Platelet hyperreactivity in response to on- and off-pump coronary artery bypass grafting

Journal of Extra-Corporeal Technology

Volumn 41, Issue 1, 2009, Pages 15-19

  Bochsen, Louise ^a   Rosengaard, Lisbeth Bredahl ^a   Nielsen, Allan Bybeck ^a   Steinbrüchel, Daniel A ^a   Johansson, Pär I ^a  

^a International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

Author keywords

Hypercoagulability; Off pump; On pump; Platelets; Thrombelastography

Indexed keywords

TRANEXAMIC ACID;

ADULT; AGED; CONFERENCE PAPER; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; ELECTIVE SURGERY; FEMALE; HIGH RISK PATIENT; HUMAN; HYPERCOAGULABILITY; MAJOR CLINICAL STUDY; MALE; MAXIMAL AMPLITUDE; OFF PUMP CORONARY SURGERY; PARAMETER; PATIENT MONITORING; PLATELET HYPERREACTIVITY; POSTOPERATIVE HEMORRHAGE; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; REFERENCE VALUE; REOPERATION; SURGICAL PATIENT; THROMBOELASTOGRAPHY; ARTICLE; COMPARATIVE STUDY; HEART STROKE VOLUME; INCIDENCE; INSTRUMENTATION; MIDDLE AGED; MORTALITY; PHYSIOLOGY; RISK ASSESSMENT; RISK FACTOR; THROMBOCYTE; THROMBOEMBOLISM;

ADULT; AGED; AGED, 80 AND OVER; BLOOD PLATELETS; CORONARY ARTERY BYPASS; CORONARY ARTERY BYPASS, OFF-PUMP; FEMALE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; REFERENCE VALUES; RISK ASSESSMENT; RISK FACTORS; STROKE VOLUME; THROMBELASTOGRAPHY; THROMBOEMBOLISM;

EID: 68549128700     PISSN: 00221058     EISSN: 29698960     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (19)

1. Hansen KH, Hughes P, Steinbruchel DA. Antithrombotic- and anticoagulation regimens in OPCAB surgery. A Nordic survey. Scand Cardiovasc J. 2005;39:369-74.
2. Khan NE, De SA, Mister R, et al. A randomized comparison of off-pump and on-pump multivessel coronary-artery bypass surgery. N Engl J Med. 2004;350:21-8.
3. Puskas JD, Williams WH, Duke PG, et al. Off-pump coronary artery bypass grafting provides complete revascularization with reduced myocardial injury, transfusion requirements, and length of stay: a prospective randomized comparison of two hundred unselected patients undergoing off-pump versus conventional coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2003;125:797-808.
4. Widimsky P, Straka Z, Stros P, et al. One-year coronary bypass graft patency: a randomized comparison between off-pump and on-pump surgery angiographic results of the PRAGUE-4 trial. Circulation. 2004;110:3418-23.
5. Casati V, Gerli C, Franco A, et al. Activation of coagulation and fibrinolysis during coronary surgery: on-pump versus off-pump techniques. Anesthesiology. 2001;95:1103-9. (Pubitemid 33043224)
6. Englberger L, Immer FF, Eckstein FS, Berdat PA, Haeberli A, Carrel TP. Off-pump coronary artery bypass operation does not increase procoagulant and fibrinolytic activity: preliminary results. Ann Thorac Surg. 2004;77:1560-6.
7. Güden M, Sanisoglu I, Sagbas E, Ergenoglu MU, Ozbek U, Akpinar B. Hemodilution during off-pump coronary artery bypass grafting: can we improve flow and reduce hypercoagulability? Heart Surg Forum. 2003;6:399-402.
8. Moller CH, Steinbruchel DA. Platelet function after coronary artery bypass grafting: is there a procoagulant activity after off-pump compared with on-pump surgery? Scand Cardiovasc J. 2003;37:149-53.
9. Nashef SA, Roques F, Michel P, Gauducheau E, Lemeshow S, Salamon R. European system for cardiac operative risk evaluation (EuroSCORE). Eur J Cardiothorac Surg. 1999;16:9-13.
10. Kurlansky PA. Is there a hypercoagulable state after off-pump coronary artery bypass surgery? What do we know and what can we do? J Thorac Cardiovasc Surg. 2003;126:7-10.
11. Paparella D, Galeone A, Venneri MT, et al. Activation of the coagulation system during coronary artery bypass grafting: comparison between on-pump and off-pump techniques. J Thorac Cardiovasc Surg. 2006;131:290-7.
12. Moor E, Blomback M, Silveira A, et al. Haemostatic function in patients undergoing coronary artery bypass grafting: peroperative perturbations and relations to saphenous vein graft closure. Thromb Res. 2000;98:39-49.
13. Lang T, von Depka M. Possibilities and limitations of thromboelastometry/thromboelastography. Hamostaseologie. 2007;26(Suppl 1):S21-9.
14. Samama CM, Thiry D, Elalamy I, et al. Perioperative activation of hemostasis in vascular surgery patients. Anesthesiology. 2001;94:74-8.
15. McCrath DJ, Cerboni E, Frumento RJ, Hirsh AL, Bennett-Guerrero E. Thromboelastography maximum amplitude predicts postoperative thrombotic complications including myocardial infarction. Anesth Analg. 2005;100:1576-83.
16. Bochsen L, Wiinberg B, Kjelgaard-Hansen M, Steinbruchel DA, Johansson PI. Evaluation of the TEG(R) platelet mapping assay in blood donors. Thromb J. 2007;5:3.
17. Gurbel PA, Bliden KP, Guyer K, et al. Platelet reactivity in patients and recurrent events post-stenting: results of the PREPARE POST-STENTING Study. J Am Coll Cardiol. 2005;46:1820-6.
18. Poston R, Gu J, Brown J, et al. Hypercoagulability affecting early vein graft patency does not exist after off-pump coronary artery bypass. J Cardiothorac Vasc Anesth. 2005;19:11-8.
19. Rocca B, Patrono C. Determinants of the interindividual vari ability in response to antiplatelet drugs. J Thromb Haemost. 2005;3:1597-602.