Potential neoplastic effects of parathion-methyl on rat liver

Journal of Environmental Sciences

Volumn 21, Issue 5, 2009, Pages 696-699

  Coral, M Nisa Unaldi ^a   Ucman, Sonay ^b   Hasan, Yildiz ^b   Haydar, Oztas ^c   Semih, Dalkilic ^d  

^a MERSIN UNIVERSITY   (Turkey)

^b MUSTAFA KEMAL UNIVERSITY   (Turkey)

^c SELCUK UNIVERSITY   (Turkey)

^d ANKARA UNIVERSITY   (Turkey)

Author keywords

Ames test; atypical acinar cell focuses; carcinogenesis; parathion methyl

Indexed keywords

ACINAR CELLS; AMES TEST; ATYPICAL ACINAR CELL FOCUSES; BACTERIAL CELLS; CARCINOGENESIS; CARCINOGENIC EFFECTS; HEPATOCYTES; LONG-TERM EXPERIMENTS; METABOLIC ACTIVATION; MUTAGENIC EFFECT; NEOPLASTIC EFFECTS; PARATHION-METHYL; PATHOLOGICAL CHANGES; RAT LIVERS; REVERSE MUTATION; SALMONELLA TYPHIMURIUM; WISTAR RAT;

BACTERIOLOGY; CELL MEMBRANES; DRUG PRODUCTS; EXPERIMENTS; LIVER; PATHOLOGY; RATS;

BIOINFORMATICS;

CARCINOGEN; INSECTICIDE; PARATHION METHYL;

CARCINOGEN; EXPERIMENTAL STUDY; MUTAGENICITY; ORGANOPHOSPHATE; PATHOLOGY; RODENT;

ANIMAL; ARTICLE; BIOTRANSFORMATION; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; GENETICS; LIVER; LIVER TUMOR; MALE; PATHOLOGY; RAT; SALMONELLA TYPHIMURIUM; WISTAR RAT;

ANIMALS; BIOTRANSFORMATION; CARCINOGENS; INSECTICIDES; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; METHYL PARATHION; RATS; RATS, WISTAR; SALMONELLA TYPHIMURIUM;

BACTERIA (MICROORGANISMS); RATTUS; RATTUS NORVEGICUS; SALMONELLA TYPHIMURIUM;

EID: 68649095914     PISSN: 10010742     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1001-0742(08)62326-8     Document Type: Article

References (25)

1. Adgate J., Barr D.B., Clayton C.A., Eberly L.E., Freeman N.C.G., Lioy P.J., et al. Measurement of children's exposure to pesticides: analysis of urinary metabolite levels in a probability - based sample. Environmental Health Perspectives 109 (2001) 583-590
2. Alavanja M.C.R., Akland G., and Baird D. Cancer and noncancer risk to women in agriculture and pest control: the agricultural health study. Journal of Occupational and Environmental Medicine 36 11 (1994) 1247-1250
3. Ames B.N., Mccann J., and Yamasaki E. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian microsome mutagenity test. Mutation Research 31 (1975) 347-364
4. Bannash P., Benner U., Enzmann H., and Hacker H.J. Tigroid cell foci and neoplastic nodules in the liver of rats treated with a single dose of aflatoxin B1. Carcinogenesis 6 (1985) 1641-1648
5. Coats J.R. Mechanisms of toxic action and structure-activity relationships for organochlorine and synthetic pyrethroid insecticides. Environmental Health Perspectives 87 (1990) 255-262
6. Delen N, Durmuşoǧlu E, Güncan A, Güngör N, Turgut C, Burçak A, 2005. Pesticides usage in Turkey, problems of residue and reduction of organisms' sensitivity. Türkiye Ziraat Mühendisligi, 6. Teknik Kongre. 21.
7. Devlet Statistik Enstitüsü D E, 1993. Annual Statistics of Turkey. Ankara, Turkey.
8. Dich J., Zahm S.H., Hanberg A., and Adami H.O. Pesticides and cancer. Cancer Causes Control 8 (1997) 420
9. Dinham B, 1993. The Pesticides Hazard, The Pesticides Trust (now PAN UK), 105.
10. Gallo M.A., and Lawryk N.J. Organic phosphorus pesticides. In: Hayes Jr. W.J., and Laws Jr. E.R. (Eds). Handbook of Pesticide Toxicology (1991), Academic Press, New York
11. Hallenbeck W.H., and Cunningham-Burns K.M. Pesticides and Human Health (1985), Springer-Verlag, New York
12. Herrera A., Barrueco C., Caballo C., and de la Pena E. Effect of permethrin on the induction of sister chromatid exchanges and micronuclei in cultured human lymphocytes. Environmental Molecular Mutagenesis 20 (1992) 218-222
13. Kumuk T., and Akgüngör S. The role of public extension in introducing environment-friendly farming methods in Turkey. Journal of Agriculturel Education and Extension 1 4 (1995) 65-74
14. Kutz F.W., Cook B.T., Carter-Pokras O.D., Brody D., and Murphy R.S. Selected pesticide residues and metabolites in urine from a survey of the U.S. general population. Journal of Toxicology and Environmental Health 37 (1992) 277-291
15. Maron D.M., and Ames B.N. Revised methods for the Salmonella mutagenecity test. Mutation Research 113 (1983) 173-215
16. Mathew G., Rahiman M.A., and Vijayalaxmi K. In vivo geno-toxic effects in mice of Metacid 50, an organophosphorus insecticide. Mutagenesis 5 2 (1990) 147-150
17. Meyer S.A., Moser G.J., Monteiro-Riviere N.A., and Smart R.C. Minimal role of enhanced cell proliferation in skin tumor promotion by mirex: a nonphorbol ester-type promoter. Environmental Health Perspectives 101 5 (1993) 265-269
18. Moser G.J., and Smart R.C. Hepatic tumor-promoting chlorinated hydrocarbons stimulate protein kinase C activity. Carcinogenesis 10 5 (1989) 851-856
19. Roebuck B.D., Baumgartner K.J., and Thron C.D. Characterization of two populations of pancreatic atypical cell foci induced by azaserine in the rat. Laboratory Investigation 50 2 (1984) 141-146
20. Tomlin C. The Pesticide Manual. 10th ed. (1994), British Crop Protection Council, United Kingdom
21. Wagner E.D., Marengo M.S., and Plewa M.J. Modulation of the mutagenicity of heterocyclic amines by organophosphate insecticides and their metabolites. Mutation Research 536 (2003) 103-115
22. WHO (World Health Organization), 1996. The WHO Recommended Classification of Pesticides by Hazard, International Programme on Chemical Safety, Geneva.
23. Williams G.M. Epigenetic effects of liver tumor promoters and implications for health effects. Environmental Health Perspectives 50 (1983) 177-183
24. Woodruff R.C., Phillips J.P., and Lrwin D. Pesticide-induced complete and partial chromosome loss in screens with repair-defective females of Drosophila melanogaster. Environmental Mutagenesis 5 (1983) 835-846
25. World Sources. The United Nations Environment Programme, the United Nations Development Programme and the World Bank. A Joint Publication by the World Resources Institute (1999), Oxford University Press, Oxford 41