Pharmacokinetics of three alkaloids in Huanglianjiedu dcoction in rat serum by LC-MS-MS

Zhongguo Zhongyao Zazhi

Volumn 34, Issue 10, 2009, Pages 1276-1280

  Wu, Xiaoxia ^a   Peng, Juan ^a   Fan, Bin ^a   Yu, Youhua ^a  

^a INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

Berberine; Huanglianjiedu decoction; Jatrorrhizine; LC MS MS; Palmatine; Pharmacokinetics

Indexed keywords

BERBERINE; COPTIS CHINENSIS EXTRACT; JATRORRHIZINE; PALMATINE; TETRAHYDROPALMATINE;

ANIMAL EXPERIMENT; ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; ELECTROSPRAY; EXPERIMENTAL MODEL; FRAGMENTATION REACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION TRANSPORT; NONHUMAN; RAT; SERUM; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; VALIDATION STUDY;

ALKALOIDS; ANIMALS; BERBERINE; BERBERINE ALKALOIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; MALE; QUALITY CONTROL; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE STANDARDS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 68449103876     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Lu T, Liang Y, Song J, et al. Simultaneous determination of berberine and palmatine in rat plasma by HPLC-ESI-MS after oral administration of traditional Chinese medicinal preparation Huang-Lian-Jie-Du decoction and the pharmacokinetic application of the method[J]. J Pharm Biomed Anal, 2006,40:1218. (Pubitemid 43247461)