Shear and AC field enhanced carbon nanotube impedance assay for rapid, sensitive, and mismatch-discriminating DNA hybridization

ACS Nano

Volumn 3, Issue 7, 2009, Pages 1823-1830

  Basuray, Sagnik ^a   Senapati, Satyajyoti ^a   Aijian, Andrew ^a   Mahon, Andrew R ^b   Chang, Hsueh Chia ^a  

^a University of Notre Dame   (United States)

^b Center for Aquatic Conservation   (United States)

Author keywords

Bioassay; Carbon nanotube; DNA hybridization; Impedance; Open flow

Indexed keywords

AC ELECTRIC FIELD; AC FIELD; AC-IMPEDANCE; CHARGE-TRANSFER; CHARGE-TRANSFER RATE; DNA CONCENTRATION; DNA HYBRIDIZATION; DOUBLE LAYERS; FLOW IMPEDANCES; HIGH FREQUENCY HF; IMPEDANCE; ION TRANSPORTS; LABEL FREE; MICROFLUIDIC DETECTION; OPEN FLOW; SENSING PLATFORMS; SENSITIVE DETECTION; SENSOR LOCATION; TARGET MOLECULE;

BIOASSAY; DNA; ELECTRIC FIELDS; GENES; LABELS; NUCLEIC ACIDS; SIGNAL DETECTION;

CARBON NANOTUBES;

EID: 68649092365     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn9004632     Document Type: Article

References (35)

1. Hutvagner, G.; Mclachlan, J.; Pasquinelli, A. E.; Balint, E.; Tuschl, T.; Zamore, P. D. A Cellular Function for the RNAInterference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA. Science 2001, 293, 834-838.
2. Palecek, E. Surface-Attached Molecular Beacons Light the Way for DNA Sequencing. Trends Biotechnol. 2004, 22, 55-58.
3. Tu, I.-P.; Schaner, M.; Diehn, M.; Sikic, B. I.; Brown, P. O.; Botstein, D.; Fero, M. J. A Method for Detecting and Correcting Feature Misidentification on Expression Microarrays. BMC Genomics 2004, 5, 64.
4. Tüdos, A. J.; Besselink, G. A. J.; Schasfoort, R. B. M. Trends in Miniaturized Total Analysis Systems for Point-Of-Care Testing in Clinical Chemistry. Lab Chip 2001, 1, 83-95.
5. Kian-Kok Ng, J.; Feng, H.; Liu, W. T. Rapid Discrimination of Single-Nucleotide Mismatches Using a Microfluidic Device with Monolayered Beads. Anal. Chim. Acta 2007, 582, 295-303.
6. Chang, H.-C. Nanobead Electrokinetics: The Enabling Microfluidic Platform for Rapid Multi-Target Pathogen Detection. AIChE J. 2007, 53, 2486-2492.
7. Sengupta, S.; Battigelli, D. A.; Chang, H.-C. A Micro-Scale Multi-Frequency Reactance Measurement Technique to Detect Bacterial Growth at Low Bio-Particle Concentrations. Lap Chip 2006, 6, 682-692.
8. Balassubramanian, K.; Burghard, M. Biosensors Based on Carbon Nanotubes. Anal. Bioanal. Chem. 2006, 385, 452-568.
9. Kelley, S. O.; Holmlin, R. E.; Stemp, E. D. A.; Barton, J. K. Photoinduced Electron Transfer in Ethidium-Modified DNA Duplexes: Dependence on Distance and Base Stacking. J. Am. Chem. Soc. 1997, 119, 9861-9870.
10. Guo, X.; Gorodetsky, A. A.; Hone, J.; Barton, J. K.; Nuckolls, C. Conductivity of a Single DNA Duplex Bridging a Carbon Nanotube Gap. Nat. Nanotechnol. 2008, 3, 163-167.
11. Degefa, T. H.; Kwak, J. Electrochemical Impedance Sensing of DNA at PNA Self Assembled Monolayer. J. Electroanal. Chem. 2008, 612, 37-41.
12. Kuhr, W. G. Electrochemical DNA Analysis Comes of Age. Nat. Biotechnol. 2000, 18, 1042-1043.
13. Sosnowski, R. G.; Tu, E.; Butler, W. F.; O'Connell, J. P.; Heller, M. J. Rapid Determination of Single Base Mismatch Mutations in DNA Hybrids by Direct Electric Field Control. Proc. Natl. Acad. Sci. U.S.A. 1997, 94, 1119-1123.
14. Zhou, R.; Wang, P.; Chang, H.-C. Bacteria Capture, Concentration and Detection by Alternating Current Dielectrophoresis and Self-Assembly of Dispersed Single- Wall Carbon Nanotubes. Electrophoresis 2006, 27, 1376-1385.
15. Li, J.; Hou, T. N.; Cassell, A.; Fan, W.; Chen, H.; Ye, Q.; Koehne, J.; Han, J.; Meyyappan, M. Carbon Nanotube Nanoelectrode Array for Ultrasensitive DNA Detection. Nano Lett. 2003, 3, 597-602.
16. Maehashi, K.; Matsumoto, K.; Kerman, K.; Takamura, Y.; Tamiya, E. Ultrasensitive Detection of DNA Hybridization Using Carbon Nanotube Field-Effect Transistors. Jpn. J. Appl. Phys. 2004, 43, L1558-L1560.
17. Xu, Y.; Ye, X.; Yang, L.; He, P.; Fang, Y. Impedance DNA Biosensor Using Electropolymerized Polypyrrole/Multiwalled Carbon Nanotubes Modified Electrode. Electroanalysis 2006, 18, 1471-1478.
18. Dawson, J. L.; John, D. G. Diffusion ImpedanceOAn Extended General Analysis. J. Electroanal. Chem. 1980, 10, 37-47.
19. Sambrook, J.; Fritsch, E. F.; Maniatis, T. Molecule Cloning: A Laboratory Manual; 2nd ed.; Cold Spring Harbor: New York, 1989.
20. Varma, R.; Selman, J. R. Techniques for Characterization of Electrodes and Electrochemical Processes; Wiley: New York, 1991.
21. Bard, A. J.; Faulkne, L. R. Electrochemical Methods: Fundamentals and Applications; Wiley: New York, 1980.
22. Mauracher, P.; Karden, E. Dynamic Modelling of Lead/Acid Batteries Using Impedance Spectroscopy for Parameter Identification. J. Power Sources 1997, 67, 69-84.
23. Taylor, S. R.; Gileadi, E. Physical Interpretation of the Warburg Impedance. Corrosion 1995, 51, 664-671.
24. Muralidharan, V. S. Warburg Impedance-Basics Revisited. Anti-Corros. Methods Mater. 1997, 44, 26-29.
25. Cai, H.; Cao, X.; Jiang, Y.; He, P.; Fang, Y. Carbon Nanotube- Enhanced Electrochemical DNA Biosensor for DNA Hybridization Detection. Anal. Bioanal. Chem. 2003, 375, 287-293. (Pubitemid 41201307)
26. Bardea, A.; Katz, E.; Willner, I. Probing Antigen-Antibody Interactions on Electrode Supports by the Biocatalyzed Precipitation of an Insoluble Product. Electroanalysis 2000, 12, 1097-1106.
27. Xu, Y.; Jiang, Y.; Cai, H.; He, P.-G.; Fang, Y.-Z. Electrochemical Impedance Detection of DNA Hybridization Based on the Formation of M-DNA on Polypyrrole/Carbon Nanotube Modified Electrode. Anal. Chim. Acta 2004, 516, 19-27.
28. Mahon, A. R. Unpublished data.
29. Senapati, S.; Mahon, A. R.; Gordon, J.; Nowak, C.; Sengupta, S.; Powell, T. H. W.; Feder, J.; Lodge, D. M.; Chang, H.-C. Rapid On-Chip Genetic Detection Microfluidic Platform for Real World Applications. Biomicrofluidics 2009, 3, 022407-7.
30. Kim, D. R.; Zheng, X. Numerical Characterization and Optimization of the Microfluidics for Nanowire Biosensors. Nano Lett. 2008, 8, 3233-3237.
31. Asbury, C. L.; Engh, G. V. D. Trapping of DNA in Nonuniform Oscillating Electric Fields. Biophys. J. 1998, 74, 1024-1030.
32. Asbury, C. L.; Diercks, A. H.; Engh, G. V. D. Trapping of DNA by Dielectrophoresis. Electrophoresis 2002, 23, 2658-2666.
33. Gagnon, Z.; Senapati, S.; Gordon, J.; Chang, H.-C. Dielectrophoretic Detection and Quantification of Hybridized DNA Molecules on Nano-Genetic Particles. Electrophoresis 2008, 29, 4808-4812.
34. Rouzina, I.; Bloomfield, V. A. DNA Bending by Small, Mobile Multivalent Cations. Biophys. J. 1998, 74, 3152-3164.
35. Marquette, C. A.; Blum, L. J. Beads Arraying and Beads Used in DNA Chips. Top. Curr. Chem. 2006, 261, 113-129.