Epigenomics in psychiatry

Neuropsychobiology

Volumn 60, Issue 1, 2009, Pages 2-4

  Kato, Tadafumi ^a  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

Bipolar disorder; Depression; DNA methylation; Epigenetics; Histone modification; Schizophrenia

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; HISTONE DEACETYLASE 5; IMIPRAMINE; VALPROIC ACID;

AUTOPSY; BRAIN REGION; DNA METHYLATION; DNA SEQUENCE; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; EPIGENETICS; FERTILIZATION; GAMETOGENESIS; GENE CONTROL; HUMAN; MEMORY; MENTAL DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHORT SURVEY; UPREGULATION;

ENVIRONMENT; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HUMANS; MENTAL DISORDERS; MUTATION;

EID: 68549107923     PISSN: 0302282X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000234810     Document Type: Short Survey

References (19)

1. Hashimoto R, Hattori S, Chiba S, Yagasaki Y, Okada T, Kumamaru E, Mori T, Nemoto K, Tanii H, Hori H, Noguchi H, Numakawa T, Ohnishi T, Kunugi H: Susceptibility genes for schizophrenia. Psychiatry Clin Neurosci 2006; 60(suppl 1):S4-S10.
2. Kato T: Molecular genetics of bipolar disorder and depression. Psychiatry Clin Neurosci 2007; 61: 3-19.
3. Petronis A, Gottesman II, Crow TJ, DeLisi LE, Klar AJ, Macciardi F, McInnis MG, Mc- Mahon FJ, Paterson AD, Skuse D, Sutherland GR: Psychiatric epigenetics: A new focus for the new century. Mol Psychiatry 2000; 5: 342-346.
4. Ushijima T, Watanabe N, Okochi E, Kaneda A, Sugimura T, Miyamoto K: Fidelity of the methylation pattern and its variation in the genome. Genome Res 2003; 13: 868-874.
5. Kato T, Iwamoto K, Kakiuchi C, Kuratomi G, Okazaki Y: Genetic or epigenetic difference causing discordance between monozygotic twins as a clue to molecular basis of mental disorders. Mol Psychiatry 2005; 10: 622-630.
6. Ushijima T: Epigenetic field for cancerization. J Biochem Mol Biol 2007; 40: 142-150.
7. Bird A: DNA methylation patterns and epigenetic memory. Genes Dev 2002; 16: 6-21.
8. Siegmund KD, Connor CM, Campan M, Long TI, Weisenberger DJ, Biniszkiewicz D, Jaenisch R, Laird PW, Akbarian S: DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. PLoS ONE 2007; 2:e895.
9. Kaffman A, Meaney MJ: Neurodevelopmental sequelae of postnatal maternal care in rodents: Clinical and research implications of molecular insights. J Child Psychol Psychiatry 2007; 48: 224-244.
10. Lillycrop KA, Phillips ES, Jackson AA, Hanson MA, Burdge GC: Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J Nutr 2005; 135: 1382-1386.
11. Wyrwoll CS, Mark PJ, Waddell BJ: Developmental programming of renal glucocorticoid sensitivity and the renin-angiotensin system. Hypertension 2007; 50: 579-584.
12. Weaver IC, Cervoni N, Champagne FA, D'Alessio AC, Sharma S, Seckl JR, Dymov S, Szyf M, Meaney MJ: Epigenetic programming by maternal behavior. Nat Neurosci 2004; 7: 847-854.
13. Francis D, Diorio J, Liu D, Meaney MJ: Nongenomic transmission across generations of maternal behavior and stress responses in the rat. Science 1999; 286: 1155-1158.
14. Champagne FA, Weaver IC, Diorio J, Dymov S, Szyf M, Meaney MJ: Maternal care associated with methylation of the estrogen receptor- alpha1b promoter and estrogen receptoralpha expression in the medial preoptic area of female offspring. Endocrinology 2006; 147: 2909-2915.
15. McGowan PO, Sasaki A, D'Alessio AC, Dymov S, Labonté B, Szyf M, Turecki G, Meaney MJ: Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci 2009;12: 342-348.
16. Nibuya M, Morinobu S, Duman RS: Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J Neurosci 1995; 15: 7539-7547.
17. Tsankova NM, Kumar A, Nestler EJ: Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures. J Neurosci 2004; 24: 5603-5610.
18. McGowan PO, Kato T: Epigenetics in mood disorders. Environ Health Prev Med 2008; 13:16-24.
19. Ptak C, Petronis A: Epigenetics and complex disease: from etiology to new therapeutics. Annu Rev Pharmacol Toxicol 2008; 48: 257-276.