Gentamicin-induced preconditioning of proximal tubular LLC-PK1 cells stimulates nitric oxide production but not the synthesis of heat shock protein

Brazilian Journal of Medical and Biological Research

Volumn 42, Issue 7, 2009, Pages 614-620

  Pessoa, E A ^a   Convento, M B ^a   Silva, R G ^a   Oliveira, A S ^a   Borges, F T ^a   Schor, Nestor ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Acute kidney injury; Apoptosis; Gentamicin; LLC PK1 cells; Nitric oxide; Pre conditioning

Indexed keywords

ENDOTHELIN 1; GENTAMICIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL PROTECTION; CELL STIMULATION; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; KIDNEY PROXIMAL TUBULAR CELL PRECONDITIONING; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; NONHUMAN; PROCEDURES CONCERNING CELLS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; WESTERN BLOTTING;

EID: 68649101475     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2009005000005     Document Type: Article

References (38)

1. Plesset J, Palm C, McLaughlin CS. Induction of heat shock proteins and thermotolerance by ethanol in Saccharomyces cerevisiae. Biochem Biophys Res Commun 1982; 108: 1340-1345.
2. Yellon DM, Latchman DS. Stress proteins and myocardial protection. J Mol Cell Cardiol 1992; 24: 113-124.
3. Perez-Pinzon MA, Xu GP, Dietrich WD, Rosenthal M, Sick TJ. Rapid preconditioning protects rats against ischemic neuronal damage after 3 but not 7 days of reperfusion following global cerebral ischemia. J Cereb Blood Flow Metab 1997; 17: 175-182.
4. Lee HT, Lineaweaver WC. Protection against ischemic-reperfusion injury of skeletal muscle: role of ischemic preconditioning and adenosine pretreatment. J Reconstr Microsurg 1996; 12: 383-388.
5. Lloris-Carsi JM, Cejalvo D, Toledo-Pereyra LH, Calvo MA, Suzuki S. Preconditioning: effect upon lesion modulation in warm liver ischemia. Transplant Proc 1993; 25: 3303-3304.
6. Hotter G, Closa D, Prados M, Fernandez-Cruz L, Prats N, Gelpi E, et al. Intestinal preconditioning is mediated by a transient increase in nitric oxide. Biochem Biophys Res Commun 1996; 222: 27-32.
7. Neely CF, Keith IM. A1 adenosine receptor antagonists block ischemia-reperfusion injury of the lung. Am J Physiol 1995; 268: L1036-L1046.
8. Cochrane J, Williams BT, Banerjee A, Harken AH, Burke TJ, Cairns CB, et al. Ischemic preconditioning attenuates functional, metabolic, and morphologic injury from ischemic acute renal failure in the rat. Ren Fail 1999; 21: 135-145.
9. Rordorf G, Koroshetz WJ, Bonventre JV. Heat shock protects cultured neurons from glutamate toxicity. Neuron 1991; 7: 1043-1051.
10. Kim YO, Li C, Sun BK, Kim JS, Lim SW, Choi BS, et al. Preconditioning with 1,25-dihydroxyvitamin D3 protects against subsequent ischemia-reperfusion injury in the rat kidney. Nephron Exp Nephrol 2005; 100: e85-e94.
11. Mahfoudh-Boussaid A, Badet L, Zaouali A, Saidane-Mosbahi D, Miled A, Ben AH. [Effect of ischaemic preconditioning and vitamin C on functional recovery of ischaemic kidneys]. Prog Urol 2007; 17: 836-840.
12. Lowenstein DH, Chan PH, Miles MF. The stress protein response in cultured neurons: characterization and evidence for a protective role in excitotoxicity. Neuron 1991; 7: 1053-1060.
13. Sugino H, Shimada H, Tsuchimoto K. Role of adenosine in renal protection induced by a brief episode of ischemic preconditioning in rats. Jpn J Pharmacol 2001; 87: 134-142.
14. Shinmura K, Nagai M, Tamaki K, Tani M, Bolli R. COX-2-derived prostacyclin mediates opioid-induced late phase of preconditioning in isolated rat hearts. Am J Physiol Heart Circ Physiol 2002; 283: H2534-H2543.
15. Kositprapa C, Ockaili RA, Kukreja RC. Bradykinin B2 receptor is involved in the late phase of preconditioning in rabbit heart. J Mol Cell Cardiol 2001; 33: 1355-1362.
16. +-ATPase modulates ischemic preconditioning. Circulation 1998; 98: 2905-2910.
17. Saito T, Fushimi E, Tamura T, Fujiwara Y, Miura H, Watanabe H, et al. L-nitro-arginine inhibits increase in endothelin binding sites induced by ischemia and reperfusion. J Mol Cell Cardiol 2002; 34: 1041-1047.
18. Heads RJ, Latchman DS, Yellon DM. Stable high level expression of a transfected human HSP70 gene protects a heart-derived muscle cell line against thermal stress. J Mol Cell Cardiol 1994; 26: 695-699.
19. Lindquist S. Translational efficiency of heat-induced messages in Drosophila melanogaster cells. J Mol Biol 1980; 137: 151-158.
20. Lindquist S, Craig EA. The heat-shock proteins. Annu Rev Genet 1988; 22: 631-677.
21. Chander V, Chopra K. Role of nitric oxide in resveratrol-induced renal protective effects of ischemic preconditioning. J Vasc Surg 2005; 42: 1198-1205.
22. Ali BH. Gentamicin nephrotoxicity in humans and animals: some recent research. Gen Pharmacol 1995; 26: 1477-1487.
23. Bennett WM. Comparison of cyclosporine nephrotoxicity with aminoglycoside nephrotoxicity. Clin Nephrol 1986; 25 (Suppl 1): S126-S129.
24. Cuzzocrea S, Mazzon E, Dugo L, Serraino I, Di Paola R, Britti D, et al. A role for superoxide in gentamicin-mediated nephropathy in rats. Eur J Pharmacol 2002; 450: 67-76.
25. Schor N, Ichikawa I, Rennke HG, Troy JL, Brenner BM. Pathophysiology of altered glomerular function in aminoglycoside-treated rats. Kidney Int 1981; 19: 288-296.
26. Levin A, Pate GE, Shalansky S, Al-Shamari A, Webb JG, Buller CE, et al. N-acetylcysteine reduces urinary albumin excretion following contrast administration: evidence of biological effect. Nephrol Dial Transplant 2007; 22: 2520-2524.
27. Coico R. In vitro assays for mouse B and T cell function. Related isolation procedures and functional assays. In: Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W (Editors), Current protocols in immunology. Vol. 3.17. New York: John Wiley & Sons, Inc.; 1995. p 1-33.
28. Filatov MV, Varfolomeeva EY. Active dissociation of Hoechst 33342 from DNA in living mammalian cells. Mutat Res 1995; 327: 209-215.
29. Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal Biochem 1982; 126: 131-138.
30. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193: 265-275.
31. Kacew S, Bergeron MG. Pathogenic factors in aminoglycoside-induced nephrotoxicity. Toxicol Lett 1990; 51: 241-259.
32. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 1986; 74: 1124-1136.
33. Rivas-Cabanero L, Montero A, Lopez-Novoa JM. Increased glomerular nitric oxide synthesis in gentamicin-induced renal failure. Eur J Pharmacol 1994; 270: 119-121.
34. Sasser JM, Sullivan JC, Hobbs JL, Yamamoto T, Pollock DM, Carmines PK, et al. Endothelin A receptor blockade reduces diabetic renal injury via an anti-inflammatory mechanism. J Am Soc Nephrol 2007; 18: 143-154.
35. Yamashita J, Ogata M, Itoh M, Yamasowa H, Shimeda Y, Takaoka M, et al. Role of nitric oxide in the renal protective effects of ischemic preconditioning. J Cardiovasc Pharmacol 2003; 42: 419-427.
36. Liu X, Chen H, Zhan B, Xing B, Zhou J, Zhu H, et al. Attenuation of reperfusion injury by renal ischemic post-conditioning: the role of NO. Biochem Biophys Res Commun 2007; 359: 628-634.
37. Amin V, Cumming DV, Coffin RS, Latchman DS. The degree of protection provided to neuronal cells by a preconditioning stress correlates with the amount of heat shock protein 70 it induces and not with the similarity of the subsequent stress. Neurosci Lett 1995; 200: 85-88.
38. Turman MA, Rosenfeld SL. Heat shock protein 70 over-expression protects LLC-PK1 tubular cells from heat shock but not hypoxia. Kidney Int 1999; 55: 189-197.