Brain functional changes in rats administered with monosodium L-glutamate in the stomach

Annals of the New York Academy of Sciences

Volumn 1170, Issue , 2009, Pages 77-81

  Kondoh, Takashi ^a   Tsurugizawa, Tomokazu ^a   Torii, Kunio ^a  

^a AJINOMOTO CO INC   (Japan)

Author keywords

Brain activation; Energy homeostasis; Functional magnetic resonance imaging; Monosodium l glutamate; Obesity; Physiological function; Rat; Umami substance; Vagus nerve

Indexed keywords

AMINO ACID DERIVATIVE; GLUCOSE; GLUTAMATE SODIUM; RECEPTOR PROTEIN; SODIUM CHLORIDE;

AMYGDALOID NUCLEUS; BRAIN FUNCTION; BRAIN NUCLEUS; BRAIN REGION; CHEMORECEPTOR; CINGULATE GYRUS; CONFERENCE PAPER; FOREBRAIN; FUNCTIONAL ASSESSMENT; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HABENULA; HIPPOCAMPUS; HUMAN; HYPOTHALAMUS; IMAGE ANALYSIS; INSULA; INTESTINE MUCOSA; MOUTH CAVITY; NONHUMAN; NUCLEUS ACCUMBENS; POSTPRANDIAL STATE; PREOPTIC AREA; PUTAMEN; SENSORY NERVE; SIGNAL TRANSDUCTION; STIMULUS RESPONSE; STOMACH; TASTE DISCRIMINATION; VAGUS NERVE;

RATTUS;

EID: 68649088590     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.03884.x     Document Type: Conference Paper

References (22)

1. San Gabriel, A., T. Maekawa, H. Uneyama, et al. 2007. mGluR1 in the fundic glands of rat stomach. FEBS Lett. 581: 1119-1123.
2. Bezençon, C., J.I. Coutre & S. Damak. 2007. Tastesignaling proteins are coexpressed in solitary intestinal epithelial cells. Chem. Senses 32: 41-49.
3. Zhu, J.X., X.Y. Zhu, C. Owyang & Y. Li. 2001. Intestinal serotonin acts as a paracrine substance to mediate vagal signal transmission evoked by luminal factors in the rat. J. Physiol. 530: 431-442.
4. Jang, H.J. et al. 2007. Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. Proc. Natl. Acad. Sci. USA 104: 15069-15074.
5. Margolskee, R.F. et al. 2007. T1R3 and gustducin in gut sense sugars to regulate expression of Na+- glucose cotransporter 1. Proc. Natl. Acad. Sci. USA 104:15075-15080.
6. Niijima, A. 2000. Reflex effects of oral, gastrointestinal and hepatoportal glutamate sensors on vagal nerve activity. J. Nutr. 130: 971S-973S.
7. Uneyama, H., A. Niijima, A. SanGabriel & K. Torii. 2006. Luminal amino acid sensing in the rat gastric mucosa. Am. J. Physiol. Gastrointest. Liver Physiol. 291:G1163-G1170.
8. Liu, Y., J.H. Gao, H.L. Liu & P.T. Fox. 2000. The temporal response of the brain after eating revealed by functional MRI. Nature 405: 1058-1062.
9. Smeets, P.A. et al. 2006. Effect of satiety on brain activation during chocolate tasting in men and women. Am. J. Clin. Nutr. 83: 1297-1305.
10. Tsurugizawa, T., T. Kondoh & K. Torii. 2008. Forebrain activation induced by postoral nutritive substances in rats. Neuroreport 19: 1111-1115.
11. Kondoh, T. & K. Torii. 2008.MSGintake suppresses weight gain, fat deposition, and plasma leptin levels in male Sprague-Dawley rats. Physiol. Behav. 95: 135-144.
12. Young, V.R. & A.M. Ajami. 2000. Glutamate: an amino acid of particular distribution. J. Nutr. 130:892S-900S.
13. Reeds, P.J., D.G. Burrin, B. Stoll & F. Jahoor. 2000. Intestinal glutamate metabolism. J. Nutr. 130: 978S-982S.
14. Kondoh, T., M. Mori, T. Ono & K. Torii. 2000. Mechanisms of umami taste preference and aversion in rats. J. Nutr. 130: 966S-970S.
15. Steiner, J.E. 1987. What the neonate can tell us about umami. In Umami: A Basic Taste. Y. Kawamura & M.R.Kare, Eds.: 97-123. Marcel Dekker. New York.
16. Schiffman, S.S. 1998. Sensory enhancement of foods for the elderly with monosodium glutamate and flavors. Food Rev. Int. 14: 321-333.
17. Vasilevskaia, L.S., M.V. Rymshina & G.K. Shlygin. 1993. Effect of glutamate and combined with inosine monophosphate on gastric secretion. Vopr. Pitan. (3): 29-33.
18. Kochetchov, A.M., G.K. Shlygin, T.I. Loranskaia, L.S. Vasilevskaia & S.Iu. Kondrashev. 1992. The use of monosodium glutamate in the combined therapy of patients with atrophic gastritis. Vopr. Pitan. (5-6): 19-22.
19. Ohara, I., S.I. Otsuka & Y. Yugari. 1988. Cephalic phase response of pancreatic exocrine secretion in conscious dogs. Am. J. Physiol. 254: G424-G428.
20. Niijima, A., T. Togiyama & A. Adachi. 1990. Cephalic-phase insulin release induced by taste stimulus of monosodium glutamate (umami taste). Physiol. Behav. 48: 905-908.
21. Zai, H. et al. 2009. Monosodium L-glutamate added to a high-energy, high protein liquid diet promotes gastric emptying. Am. J. Clin. Nutr. 89: 431-435.
22. Smriga, M., H. Murakami, M. Mori & K. Torii. 2000. Use of thermal photography to explore the agedependent effect of monosodium glutamate, NaCl and glucose on brown adipose tissue thermogenesis. Physiol. Behav. 71: 403-407.