Analysis of Fuzhisan and quantitation of baicalin and ginsenoside Rb 1 by HPLC-DAD-ELSD

Archives of Pharmacal Research

Volumn 32, Issue 7, 2009, Pages 989-996

  Zhao, Jingkun ^a   Wang, Desheng ^a   Duan, Shurong ^a   Wang, Jianxiu ^a   Bai, Jing ^b   Li, Wenlan ^b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b HARBIN UNIVERSITY OF COMMERCE   (China)

Author keywords

Chromatographic fingerprints; Fuzhisan preparations; Quality control; Traditional Chinese medicine

Indexed keywords

ACETONITRILE; ANEMONE ALTAICA EXTRACT; ANGELICA SINENSIS EXTRACT; BAICALIN; FERULIC ACID; FUZHISAN; GINSENOSIDE RB 1; GINSENOSIDE RE; GINSENOSIDE RG 1; HERBACEOUS AGENT; PLANT EXTRACT; SCUTELLARIA BAICALENSIS EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; COLUMN CHROMATOGRAPHY; DRUG QUALITY; DRUG SCREENING; GINSENG; HERBAL MEDICINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIGHT SCATTERING; NONHUMAN; SCUTELLARIA BAICALENSIS; TEMPERATURE;

CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; FLAVONOIDS; GINSENOSIDES; LIGHT; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; SCATTERING, RADIATION;

EID: 68649115569     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-009-1703-2     Document Type: Article

References (24)

1. J. Cao Y. Xu Y. H. Zhang 2004 Fingerprint Chromatogram by High Performance Liquid Chromatography with Evaporative Light Scattering Detection of QingKaiLing Injection and Its Relationship with Quality Control J. Anal. Chem. 32 469 473
2. X. Y. Chai S. L. Li P. Li 2005 Quality evaluation of Flos lonicerae through a simultaneous determination of seven saponins by HPLC with ELSD J. Chromatogr. A. 1070 43 48
3. C. Y. Chen L. W. Qi H. J. Li 2007 Simultaneous determination of iridoids, phenolic acids, flavonoids, and saponins in Flos Lonicerae and Flos Lonicerae Japonicae by HPLCDAD-ELSD coupled with principal component analysis J. Sep. Sci. 30 3181 3192
4. P. Drasar J. Moravcova 2004 Recent advances in analysis of Chinese medical plants and traditional medicines J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 812 3 21
5. Drug Administration Bureau of China, Requirements for Studying Fingerprints of Traditional Chinese Medicine Injections, 3-5 (2000).
6. P.T. Francis A. M. Palmer M. Snape 1999 The cholinergic hypothesis of Alzheimer's disease: a review of progress J. Neurol. Neurosurg. Psych. 66 137 147
7. B. Z. Gang D. S. Wang C. L. Wang 2005 The efficacy of Fuzhisan in patients with Alzheimer's disease Chin. J. Apoplexy Nerv. Dis. 22 527 529
8. S. L. Li R. W. Jiang P. M. Hon 2007 Quality evaluation of Radix Stemonae through simultaneous quantification of bioactive alkaloids by high-performance liquid chromatography coupled with diode array and evaporative light scattering detectors Biomed. Chromatogr. 21 1088 1094
9. X. L. Li D. S. Wang B. Q. Zhao 2008 Effects of Chinese Herbal Medicine Fuzhisan on aged rats Exp. Gerontol. 43 853 859
10. L. W. Qi Q. T. Yu P. Li 2006 Quality evaluation of Radix Astragali through a simultaneous determination of six major active isoflavonoids and four main saponins by high-performance liquid chromatography coupled with diode array and evaporative light scattering detectors J. Chromatogr. A. 1134 162 169
11. Qi, L. W., Li, P., and Ren, M. T., Application of high-performance liquid chromatography-electrospray ionization time-of-flight mass spectrometry for analysis and quality control of Radix Astragali and its preparations. J. Chromatogr. A., doi:10.1016/j.chroma.2008.02.095 (2008).
12. Q. Shao Y. Y. Cheng 2006 Fingerprinting Analysis of the Extracts of Compound Danshen by High Performance Liquid Chromatography with Ultraviolet and Evaporative Light Scattering Detection J. Anal. Chem. 34 863 866
13. The State Pharmacopoeia Commission of China. Pharmacopoeia of the People's Republic of China, Chemical Industry Publishers, Beijing, China, 105 (2005).
14. J. Travis 2005 Saving the mind faces high hurdles Science. 309 731
15. T. A. van Beek F. W. Claassen J. Dorado 2007 Fungal biotransformation products of dehydroabietic acid J. Nat. Prod. 70 154 159
16. A. M. van Nederkassel V. Vijverman D. L. Massart 2005 Development of a ginkgo biloba fingerprint chromatogram with UV and evaporative light scattering detection and optimization of the evaporative light scattering detector operating conditions J. Chromatogr. A. 1085 230 239
17. D. S. Wang X. Y. Xu S. R. Wen 1998 Experimental and clinical study on treatment of Alzheimer's disease with Fuzhisan, nimodipine and ganglioside Chin. Inform. TCMs. 6 12 14
18. Y. J. Wei L. W. Qi P. Li 2007 Improved quality control method for Fufang Danshen preparations through simultaneous determination of phenolic acids, saponins and diterpenoid quinones by HPLC coupled with diode array and evaporative light scattering detectors J. Pharm. Biomed. Anal. 45 775 784
19. S. R. Wen D. S. Wang J. Y. Zhang 2003 Study of Fuzhisan against A-25-35 toxicity to nerve cells Chin. J. Apoplexy Nerv. Dis. 20 431 433
20. S. R. Wen D. S. Wang J.Y. Zhang 2005 Effect of Fuzhisan on the area of neurosome and the length of axon Chin. J. Clin. Rehabil. 9 241 243
21. S. R. Wen D. S. Wang J.Y. Zhang 2005 Effect and mechanism of fuzhisan on toxic reaction of amyloid beta 25-35 to neural cells Chin. J. Clin. Rehabil. 9 248 250
22. World Health Organization. Guidelines for the Assessment of Herbal Medicines. WHO Geneva (1991).
23. Q. T. Yu L.W. Qi P. Li 2007 Determination of seventeen main flavonoids and saponins in the medicinal plant Huang-qi (Radix astragali) by HPLC-DAD-ELSD J. Sep. Sci. 30 1292 1299
24. J. K. Zhao D. S. Wang S. R. Duan 2007 Fingerprinting of Fuzhisan by high-performance liquid chromatography with ultraviolet and evaporative light scattering detector Nan Fang Yi Ke Da Xue Xue Bao. 27 1830 1833