Visual neurophysiological dysfunction in infants exposed to hydroxychloroquine in utero

Acta Paediatrica, International Journal of Paediatrics

Volumn 98, Issue 9, 2009, Pages 1500-1503

  Renault, F ^a,b   Flores Guevara, R ^b,c   Renaud, C ^b   Richard, P ^b   Vermersch, A I ^b   Gold, F ^b  

^a ARMAND TROUSSEAU HOSPITAL   (France)

^b ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^c INSERM   (France)

Author keywords

Electroretinogram; Foetus; Hydroxychloroquine; Infant; Visual evoked potentials

Indexed keywords

HYDROXYCHLOROQUINE;

ARTICLE; B WAVE; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTRORETINOGRAPHY; EVOKED VISUAL RESPONSE; FRANCE; HEALTH SURVEY; HUMAN; INFANT; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS; TREATMENT DURATION; VISUAL DISORDER; VISUAL NEUROPHYSIOLOGICAL DYSFUNCTION; VISUAL STIMULATION;

ANTIRHEUMATIC AGENTS; CONNECTIVE TISSUE DISEASES; ELECTRORETINOGRAPHY; EVOKED POTENTIALS, VISUAL; FEMALE; HUMANS; HYDROXYCHLOROQUINE; INFANT; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RETINA; VISION DISORDERS; VISUAL PATHWAYS;

EID: 68549118920     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1111/j.1651-2227.2009.01379.x     Document Type: Article

References (26)

1. Parke A, West B. Hydroxychloroquine in pregnant patients with systemic lupus erythematosus. J Rheumatol 1996 23 : 1715 8.
2. Levy RA, Vilela VS, Cataldo MJ, Ramos RC, Duarte JL, Tura BR, et al. Hydroxychloroquine (HCQ) in lupus pregnancy: double-blind and placebo-controlled study. Lupus 2001 10 : 401 4.
3. Ingster-Moati I, Crochet M, Manchon E, Anquetil D, Lestrade C, Jacob A, et al. [Analysis of 925 patients on long-term hydroxychloroquine or chloroquine treatment: results of ophthalmological screening]. J Fr Ophtalmol 2004 27 : 367 73.
4. Costedoat-Chalumeau N, Amoura Z, Duhaut P, Huong DL, Sebbough D, Wechsler B, et al. Safety of hydroxychloroquine in pregnant patients with connective tissue diseases. Arthritis Rheum 2003 48 : 3207 11.
5. Clowse MEB, Magder L, Witter F, Petri M. Hydroxychloroquine in lupus pregnancy. Arthritis Rheum 2006 54 : 3640 7.
6. Klinger G, Morad Y, Westall CA, Laskin C, Spitzer KA, Koren G, et al. Ocular toxicity and antenatal exposure to chloroquine or hydroxychloroquine for rheumatic diseases. Lancet 2001 358 : 524 5.
7. Motta M, Tincani A, Faden D, Zinzini E, Lojacono A, Marchesi A, et al. Follow-up of infants exposed to hydroxychloroquine given to mothers during pregnancy and lactation. J Perinatol 2005 25 : 86 9.
8. Renaud C, de Montgolfier I, Vautier-Brouzes D, Costedoat-Chalumeau N, Lapillonne A, Gold F. [Perinatal consequences of maternal connective tissue diseases: a prospective study of 73 cases]. Arch Pediatr 2006 13 : 1386 90.
9. Flores-Guevara R, Renault F, Ostré C, Richard P. Maturation of the electroretinogram in children: stability of the amplitude ratio a/b. Electroencephalogr Clin Neurophysiol 1996 100 : 422 7.
10. Laget P, Flores-Guevara R, D'Allest AM, Ostré C, Raimbault J, Mariani J. [Maturation of visually evoked potentials in the normal child]. Electroenceph clin Neurophysiol 1977 43 : 732 44.
11. Cimaz R, Brucato A, Meregalli E, Muscara M, Sergi P. Electroretinograms of children born to mothers treated with hydroxychloroquine during pregnancy and breast-feeding: comment on the article by Costedoat-Chalumeau et al. Arthritis Rheum 2004 50 : 3056 7.
12. Costedoat-Chalumeau N, Amoura Z, Sebbough D, Piette JC. Letter to the editor (reply to Cimaz and colleagues). Arthritis Rheum 2004 50 : 3057 8.
13. Marmor MF, Carr RE, Easterbrook M, Farjo AA, Mieler WF for the American Academy of Ophthalmology. Recommendations on screening for chloroquine and hydroxychloroquine retinopathy. Ophthalmology 2002 109 : 1377 82.
14. Ingster-Moati I, Crochet M, Albuisson E. [Electroretinogram "b" wave varies with the posology of the antimalarial treatment]. J Fr Ophtalmol 2004 27 : 1007 12.
15. Inernational Standardization Committee. Standard for clinical electroretinography. Arch Ophthalmol 1989 107 : 816 9.
16. Berezovsky A, Moraes NS, Nusinowitz S, Salomao SR. Standard full-field electroretinography in healthy preterm infants. Doc Ophthalmol 2003 107 : 243 9.
17. Lai TY, Chan WM, Li H, Lai RY, Lam DS. Multifocal electroretinographic changes in patients receiving hydroxychloroquine therapy. Am J Ophthalmol 2005 140 : 794 807.
18. Boya P, Gonzales-Polo RA, Poncet D, Andreau K, Vieira HL, Roumier T, et al. Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine. Oncogene 2003 22 : 3927 36.
19. Tomita T, Yanagida T. Origins of the ERG waves. Brain Res 1981 21 : 1703 7.
20. Miller R, Dowling J. Intracellular responses of the Müller (glial) cells of mudpuppy retina: their relation to the b-wave of the electroretinogram. J Neurophysiol 1970 33 : 323 41.
21. Yonemura D, Kawasaki K. Electrophysiological study on activities of neuronal and non-neuronal retinal elements in man with reference to its clinical application. Jpn J Ophthalmol 1978 22 : 1 19.
22. Wachtmeister L. Oscillatory potentials in the retina: what do they reveal. Prog Retin Eye Res 1998 17 : 485 521.
23. Ogden T. Clinical electrophysiology. In : Ryan S, editor. Retina. St Louis : Mosby, 1989 : pp. 285 96.
24. Costedoat-Chalumeau N, Amoura Z, Aymard G, Le TH, Wechsler B, Vauthier D, et al. Evidence of transplacental passage of hydroxychloroquine in humans. Arthritis Rheum 2002 46 : 1123 4.
25. Nation RL, Hackett LP, Dusci LJ, Ilett KF. Excretion of hydroxychloroquine in human milk. Br J Clin Pharmacol 1984 17 : 368 9.
26. Ostensen M, Brown ND, Chiang PK, Aarbakke J. Hydroxychloroquine in human breast milk. Eur J Clin Pharmacol 1985 28 : 357.