Editorial: Salivary testing opens a Pandora's box of issues surrounding accurate measurement of testosterone in women

Menopause

Volumn 16, Issue 4, 2009, Pages 630-631

  Davison, Sonia ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTANOLONE; HYDROCORTISONE; SEX HORMONE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE;

COST EFFECTIVENESS ANALYSIS; CUSHING SYNDROME; DIAGNOSTIC ACCURACY; EDITORIAL; HORMONE DETERMINATION; HUMAN; IMMUNOASSAY; POSTMENOPAUSE; RADIOIMMUNOASSAY; RELIABILITY; SALIVA ANALYSIS; SALIVA LEVEL; TESTOSTERONE BLOOD LEVEL; TESTOSTERONE SALIVA LEVEL; ULTRAFILTRATION; AGING; BLOOD; CHEMISTRY; COMPARATIVE STUDY; FEMALE; MENSTRUAL CYCLE; METABOLISM; NOTE; SALIVA; SENSITIVITY AND SPECIFICITY;

AGING; FEMALE; HUMANS; MENSTRUAL CYCLE; POSTMENOPAUSE; SALIVA; SENSITIVITY AND SPECIFICITY; SEX HORMONE-BINDING GLOBULIN; TESTOSTERONE;

EID: 68449093180     PISSN: 10723714     EISSN: None     Source Type: Journal    
DOI: 10.1097/GME.0b013e3181a8f914     Document Type: Editorial

References (20)

1. Flyckt RL, Liu J, Frasure H, et al. Comparison of salivary versus serum testosterone levels in postmenopausal women receiving transdermal testosterone supplementation versus placebo. Menopause 2009;16:680-688.
2. Nieman LK, Biller BM, Findling JW, et al. The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2008;93:1526-1540.
3. Taieb J, Mathian B, Millot F, et al. Testosterone measured by 10 immunoassays and by isotope-dilution gas chromatography-mass spectrometry in sera from 116 men, women, and children. Clin Chem 2003;49:1381-1395.
4. Demers LM. Testosterone and estradiol assays: current and future trends. Steroids 2008;73:1333-1338.
5. Dunn JF, Nisula BC, Rodbard D. Transport of steroid hormones: binding of 21 endogenous steroids to both testosterone-binding globulin and corticosteroid-binding globulin in human plasma. J Clin Endocrinol Metab 1981;53:58-68.
6. Wheeler MJ. The determination of bio-available testosterone. Ann Clin Biochem 1995;32:345-357.
7. Davison SL, Bell R, Montalto JG, et al. Measurement of total testosterone in women: comparison of a direct radioimmunoassay versus radioimmunoassay after organic solvent extraction and celite column partition chromatography. Fertil Steril 2005;84:1698-1704.
8. Hsing AW, Stanczyk FZ, Belanger A, et al. Reproducibility of serum sex steroid assays in men by RIA and mass spectrometry. Cancer Epidemiol Biomarkers Prev 2007;16:1004-1008.
9. Slaats EH, Kennedy JC, Kruijswijk H. Interference of sex-hormone binding globulin in the "Coat-A-Count" testosterone no-extraction radioimmunoassay. Clin Chem 1987;33:300-302.
10. Masters AM, Hahnel R. Investigation of sex-hormone binding globulin interference in direct radioimmunoassays for testosterone and estradiol. Clin Chem 1989;35:979-984.
11. Miller KK, Rosner W, Lee H, et al. Measurement of free testosterone in normal women and women with androgen deficiency: comparison of methods. J Clin Endocrinol Metab 2004;89:525-533.
12. Rahhal SN, Fuqua JS, Lee PA. The impact of assay sensitivity in the assessment of diseases and disorders in children. Steroids 2008;73:1322-1327.
13. Sodergard R, Backstrom T, Shanbhag V, Carstensen H. Calculation of free and bound fractions of testosterone and estradiol-17 beta to human plasma proteins at body temperature. J Steroid Biochem 1982;16:801-810.
14. Davison SL, Bell R, Donath S, Montalto JG, Davis SR. Androgen levels in adult females: changes with age, menopause, and oophorectomy. J Clin Endocrinol Metab 2005;90:3847-3853.
15. Judd HL, Lucas WE, Yen SS. Effect of oophorectomy on circulating testosterone and androstenedione levels in patients with endometrial cancer. Am J Obstet Gynecol 1974;118:793-798.
16. Gaspard UJ, Dubois M, Gillain D, Franchimont P, Duvivier J. Ovarian function is effectively inhibited by a low-dose triphasic oral contraceptive containing ethinylestradiol and levonorgestrel. Contraception 1984;29:305-318.
17. Tazuke S, Khaw KT, Barrett-Connor E. Exogenous estrogen and endogenous sex hormones. Medicine 1992;71:44-51.
18. Panico S, Pisani P, Muti P, et al. Diurnal variation of testosterone and estradiol: a source of bias in comparative studies on breast cancer. J Endocrinol Invest 1990;13:423-426.
19. Vermeulen A, Verdonck L. Plasma androgen levels during the menstrual cycle. Am J Obstet Gynecol 1976;125:491-494.
20. Sinha-Hikim I, Arver S, Beall G, et al. The use of a sensitive equilibrium dialysis method for the measurement of free testosterone levels in healthy, cycling women and in human immunodeficiency virus-infected women. J Clin Endocrinol Metab 1998;83:1312-1318.