HIV type-1 transmission dynamics in recent seroconverters: Relationship with transmission of drug resistance and viral diversity

Antiviral Therapy

Volumn 14, Issue 4, 2009, Pages 551-556

  Recordon Pinson, Patricia ^a,b   Anies, Guerric ^a,b   Bruyand, Mathias ^c   Neau, Didier ^a,c   Morlat, Philippe ^a   Pellegrin, Jean Luc ^a   Groppi, Alexis ^b   Thiébaut, Rodolphe ^c   Dabis, François ^c   Fleury, Hervé ^a,b   Masquelier, Bernard ^a,b  

^a BORDEAUX UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ATAZANAVIR PLUS RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; REVERSE TRANSCRIPTASE, HUMAN IMMUNODEFICIENCY VIRUS 1; RNA DIRECTED DNA POLYMERASE; VIRUS RNA;

ADULT; AMINO ACID SEQUENCE; ANTIVIRAL RESISTANCE; ARTICLE; BOOTSTRAPPING; CD4 LYMPHOCYTE COUNT; FEMALE; GENE CLUSTER; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MAJOR CLINICAL STUDY; MALE; PHYLOGENY; PREVALENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEROCONVERSION; SPECIES DIVERSITY; VIRUS TRANSMISSION; BLOOD; DISEASE TRANSMISSION; DRUG EFFECT; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE;

ADULT; BASE SEQUENCE; DRUG RESISTANCE, VIRAL; FEMALE; HIV INFECTIONS; HIV REVERSE TRANSCRIPTASE; HIV SEROPOSITIVITY; HIV-1; HUMANS; MALE; MULTIGENE FAMILY; PHYLOGENY; RNA, VIRAL;

EID: 68549090707     PISSN: 13596535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Hirsch MS, Gunthard HF, Schapiro JM, et al. Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA panel. Clin Infect Dis 2008; 47:266-285.
2. Chaix ML, Descamps D, Harzic M, et al. Stable preyalence of genotypic drug resistance mutations but increase in non-B virus among patients with primary HIV-1 infection in France. AIDS 2003; 17:2635-2643.
3. Descamps D, Chaix NIL, Andre P, et al. French national sentinel survey of antiretroviral drug resistance in patients with HIV-1 primary infection and in antiretroviral-naive chronically infected patients in 2001-2002. J Acquir Immune Defic Syndr 2005; 38:545-552.
4. Masquelier B, Bhaskaran K, Pillay D, et al. Prevalence of transmitted HIV-1 drug resistance and the role of resistance algorithms: data from seroconverters in the CASCADE collaboration from 1987 to 2003. J Acquir Immune Defic Syndr 2005; 40:505-511.
5. Weinstock HS, Zaidi I, Heneine W, et al. The epidemiology. of antiretroviral drug resistance among drug-naive HIV-1-infected persons in 10 US cities. J Infect Dis 2004; 189:2174-2180.
6. Wensing AM, van de Vijver DA, Angarano G, et al. Prevalence of drug-resistant HIV-1 variants in untreated individuals in Europe: implications for clinical management. J Infect Dis 2005; 192:958-966.
7. Bannister WP, Cozzi-Lepri A, Clotet B, et al. Transmitted drug resistant HIV-1 and association with virologic and CD4 cell count response to combination antiretroviral therapy in the -EuroSIDA Study. J Acquir Immune Defic Syndr 2008; 48:324-333.
8. Brenner BG, Roger M, Routy JP, et al. High rates of forward transmission events after acute/early HIV-1 infection. J Infect Dis 2001; 195:951-959.
9. Lazaro E, Coureau G, Guedj J, et al. Change in T-lymphocyte count after initiation of highly active antiretroviral therapy in HIV-infected patients with history of Mycobacterium avium complex infection. Antivir Ther 2006; 11:343-350.
10. HIV French Resistance. HIV-1 genotypic drug resistance interpretation's algorithms. (Updated July 2008. Accessed 10 June 2009.) Available from http://www.hivfrenchresistance.org
11. Shafer RW, Rhee SY, Pillay D, et al. HIV-1 protease and reverse transcriptase mutations for drug resistance surveillance. AIDS 2007; 21:215-223.
12. Guindon S, Gascuel O. A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. Syst Biol 2003; 52:696-704.
13. Dereeper A, Guignon V, Blanc G, et al. Phylogeny.fr: robust phylogenetic analysis for the non-specialist. Nucleic Acids Res 2008; 36:W465-W469.
14. Yerly S, Junier T, Boffi E, et al. Drug resistance in newly HIV diagnosed individuals: transmission rate, clusters and persistence. Antivir Ther 2008; 13:A167.
15. Chaix ML, Galimand J, Descamps D, et al. Are patients with acute HIV-1 infection the mayor source of HIV transmission in France? A 5-year survey in the ANRS PRIMO Network. Antivir Ther 2008; 13:A150.
16. Kaye M, Chibo D, Birch C. Phylogenetic investigation of transmission pathways of drug-resistant HIV-1 utilizing pol sequences derived from resistance genotyping. J Acquir Immune Defic Syndr 2008; 49:9-16.
17. Brenner BG, Roger M, Moisi DD, et al. Transmission networks of drug resistance acquired in primary/early stage HIV infection. AIDS 2008; 22:2509-2515.