Occupational styrene exposure and neurobehavioural functions: A cohort study with repeated measurements

International Archives of Occupational and Environmental Health

Volumn 82, Issue 8, 2009, Pages 969-984

  Triebig, Gerhard ^a   Bruckner, Thomas ^b   Seeber, Andreas ^c  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

Author keywords

Chronic exposure; Cognitive tests; Current exposure; Neurobehavioural functions; Psychomotor tests; Styrene

Indexed keywords

CREATININE; MANDELIC ACID; PHENYLGLYOXYLIC ACID; STYRENE;

ADULT; AGE; ALCOHOL CONSUMPTION; ARTICLE; COGNITIVE DEFECT; COHORT ANALYSIS; CONTROLLED STUDY; EDUCATION; HUMAN; INDUSTRIAL WORKER; LANGUAGE; LONG TERM EXPOSURE; MAJOR CLINICAL STUDY; MENTAL PERFORMANCE; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; PSYCHOMOTOR DISORDER; RESPONSE TIME; RISK FACTOR;

ADULT; COHORT STUDIES; CROSS-SECTIONAL STUDIES; DISCRIMINATION (PSYCHOLOGY); FORM PERCEPTION; HUMANS; MALE; NEUROPSYCHOLOGICAL TESTS; NEUROTOXICITY SYNDROMES; OCCUPATIONAL DISEASES; OCCUPATIONAL EXPOSURE; PSYCHOMOTOR PERFORMANCE; QUESTIONNAIRES; STYRENE;

EID: 68449103254     PISSN: 03400131     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00420-008-0382-5     Document Type: Article

References (52)

1. Anger WK (1990) Worksite behavioral research: Results, sensitive methods, test batteries, and the transition from laboratory data to human health. Neurotoxicology 11:629-720
2. Anger WK (2003) Neurobehavioural tests and systems to assess neurotoxic exposures in the workplace and community. Occup Environ Med 60:531-538, 474
3. Benignus VA, Geller AM, Boyes WK, Bushnell PJ (2005) Human neurobehavioral effects of long-term exposure to styrene: A meta-analysis. Environ Health Perspect 113(5):532-538
4. Benton AL (1990) Der Benton-test. Handbuch. Huber, Bern, Stuttgart, Toronto
5. Cherry N, Rogers B, Venables H, Waldron HA, Wells G (1981) Acute behavioural effects of styrene exposure: A further analysis. Br J Ind Med 38:346-350
6. Cherry N, Gautrin D (1990) Neurotoxic effects of styrene: Further evidence. Br J Ind Med 47:29-37
7. Dalton P (2002) Odor, irritation and perception of health risk. Int Arch Occup Environ Health 75:283-290. doi: 10.1007/s00420-002-0312-x
8. De Rosa E, Cellini M, Sessa G, Scapellato ML, Marcuzzo G, Bartolucci GB (1996) The importance of sampling time and coexposure to acetone and biological monitoring of styrene-exposed workers. Appl Occup Environ Hyg 11:471-475
9. DFG Deutsche Forschungsgemeinschaft (1985) Analyses of hazardous substances in biological in biological materials. Methods for biological monitoring. In: Angerer J, Schaller KH (eds) Aromatic carboxylic acids, vol 2. Wiley, Weinheim, pp 47-66
10. DFG Deutsche Forschungsgemeinschaft (2006) List of MAK and BAT values. Commission for the investigation of health hazards in the work area: report no. 42. Wiley, Weinheim
11. DFG Deutsche Forschungsgemeinschaft (2007) Analytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe. Luftanalysen (Styrol). Wiley, Weinheim
12. Edling C, Anundi H, Johanson G, Nilsson K (1993) Increase in neuropsychiatric symptoms after occupational exposure to low levels of styrene. Br J Ind Med 50:843-850
13. Fallas C, Fallas J, Maslard P, Dally S (1992) Subclinical impairment of colour vision among workers exposed to styrene. Br J Ind Med 49:679-682
14. Flodin U, Ekbert K, Andersson L (1989) Neuropsychiatric effects of low exposure to styrene. Br J Ind Med 46:805-808
15. Gamberale F, Lisper HO, Olson BA (1976) The effect of styrene vapour on the reaction time of workers in the plastic boat industry. In: Horvath M (ed) adverse effects of environmental chemicals and psychotropic drugs. Elsevier, Amsterdam, pp 135-148
16. Golka K, Wiese A (2004) Carbohydrate-deficient transferrin (CDT)--a biomarker for long-term alcohol consumption. J Toxicol Environ Health 7:319-337. doi: 10.1080/10937400490432400
17. Guillemin MP, Berode M (1988) Biological monitoring of styrene: A review. Am Ind Hyg Assoc 49:497-505
18. Hall TA, Rebert CS (1994) Review of neurotoxicity of styrene in humans (Letter to the editor). Vet Hum Toxicol 36:249
19. Härkönen H, Lindstrom H, Seppalainen AM (1978) Exposure response relationship between styrene exposure and central nervous function. Scand J Work Environ Health 4:53-59
20. Hogstedt C, Andersson K, Hane M (1984) A questionnaire approach to the monitoring of early disturbances in central nervous functions. In: Aito A, Riihimäki V, Vainio H (eds) Biological monitoring and surveillance of workers exposed to chemicals. Hemisphere Publ Corp, Washington, pp 275-287
21. Hooisma J (1992) Provisional EURONEST battery version 1.0-manual. Concert action EURONEST of the EC, TNO Medical Biological Laboratory, Rijswik
22. HSE Health & Safety Executive (2007). European union risk assessment report styrene - draft for submission to SCHER, November 2007, UK
23. Ihrig A, Triebig G, Dietz MC (2001) Evaluation of a modified German version of the Q 16 questionnaire for neurotoxic symptoms in workers exposed to solvents. Occup Environ Med 58:19-23. doi: 10.1136/oem.58.1.19
24. Ikeda M, Koizumi A, Miyasaka M, Watanabe T (1982) Styrene exposure and biologic monitoring in FRP boat production. Int Arc Occu Environ Health 49:325-339
25. Jégaden D, Amann D, Simon JF, Habault M, Legoux B, Galopin P (1993) Study of the neurobehavioural toxicity of styrene at low levels of exposure. Int Arch Occup Environ Health 64:527-531. doi: 10.1007/ BF00381103
26. Jensen B, Mürer JL, Olsen E, Christensen JM (1994) Assessment of long-term styrene exposure: A comparative study of a logbook method and biological monitoring. Int Arch Occup Environ Health 66:399-405. doi: 10.1007/BF00383147
27. Kraus PH, Przuntek H, Kegelmann A, Klotz P (2000) Motor performance: normative data, age dependence and handedness. J Neural Transm 107:73-85. doi: 10.1007/s007020050006
28. Lehrl S, Triebig G, Fischer B (1995) Multiple choice vocabulary test MWT as a valid and short test to estimate premorbid intelligence. Acta Neurol Scand 91:335-345
29. Letz R (2003) Continuing challenges for computer-based neuropsychological tests. Neurotoxicology 24:479-489. doi: 10.1016/ S0161-813X(03)00047-0
30. Letz R, Pieper WA, Morris RD (1996) NES test performance in a large US army veteran sample: Relationships with both demographic factors and traditional neuropsychological measures. Neurotoxicol Teratol 18:381-390. doi: 10.1016/0892-0362(96)00023-2
31. Lezak MD (1995) Neuropsychological assessment, 3rd edn edn. HDI Publishers, Oxford
32. Lindström K, Härkonen H, Hernberg S (1976) Disturbances in psychological function in workers exposed to styrene. Scand J Work Environ Health 3:129-139
33. Mergler D, Campagna D, Belanger S, Larribe E, Huel G, Truchon G, Ostiguy C, Drolet D (1992) Neurotoxic effects among styrene-exposed workers II neurophysiological and behavioural changes. Travail Sante 8:16-21
34. Mergler D, Huel G, Belanger S, Bowler R, Truchon G, Drolet D, Ostiguy C (1996) Surveillance of early neurotoxic dysfunction. Neurotoxicology 17(3-4):803-812
35. Mizunuma K, Yasugi T, Kawai T, Horiguchi S, Ikeda M (1993) Exposure-excretion of styrene and acetone in factory workers: A comparison of a lipophilic solvent and a hydrophilic solvent. Arch Environ Contam Toxicol 25:129-133. doi: 10.1007/BF00230723
36. Mutti A, Mazzucchi A, Rusticelli P, Frigeri G, Artini G, Franchini I (1984) Exposure-effect and exposure-response relationships between occupational exposure to styrene and neuropsychological functions. Am J Ind Med 5:275-286. doi: 10.1002/ajim.4700050404
37. Ong CN, Shi CY, Chia SE, Chua SC, Ong HY, Lee BL, Ng TP, Teramoto K (1994) Biological monitoring of exposure to low concentrations of styrene. Am J Ind Med 25:719-730. doi: 10.1002/ajim.4700250511
38. Pahwa R, Kalra J (1993) A critical review of the neurotoxicity of styrene in humans. Vet Hum Toxicol 35:516-520
39. Rebert CS, Hall TA (1994) The neuroepidemiology of styrene: A critical review of representative literature. Crit Rev Toxicol 24:57-106. doi: 10.3109/10408449409020142
40. Schuhfried G (2001) Wiener Reaktionsgerät - Grundprogramm. Dr. G. Schuhfried GmbH, Mödling
41. Seeber A, Blaszkewicz M, Golka K, Hallier E, Kiesswetter E, Schäper M, van Thriel C (2004) Neurobehavioral effects of experimental exposures to low levels of styrene. Toxicol Lett 151:183-192. doi: 10.1016/ j.toxlet.2003.12.072
42. Seeber A, Bruckner T, Triebig G (in press) Occupational styrene exposure, colour vision and contrast sensitivity: A cohort study with repeated measurements. Int Arch Occup Environ Health
43. Seitz G, Stickel F, Fiehn W, Werle E, Simanowski UA, Seitz HK (1995) Kohlenhydrat-defizientes Transferrin. Ein neuer, hochspezifischer Marker für chronischen Alkoholkonsum. Dtsch Med Wochenschr Sect 120:391-395
44. Ska B, Vyskocil A, Tardif R, Carrier G, Thuot R, Muray K, Viau C (2003) Effects of peak concentrations on the neurotoxicity of styrene in volunteers. Hum Exp Toxicol 22:407-415
45. Smeets MA, Dalton P (2000) On the influence of personality on health symptom reporting to environmental exposure. Aroma-Chology Rev 8:1-10
46. Triebig G, Bruckner T, Seeber A (2008) Occupational styrene exposure and hearing loss: A cohort study with repeated measurements. Int Arch Occup Environ Health. doi: 10.1007/s00420-008-0355-8
47. Triebig G, Lehrl S, Dwelte D, Schaller KH, Valentin H (1989) Clinical and neurobehavioural study of the acute and chronic neurotoxicity of styrene. Br J Ind Med 46:799-804
48. Tsai SY, Chen JD (1996) Neurobehavioral effects of occupational exposure to low-level styrene. Neurotoxicol Teratol 18:463-469. doi: 10.1016/ 0892-0362(96)00035-9
49. Viaene MK, Veulemans H, Masschelein R (1998) Experience with a vocabulary test for workers previously and still exposed to styrene. Scand J Work Environ Health 24:308-311
50. Viaene MK, Pauwels W, Veulemans H, Roels HA, Masschelein R (2001) Neurobehavioural changes and persistence of complaints in workers exposed to styrene in a polyester boat building plant: Influence of exposure characteristics and microsomal epoxide hydrolase phenotype. Occup Environ Med 58:103-112. doi: 10.1136/oem.58.2.103
51. Watson D, Clark LA (1988) Development and validation of brief measures of positive and negative affect: The PANAS scales. J Pers Soc Psychol 54:1063-1070. doi: 10.1037/0022-3514.54.6.1063
52. Wolf K, Bienfait HG, Brohmann P, Brucksch E, Stanetzek I, Teuffel-Schilling C, Albracht G, Au M, Bolm-Audorff U (2000) Styrolbelastung von Beschäftigten in der Polyesterharz verarbeitenden Industrie. Arbeitsmed Sozialmed Umweltmed 35:312-315