-
1
-
-
3242707674
-
Intracellular antibodies as specific reagents for functional ablation: future therapeutic molecules
-
Lobato M.N., and Rabbitts T.H. Intracellular antibodies as specific reagents for functional ablation: future therapeutic molecules. Curr. Mol. Med. 4 (2004) 519-528
-
(2004)
Curr. Mol. Med.
, vol.4
, pp. 519-528
-
-
Lobato, M.N.1
Rabbitts, T.H.2
-
2
-
-
0141741347
-
Parkinson's disease: mechanisms and models
-
Dauer W., and Przedborski S. Parkinson's disease: mechanisms and models. Neuron 39 (2003) 889-909
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
3
-
-
0029414766
-
Nigral and extranigral pathology in Parkinson's disease
-
Braak H., Braak E., Yilmazer D., Schultz C., de Vos R.A., and Jansen E.N. Nigral and extranigral pathology in Parkinson's disease. J. Neural Transm. (Suppl. 46) (1995) 15-31
-
(1995)
J. Neural Transm. (Suppl.
, vol.46
, pp. 15-31
-
-
Braak, H.1
Braak, E.2
Yilmazer, D.3
Schultz, C.4
de Vos, R.A.5
Jansen, E.N.6
-
4
-
-
0030882856
-
α-Synuclein in Lewy bodies
-
Spillantini M.G., Schmidt M.L., Lee V.M.Y., Trojanowski J.Q., Roos J., and Goedert M. α-Synuclein in Lewy bodies. Nature 388 (1997) 839-840
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.Y.3
Trojanowski, J.Q.4
Roos, J.5
Goedert, M.6
-
5
-
-
3142523288
-
Genetic clues to the pathogenesis of Parkinson's disease
-
Vila M., and Przedborski S. Genetic clues to the pathogenesis of Parkinson's disease. Nat. Med. 10 Suppl (2004) S58-S62
-
(2004)
Nat. Med.
, vol.10
, Issue.SUPPL
-
-
Vila, M.1
Przedborski, S.2
-
6
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
Kohler G., and Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256 (1975) 495-497
-
(1975)
Nature
, vol.256
, pp. 495-497
-
-
Kohler, G.1
Milstein, C.2
-
7
-
-
0020031557
-
Treatment of B-cell lymphoma with monoclonal anti-idiotype antibody
-
Miller R.A., Maloney D.G., Warnke R., and Levy R. Treatment of B-cell lymphoma with monoclonal anti-idiotype antibody. N. Engl. J. Med. 306 (1982) 517-522
-
(1982)
N. Engl. J. Med.
, vol.306
, pp. 517-522
-
-
Miller, R.A.1
Maloney, D.G.2
Warnke, R.3
Levy, R.4
-
9
-
-
0028291823
-
Isolation of high affinity human antibodies directly from large synthetic repertoires
-
Griffiths A.D., Williams S.C., Hartley O., Tomlinson I.M., Waterhouse P., Crosby W.L., Kontermann R.E., Jones P.T., Low N.M., and Allison T.J. Isolation of high affinity human antibodies directly from large synthetic repertoires. EMBO J. 13 (1994) 3245-3260
-
(1994)
EMBO J.
, vol.13
, pp. 3245-3260
-
-
Griffiths, A.D.1
Williams, S.C.2
Hartley, O.3
Tomlinson, I.M.4
Waterhouse, P.5
Crosby, W.L.6
Kontermann, R.E.7
Jones, P.T.8
Low, N.M.9
Allison, T.J.10
-
11
-
-
0037318058
-
Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library
-
Feldhaus M.J., Siegel R.W., Opresko L.K., Coleman J.R., Feldhaus J.M., Yeung Y.A., Cochran J.R., Heinzelman P., Colby D., Swers J., Graff C., Wiley H.S., and Wittrup K.D. Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library. Nat. Biotechnol. 21 (2003) 163-170
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 163-170
-
-
Feldhaus, M.J.1
Siegel, R.W.2
Opresko, L.K.3
Coleman, J.R.4
Feldhaus, J.M.5
Yeung, Y.A.6
Cochran, J.R.7
Heinzelman, P.8
Colby, D.9
Swers, J.10
Graff, C.11
Wiley, H.S.12
Wittrup, K.D.13
-
12
-
-
0030974119
-
In vitro selection and evolution of functional proteins by using ribosome display
-
Hanes J., and Pluckthun A. In vitro selection and evolution of functional proteins by using ribosome display. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 4937-4942
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 4937-4942
-
-
Hanes, J.1
Pluckthun, A.2
-
13
-
-
0032797898
-
Development of an optimized expression system for the screening of antibody libraries displayed on the Escherichia coli surface
-
Daugherty P.S., Olsen M.J., Iverson B.L., and Georgiou G. Development of an optimized expression system for the screening of antibody libraries displayed on the Escherichia coli surface. Protein Eng. 12 (1999) 613-621
-
(1999)
Protein Eng.
, vol.12
, pp. 613-621
-
-
Daugherty, P.S.1
Olsen, M.J.2
Iverson, B.L.3
Georgiou, G.4
-
14
-
-
0035014528
-
Isolation of high-affinity ligand-binding proteins by periplasmic expression with cytometric screening (PECS)
-
Chen G., Hayhurst A., Thomas J.G., Harvey B.R., Iverson B.L., and Georgiou G. Isolation of high-affinity ligand-binding proteins by periplasmic expression with cytometric screening (PECS). Nat. Biotechnol. 19 (2001) 537-542
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 537-542
-
-
Chen, G.1
Hayhurst, A.2
Thomas, J.G.3
Harvey, B.R.4
Iverson, B.L.5
Georgiou, G.6
-
15
-
-
0035462330
-
Recombinant antibodies for cancer diagnosis and therapy
-
Hudson P.J., and Souriau C. Recombinant antibodies for cancer diagnosis and therapy. Expert. Opin. Biol. Ther. 1 (2001) 845-855
-
(2001)
Expert. Opin. Biol. Ther.
, vol.1
, pp. 845-855
-
-
Hudson, P.J.1
Souriau, C.2
-
16
-
-
9544250404
-
Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library
-
Begent R.H., Verhaar M.J., Chester K.A., Casey J.L., Green A.J., Napier M.P., Hope-Stone L.D., Cushen N., Keep P.A., Johnson C.J., Hawkins R.E., Hilson A.J., and Robson L. Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library. Nat. Med. 2 (1996) 979-984
-
(1996)
Nat. Med.
, vol.2
, pp. 979-984
-
-
Begent, R.H.1
Verhaar, M.J.2
Chester, K.A.3
Casey, J.L.4
Green, A.J.5
Napier, M.P.6
Hope-Stone, L.D.7
Cushen, N.8
Keep, P.A.9
Johnson, C.J.10
Hawkins, R.E.11
Hilson, A.J.12
Robson, L.13
-
17
-
-
38849143822
-
Biodistribution and tumor imaging of an anti-CEA single-chain antibody-albumin fusion protein
-
Yazaki P.J., Kassa T., Cheung C.W., Crow D.M., Sherman M.A., Bading J.R., Anderson A.L., Colcher D., and Raubitschek A. Biodistribution and tumor imaging of an anti-CEA single-chain antibody-albumin fusion protein. Nucl. Med. Biol. 35 (2008) 151-158
-
(2008)
Nucl. Med. Biol.
, vol.35
, pp. 151-158
-
-
Yazaki, P.J.1
Kassa, T.2
Cheung, C.W.3
Crow, D.M.4
Sherman, M.A.5
Bading, J.R.6
Anderson, A.L.7
Colcher, D.8
Raubitschek, A.9
-
18
-
-
21344437728
-
Optimizing radiolabeled engineered anti-p185HER2 antibody fragments for in vivo imaging
-
Olafsen T., Kenanova V.E., Sundaresan G., Anderson A.L., Crow D., Yazaki P.J., Li L., Press M.F., Gambhir S.S., Williams L.E., Wong J.Y., Raubitschek A.A., Shively J.E., and Wu A.M. Optimizing radiolabeled engineered anti-p185HER2 antibody fragments for in vivo imaging. Cancer Res. 65 (2005) 5907-5916
-
(2005)
Cancer Res.
, vol.65
, pp. 5907-5916
-
-
Olafsen, T.1
Kenanova, V.E.2
Sundaresan, G.3
Anderson, A.L.4
Crow, D.5
Yazaki, P.J.6
Li, L.7
Press, M.F.8
Gambhir, S.S.9
Williams, L.E.10
Wong, J.Y.11
Raubitschek, A.A.12
Shively, J.E.13
Wu, A.M.14
-
19
-
-
0004198722
-
Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli
-
Huston J.S., Levinson D., Mudgett-Hunter M., Tai M.S., Novotny J., Margolies M.N., Ridge R.J., Bruccoleri R.E., Haber E., and Crea R. Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli. Proc. Natl. Acad. Sci. U. S. A. 85 (1988) 5879-5883
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 5879-5883
-
-
Huston, J.S.1
Levinson, D.2
Mudgett-Hunter, M.3
Tai, M.S.4
Novotny, J.5
Margolies, M.N.6
Ridge, R.J.7
Bruccoleri, R.E.8
Haber, E.9
Crea, R.10
-
20
-
-
0026317443
-
By-passing immunization. Human antibodies from V-gene libraries displayed on phage
-
Marks J.D., Hoogenboom H.R., Bonnert T.P., McCafferty J., Griffiths A.D., and Winter G. By-passing immunization. Human antibodies from V-gene libraries displayed on phage. J. Mol. Biol. 222 (1991) 581-597
-
(1991)
J. Mol. Biol.
, vol.222
, pp. 581-597
-
-
Marks, J.D.1
Hoogenboom, H.R.2
Bonnert, T.P.3
McCafferty, J.4
Griffiths, A.D.5
Winter, G.6
-
21
-
-
0033506131
-
Generating improved single-chain Fv molecules for tumor targeting
-
Adams G.P., and Schier R. Generating improved single-chain Fv molecules for tumor targeting. J. Immunol. Methods 231 (1999) 249-260
-
(1999)
J. Immunol. Methods
, vol.231
, pp. 249-260
-
-
Adams, G.P.1
Schier, R.2
-
22
-
-
0032718607
-
Intrabody construction and expression III: engineering hyperstable V(H) domains
-
Wirtz P., and Steipe B. Intrabody construction and expression III: engineering hyperstable V(H) domains. Protein Sci. 8 (1999) 2245-2250
-
(1999)
Protein Sci.
, vol.8
, pp. 2245-2250
-
-
Wirtz, P.1
Steipe, B.2
-
23
-
-
0033538557
-
Removal of the conserved disulfide bridges from the scFv fragment of an antibody: effects on folding kinetics and aggregation
-
Ramm K., Gehrig P., and Pluckthun A. Removal of the conserved disulfide bridges from the scFv fragment of an antibody: effects on folding kinetics and aggregation. J. Mol. Biol. 290 (1999) 535-546
-
(1999)
J. Mol. Biol.
, vol.290
, pp. 535-546
-
-
Ramm, K.1
Gehrig, P.2
Pluckthun, A.3
-
24
-
-
0035793208
-
Stability engineering of antibody single-chain Fv fragments
-
Worn A., and Pluckthun A. Stability engineering of antibody single-chain Fv fragments. J. Mol. Biol. 305 (2001) 989-1010
-
(2001)
J. Mol. Biol.
, vol.305
, pp. 989-1010
-
-
Worn, A.1
Pluckthun, A.2
-
25
-
-
10344257196
-
A human single-chain Fv intrabody blocks aberrant cellular effects of overexpressed alpha-synuclein
-
Zhou C., Emadi S., Sierks M.R., and Messer A. A human single-chain Fv intrabody blocks aberrant cellular effects of overexpressed alpha-synuclein. Mol. Ther. 10 (2004) 1023-1031
-
(2004)
Mol. Ther.
, vol.10
, pp. 1023-1031
-
-
Zhou, C.1
Emadi, S.2
Sierks, M.R.3
Messer, A.4
-
26
-
-
39649109675
-
An scFv intrabody against the nonamyloid component of alpha-synuclein reduces intracellular aggregation and toxicity
-
Lynch S.M., Zhou C., and Messer A. An scFv intrabody against the nonamyloid component of alpha-synuclein reduces intracellular aggregation and toxicity. J. Mol. Biol. 377 (2008) 136-147
-
(2008)
J. Mol. Biol.
, vol.377
, pp. 136-147
-
-
Lynch, S.M.1
Zhou, C.2
Messer, A.3
-
27
-
-
0032716364
-
Selection of antibodies for intracellular function using a two-hybrid in vivo system
-
Visintin M., Tse E., Axelson H., Rabbitts T.H., and Cattaneo A. Selection of antibodies for intracellular function using a two-hybrid in vivo system. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 11723-11728
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 11723-11728
-
-
Visintin, M.1
Tse, E.2
Axelson, H.3
Rabbitts, T.H.4
Cattaneo, A.5
-
28
-
-
0343527530
-
In vivo selection of single-chain antibodies using a yeast two-hybrid system
-
Portner-Taliana A., Russell M., Froning K.J., Budworth P.R., Comiskey J.D., and Hoeffler J.P. In vivo selection of single-chain antibodies using a yeast two-hybrid system. J. Immunol. Methods 238 (2000) 161-172
-
(2000)
J. Immunol. Methods
, vol.238
, pp. 161-172
-
-
Portner-Taliana, A.1
Russell, M.2
Froning, K.J.3
Budworth, P.R.4
Comiskey, J.D.5
Hoeffler, J.P.6
-
29
-
-
0033968453
-
Analysis of the interaction between single-chain variable fragments and their antigen in a reducing intracellular environment using the two-hybrid system
-
De J.G., Fiers E., Eeckhout D., and Depicker A. Analysis of the interaction between single-chain variable fragments and their antigen in a reducing intracellular environment using the two-hybrid system. FEBS Lett. 467 (2000) 316-320
-
(2000)
FEBS Lett.
, vol.467
, pp. 316-320
-
-
De, J.G.1
Fiers, E.2
Eeckhout, D.3
Depicker, A.4
-
30
-
-
0038423087
-
Correlation between in vitro stability and in vivo performance of anti-GCN4 intrabodies as cytoplasmic inhibitors
-
Worn A., uf der M.A., Escher D., Honegger A., Barberis A., and Pluckthun A. Correlation between in vitro stability and in vivo performance of anti-GCN4 intrabodies as cytoplasmic inhibitors. J. Biol. Chem. 275 (2000) 2795-2803
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2795-2803
-
-
Worn, A.1
uf der, M.A.2
Escher, D.3
Honegger, A.4
Barberis, A.5
Pluckthun, A.6
-
31
-
-
0024022171
-
A new means of inducibly inactivating a cellular protein
-
Carlson J.R. A new means of inducibly inactivating a cellular protein. Mol. Cell Biol. 8 (1988) 2638-2646
-
(1988)
Mol. Cell Biol.
, vol.8
, pp. 2638-2646
-
-
Carlson, J.R.1
-
32
-
-
0037449785
-
Inhibition of Tat-mediated transactivation and HIV-1 replication by human anti-hCyclinT1 intrabodies
-
Bai J., Sui J., Zhu R.Y., Tallarico A.S., Gennari F., Zhang D., and Marasco W.A. Inhibition of Tat-mediated transactivation and HIV-1 replication by human anti-hCyclinT1 intrabodies. J. Biol. Chem. 278 (2003) 1433-1442
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1433-1442
-
-
Bai, J.1
Sui, J.2
Zhu, R.Y.3
Tallarico, A.S.4
Gennari, F.5
Zhang, D.6
Marasco, W.A.7
-
33
-
-
0032771488
-
The selection of intracellular antibodies
-
Cattaneo A., and Biocca S. The selection of intracellular antibodies. Trends Biotechnol. 17 (1999) 115-121
-
(1999)
Trends Biotechnol.
, vol.17
, pp. 115-121
-
-
Cattaneo, A.1
Biocca, S.2
-
34
-
-
0028997906
-
Intracellular immunization: antibody targeting to subcellular compartments
-
Biocca S., and Cattaneo A. Intracellular immunization: antibody targeting to subcellular compartments. Trends Cell Biol. 5 (1995) 248-252
-
(1995)
Trends Cell Biol.
, vol.5
, pp. 248-252
-
-
Biocca, S.1
Cattaneo, A.2
-
35
-
-
0027275371
-
Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody
-
Marasco W.A., Haseltine W.A., and Chen S.Y. Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody. Proc. Natl. Acad. Sci. U. S. A. 90 (1993) 7889-7893
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 7889-7893
-
-
Marasco, W.A.1
Haseltine, W.A.2
Chen, S.Y.3
-
36
-
-
0005382256
-
Restoration of transcriptional activity of p53 mutants in human tumour cells by intracellular expression of anti-p53 single chain Fv fragments
-
Caron de F.C., Gruel N., Venot C., Debussche L., Conseiller E., Dureuil C., Teillaud J.L., Tocque B., and Bracco L. Restoration of transcriptional activity of p53 mutants in human tumour cells by intracellular expression of anti-p53 single chain Fv fragments. Oncogene 18 (1999) 551-557
-
(1999)
Oncogene
, vol.18
, pp. 551-557
-
-
Caron de, F.C.1
Gruel, N.2
Venot, C.3
Debussche, L.4
Conseiller, E.5
Dureuil, C.6
Teillaud, J.L.7
Tocque, B.8
Bracco, L.9
-
37
-
-
0032521206
-
Intracellular expression of an antibody fragment-neutralizing p21 ras promotes tumor regression
-
Cochet O., Kenigsberg M., Delumeau I., Virone-Oddos A., Multon M.C., Fridman W.H., Schweighoffer F., Teillaud J.L., and Tocque B. Intracellular expression of an antibody fragment-neutralizing p21 ras promotes tumor regression. Cancer Res. 58 (1998) 1170-1176
-
(1998)
Cancer Res.
, vol.58
, pp. 1170-1176
-
-
Cochet, O.1
Kenigsberg, M.2
Delumeau, I.3
Virone-Oddos, A.4
Multon, M.C.5
Fridman, W.H.6
Schweighoffer, F.7
Teillaud, J.L.8
Tocque, B.9
-
38
-
-
13444249481
-
Targeting tumor angiogenesis with adenovirus-delivered anti-Tie-2 intrabody
-
Popkov M., Jendreyko N., McGavern D.B., Rader C., and Barbas III C.F. Targeting tumor angiogenesis with adenovirus-delivered anti-Tie-2 intrabody. Cancer Res. 65 (2005) 972-981
-
(2005)
Cancer Res.
, vol.65
, pp. 972-981
-
-
Popkov, M.1
Jendreyko, N.2
McGavern, D.B.3
Rader, C.4
Barbas III, C.F.5
-
39
-
-
44649113841
-
Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin
-
Wang C.E., Zhou H., McGuire J.R., Cerullo V., Lee B., Li S.H., and Li X.J. Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin. J. Cell Biol. 181 (2008) 803-816
-
(2008)
J. Cell Biol.
, vol.181
, pp. 803-816
-
-
Wang, C.E.1
Zhou, H.2
McGuire, J.R.3
Cerullo, V.4
Lee, B.5
Li, S.H.6
Li, X.J.7
-
40
-
-
0028839655
-
Targeted tumor killing via an intracellular antibody against erbB-2
-
Deshane J., Siegal G.P., Alvarez R.D., Wang M.H., Feng M., Cabrera G., Liu T., Kay M., and Curiel D.T. Targeted tumor killing via an intracellular antibody against erbB-2. J. Clin. Invest 96 (1995) 2980-2989
-
(1995)
J. Clin. Invest
, vol.96
, pp. 2980-2989
-
-
Deshane, J.1
Siegal, G.P.2
Alvarez, R.D.3
Wang, M.H.4
Feng, M.5
Cabrera, G.6
Liu, T.7
Kay, M.8
Curiel, D.T.9
-
41
-
-
18544408628
-
A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): a phase I trial
-
Alvarez R.D., Barnes M.N., Gomez-Navarro J., Wang M., Strong T.V., Arafat W., Arani R.B., Johnson M.R., Roberts B.L., Siegal G.P., and Curiel D.T. A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): a phase I trial. Clin. Cancer Res. 6 (2000) 3081-3087
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3081-3087
-
-
Alvarez, R.D.1
Barnes, M.N.2
Gomez-Navarro, J.3
Wang, M.4
Strong, T.V.5
Arafat, W.6
Arani, R.B.7
Johnson, M.R.8
Roberts, B.L.9
Siegal, G.P.10
Curiel, D.T.11
-
42
-
-
0035836675
-
Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease
-
Lecerf J.M., Shirley T.L., Zhu Q., Kazantsev A., Amersdorfer P., Housman D.E., Messer A., and Huston J.S. Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 4764-4769
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 4764-4769
-
-
Lecerf, J.M.1
Shirley, T.L.2
Zhu, Q.3
Kazantsev, A.4
Amersdorfer, P.5
Housman, D.E.6
Messer, A.7
Huston, J.S.8
-
43
-
-
19944395483
-
Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody
-
Colby D.W., Chu Y., Cassady J.P., Duennwald M., Zazulak H., Webster J.M., Messer A., Lindquist S., Ingram V.M., and Wittrup K.D. Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 17616-17621
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 17616-17621
-
-
Colby, D.W.1
Chu, Y.2
Cassady, J.P.3
Duennwald, M.4
Zazulak, H.5
Webster, J.M.6
Messer, A.7
Lindquist, S.8
Ingram, V.M.9
Wittrup, K.D.10
-
44
-
-
23844543718
-
Suppression of Huntington's disease pathology in Drosophila by human single-chain Fv antibodies
-
Wolfgang W.J., Miller T.W., Webster J.M., Huston J.S., Thompson L.M., Marsh J.L., and Messer A. Suppression of Huntington's disease pathology in Drosophila by human single-chain Fv antibodies. Proc. Natl. Acad. Sci. U. S. A 102 (2005) 11563-11568
-
(2005)
Proc. Natl. Acad. Sci. U. S. A
, vol.102
, pp. 11563-11568
-
-
Wolfgang, W.J.1
Miller, T.W.2
Webster, J.M.3
Huston, J.S.4
Thompson, L.M.5
Marsh, J.L.6
Messer, A.7
-
45
-
-
15444374558
-
beta-Site specific intrabodies to decrease and prevent generation of Alzheimer's Abeta peptide
-
Paganetti P., Calanca V., Galli C., Stefani M., and Molinari M. beta-Site specific intrabodies to decrease and prevent generation of Alzheimer's Abeta peptide. J. Cell Biol. 168 (2005) 863-868
-
(2005)
J. Cell Biol.
, vol.168
, pp. 863-868
-
-
Paganetti, P.1
Calanca, V.2
Galli, C.3
Stefani, M.4
Molinari, M.5
-
46
-
-
0029904487
-
NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded
-
Weinreb P.H., Zhen W., Poon A.W., Conway K.A., and Lansbury Jr. P.T. NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded. Biochemistry 35 (1996) 13709-13715
-
(1996)
Biochemistry
, vol.35
, pp. 13709-13715
-
-
Weinreb, P.H.1
Zhen, W.2
Poon, A.W.3
Conway, K.A.4
Lansbury Jr., P.T.5
-
47
-
-
0035815115
-
Conformational properties of alpha-synuclein in its free and lipid-associated states
-
Eliezer D., Kutluay E., Bussell Jr. R., and Browne G. Conformational properties of alpha-synuclein in its free and lipid-associated states. J. Mol. Biol. 307 (2001) 1061-1073
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 1061-1073
-
-
Eliezer, D.1
Kutluay, E.2
Bussell Jr., R.3
Browne, G.4
-
48
-
-
0032573597
-
Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments
-
El-Agnaf O.M., Jakes R., Curran M.D., Middleton D., Ingenito R., Bianchi E., Pessi A., Neill D., and Wallace A. Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments. FEBS Lett. 440 (1998) 71-75
-
(1998)
FEBS Lett.
, vol.440
, pp. 71-75
-
-
El-Agnaf, O.M.1
Jakes, R.2
Curran, M.D.3
Middleton, D.4
Ingenito, R.5
Bianchi, E.6
Pessi, A.7
Neill, D.8
Wallace, A.9
-
49
-
-
0031787871
-
Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease
-
Conway K.A., Harper J.D., and Lansbury P.T. Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease. Nat. Med. 4 (1998) 1318-1320
-
(1998)
Nat. Med.
, vol.4
, pp. 1318-1320
-
-
Conway, K.A.1
Harper, J.D.2
Lansbury, P.T.3
-
50
-
-
0033583215
-
Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro
-
Giasson B.I., Uryu K., Trojanowski J.Q., and Lee V.M. Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro. J. Biol. Chem. 274 (1999) 7619-7622
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7619-7622
-
-
Giasson, B.I.1
Uryu, K.2
Trojanowski, J.Q.3
Lee, V.M.4
-
51
-
-
0032568534
-
α-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies
-
Spillantini M.G., Crowther R.A., Jakes R., Hasegawa M., and Goedert M. α-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 6469-6473
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
52
-
-
14644435825
-
Intrinsically unstructured proteins and their functions
-
Dyson H.J., and Wright P.E. Intrinsically unstructured proteins and their functions. Nat. Rev. Mol. Cell. Biol. 6 (2005) 197-208
-
(2005)
Nat. Rev. Mol. Cell. Biol.
, vol.6
, pp. 197-208
-
-
Dyson, H.J.1
Wright, P.E.2
-
53
-
-
0036128797
-
Natively unfolded proteins: a point where biology waits for physics
-
Uversky V.N. Natively unfolded proteins: a point where biology waits for physics. Protein Sci. 11 (2002) 739-756
-
(2002)
Protein Sci.
, vol.11
, pp. 739-756
-
-
Uversky, V.N.1
-
54
-
-
1542357652
-
Inhibiting aggregation of alpha-synuclein with human single chain antibody fragments
-
Emadi S., Liu R., Yuan B., Schulz P., McAllister C., Lyubchenko Y., Messer A., and Sierks M.R. Inhibiting aggregation of alpha-synuclein with human single chain antibody fragments. Biochemistry 43 (2004) 2871-2878
-
(2004)
Biochemistry
, vol.43
, pp. 2871-2878
-
-
Emadi, S.1
Liu, R.2
Yuan, B.3
Schulz, P.4
McAllister, C.5
Lyubchenko, Y.6
Messer, A.7
Sierks, M.R.8
-
55
-
-
33750291199
-
Isolating recombinant antibodies against specific protein morphologies using atomic force microscopy and phage display technologies
-
Barkhordarian H., Emadi S., Schulz P., and Sierks M.R. Isolating recombinant antibodies against specific protein morphologies using atomic force microscopy and phage display technologies. Protein Eng. Des. Sel. 19 (2006) 497-502
-
(2006)
Protein Eng. Des. Sel.
, vol.19
, pp. 497-502
-
-
Barkhordarian, H.1
Emadi, S.2
Schulz, P.3
Sierks, M.R.4
-
56
-
-
34147130637
-
Isolation of a human single chain antibody fragment against oligomeric alpha-synuclein that inhibits aggregation and prevents alpha-synuclein-induced toxicity
-
Emadi S., Barkhordarian H., Wang M.S., Schulz P., and Sierks M.R. Isolation of a human single chain antibody fragment against oligomeric alpha-synuclein that inhibits aggregation and prevents alpha-synuclein-induced toxicity. J. Mol. Biol. 368 (2007) 1132-1144
-
(2007)
J. Mol. Biol.
, vol.368
, pp. 1132-1144
-
-
Emadi, S.1
Barkhordarian, H.2
Wang, M.S.3
Schulz, P.4
Sierks, M.R.5
-
57
-
-
33748796622
-
Identification of human alpha-synuclein specific single chain antibodies
-
Maguire-Zeiss K.A., Wang C.I., Yehling E., Sullivan M.A., Short D.W., Su X., Gouzer G., Henricksen L.A., Wuertzer C.A., and Federoff H.J. Identification of human alpha-synuclein specific single chain antibodies. Biochem. Biophys. Res. Commun. 349 (2006) 1198-1205
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.349
, pp. 1198-1205
-
-
Maguire-Zeiss, K.A.1
Wang, C.I.2
Yehling, E.3
Sullivan, M.A.4
Short, D.W.5
Su, X.6
Gouzer, G.7
Henricksen, L.A.8
Wuertzer, C.A.9
Federoff, H.J.10
-
58
-
-
0035951869
-
A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly
-
Giasson B.I., Murray I.V., Trojanowski J.Q., and Lee V.M. A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly. J. Biol. Chem. 276 (2001) 2380-2386
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2380-2386
-
-
Giasson, B.I.1
Murray, I.V.2
Trojanowski, J.Q.3
Lee, V.M.4
-
59
-
-
0034922671
-
Identification of the region of non-Abeta component (NAC) of Alzheimer's disease amyloid responsible for its aggregation and toxicity
-
Bodles A.M., Guthrie D.J., Greer B., and Irvine G.B. Identification of the region of non-Abeta component (NAC) of Alzheimer's disease amyloid responsible for its aggregation and toxicity. J. Neurochem. 78 (2001) 384-395
-
(2001)
J. Neurochem.
, vol.78
, pp. 384-395
-
-
Bodles, A.M.1
Guthrie, D.J.2
Greer, B.3
Irvine, G.B.4
-
60
-
-
0032540327
-
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
-
Davidson W.S., Jonas A., Clayton D.F., and George J.M. Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes. J. Biol. Chem. 273 (1998) 9443-9449
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9443-9449
-
-
Davidson, W.S.1
Jonas, A.2
Clayton, D.F.3
George, J.M.4
-
61
-
-
0037137224
-
Structural and functional implications of C-terminal regions of alpha-synuclein
-
Kim T.D., Paik S.R., and Yang C.H. Structural and functional implications of C-terminal regions of alpha-synuclein. Biochemistry 41 (2002) 13782-13790
-
(2002)
Biochemistry
, vol.41
, pp. 13782-13790
-
-
Kim, T.D.1
Paik, S.R.2
Yang, C.H.3
-
62
-
-
0029019742
-
Protein motion and lock and key complementarity in antigen-antibody reactions
-
Braden B.C., Dall'Acqua W., Eisenstein E., Fields B.A., Goldbaum F.A., Malchiodi E.L., Mariuzza R.A., Schwarz F.P., Ysern X., and Poljak R.J. Protein motion and lock and key complementarity in antigen-antibody reactions. Pharm. Acta Helv. 69 (1995) 225-230
-
(1995)
Pharm. Acta Helv.
, vol.69
, pp. 225-230
-
-
Braden, B.C.1
Dall'Acqua, W.2
Eisenstein, E.3
Fields, B.A.4
Goldbaum, F.A.5
Malchiodi, E.L.6
Mariuzza, R.A.7
Schwarz, F.P.8
Ysern, X.9
Poljak, R.J.10
-
63
-
-
0345189364
-
Yeast cells provide insight into alpha-synuclein biology and pathobiology
-
Outeiro T.F., and Lindquist S. Yeast cells provide insight into alpha-synuclein biology and pathobiology. Science 302 (2003) 1772-1775
-
(2003)
Science
, vol.302
, pp. 1772-1775
-
-
Outeiro, T.F.1
Lindquist, S.2
-
64
-
-
0035870881
-
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
-
Tanaka Y., Engelender S., Igarashi S., Rao R.K., Wanner T., Tanzi R.E., Sawa A., Dawson L., Dawson T.M., and Ross C.A. Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Hum. Mol. Genet. 10 (2001) 919-926
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 919-926
-
-
Tanaka, Y.1
Engelender, S.2
Igarashi, S.3
Rao, R.K.4
Wanner, T.5
Tanzi, R.E.6
Sawa, A.7
Dawson, L.8
Dawson, T.M.9
Ross, C.A.10
-
65
-
-
0034595728
-
Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells
-
Zhou W., Hurlbert M.S., Schaack J., Prasad K.N., and Freed C.R. Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells. Brain Res. 866 (2000) 33-43
-
(2000)
Brain Res.
, vol.866
, pp. 33-43
-
-
Zhou, W.1
Hurlbert, M.S.2
Schaack, J.3
Prasad, K.N.4
Freed, C.R.5
-
66
-
-
0037118259
-
Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein
-
Giasson B., Duda J.E., Quinn S.M., Zhang B., Trojanowski J.Q., and Lee V.M. Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron 34 (2002) 521-533
-
(2002)
Neuron
, vol.34
, pp. 521-533
-
-
Giasson, B.1
Duda, J.E.2
Quinn, S.M.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.6
-
67
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany M.B., and Bender W.W. A Drosophila model of Parkinson's disease. Nature 404 (2000) 394-398
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
68
-
-
0037971209
-
Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein
-
Lakso M., Vartiainen S., Moilanen A.M., Sirvio J., Thomas J.H., Nass R., Blakely R.D., and Wong G. Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein. J. Neurochem. 86 (2003) 165-172
-
(2003)
J. Neurochem.
, vol.86
, pp. 165-172
-
-
Lakso, M.1
Vartiainen, S.2
Moilanen, A.M.3
Sirvio, J.4
Thomas, J.H.5
Nass, R.6
Blakely, R.D.7
Wong, G.8
-
69
-
-
33644943789
-
Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein
-
Pavoni E., Flego M., Dupuis M.L., Barca S., Petronzelli F., Anastasi A.M., D'Alessio V., Pelliccia A., Vaccaro P., Monteriu G., Ascione A., De Santis R., Felici F., Cianfriglia M., and Minenkova O., Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein. BMC Cancer 6 (2006) 41
-
(2006)
BMC Cancer
, vol.6
, pp. 41
-
-
Pavoni, E.1
Flego, M.2
Dupuis, M.L.3
Barca, S.4
Petronzelli, F.5
Anastasi, A.M.6
D'Alessio, V.7
Pelliccia, A.8
Vaccaro, P.9
Monteriu, G.10
Ascione, A.11
De Santis, R.12
Felici, F.13
Cianfriglia, M.14
Minenkova, O.15
-
70
-
-
27544483522
-
Directed evolution for the development of conformation-specific affinity reagents using yeast display
-
Weaver-Feldhaus J.M., Miller K.D., Feldhaus M.J., and Siegel R.W. Directed evolution for the development of conformation-specific affinity reagents using yeast display. Protein Eng. Des. Sel. 18 (2005) 527-536
-
(2005)
Protein Eng. Des. Sel.
, vol.18
, pp. 527-536
-
-
Weaver-Feldhaus, J.M.1
Miller, K.D.2
Feldhaus, M.J.3
Siegel, R.W.4
-
71
-
-
28044460070
-
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
-
West A.B., Moore D.J., Biskup S., Bugayenko A., Smith W.W., Ross C.A., Dawson V.L., and Dawson T.M. Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 16842-16847
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 16842-16847
-
-
West, A.B.1
Moore, D.J.2
Biskup, S.3
Bugayenko, A.4
Smith, W.W.5
Ross, C.A.6
Dawson, V.L.7
Dawson, T.M.8
-
72
-
-
33748993710
-
Kinase activity of mutant LRRK2 mediates neuronal toxicity
-
Smith W.W., Pei Z., Jiang H., Dawson V.L., Dawson T.M., and Ross C.A. Kinase activity of mutant LRRK2 mediates neuronal toxicity. Nat. Neurosci. 9 (2006) 1231-1233
-
(2006)
Nat. Neurosci.
, vol.9
, pp. 1231-1233
-
-
Smith, W.W.1
Pei, Z.2
Jiang, H.3
Dawson, V.L.4
Dawson, T.M.5
Ross, C.A.6
-
73
-
-
33846562487
-
Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity
-
West A.B., Moore D.J., Choi C., Andrabi S.A., Li X., Dikeman D., Biskup S., Zhang Z., Lim K.L., Dawson V.L., and Dawson T.M. Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity. Hum. Mol. Genet. 16 (2007) 223-232
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 223-232
-
-
West, A.B.1
Moore, D.J.2
Choi, C.3
Andrabi, S.A.4
Li, X.5
Dikeman, D.6
Biskup, S.7
Zhang, Z.8
Lim, K.L.9
Dawson, V.L.10
Dawson, T.M.11
-
74
-
-
33746267531
-
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
-
Greggio E., Jain S., Kingsbury A., Bandopadhyay R., Lewis P., Kaganovich A., van der Brug M.P., Beilina A., Blackinton J., Thomas K.J., Ahmad R., Miller D.W., Kesavapany S., Singleton A., Lees A., Harvey R.J., Harvey K., and Cookson M.R. Kinase activity is required for the toxic effects of mutant LRRK2/dardarin. Neurobiol. Dis. 23 (2006) 329-341
-
(2006)
Neurobiol. Dis.
, vol.23
, pp. 329-341
-
-
Greggio, E.1
Jain, S.2
Kingsbury, A.3
Bandopadhyay, R.4
Lewis, P.5
Kaganovich, A.6
van der Brug, M.P.7
Beilina, A.8
Blackinton, J.9
Thomas, K.J.10
Ahmad, R.11
Miller, D.W.12
Kesavapany, S.13
Singleton, A.14
Lees, A.15
Harvey, R.J.16
Harvey, K.17
Cookson, M.R.18
-
75
-
-
47749114984
-
The Parkinson Disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation
-
Greggio E., Zambrano I., Kaganovich A., Beilina A., Taymans J.M., Daniels V., Lewis P., Jain S., Ding J., Syed A., Thomas K.J., Baekelandt V., and Cookson M.R. The Parkinson Disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation. J. Biol. Chem. 283 (2008) 16906-16914
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 16906-16914
-
-
Greggio, E.1
Zambrano, I.2
Kaganovich, A.3
Beilina, A.4
Taymans, J.M.5
Daniels, V.6
Lewis, P.7
Jain, S.8
Ding, J.9
Syed, A.10
Thomas, K.J.11
Baekelandt, V.12
Cookson, M.R.13
-
76
-
-
29444437871
-
Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration
-
Smith W.W., Pei Z., Jiang H., Moore D.J., Liang Y., West A.B., Dawson V.L., Dawson T.M., and Ross C.A. Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration. Proc. Natl Acad. Sci. U. S. A 102 (2005) 18676-18681
-
(2005)
Proc. Natl Acad. Sci. U. S. A
, vol.102
, pp. 18676-18681
-
-
Smith, W.W.1
Pei, Z.2
Jiang, H.3
Moore, D.J.4
Liang, Y.5
West, A.B.6
Dawson, V.L.7
Dawson, T.M.8
Ross, C.A.9
-
77
-
-
33751256567
-
The familial Parkinsonism gene LRRK2 regulates neurite process morphology
-
MacLeod D., Dowman J., Hammond R., Leete T., Inoue K., and Abeliovich A. The familial Parkinsonism gene LRRK2 regulates neurite process morphology. Neuron 52 (2006) 587-593
-
(2006)
Neuron
, vol.52
, pp. 587-593
-
-
MacLeod, D.1
Dowman, J.2
Hammond, R.3
Leete, T.4
Inoue, K.5
Abeliovich, A.6
-
78
-
-
46549089664
-
LRRK2 regulates synaptic vesicle endocytosis
-
Shin N., Jeong H., Kwon J., Heo H.Y., Kwon J.J., Yun H.J., Kim C.H., Han B.S., Tong Y., Shen J., Hatano T., Hattori N., Kim K.S., Chang S., and Seol W. LRRK2 regulates synaptic vesicle endocytosis. Exp. Cell Res. 314 (2008) 2055-2065
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 2055-2065
-
-
Shin, N.1
Jeong, H.2
Kwon, J.3
Heo, H.Y.4
Kwon, J.J.5
Yun, H.J.6
Kim, C.H.7
Han, B.S.8
Tong, Y.9
Shen, J.10
Hatano, T.11
Hattori, N.12
Kim, K.S.13
Chang, S.14
Seol, W.15
-
79
-
-
33845298032
-
Localization of LRRK2 to membranous and vesicular structures in mammalian brain
-
Biskup S., Moore D.J., Celsi F., Higashi S., West A.B., Andrabi S.A., Kurkinen K., Yu S.W., Savitt J.M., Waldvogel H.J., Faull R.L., Emson P.C., Torp R., Ottersen O.P., Dawson T.M., and Dawson V.L. Localization of LRRK2 to membranous and vesicular structures in mammalian brain. Ann. Neurol. 60 (2006) 557-569
-
(2006)
Ann. Neurol.
, vol.60
, pp. 557-569
-
-
Biskup, S.1
Moore, D.J.2
Celsi, F.3
Higashi, S.4
West, A.B.5
Andrabi, S.A.6
Kurkinen, K.7
Yu, S.W.8
Savitt, J.M.9
Waldvogel, H.J.10
Faull, R.L.11
Emson, P.C.12
Torp, R.13
Ottersen, O.P.14
Dawson, T.M.15
Dawson, V.L.16
-
80
-
-
34247098407
-
Leucine-rich repeat kinase 2 associates with lipid rafts
-
Hatano T., Kubo S., Imai S., Maeda M., Ishikawa K., Mizuno Y., and Hattori N. Leucine-rich repeat kinase 2 associates with lipid rafts. Hum. Mol. Genet. 16 (2007) 678-690
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 678-690
-
-
Hatano, T.1
Kubo, S.2
Imai, S.3
Maeda, M.4
Ishikawa, K.5
Mizuno, Y.6
Hattori, N.7
-
81
-
-
45549085874
-
The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules
-
Gandhi P.N., Wang X., Zhu X., Chen S.G., and Wilson-Delfosse A.L. The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules. J. Neurosci. Res. 86 (2008) 1711-1720
-
(2008)
J. Neurosci. Res.
, vol.86
, pp. 1711-1720
-
-
Gandhi, P.N.1
Wang, X.2
Zhu, X.3
Chen, S.G.4
Wilson-Delfosse, A.L.5
-
82
-
-
50149121528
-
The kinase domain of mitochondrial PINK1 faces the cytoplasm
-
Zhou C., Huang Y., Shao Y., May J., Prou D., Perier C., Dauer W., Schon E.A., and Przedborski S. The kinase domain of mitochondrial PINK1 faces the cytoplasm. Proc. Natl. Acad. Sci. U. S. A 105 (2008) 12022-12027
-
(2008)
Proc. Natl. Acad. Sci. U. S. A
, vol.105
, pp. 12022-12027
-
-
Zhou, C.1
Huang, Y.2
Shao, Y.3
May, J.4
Prou, D.5
Perier, C.6
Dauer, W.7
Schon, E.A.8
Przedborski, S.9
|