Short communication hepatoprotective property of thespesia populnea against carbon tetrachloride induced liver damage in rats

Journal of Basic and Clinical Physiology and Pharmacology

Volumn 20, Issue 2, 2009, Pages 169-178

  Yuvaraj, P ^a   Subramoniam, A ^b  

^a JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

^b Tropical Botanic Garden and Research Institute   (India)

Author keywords

carbon tetrachloride; hepatoprotection; liver damage; Thespesia populnea

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CARBON TETRACHLORIDE; PLANT EXTRACT; SILYMARIN; THESPESIA POPULNEA EXTRACT; UNCLASSIFIED DRUG;

ANGIOSPERM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; LIVER INJURY; LIVER PROTECTION; NONHUMAN; PLANT LEAF; PLANT STEM; RAT; THESPESIA POPULNEA;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CARBON TETRACHLORIDE; LIVER; MALE; MALVACEAE; PLANT EXTRACTS; RATS; RATS, WISTAR;

EID: 68549133289     PISSN: 07926855     EISSN: 21910286     Source Type: Journal    
DOI: 10.1515/JBCPP.2009.20.2.169     Document Type: Article

References (16)

1. Subramoniam, A, Pushpangadan, P. Development of phytomedicines for liver diseases. Indian J Pharmacol 1999; 31:166-75.
2. Anonymous. The Wealth of India. Publication and information Directorate (CSIR), New Delhi, 1995;223-75.
3. Sathyanarayana, T, Sarita, T, Balaji, M, Ramesh, A, Boini, MK. Anti-hyperglycemic and hypoglycemic effect of Thespesia populnca fruit in normal and alloxan-induced diabetes in rabbits. Saudi Pharmacol J 2004; 12:107-11.
4. Ilavarasan, R, Vasudevan, M, Anbazhagan, S, Venkataraman, S. Antioxidant activity of Thespesia populnea bark extracts against carbon tetrachloride-induced liver injury in rats. J Ethnopharmacol 2003; 87:227-30.
5. Shirwaikar, A, Kumar, AV, Krishnanand, BR, Sreenivasan, KK. Chemical investigation and antihepatotoxic activity of Thespesia populnea. Int J Pharmacogonosy 1995;33:305-10.
6. Vasudevan, M, Parle, M. Pharmacological actions of Thespesia populnea relevant to Alzheimer's disease. Phytomedicine 2006; 13:677-87.
7. Vasudevan, M, Gunnam, KK, Parle, M. Antinociceptive and antiinflammatory effects of Thespesia populnea bark extract. J Ethno-Pharmacol 2007; (2), 264-70.
8. Johnson, JI, Gandhidasan, R, Murugesan, R. Cytotoxicity and superoxide anion generation by some naturally occurring quinines. Free Radie Biol Med 1999; 26:1072-78.
9. Subramoniam, A, Evans, DA, Rajasekharan, S, Pushpangadan, P. Hepatoprotective activity of Trichopus zeylanicus extract against paracetamol-induced hepatic damage in rats. Indian J Exp Biol 1998; 36:385-9.
10. Ramellini, G., Meldolesi, J. Liver protection by Silymarin. In vitro effect on dissociated rat hepatocytes. Arzneim Forsch (Drug Res) 1976; 26:69–73.
11. James, G.W. and Pickering, R.W. The protective effect of novel compound RU 18492, on galactosamine-induced hepatotoxicity in the rat. Arzneimittel for-scung 1976; 26(12):2197-9.
12. Recknagel, RO, Giende, EA, Hruszkewycz, AM. In: Pryor EA, ed. Free radicals in biology. Vol. III. New York; Academic Press, 1976;97-132.
13. Mahendale, HM, Gupta, PK, Shalunkhe, DK. Hepatic Toxicity, vol. I. Delhi; Metropolitan Book, 1985;225-76.
14. Drotman, RB, Lowhom, GT. Serum enzymes as indicators of chemical induced liver damage. Drug ChemToxicol 1978;1:163-71.
15. nded. New York; Raven Press, 1989;599–628.
16. Singh, B, Saxena, A, Chandan, BK, Anand, KK, Suri, OP, Suri, KA, et al. Hepatoprotective activity of verbenalin on experimental liver damage in rodents. Fitoterapia 1998; 69:135-40.