Comparative modulation by 3α,5α and 3β,5β neurosteroids of GABA binding sites during avian central nervous system development

Neurochemical Research

Volumn 23, Issue 2, 1998, Pages 155-161

  Viapiano, Mariano S ^a   Fiszer De Plazas, Sara ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Avian CNS; Chick optic lobe; Development; GABA(A) receptor; Neurosteroids

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 3BETA HYDROXY 5BETA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; NEUROSTEROID; TRITIUM;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN DEVELOPMENT; CENTRAL NERVOUS SYSTEM; CHICKEN; CONTROLLED STUDY; EMBRYO; GABAERGIC SYSTEM; NEUROMODULATION; NEWBORN; NONHUMAN; OPTIC LOBE; PRIORITY JOURNAL; STEROIDOGENESIS; SYNAPTIC MEMBRANE;

ANIMALS; BINDING SITES; CENTRAL NERVOUS SYSTEM; CHICK EMBRYO; GAMMA-AMINOBUTYRIC ACID; ISOMERISM; OPTIC LOBE; PREGNANOLONE; RECEPTORS, GABA; SYNAPTIC MEMBRANES;

ANIMALIA; AVES; GALLUS GALLUS; MAMMALIA; TRITIUM;

EID: 6844260522     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022472623472     Document Type: Article

References (37)

1. Olsen, R. W., Stauber, G. B., King, R. G., Yang, J., and Dilber, A. 1986. Structure and Function of the Barbiturate-modulated Benzodiazepine GABA receptor protein complex. Pages 21-31. in Biggio, G. and Costa E., (eds.), GABAergic Transmission and Anxiety. Raven Press, New York.
2. Olsen, R. W. 1981. GABA-Benzodiazepine-Barbiturate receptor interactions. J. Neurochem. 37:1-13.
3. Costa, E., and Guidotti. A. 1979. Molecular mechanisms in the receptor action of benzodiazepine. A. Rev. Pharmac. Toxicol. 19:531-545.
4. A binding by benzodiazepines and related anxiolytics. Eur. J. Pharmacol. 89:193-198.
5. Asano, T., and Ogasawara, N. 1981. Stimulation of GABA receptor binding by barbiturates. Eur. J. Pharmacol. 77:355-357.
6. Willow, M., and Johnston, G. A. 1981. Enhancement by anesthetic and convulsant barbiturates of GABA binding to rat brain synaptosomal membranes. J. Neurosci. 1:364-367.
7. A receptor complex. Brain. Res. 596:238-242.
8. Harris, B. D., Wong, G., Moody, E. J., and Skolnick, P. 1995. Different subunit requirements for volatile and nonvolatile anesthetics at gamma-aminobutyric acid type A receptors. Mol. Pharmacol. 47:363-367.
9. Majewska, M. D., Harrison, N. L, Schwartz, R. D. Barker, J. L., and Paul, S. M. 1986. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptors. Science 232:1004-1007.
10. Harrison, N. L., Majewska, M. D., Harrington, J. W., and Barker, J. L. 1987. Structure-activity relationships for steroid interaction with the γ-aminobutyric acid A receptor complex. J. Pharmacol. Exp. Ther. 241:346-353.
11. Purdy, R. H., Morrow, A. L., Moore, P. H., and Paul, S. M. 1991. Stress-induced elevations of γ-aminobutyric acid type A receptor-active steroids in the rat brain. Proc. Natl. Acad. Sci. USA 88: 4553-4557.
12. Bitran, D., Shiekh, M., and McLeod, M. 1995. Anxiolytic effect of progesterone is mediated by the neurosteroid allopregnanolone at brain GABAA receptors. J. Neuroendocrinol. 7:171-177.
13. A receptor by progesterone metabolites. Proc. R. Soc. London. B231:359-369.
14. A receptor by depressant barbiturates and pregnane steroids. Br. J. Pharmacol. 94:1257-1269.
15. Hill-Venning, C., Belelli, D., Peters, J. A., Lambert, J. J. 1994. Electrophysiological studies of neurosteroid modulation of gamma aminobutyric acid type A receptor. Methods in Neurosciences 22: 446-467.
16. Gee, K. W., Bolger, M. M., Brinton, R. E., Coirini, H., and McEwen, B. 1988. Steroid modulation of the chloride ionophore in rat brain: Structure-activity requirements, regional dependence and mechanism of action. J. Pharmacol. Exp. Ther. 246:803-812.
17. Wieland, S., Belluzi, J., Stein, L., and Lan, N. 1995. Comparative behavioral characterization of the neuroactive steroids 3α-OH,5α-pregnan-20-one and 3α-OH,5β-pregnan-20-one in rodents. Psychopharmacol. 118:65-71.
18. Carboni, E., Wieland, S., Lan, N. C., and Gee, K. 1996. Anxiolytic properties of endogenously occurring pregnanediols in two rodent models of anxiety. Psychopharmacol. 126:173-178.
19. 3H]-Flunitrazepam binding suggests more than one class of binding sites for steroids at GABAA receptors. Neuropharmacol. 32:59-63.
20. Fiszer de Plazas S., and Mitridate de Novara, A. 1990. Effect of diazepam on the low affinity GABA binding sites at different developmental stages of the chick optic lobe. Neurochem. Int. 17: 381-387.
21. Fiszer de Plazas, S., Viapiano, M. S., and Mitridate de Novara, A. M. 1995. Pentobarbital modulatory effect on GABA binding sites in developing chick optic lobe. Int. J. Devl. Neuroscience 13:783-789.
22. Fiszer de Plazas, S., Conterjnic, D., and Flores, V. 1991. Effect of a simple visual pattern on the early postnatal development of GABA receptor sites in the chick optic lobe. Int. J. Devl. Neuroscience 9:195-201.
23. Rios, H., Flores, V., and Fiszer de Plazas, S. 1987. Effect of light-and dark-rearing on the postnatal development of GABA receptor sites in the chick optic lobe. Int. J. Devl. Neuroscience 5:319-325.
24. Nakamura, T., and Tanabe, Y. 1975. In vitro metabolism of steroid hormones by chicken brain. Acta Endocr. Copenh. 75:410-416.
25. Lowry, D. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. 1955. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265-275.
26. Enna, S. J., and Snyder, S. H. 1975. Properties of γ-aminobutyric acid GABA receptor binding in rat brain synaptic membrane fractions. Brain. Res. 100:81-97.
27. Roodbard D., Munson, P. J., and Thakur, A. K. 1980. Quantitative characterization of hormone receptors. Cancer. 46:2907-2918.
28. Baulieu, E. E., and Robel, P. 1990. Neurosteroids: A new brain function?. J. Steroid Biochem. Molec. Biol. 37:395-403.
29. Kenakin T. P., Bond, R., and Bonner, T. I. 1992. Definition of Pharmacological Receptors. Pharm. Rev. 44:351-361.
30. Kenakin, T. P. 1993. Pharmacologie analysis of drug-receptor interaction. 2nd. Ed. Raven Press, New York, 1993.
31. Morrow, A. L., Pace, J. R., Purdy, R. H., and Paul, S. M. 1990. Characterization of steroid interactions with γ-aminobutyric acid-receptor gated chlorid ion channels: Evidence for multiple steroid recognition sites. Mol. Pharmacol. 37:263-270.
32. 3H]-muscimol binding to the GABAA receptor complex in rat cortex. Eur. J. Pharmacol. 288:157-162.
33. Laurie, D. J. Wisden, W., and Seeburg, P. H. 1992. The distribution of thirteen GABAA receptor subunits mRNAs in the rat brain. III. Embryonic and postnatal development. J. Neurosci, 12:4151-4172.
34. Aragonés, A., Gonzalez, C. B., Spinedi, N. C., and Lantos, C. P. 1991. Regulatory effects of 5-β reduced steroids. J. Steroid Biochem. Molec. Biol. 39:253-263.
35. Gonzalez, C. B., Cozza, E. N., Bedners, M. E. O., Lantos, C. P., and Aragones, A. 1983. Progesterone and its reductive metabolism in steroidogenic tissues of the developing hen embryo. Gen. Comp. Endocr. 51:384-393.
36. Pedemera, E., and Lantos, C. 1973. The biosynthesis of adrenal steroids by the 15-day-old chick embryo. Gen. Comp. Endocr. 20: 331-341.
37. Aragonés, A., Gonzalez, C. B., Lantos, C. P., and Sancovich, H. A. 1985. Progesterone, its A/B cis reduction and delta-aminolevulinic acid synthetase in the developing hen. Acta Physiol. Pharmacol. Latinoam. 35:379-397.