Trends in the postmortem diagnosis of opportunistic invasive fungal infections in patients with AIDS: A retrospective study of 1,630 autopsies performed between 1984 and 2002

American Journal of Clinical Pathology

Volumn 132, Issue 2, 2009, Pages 221-227

  Antinori, Spinello ^a   Nebuloni, Manuela ^a   Magni, Carlo ^a   Fasan, Marco ^a   Adorni, Fulvio ^b   Viola, Anita ^a   Corbellino, Mario ^a   Galli, Massimo ^a   Vago, Gianluca ^a   Parravicini, Carlo ^a   Ridolfo, Anna Lisa ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b INSTITUTE OF BIOMEDICAL TECHNOLOGIES   (Italy)

Author keywords

Autopsy; Cryptococcosis; Fungal infections; HAART; Highly active antiretroviral therapy; Histoplasmosis; HIV AIDS; Pneumocystosis

Indexed keywords

ADULT; AGED; AIDS RELATED COMPLEX; ARTICLE; ASPERGILLOSIS; AUTOPSY; CAUSE OF DEATH; CRYPTOCOCCOSIS; DIAGNOSTIC ERROR; FEMALE; HISTOPLASMOSIS; HUMAN; INVASIVE CANDIDIASIS; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MORTALITY; MUCORMYCOSIS; MYCOSIS; OPPORTUNISTIC INFECTION; PNEUMOCYSTOSIS; PREVALENCE; PRIORITY JOURNAL;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADULT; AGED; AIDS-RELATED OPPORTUNISTIC INFECTIONS; AUTOPSY; DIAGNOSIS; FEMALE; HUMANS; IMMUNOCOMPROMISED HOST; MALE; MIDDLE AGED; MYCOSES; RETROSPECTIVE STUDIES;

EID: 68549107935     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/AJCPRAAE8LZ7DTNE     Document Type: Article

References (40)

1. McNeil MM, Nash SL, Hajjeh RA, et al. Trends in mortality due to invasive mycotic diseases in the United States, 1980-1997. Clin Infect Dis. 2001;33:641-647.
2. Phair J, Muñoz A, Detels R, et al, for the Multicenter AIDS Cohort Study Group. The risk of Pneumocystis carinii pneumonia among men infected with human immunodeficiency virus type 1. N Engl J Med. 1990;322:161-165.
3. Chuck SL, Sande MA. Infections with Cryptococcus neoformans in the acquired immunodeficiency syndrome. N Engl J Med. 1989;321:794-799.
4. Wheat LJ, Connolly-Stringfield PA, Baker RL, et al. Disseminated histoplasmosis in the acquired immune deficiency syndrome: clinical findings, diagnosis and treatment, and review of the literature. Medicine. 1990;69:361-374.
5. Burckhardt B, Sendi P, Pfluger D, et al. Rare AIDS-defining diseases in the Swiss HIV Cohort Study. Eur J Clin Microbiol Infect Dis. 1999;18:399-402.
6. Pursell KJ, Telzak EE, Armstrong D. Aspergillus species colonization and invasive disease in patients with AIDS. Clin Infect Dis. 1992;14:141-148.
7. Kaplan JE, Hanson D, Dworkin MS, et al. Epidemiology of human immunodeficiency virus-associated opportunistic infections in the United States in the era of highly active antiretroviral therapy. Clin Infect Dis. 2000;30(suppl 1):S5-S14.
8. Chamilos G, Luna M, Lewis RE, et al. Invasive fungal infections in patients with hematologic malignancies in a tertiary care cancer center: an autopsy study over a 15-year period (1989-2003). Haematologica. 2006;91:986-989.
9. Sinkó J, Csomor J, Nikolova R, et al. Invasive fungal disease in allogeneic hematopoietic stem cell transplant recipients: an autopsy-driven survey. Transpl Infect Dis. 2008;10:106-109.
10. Centers for Disease Control and Prevention. Revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. MMWR Morb Mortal Wkly Rep. 1993;41:1-17.
11. Goldman L, Sayson R, Robbins S, et al. The value of the autopsy in three medical eras. N Engl J Med. 1983;308:1000-1005.
12. Masliah E, DeTeresa RM, Mallory ME, et al. Changes in pathological findings at autopsy in AIDS cases for the last 15 years. AIDS. 2000;14:69-74.
13. Klatt EC, Nichols L, Noguchi TT. Evolving trends revealed by autopsies of patients with the acquired immunodeficiency syndrome. Arch Pathol Lab Med. 1994;118:884-890.
14. Afessa B, Green W, Chiao J, et al. Pulmonary complications of HIV infection: autopsy findings. Chest. 1998;113:1225-1229.
15. Morris A, Lundgren JD, Masur H, et al. Current epidemiology of Pneumocystis pneumonia. Emerg Infect Dis. 2004;10:1713-1720.
16. Cury PM, Pulido CF, Furtado VMG, et al. Autopsy findings in AIDS patients from a reference hospital in Brazil: analysis of 92 cases. Pathology. 2003;199:811-814.
17. van Elden LJ, Walenkamp AM, Lipovsky MM, et al. Declining number of patients with cryptococcosis in the Netherlands in the era of highly active antiretroviral therapy. AIDS. 2000;14:2787-2800.
18. Afessa B, Greaves W, Green W, et al. Autopsy findings in HIV-infected inner-city patients. J Acquir Immune Def Syndr. 1992;5:132-136.
19. Markowitz GS, Concepcion L, Factor SM, et al. Autopsy patterns of disease among subgroups of an inner-city Bronx AIDS population. J Acquir Immune Def Syndr Hum Retrovirol. 1996;13:48-54.
20. Antinori S, Radice A, Galimberti L, et al. The role of cryptococcal antigen assay in diagnosis and monitoring of cryptococcal meningitis. J Clin Microbiol. 2005;43:5828-5829.
21. Lortholary O, Meyohas MC, Dupont B, et al, for the French Cooperative Study Group on Aspergillosis in AIDS. Invasive aspergillosis in patients with acquired immunodeficiency syndrome: report of 33 cases. Am J Med. 1993;95:177-187.
22. Maertens J, Theunissen K, Lodewyck T, et al. Advances in the serological diagnosis of invasive Aspergillus infections in patients with haematological disorders. Mycoses. 2007;50(suppl 1):2-17.
23. Kami M, Tanaka Y, Kanda Y, et al. Computed tomographic scan of the chest, latex agglutination test and plasma (1AE3)-beta-D-glucan assay in early diagnosis of invasive pulmonary aspergillosis: a prospective study of 215 patients. Haematologica. 2000;85:745-752.
24. Hui AN, Koss MN, Meyer PR. Necropsy findings in acquired immunodeficiency syndrome: a comparison of premortem diagnosis with postmortem findings. Hum Pathol. 1984;15:670-676.
25. Reichert CM, O'Leary TJ, Levens DJ, et al. Autopsy pathology in the acquired immune deficiency syndrome. Am J Pathol. 1983;112:357-382.
26. Wilkes MS, Fortin AH, Felix JC, et al. Value of necropsy in acquired immunodeficiency syndrome. Lancet. 1988;ii:85-88.
27. Welch K, Finkbeiner W, Alpers CE, et al. Autopsy findings in the acquired immunodeficiency syndrome. JAMA. 1984;252:1152-1159.
28. Launay O, Lortholary O, Bouges-Michel C, et al. Candidemia: a nosocomial complication in adults with late stage AIDS. Clin Infect Dis. 1998;26:1134-1141.
29. Hofman P, Saint-Paul MC, Battaglione V, et al. Autopsy findings in the acquired immunodeficiency syndrome (AIDS): a report of 395 cases from the South of France. Pathology. 1999;195:209-217.
30. Antinori S, Magni C, Nebuloni M, et al. Histoplasmosis among human immunodeficiency virus-infected people in Europe: report of 4 cases and review of the literature. Medicine. 2006;85:22-36.
31. Boumis E, Chinello P, Conte A, et al. Rhino-orbital zygomycosis secondary to diabetic ketoacidosis in an HIV-positive patient: case report and literature review. AIDS. 2006;20:136-138.
32. Besson C, Jubault V, Viard JP, et al. Ketoacidosis associated with protease inhibitor therapy. AIDS. 1998;12:1399-1400.
33. Crum-Cianflone N, Hullsiek KH, Marconi V, et al. Trends in the incidence of cancers among HIV-infected persons and the impact of antiretroviral therapy: a 20-year cohort study. AIDS. 2009;23:41-50.
34. Loenen WA, Bruggeman CA, Wiertz EJ. Immune evasion by human cytomegalovirus: lessons in immunology and cell biology. Semin Immunol. 2001;13:41-49.
35. Webster A, Lee CA, Cook DG, et al. Cytomegalovirus infection and progression towards AIDS in haemophiliacs with human immunodeficiency virus infection. Lancet. 1989;2:63-66.
36. Einsele H, Hebart H, Kauffmann-Schneider C, et al. Risk factors for treatment failures in patients receiving PCR-based preemptive therapy for CMV infection. Bone Marrow Transplant. 2000;25:757-763.
37. Bonds LA, Gaido L, Woods JE, et al. Infectious diseases detected at autopsy at an urban public hospital, 1996-2001. Am J Clin Pathol. 2003;119:866-872.
38. Shojania KG, Burton EC. The vanishing nonforensic autopsy. N Engl J Med. 2008;358:873-875.
39. Schable B, Chu SY. Autopsy rates among patients reported with AIDS [letter]. Am J Public Health. 1994;84:1695-1696.
40. Schwarze EW. The significance of the autopsy: now and in the future [in German]. Verh Dtsch Ges Pathol. 2001;85:118-131.