Wall-to-lumen ratio of retinal arterioles as a tool to assess vascular changes

Hypertension

Volumn 54, Issue 2, 2009, Pages 384-387

  Ritt, Martin ^a   Schmieder, Roland E ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMINURIA; ARTERIOLE; BLOOD PRESSURE REGULATION; CEREBROVASCULAR DISEASE; CLINICAL ASSESSMENT TOOL; DOPPLER FLOWMETRY; HUMAN; HYPERTENSION; PRIORITY JOURNAL; RELIABILITY; RETINA BLOOD VESSEL; REVIEW; SCANNING LASER DOPPLER FLOWMETRY WITH AUTOMATIC FULL FIELD PERFUSION IMAGING ANALYSIS; WALL TO LUMEN RATIO; BLOOD FLOW; FEMALE; HOSPITALIZATION; LASER DOPPLER FLOWMETRY; MALE; MICROCIRCULATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PREDICTION AND FORECASTING; PROGNOSIS; RETINA ARTERY; RETINA DISEASE; RISK FACTOR; VASCULAR PATENCY; VASCULAR RESISTANCE;

ARTERIOLES; CEREBROVASCULAR DISORDERS; FEMALE; HUMANS; HYPERTENSION; LASER-DOPPLER FLOWMETRY; MALE; MICROCIRCULATION; PREDICTIVE VALUE OF TESTS; PROGNOSIS; REGIONAL BLOOD FLOW; RETINAL ARTERY; RETINAL DISEASES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; VASCULAR PATENCY; VASCULAR RESISTANCE;

EID: 68549104292     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.109.133025     Document Type: Review

References (21)

1. Wong TY, Mitchell P. Hypertensive retinopathy. N Engl J Med. 2004;351:2310-2317.
2. Ritt M, Harazny JM, Ott C, Schlaich MP, Schneider MP, Michelson G, Schmieder RE. Analysis of retinal arteriolar structure in never-treated patients with essential hypertension. J Hypertens. 2008;26:1427-1434.
3. Rizzoni D, De Ciuceis C, Porteri E, Paiardi S, Boari GEM, Mortini P, Cornali C, Cenzato M, Rodella LF, Borsani E, Rizzardi N, Platto C, Rezzani R, Agabiti Rosei E. Altered structure of small cerebral arteries in patients with essential hypertension. J Hypertens. 2009;27:838-845.
4. Heagerty AM, Aalkjaer C, Bund SJ, Korsgaard N, Mulvany MJ. Small artery structure in hypertension: dual processes of remodeling and growth. Hypertension. 1993;21:391-397.
5. Keith NM, Wagener HP, Barker NW. Some different types of essential hypertension: their course and prognosis. Am J Med Sci. 1939;197: 332-343.
6. Witt N, Wong TY, Hughes AD, Chaturvedi N, Klein BE, Evans R, McNamara M, Thom SA, Klein R. Abnormalities of retinal microvascular structure and risk of mortality from ischemic heart disease and stroke. Hypertension. 2006;47:975-981.
7. Wong TY, Klein R, Nieto FJ, Klein BE, Sharrett AR, Meuer SM, Hubbard LD, Tielsch JM. Retinal microvascular abnormalities and 10-year cardiovascular mortality: a population-based case-control study. Ophthalmology. 2003;110:933-940.
8. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, Grassi G, Heagerty AM, Kjeldsen SE, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, Schmieder RE, Boudier HA, Zanchetti A, Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemans I, Kristensen SD, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Erdine S, Kiowski W, Agabiti-Rosei E, Ambrosioni E, Lindholm LH, Viigimaa M, Adamopoulos S, Bertomeu V, Clement D, Farsang C, Gaita D, Lip G, Mallion JM, Manolis AJ, Nilsson PM, O'Brien E, Ponikowski P, Redon J, Ruschitzka F, Tamargo J, van Zwieten P, Waeber B, Williams B. 2007 guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens. 2007;25:1105-1187.
9. van den Born BJ, Hulsman CA, Hoekstra JB, Schlingemann RO, van Montfrans GA. Value of routine funduscopy in patients with hypertension: systematic review. BMJ. 2005;331:73.
10. Harazny JM, Ritt M, Baleanu D, Ott C, Heckmann J, Schlaich MP, Michelson G, Schmieder RE. Increased wall: lumen ratio of retinal arterioles in male patients with a history of a cerebrovascular event. Hypertension. 2007;50:623-629.
11. Park JB, Schiffrin EL. Small artery remodeling is the most prevalent (earliest?) form of target organ damage in mild essential hypertension. J Hypertens. 2001;19:921-930.
12. Rizzoni D, Porteri E, Boari GE, De Ciuceis C, Sleiman I, Muiesan ML, Castellano M, Miclini M, Agabiti-Rosei E. Prognostic significance of small-artery structure in hypertension. Circulation. 2003;108:2230-2235.
13. Mathiassen ON, Buus NH, Sihm I, Thybo NK, Morn B, Schroeder AP, Thygesen K, Aalkjaer C, Lederballe O, Mulvany MJ, Christensen KL. Small artery structure is an independent predictor of cardiovascular events in essential hypertension. J Hypertens. 2007;25:1021-1026.
14. De Ciuceis C, Porteri E, Rizzoni D, Rizzardi N, Paiardi S, Boari GE, Miclini M, Zani F, Muiesan ML, Donato F, Salvetti M, Castellano M, Tiberio GA, Giulini SM, Agabiti Rosei E. Structural alterations of subcutaneous small-resistance arteries may predict major cardiovascular events in patients with hypertension. Am J Hypertens. 2007;20:846-852.
15. Intengan HD, Schiffrin EL. Vascular remodeling in hypertension: roles of apoptosis, inflammation, and fibrosis. Hypertension. 2001;38:581-587.
16. Schiffrin EL. Remodeling of resistance arteries in essential hypertension and effects of antihypertensive treatment. Am J Hypertens. 2004;17: 1192-1200.
17. Izzard AS, Rizzoni D, Agabiti-Rosei E, Heagerty AM. Small artery structure and hypertension: adaptive changes and target organ damage. J Hypertens. 2005;23:247-250.
18. Lin WL, Essner E. Ultrastructural and permeability characteristics of retinal vessels in stroke-prone spontaneously hypertensive rats. Graefes Arch Clin Exp Ophthalmol. 1988;226:559-566.
19. Arribas SM, Gonzalez C, Graham D, Dominiczak AF, McGrath JC. Cellular changes induced by chronic nitric oxide inhibition in intact rat basilar arteries revealed by confocal microscopy. J Hypertens. 1997;15: 1685-1693.
20. Hubbard LD, Brothers RJ, King WN, Clegg LX, Klein R, Cooper LS, Sharrett AR, Davis MD, Cai J. Methods for evaluation of retinal microvascular abnormalities associated with hypertension/sclerosis in the Atherosclerosis Risk in Communities Study. Ophthalmology. 1999;106: 2269-2280.
21. Baleanu D, Ritt M, Harazny J, Heckmann J, Schmieder RE, Michelson G. Wall to lumen ratio of retinal arterioles and arteriole to venule ratio of retinal vessels in patients with cerebrovascular damage. Invest Ophthalmol Vis Sci. In press.