Comparison of hypotensive and hypolipidemic effects of Catharanthus roseus leaves extract with atenolol on adrenaline induced hypertensive rats

Pakistan Journal of Pharmaceutical Sciences

Volumn 22, Issue 3, 2009, Pages 267-271

  Ara, Naznin ^a   Rashid, Mamunur ^a   Amran, M D Shah ^b  

^a UNIVERSITY OF RAJSHAHI   (Bangladesh)

^b UNIVERSITY OF DHAKA   (Bangladesh)

Author keywords

Adrenaline; Antihypertensive; Atenolol; Catharanthus roseus; Hypertension

Indexed keywords

ADRENALIN; ATENOLOL; CATHARANTHUS ROSEUS EXTRACT; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; LIPID; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG MECHANISM; GLUCOSE BLOOD LEVEL; HEART WEIGHT; HYPERTENSION; MORNING DOSAGE; NONHUMAN; PLANT LEAF; RAT; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; BLOOD; BLOOD PRESSURE; CATHARANTHUS; CHEMICALLY INDUCED DISORDER; CHEMISTRY; COMPARATIVE STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; DRUG EFFECT; HEART; HYPERLIPIDEMIA; INTRAPERITONEAL DRUG ADMINISTRATION; METABOLISM; ORGAN SIZE; PHYTOTHERAPY;

ANIMALS; ANTIHYPERTENSIVE AGENTS; ANTILIPEMIC AGENTS; ATENOLOL; BLOOD GLUCOSE; BLOOD PRESSURE; BODY WEIGHT; CATHARANTHUS; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; EPINEPHRINE; HEART; HYPERLIPIDEMIAS; HYPERTENSION; INJECTIONS, INTRAPERITONEAL; LIPIDS; ORGAN SIZE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; RATS;

EID: 68549111226     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Amran MS, Hashmito K and Homma N (2004). Effects of sodium-calcium exchange inhibitors. J. Pharmacol. Exp. Therap., 310: 83-89.
2. Antia BS and Okokon JE (2005). Effect of leaf juice of Catharanthus roseus Linn on cholesterol, triglyceride and lipoproteins levels in normal rats. Indian Journal of Pharmacology, 37: 401-402.
3. st edition, pp.68-98.
4. st edition, pp.95-107.
5. Boesen EI, Andersion WP and Michelle MK (2005). Role of endothelin in noradrenaline-induced hypertension in rats. Journal of Hypertension, 23(5): 987-993. (Pubitemid 40637917)
6. st edition, pp.67-100.
7. Gilani AH, Aftab K, Suria A, Siddiqui S, Salem R, Siddiqui BS and Faizi S (1984). Pharmacological studies on hypotensive and spasmolytic activities of pure compounds from Moringa oleifera. Phytotherapy Research, 8(2): 7-91.
8. th edition, Pergamon Press, New York, Vol.1&2, pp.749-806.
9. Kirtikar KR and Basu K (1984). Indian Medicinal Plants, Vol.1, pp.677-681.
10. Momin A (1987). Role of indigenous medicine in primary health care. In: Proceedings of First International Seminar on Unani Medicine. New Delhi, India, p.54.
11. Perry LM and Metzger J (1980). Medicinal Plants of SE Asia: Attributed Properties and Uses. Cambridge, Massachusetts and London, The MIT Press, pp.23-148.
12. Siddiqui S and Khan M I (1968). Pharmacological Study of Moringa pterygosperma. Central Laboratories, Pakistan Council of Scientific and Industrial Research, pp.268-272.
13. Srinivas N, Murthy KB, Srinivas DL and Ravindra BS (2003). The juice of fresh leaves of Catharanthus roseus Linn. reduces blood glucose in normal and alloxan diabetic rabbits. BMC Complement Altern Med. 3: 4.
14. Yuki S, Toshio O, Mamunur R, Takashi N, Kaoru H, Takafumi N, Kenichi W, Akio M and Mikio N (2002). Effects of chronic administration of sarpogrelate on systolic Blood Pressure on spontaneously hypertensive rats: comparison with Quinapril, pharmacology. International Journal of Experimental and Clinical Pharmacology. 64: 71-75.