on Olfaction and Taste. 1170: 637-643.
  • 23
    • 0037456356 scopus 로고    scopus 로고
    • Detection of pathologic prion protein in the olfactory epithelium in sporadic Creutzfeldt-Jakob disease
    • Zanusso, G. et al. 2003. Detection of pathologic prion protein in the olfactory epithelium in sporadic Creutzfeldt-Jakob disease. N. Engl. J. Med. 348: 711- 719.
    • (2003) N. Engl. J. Med , vol.348 , pp. 711-719
    • Zanusso, G.1
  • 24
    • 0034880896 scopus 로고    scopus 로고
    • New variant Creutzfeldt- Jakob disease presenting with loss of taste and smell
    • Reuber, M. et al. 2001. New variant Creutzfeldt- Jakob disease presenting with loss of taste and smell. J. Neurol. Neurosurg. Psychiatry 71: 412-413.
    • (2001) J. Neurol. Neurosurg. Psychiatry , vol.71 , pp. 412-413
    • Reuber, M.1
  • 25
    • 0141750206 scopus 로고    scopus 로고
    • Odor perception in neurodegenerative diseases
    • 2nd ed. R.L. Doty, Ed, Marcel Dekker. New York, NY
    • Doty, R.L. 2003. Odor perception in neurodegenerative diseases. In Handbook of Olfaction and Gustation, 2nd ed. R.L. Doty, Ed.: 479-502. Marcel Dekker. New York, NY.
    • (2003) Handbook of Olfaction and Gustation , pp. 479-502
    • Doty, R.L.1
  • 26
    • 0023765129 scopus 로고
    • Olfactory dysfunction in parkinsonism: A general deficit unrelated to neurologic signs, disease stage, or disease duration
    • Doty, R.L., D.A. Deems & S. Stellar. 1988. Olfactory dysfunction in parkinsonism: a general deficit unrelated to neurologic signs, disease stage, or disease duration. Neurology 38: 1237-1244.
    • (1988) Neurology , vol.38 , pp. 1237-1244
    • Doty, R.L.1    Deems, D.A.2    Stellar, S.3
  • 27
    • 0000954482 scopus 로고    scopus 로고
    • Impaired olfaction as a marker for cognitive decline: Interaction with apolipoprotein E ε4 status
    • Graves, A.B. et al. 1999. Impaired olfaction as a marker for cognitive decline: interaction with apolipoprotein E ε4 status. Neurology 53: 1480-1487.
    • (1999) Neurology , vol.53 , pp. 1480-1487
    • Graves, A.B.1
  • 28
    • 3843078591 scopus 로고    scopus 로고
    • Idiopathic hyposmia as a preclinical sign of Parkinson's disease
    • Ponsen, M.M. et al. 2004. Idiopathic hyposmia as a preclinical sign of Parkinson's disease. Ann. Neurol. 56:173-181.
    • (2004) Ann. Neurol , vol.56 , pp. 173-181
    • Ponsen, M.M.1
  • 29
    • 0034961813 scopus 로고    scopus 로고
    • Subclinical dopaminergic dysfunction in asymptomatic Parkinson's disease patients' relatives with a decreased sense of smell
    • Berendse,H.W. et al. 2001. Subclinical dopaminergic dysfunction in asymptomatic Parkinson's disease patients' relatives with a decreased sense of smell. Ann. Neurol. 50: 34-41.
    • (2001) Ann. Neurol , vol.50 , pp. 34-41
    • Berendse, H.W.1
  • 30
    • 0029031709 scopus 로고
    • The anterior olfactory nucleus in Parkinson's disease
    • Pearce, R.K., C.H. Hawkes & S.E. Daniel. 1995. The anterior olfactory nucleus in Parkinson's disease. Movement Disord. 10: 283-287.
    • (1995) Movement Disord , vol.10 , pp. 283-287
    • Pearce, R.K.1    Hawkes, C.H.2    Daniel, S.E.3
  • 31
    • 0023178399 scopus 로고
    • Olfactory bulb changes in Alzheimer's disease
    • Ohm,T.G. & H. Braak. 1987. Olfactory bulb changes in Alzheimer's disease. Acta Neuropathol. 73: 365- 369.
    • (1987) Acta Neuropathol , vol.73 , pp. 365-369
    • Ohm, T.G.1    Braak, H.2
  • 32
    • 33751312830 scopus 로고    scopus 로고
    • Olfactory tau pathology in Alzheimer disease and mild cognitive impairment
    • Attems, J. & K.A. Jellinger. 2006. Olfactory tau pathology in Alzheimer disease and mild cognitive impairment. Clin. Neuropathol. 25: 265-271.
    • (2006) Clin. Neuropathol , vol.25 , pp. 265-271
    • Attems, J.1    Jellinger, K.A.2
  • 33
    • 0035847617 scopus 로고    scopus 로고
    • Olfactory centres in Alzheimer's disease: Olfactory bulb is involved in early Braak's stages
    • Kovacs, T., N.J. Cairns & P.L. Lantos. 2001. Olfactory centres in Alzheimer's disease: olfactory bulb is involved in early Braak's stages. Neuroreport 12: 285- 288.
    • (2001) Neuroreport , vol.12 , pp. 285-288
    • Kovacs, T.1    Cairns, N.J.2    Lantos, P.L.3
  • 34
    • 0030222337 scopus 로고    scopus 로고
    • Manganese and copper-zinc superoxide dismutases in the human olfactory mucosa: Increased immunoreactivity in Alzheimer's disease
    • Kulkarni-Narla, A. et al. 1996. Manganese and copper-zinc superoxide dismutases in the human olfactory mucosa: increased immunoreactivity in Alzheimer's disease. Exp. Neurol. 140: 115-125.
    • (1996) Exp. Neurol , vol.140 , pp. 115-125
    • Kulkarni-Narla, A.1
  • 35
    • 0038748401 scopus 로고    scopus 로고
    • Braak, H. et al. 2003. Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen. J. Neural Transm. 110: 517-536. 35a.Hawkes, C.H., K. Del Tredici & H. Braak. 2009. Parkinson's disease: the dual hit theory revisited. Ann. N. Y. Acad. Sci. International Symposium on Olfaction and Taste. 1170: 615-622.
    • Braak, H. et al. 2003. Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen. J. Neural Transm. 110: 517-536. 35a.Hawkes, C.H., K. Del Tredici & H. Braak. 2009. Parkinson's disease: the dual hit theory revisited. Ann. N. Y. Acad. Sci. International Symposium on Olfaction and Taste. 1170: 615-622.
  • 37
    • 0026697838 scopus 로고
    • Lack of olfactory dysfunction in MPTP-induced parkinsonism
    • Doty, R.L. et al. 1992. Lack of olfactory dysfunction in MPTP-induced parkinsonism. Ann. Neurol. 32: 97- 100.
    • (1992) Ann. Neurol , vol.32 , pp. 97-100
    • Doty, R.L.1
  • 38
    • 0032829070 scopus 로고    scopus 로고
    • Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine exposure
    • Langston, J.W. et al. 1999. Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine exposure. Ann. Neurol. 46: 598-605.
    • (1999) Ann. Neurol , vol.46 , pp. 598-605
    • Langston, J.W.1
  • 39
    • 33749022060 scopus 로고    scopus 로고
    • Ross, G.W. et al. 2006. Association of olfactory dysfunction with incidental Lewy bodies. Movement Disord.21: 2062-2067. 39a. Prediger, R.D.S. et al. 2009. The risk is in the air: an intranasal MPTP rat model of Parkinson's disease. Ann. N. Y. Acad. Sci. International Symposium on Olfaction and Taste. 1170: 629-636.
    • Ross, G.W. et al. 2006. Association of olfactory dysfunction with incidental Lewy bodies. Movement Disord.21: 2062-2067. 39a. Prediger, R.D.S. et al. 2009. The risk is in the air: an intranasal MPTP rat model of Parkinson's disease. Ann. N. Y. Acad. Sci. International Symposium on Olfaction and Taste. 1170: 629-636.
  • 40
    • 33750619116 scopus 로고    scopus 로고
    • The risk is in the air: Intranasal administration of MPTP to rats reproducing clinical features of Parkinson's disease
    • Prediger, R.D. S. et al. 2006. The risk is in the air: intranasal administration of MPTP to rats reproducing clinical features of Parkinson's disease. Exp. Neurol.202: 391-403.
    • (2006) Exp. Neurol , vol.202 , pp. 391-403
    • Prediger, R.D.S.1
  • 41
    • 0027972113 scopus 로고
    • Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine. 1. Systemic administration
    • Giovanni, A. et al. 1994. Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine. 1. Systemic administration. J. Pharmacol. Exp. Ther. 270: 1000-1007.
    • (1994) J. Pharmacol. Exp. Ther , vol.270 , pp. 1000-1007
    • Giovanni, A.1
  • 42
    • 0027986482 scopus 로고
    • Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine.2. Central administration of 1-methyl- 4-phenylpyridinium
    • Giovanni, A., P.K. Sonsalla & R.E. Heikkila. 1994. Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine.2. Central administration of 1-methyl- 4-phenylpyridinium. J. Pharmacol. Exp. Ther. 270:1008-1014.
    • (1994) J. Pharmacol. Exp. Ther , vol.270 , pp. 1008-1014
    • Giovanni, A.1    Sonsalla, P.K.2    Heikkila, R.E.3
  • 43
    • 0036001304 scopus 로고    scopus 로고
    • Air pollution and brain damage
    • Calderon-Garciduenas, L. et al. 2002. Air pollution and brain damage. Toxicol. Pathol. 30: 373- 389.
    • (2002) Toxicol. Pathol , vol.30 , pp. 373-389
    • Calderon-Garciduenas, L.1
  • 44
    • 48249114740 scopus 로고    scopus 로고
    • Detection of Huntington's disease decades before diagnosis: The predict-HD study
    • Paulsen, J.S. et al. 2008. Detection of Huntington's disease decades before diagnosis: the predict-HD study. J. Neurol. Neurosurg. Psychiatry 79: 874-880.
    • (2008) J. Neurol. Neurosurg. Psychiatry , vol.79 , pp. 874-880
    • Paulsen, J.S.1
  • 45
    • 0026670071 scopus 로고
    • Neuropathologic features of Parkinsons, Huntingtons, and Alzheimers diseases
    • Forno, L.S. 1992. Neuropathologic features of Parkinsons, Huntingtons, and Alzheimers diseases. Ann. N. Y. Acad. Sci. 648: 6-16.
    • (1992) Ann. N. Y. Acad. Sci , vol.648 , pp. 6-16
    • Forno, L.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.