메뉴 건너뛰기




Volumn 175, Issue 2, 2009, Pages 661-667

The complement inhibitor FUT-175 suppresses T cell autoreactivity in experimental autoimmune encephalomyelitis

Author keywords

[No Author keywords available]

Indexed keywords

CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; GAMMA INTERFERON; INTERLEUKIN 17; MYELIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; NAFAMSTAT MESILATE;

EID: 68449086571     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2009.081093     Document Type: Article
Times cited : (23)

References (34)
  • 1
    • 17644396349 scopus 로고    scopus 로고
    • Immunology of multiple sclerosis
    • Sospedra M, Martin R: Immunology of multiple sclerosis. Annu Rev Immunol 2005, 23:683-747
    • (2005) Annu Rev Immunol , vol.23 , pp. 683-747
    • Sospedra, M.1    Martin, R.2
  • 2
    • 43049101640 scopus 로고    scopus 로고
    • The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice
    • Guo B, Chang EY, Cheng G: The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J Clin Invest 2008, 118:1680-1690
    • (2008) J Clin Invest , vol.118 , pp. 1680-1690
    • Guo, B.1    Chang, E.Y.2    Cheng, G.3
  • 3
    • 33644846142 scopus 로고    scopus 로고
    • The use of glatiramer acetate in the treatment of multiple sclerosis
    • Wolinsky JS: The use of glatiramer acetate in the treatment of multiple sclerosis. Adv Neurol 2006, 98:273-292
    • (2006) Adv Neurol , vol.98 , pp. 273-292
    • Wolinsky, J.S.1
  • 4
    • 28244485979 scopus 로고    scopus 로고
    • Mitoxantrone in the treatment of multiple sclerosis
    • Morrissey SP, Le Page E, Edan G: Mitoxantrone in the treatment of multiple sclerosis. Int MSJ 2005, 12:74-87
    • (2005) Int MSJ , vol.12 , pp. 74-87
    • Morrissey, S.P.1    Le Page, E.2    Edan, G.3
  • 5
    • 33644850643 scopus 로고    scopus 로고
    • Lessons for clinical trials from natalizumab in multiple sclerosis
    • Chaudhuri A: Lessons for clinical trials from natalizumab in multiple sclerosis. BMJ 2006, 332:416-419
    • (2006) BMJ , vol.332 , pp. 416-419
    • Chaudhuri, A.1
  • 6
    • 33644842110 scopus 로고    scopus 로고
    • Animal models for multiple sclerosis
    • Owens T: Animal models for multiple sclerosis. Adv Neurol 2006, 98:77-89
    • (2006) Adv Neurol , vol.98 , pp. 77-89
    • Owens, T.1
  • 9
    • 46949104323 scopus 로고    scopus 로고
    • IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition
    • Kroenke MA, Carlson TJ, Andjelkovic AV, Segal BM: IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. J Exp Med 2008, 205:1535-1541
    • (2008) J Exp Med , vol.205 , pp. 1535-1541
    • Kroenke, M.A.1    Carlson, T.J.2    Andjelkovic, A.V.3    Segal, B.M.4
  • 11
    • 33644745156 scopus 로고    scopus 로고
    • Macrophages from C3-deficient mice have impaired potency to stimulate alloreactive T cells
    • Zhou W, Patel H, Li K, Peng Q, Villiers MB, Sacks SH: Macrophages from C3-deficient mice have impaired potency to stimulate alloreactive T cells. Blood 2006, 107:2461-2469
    • (2006) Blood , vol.107 , pp. 2461-2469
    • Zhou, W.1    Patel, H.2    Li, K.3    Peng, Q.4    Villiers, M.B.5    Sacks, S.H.6
  • 12
    • 41349100253 scopus 로고    scopus 로고
    • Local production and activation of complement up-regulates the allostimulatory function of dendritic cells through C3a-C3aR interaction
    • Peng Q, Li K, Anderson K, Farrar CA, Lu B, Smith RA, Sacks SH, Zhou W: Local production and activation of complement up-regulates the allostimulatory function of dendritic cells through C3a-C3aR interaction. Blood 2008, 111:2452-2461
    • (2008) Blood , vol.111 , pp. 2452-2461
    • Peng, Q.1    Li, K.2    Anderson, K.3    Farrar, C.A.4    Lu, B.5    Smith, R.A.6    Sacks, S.H.7    Zhou, W.8
  • 14
    • 38449105692 scopus 로고    scopus 로고
    • Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production
    • Lalli PN, Strainic MG, Lin F, Medof ME, Heeger PS: Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production. J Immunol 2007, 179:5793-5802
    • (2007) J Immunol , vol.179 , pp. 5793-5802
    • Lalli, P.N.1    Strainic, M.G.2    Lin, F.3    Medof, M.E.4    Heeger, P.S.5
  • 15
    • 52649176344 scopus 로고    scopus 로고
    • Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis
    • Lalli PN, Strainic MG, Yang M, Lin F, Medof ME, Heeger PS: Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis. Blood 2008, 112:1759-1766
    • (2008) Blood , vol.112 , pp. 1759-1766
    • Lalli, P.N.1    Strainic, M.G.2    Yang, M.3    Lin, F.4    Medof, M.E.5    Heeger, P.S.6
  • 17
    • 0021713655 scopus 로고
    • Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes
    • Medof ME, Kinoshita T, Nussenzweig V: Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes. J Exp Med 1984, 160:1558-1578
    • (1984) J Exp Med , vol.160 , pp. 1558-1578
    • Medof, M.E.1    Kinoshita, T.2    Nussenzweig, V.3
  • 18
    • 0019817468 scopus 로고
    • New synthetic inhibitors of C1r. C1 esterase, thrombin, plasmin, kallikrein, and trypsin
    • Fujii S, Hitomi Y: New synthetic inhibitors of C1r. C1 esterase, thrombin, plasmin, kallikrein, and trypsin. Biochim Biophys Acta 1981, 661:342-345
    • (1981) Biochim Biophys Acta , vol.661 , pp. 342-345
    • Fujii, S.1    Hitomi, Y.2
  • 19
    • 0034828653 scopus 로고    scopus 로고
    • Successful treatment of severe acute pancreatitis by the combination therapy of continuous arterial infusion of a protease inhibitor and continuous hemofiltration
    • Nakase H, Itani T, Mimura J, Kawasaki T, Komori H, Okazaki K, Chiba T: Successful treatment of severe acute pancreatitis by the combination therapy of continuous arterial infusion of a protease inhibitor and continuous hemofiltration. J Gastroenterol Hepatol 2001, 16:944-945
    • (2001) J Gastroenterol Hepatol , vol.16 , pp. 944-945
    • Nakase, H.1    Itani, T.2    Mimura, J.3    Kawasaki, T.4    Komori, H.5    Okazaki, K.6    Chiba, T.7
  • 20
    • 0029915798 scopus 로고    scopus 로고
    • Continuous regional arterial infusion of protease inhibitor and antibiotics in acute necrotizing pancreatitis
    • Takeda K, Matsuno S, Sunamura M, Kakugawa Y: Continuous regional arterial infusion of protease inhibitor and antibiotics in acute necrotizing pancreatitis. Am J Surg 1996, 171:394-398
    • (1996) Am J Surg , vol.171 , pp. 394-398
    • Takeda, K.1    Matsuno, S.2    Sunamura, M.3    Kakugawa, Y.4
  • 23
    • 0030953579 scopus 로고    scopus 로고
    • Application of a new anticoagulant (Nafamostat Mesilate) to control hemorrhagic complications during extracorporeal membrane oxygenation-a preliminary report
    • Nagaya M, Futamura M, Kato J, Niimi N, Fukuta S: Application of a new anticoagulant (Nafamostat Mesilate) to control hemorrhagic complications during extracorporeal membrane oxygenation-a preliminary report. J Pediatr Surg 1997, 32:531-535
    • (1997) J Pediatr Surg , vol.32 , pp. 531-535
    • Nagaya, M.1    Futamura, M.2    Kato, J.3    Niimi, N.4    Fukuta, S.5
  • 24
    • 0035450556 scopus 로고    scopus 로고
    • Bulk production and functional analyses of mouse CD55's native and deglycosylated active domains
    • Lin F, Immormino RM, Shoham M, Medof ME: Bulk production and functional analyses of mouse CD55's native and deglycosylated active domains. Arch Biochem Biophys 2001, 393:67-72
    • (2001) Arch Biochem Biophys , vol.393 , pp. 67-72
    • Lin, F.1    Immormino, R.M.2    Shoham, M.3    Medof, M.E.4
  • 25
    • 0024441484 scopus 로고
    • Immunohistochemical localisation of terminal complement component C9 in experimental allergic encephalomyelitis
    • Linington C, Lassmann H, Morgan BP, Compston DA: Immunohistochemical localisation of terminal complement component C9 in experimental allergic encephalomyelitis. Acta Neuropathol 1989, 79:78-85
    • (1989) Acta Neuropathol , vol.79 , pp. 78-85
    • Linington, C.1    Lassmann, H.2    Morgan, B.P.3    Compston, D.A.4
  • 26
    • 0036569324 scopus 로고    scopus 로고
    • Attenuation of experimental allergic encephalomyelitis in complement component 6-deficient rats is associated with reduced complement C9 deposition. P-selectin expression, and cellular infiltrate in spinal cords
    • Tran GT, Hodgkinson SJ, Carter N, Killingsworth M, Spicer ST, Hall BM: Attenuation of experimental allergic encephalomyelitis in complement component 6-deficient rats is associated with reduced complement C9 deposition. P-selectin expression, and cellular infiltrate in spinal cords. J Immunol 2002, 168:4293-4300
    • (2002) J Immunol , vol.168 , pp. 4293-4300
    • Tran, G.T.1    Hodgkinson, S.J.2    Carter, N.3    Killingsworth, M.4    Spicer, S.T.5    Hall, B.M.6
  • 27
    • 0018115115 scopus 로고
    • Experimental allergic encephalomyelitis in cobra venom factor-treated and C4-deficient guinea pigs
    • Morariu MA, Dalmasso AP: Experimental allergic encephalomyelitis in cobra venom factor-treated and C4-deficient guinea pigs. Ann Neurol 1978, 4:427-430
    • (1978) Ann Neurol , vol.4 , pp. 427-430
    • Morariu, M.A.1    Dalmasso, A.P.2
  • 28
    • 0028179910 scopus 로고
    • Soluble recombinant complement receptor 1 inhibits inflammation and demyelination in antibody-mediated demyelinating experimental allergic encephalomyelitis
    • Piddlesden SJ, Storch MK, Hibbs M, Freeman AM, Lassmann H, Morgan BP: Soluble recombinant complement receptor 1 inhibits inflammation and demyelination in antibody-mediated demyelinating experimental allergic encephalomyelitis. J Immunol 1994, 152:5477-5484
    • (1994) J Immunol , vol.152 , pp. 5477-5484
    • Piddlesden, S.J.1    Storch, M.K.2    Hibbs, M.3    Freeman, A.M.4    Lassmann, H.5    Morgan, B.P.6
  • 29
    • 0032736185 scopus 로고    scopus 로고
    • Central nervous system-targeted expression of the complement inhibitor sCrry prevents experimental allergic encephalomyelitis
    • Davoust N, Nataf S, Reiman R, Holers MV, Campbell IL, Barnum SR: Central nervous system-targeted expression of the complement inhibitor sCrry prevents experimental allergic encephalomyelitis. J Immunol 1999, 163:6551-6556
    • (1999) J Immunol , vol.163 , pp. 6551-6556
    • Davoust, N.1    Nataf, S.2    Reiman, R.3    Holers, M.V.4    Campbell, I.L.5    Barnum, S.R.6
  • 30
    • 0029795542 scopus 로고    scopus 로고
    • The C5a chemoattractant receptor mediates mucosal defense to infection
    • Hopken UE, Lu B, Gerard NP, Gerard C: The C5a chemoattractant receptor mediates mucosal defense to infection. Nature 1996, 383:86 -89
    • (1996) Nature , vol.383 , pp. 86-89
    • Hopken, U.E.1    Lu, B.2    Gerard, N.P.3    Gerard, C.4
  • 31
    • 34247263694 scopus 로고    scopus 로고
    • Complement in experimental autoimmune encephalomyelitis revisited: C3 is required for development of maximal disease
    • Szalai AJ, Hu X, Adams JE, Barnum SR: Complement in experimental autoimmune encephalomyelitis revisited: C3 is required for development of maximal disease. Mol Immunol 2007, 44:3132-3136
    • (2007) Mol Immunol , vol.44 , pp. 3132-3136
    • Szalai, A.J.1    Hu, X.2    Adams, J.E.3    Barnum, S.R.4
  • 32
    • 0035886199 scopus 로고    scopus 로고
    • The allogeneic T and B cell response is strongly dependent on complement components C3 and C4
    • Marsh JE, Farmer CK, Jurcevic S, Wang Y, Carroll MC, Sacks SH: The allogeneic T and B cell response is strongly dependent on complement components C3 and C4. Transplantation 2001, 72:1310-1318
    • (2001) Transplantation , vol.72 , pp. 1310-1318
    • Marsh, J.E.1    Farmer, C.K.2    Jurcevic, S.3    Wang, Y.4    Carroll, M.C.5    Sacks, S.H.6
  • 33
    • 0034997865 scopus 로고    scopus 로고
    • Targeting complement in therapy
    • Kirschfink M: Targeting complement in therapy. Immunol Rev 2001, 180:177-189
    • (2001) Immunol Rev , vol.180 , pp. 177-189
    • Kirschfink, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.