The Candida albicans histidine kinase Chk1p: Signaling and cell wall mannan

Fungal Genetics and Biology

Volumn 46, Issue 10, 2009, Pages 731-741

  Li, Dongmei ^a   Williams, David ^b   Lowman, Douglas ^b,c   Monteiro, Mario A ^d   Tan, Xuan ^d   Kruppa, Michael ^a   Fonzi, William ^a   Roman, Elvira ^e   Pla, Jesus ^e   Calderone, Richard ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b East Tennessee State University   (United States)

^c EASTMAN CHEMICAL COMPANY   (United States)

^d UNIVERSITY OF GUELPH   (Canada)

^e UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Candida albicans; Cek1; Histidine kinase; Mannan; Sho1; Signal transduction

Indexed keywords

ALCIAN BLUE; CONGO RED; MANNAN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN HISTIDINE KINASE;

ARTICLE; CANDIDA ALBICANS; CARBOHYDRATE SYNTHESIS; CELL WALL; CHEMOSENSITIVITY; CONTROLLED STUDY; DATA ANALYSIS; ENZYME PHOSPHORYLATION; FUNGAL CELL; FUNGAL STRAIN; FUNGUS GROWTH; FUNGUS MUTANT; GAS LIQUID CHROMATOGRAPHY; GENE CONSTRUCT; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STAINING; SYNTHESIS;

ANTIFUNGAL AGENTS; BENZENESULFONATES; CANDIDA ALBICANS; CELL WALL; CONGO RED; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; MAGNETIC RESONANCE SPECTROSCOPY; MANNANS; PROTEIN KINASES; SIGNAL TRANSDUCTION;

CANDIDA ALBICANS;

EID: 68549128492     PISSN: 10871845     EISSN: 10960937     Source Type: Journal    
DOI: 10.1016/j.fgb.2009.06.008     Document Type: Article

References (50)

1. Alex L., Korch C., Selitrenikoff C., and Simon M. COS1, a two-component histidine kinase that is involved in hyphal development in the opportunistic pathogen, Candida albicans. Proc. Natl. Acad. Sci. 95 (1998) 7069-7073
2. Alonso-Monge R., Roman E., Nombela C., and Pla J. The MAP kinase signal transduction network in Candida albicans. Microbiology 152 (2006) 905-912
3. Alonso-Monge R., Navarro-Garcia E., Roman E., Negredo B., Eisman C., Nombela C., and Pla J. The HOG1 MAP Kinase is essential in the oxidative stress response and chlamydospore formation in Candida albicans. Eukaryot. Cell 2 (2003) 351-361
4. Arana D.M., Alonso-Monge R., Du C., Calderone R., and Pla J. Differential susceptibility of mitogen-activated protein kinase pathways to oxidative-mediated killing by phagocytes in the fungal pathogen Candida albicans. Cell Microbiol. 9 (2007) 1647-1659
5. Arana D.M., Nombela C., Alonso R., and Pla J. The Pbs2 MAP kinase kinase is essential for the oxidative stress response in the fungal pathogen Candida albicans. Microbiology 151 (2005) 1033-1049
6. Bahn Y., Kojima K., Cox G., and Heitman J. A unique fungal two-component system regulates stress responses, drug sensitivity, sexual development and virulence of Cryptococcus neoformans. Mol. Biol. Cell 7 (2006) 3122-3135
7. Beier D., and Gross R. Regulation of bacterial virulence by two-component systems. Curr. Opin. Microbiol. 9 (2006) 143-152
8. Bernhardt J., Herman D., Sheridan M., and Calderone R. Adherence and invasion studies of Candida albicans strains, using in vitro models of esophageal candidiasis. J. Infect. Dis. 184 (2001) 1170-1175
9. Calera J.A., Zhao X.-J., and Calderone R. Defective hyphal formation and avirulence caused by a deletion of the CSSK1 response regulator gene in Candida albicans. Infect. Immun. 68 (2000) 518-525
10. Calera J.A., Herman D., and Calderone R. Identification of YPD1, a gene of Candida albicans which encodes a two-component phospho-histidine intermediate protein. Yeast 16 (2000) 1053-1059
11. Calera J.A., Choi G., and Calderone R. Identification of a putative histidine kinase two-component phosphorelay gene (CaHK1) in Candida albicans. Yeast 14 (1998) 665-674
12. Calera J.A., and Calderone R. Flocculation of hyphae is associated with a deletion in the putative CaHK1 two-component histidine kinase gene of Candida albicans. Microbiology 145 (1999) 1431-1442
13. Calera J.A., Zhao X.-J., Sheridan M., and Calderone R. Avirulence of Candida albicans CaHK1 mutants in a murine model of hematogenously disseminated candidiasis. Infect. Immun. 67 (1999) 4280-4284
14. Chauhan N., and Calderone R. Two-component signal transduction proteins as potential drug targets in medically important fungi. Infect. Immun. 76 (2008) 4795-4803
15. Chauhan N., Inglis D., Pla J., Li D., Calera J., and Calderone R. The SSK1 of Candida albicans is associated with oxidative stress adaptation and cell wall biosynthesis. Eukaryot. Cell 2 (2003) 1018-1024
16. Chauhan N., Latge J.-P., and Calderone R. Signaling and oxidant adaptation in Candida albicans and Aspergillus fumigatus. Nature Microbiol. Rev. 4 (2006) 435-444
17. Chen J., Chen J., Lane S., and Liu H. A conserved mitogen-activated protein kinase pathway is required for mating in Candida albicans. Mol. Microbiol. 46 (2002) 1335-1344
18. Ciucanu K., and Kerek F. A simple and rapid method for the permethylation of carbohydrates. Carbohydrate Res. 131 (1984) 209-217
19. Csank C., Schroppel K., Leberer E., Harcus D., Mohamed O., Meloche S., Thomas D., and Whiteway M. Roles of the Candida albicans mitogen-activated protein kinase homolog, Cek1p, in hyphal development and systemic candidiasis. Infect. Immun. 66 (1998) 2713-2721
20. Dean N. Yeast glycosylation mutants are sensitive to aminoglycosides. Proc. Nat. Acad. Sci. 92 (1995) 1287-1291
21. Eisman B., Alonso-Monge R., Roman E., Arana D., Nombela C., and Pla J. The Cek1 and Hog1 mitogen-activated protein kinases play complementary roles in cell wall biogenesis and chlamydospore formation in the fungal pathogen Candida albicans. Eukaryot. Cell 5 (2006) 347358
22. Fonzi W.A., and Irwin M. Isogenic strain construction and gene mapping in Candida albicans. Genetics 134 (1993) 717-728
23. Gimenez-Abian M., Bernabe M., Leal J., Jimenez-Barbero J., and Prieto A. Structure of a galactomannan isolated from the cell wall of the fungus Lineolata rhizophorae. Carbohydrate Res. 342 (2007) 2599-2603
24. Herrero A., Ucceletti D., Hirschberg C., Dominguez A., and Abeijon C. The golgi GDPase of the fungal pathogen Candida albicans affects morphogenesis, glycosylation, and cell wall properties. Eukaryot. Cell 1 (2002) 420-431
25. Hohmann S. Osmotic stress signaling and osmoadaptation in yeasts. Microbiol. Mol. Biol. Rev. 66 (2002) 300-372
26. Kath F., and Kulicke W.M. Polymer analytical characterization of glucan and mannan from yeast Saccharomyces cerevisiae. Die Angewandte Makromolekulare Chemie 268 (1999) 69-80
27. 1 H Nuclear magnetic resonance chemical shifts of the inner α-1,6-linked mannose residues substituted by a side chain. Arch. Biochem. Biophys. 341 (1997) 70-74
28. Kocourek J., and Ballou C. Method for fingerprinting yeast cell wall mannan. J. Bacteriol. 100 (1969) 1175-1181
29. Kruppa M., and Calderone R. Two-component signal transduction in human fungal pathogens. FEMS Yeast Res. 6 (2006) 149-159
30. Kruppa M., Jabra-Rizk M., Meiller T., and Calderone R. The histidine kinases of Candida albicans: regulation of cell wall mannan biosynthesis. FEMS Yeast Res. 4 (2004) 409-416
31. Kruppa M., Krom B., Cihlar R., and Calderone R. The histidine kinase Chk1p regulates quorum sensing in Candida albicans. Eukaryot. Cell 3 (2004) 1062-1065
32. Kruppa M., Goins T., Cutler J., Lowman D., Williams D., Chauhan N., Menon V., Singh P., Li D., and Calderone R. The role of the Candida albicans histidine kinase (CHK1) in the regulation of cell wall mannan and glucan synthesis. FEMS Yeast Res. 3 (2003) 289-299
33. Li D., Gurskova V., Sheridan M., and Calderone R. Studies on the regulation of the two-component histidine kinase gene CHK1 in Candida albicans using the heterologous lacZ reporter gene. Microbiology 150 (2004) 3305-3313
34. Li D., Bernhardt J., and Calderone R. Temporal expression of the Candida albicans genes CHK1 and CSSK1, adherence and morphogenesis in a model of reconstituted human esophageal candidiasis. Infect. Immun. 70 (2002) 1558-1565
35. Masuoka J. Surface glycans of Candida albicans and other pathogenic fungi: physiological roles, clinical uses, and experimental challenges. Clin. Microbiol. Rev. 17 (2004) 281-310
36. Millet C., Janbon G., Delplace F., Ibata-Ombetta S., Gaillardin C., Strecker G., Jouault P., and Poulain D. Inactivation of CaMIT1 inhibits Candida albicans phospholipomannan β-mannosylation, reduces virulence, and alters cell wall protein β-mannosylation. J. Biol. Chem. 279 (2004) 47952-47960
37. Mueller A., Raptis J., Rice P., Kalbfleisch H., Stout D., Ensley H., Browder W., and Williams D.L. The influence of glucan polymer structure and solution conformation on binding to (1→3)-β-D-glucan receptors in a human monocyte-like cell line. Glycobiology 10 (2000) 339-355
38. Nagahashi S., Mio T., Ono M., Yamada-Okabe T., Arisawa M., Bussey H., and Yamada-Okabe H. Isolation of CaSLN1 and CaNIK1, the genes for osmosensing histidine kinase homologues, from the pathogenic fungus, Candida albicans. Microbiology 144 (1998) 425-432
39. Nemecek J., Wuthrich M., and Klein B.S. Global control of dimorphism and virulence in fungi. Science 312 (2006) 583-588
40. Novarro-Garcia F., Eisman B., Fluza S., Nombela C., and Pla J. The MAP kinase Mkc1p is activated under different stress conditions in Candida albicans. Microbiology 151 (2005) 2737-2749
41. Roman E., Nombela C., and Pla J. The Sho1p adaptor protein links oxidative stress to morphogenesis and cell wall biosynthesis in the fungal pathogen Candida albicans. Mol. Cell Biol. 25 (2005) 10611-10627
42. SanJose C., Alonso-Monge R., Perez-Diaz R., Pla J., and Nombela C. The mitogen-activated protein kinase HOG1 gene controls glycerol accumulation in the pathogenic fungus Candida albicans. J. Bacteriol. 178 (1996) 5850-5852
43. Sawardeker J.S., Sloneker J., and Jeanes A. Quantitative determination of monosaccharides as their alditol acetates by gas liquid chromatography. Anal Chem. 37 (1967) 1602-1604
44. Selitrennikoff C.P., Alex L., Miller T., Clemons K., Simon M., and Stevens D. COS1, a putative two-component histidine kinase of Candida albicans, is an in vivo virulence factor. Med. Mycol. 39 (2001) 69-75
45. Shibata N., Kobayashi H., Okawa Y., and Suzuki S. Existence of novel β-1,2 linkage-containing side chain in the mannan of Candida lusitaniae, antigenically related to Candida albicans serotype A. Eur. J. Biochem. 270 (2003) 2565-2575
46. Shibata N., Ikuta K., Imai T., Satoh Y., Satoh R., Suzuki A., Koima C., Kobayashi H., Hisamichi K., and Suzuki S. Existence of branched side chains in the cell wall mannan of the pathogenic yeast, Candida albicans. J. Biol. Chem. 270 (1995) 1113-1122
47. Srikantha T., Tsai L., Daniels K., Enger L., Kingley K., and Soll D. The two-component hybrid kinase regulator CaNIK1 of Candida albicans. Microbiology 144 (1998) 2715-2729
48. Trinel P.-A., Maes E., Zanetta J.-P., Delplace F., Coddeville B., Jouault T., Strecker G., and Poulain D. Candida albicans phospholipomannan, a new member of the fungal mannose inositol phosphoceramide family. J. Biol. Chem. 277 (2002) 37260-37271
49. Torosantucci A., Chiani P., DeBernardis F., Cassone A., Calera J., and Calderone R. Deletion of the two-component histidine kinase gene (CHK1) of Candida albicans contributes to enhanced growth inhibition and killing by human neutrophils in vitro. Infect. Immun. 70 (2002) 985-987
50. Yamada-Okabe T., Mio T., Ono N., Kashima Y., Matsui M., Arisawa M., and Yamada-Okabe H. Roles of three histidine kinase genes in hyphal development and virulence of the pathogenic fungus, Candida albicans. J. Bacteriol. 181 (1999) 7243-7247