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Volumn 41, Issue 2, 1997, Pages 103-108

Pharmacokinetics of CPT-11 in rhesus monkeys

Author keywords

CPT 11; Monkey; Pharmacokinetics

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; IRINOTECAN;

EID: 6844254547     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050715     Document Type: Article
Times cited : (13)

References (21)
  • 4
    • 0030055094 scopus 로고    scopus 로고
    • Current perspectives on camptothecins in cancer treatment
    • Dancey J, Eisenhauer EA (1996) Current perspectives on camptothecins in cancer treatment. Br J Cancer 74: 327-338
    • (1996) Br J Cancer , vol.74 , pp. 327-338
    • Dancey, J.1    Eisenhauer, E.A.2
  • 5
    • 0028340588 scopus 로고
    • Application of pharmacokinetically guided dose escalation with respect to cell cycle phase specificity
    • Fuse E, Kobayashi S, Inaba M, Suzuki H, Sugiyama Y (1994) Application of pharmacokinetically guided dose escalation with respect to cell cycle phase specificity. J Natl Cancer Inst 86: 989-996
    • (1994) J Natl Cancer Inst , vol.86 , pp. 989-996
    • Fuse, E.1    Kobayashi, S.2    Inaba, M.3    Suzuki, H.4    Sugiyama, Y.5
  • 6
    • 0028212845 scopus 로고
    • Different modes of cell-killing action between DNA topoisomerase I and II inhibitors revealed by kinetic analysis
    • Inaba M, Mitsuhashi J, Kawada S, Nakano H (1994) Different modes of cell-killing action between DNA topoisomerase I and II inhibitors revealed by kinetic analysis. Jpn J Cancer Res 85: 187-193
    • (1994) Jpn J Cancer Res , vol.85 , pp. 187-193
    • Inaba, M.1    Mitsuhashi, J.2    Kawada, S.3    Nakano, H.4
  • 7
    • 0025342506 scopus 로고
    • Nonlinear pharmacokinetics of CPT-11 in rats
    • Kaneda N, Yokokura T (1990) Nonlinear pharmacokinetics of CPT-11 in rats. Cancer Res 50: 1721-1725
    • (1990) Cancer Res , vol.50 , pp. 1721-1725
    • Kaneda, N.1    Yokokura, T.2
  • 8
    • 0025272187 scopus 로고
    • Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse
    • Kaneda N, Nagata H, Furuta T, Yokokura T (1990) Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse. Cancer Res 50: 1715-1720
    • (1990) Cancer Res , vol.50 , pp. 1715-1720
    • Kaneda, N.1    Nagata, H.2    Furuta, T.3    Yokokura, T.4
  • 10
    • 0023910386 scopus 로고
    • Cell killing action of cell cycle phase-non-specific antitumor agents is dependent on concentration-time product
    • Ozawa S, Sugiyama Y, Mitsuhashi Y, Kobayashi T, Inaba M (1988) Cell killing action of cell cycle phase-non-specific antitumor agents is dependent on concentration-time product. Cancer Chemother Pharmacol 21: 185-190
    • (1988) Cancer Chemother Pharmacol , vol.21 , pp. 185-190
    • Ozawa, S.1    Sugiyama, Y.2    Mitsuhashi, Y.3    Kobayashi, T.4    Inaba, M.5
  • 11
    • 0024327711 scopus 로고
    • Kinetic analysis of cell killing effect induced by cytosine arabinoside and cisplatin in relation to cell cycle phase specificity in human colon cancer and Chinese hamster cells
    • Ozawa S, Sugiyama Y, Mitsuhashi J, Inaba M (1989) Kinetic analysis of cell killing effect induced by cytosine arabinoside and cisplatin in relation to cell cycle phase specificity in human colon cancer and Chinese hamster cells. Cancer Res 49: 3823-3828
    • (1989) Cancer Res , vol.49 , pp. 3823-3828
    • Ozawa, S.1    Sugiyama, Y.2    Mitsuhashi, J.3    Inaba, M.4
  • 12
    • 0028670840 scopus 로고
    • Kinetics of the in vivo interconversion of the carboxylate and lactone forms of irinotecan (CPT-11) and of its metabolite SN-38 in patients
    • Rivory LP, Chatelut E, Canal P, Mathieu-Boue A, Robert J (1994) Kinetics of the in vivo interconversion of the carboxylate and lactone forms of irinotecan (CPT-11) and of its metabolite SN-38 in patients. Cancer Res 54: 6330-6333
    • (1994) Cancer Res , vol.54 , pp. 6330-6333
    • Rivory, L.P.1    Chatelut, E.2    Canal, P.3    Mathieu-Boue, A.4    Robert, J.5
  • 13
    • 0030580064 scopus 로고    scopus 로고
    • Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN-38), by human liver carboxylesterase
    • Rivory LP, Bowles MR, Robert J, Pond SM (1996) Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN-38), by human liver carboxylesterase. Biochem Pharmacol 52: 1103-1111
    • (1996) Biochem Pharmacol , vol.52 , pp. 1103-1111
    • Rivory, L.P.1    Bowles, M.R.2    Robert, J.3    Pond, S.M.4
  • 15
    • 0028158012 scopus 로고
    • Phase 1 pharmacological study of the novel topoisomerase I inhibitor 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks
    • Rowinsky EK, Grochow LB, Ettinger DS, Sartorius SE, Lubejko BG, Chen T-L, Rock MK, Donehower RC (1994) Phase 1 pharmacological study of the novel topoisomerase I inhibitor 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks. Cancer Res 54: 427-436
    • (1994) Cancer Res , vol.54 , pp. 427-436
    • Rowinsky, E.K.1    Grochow, L.B.2    Ettinger, D.S.3    Sartorius, S.E.4    Lubejko, B.G.5    Chen, T.-L.6    Rock, M.K.7    Donehower, R.C.8
  • 17
    • 0028843263 scopus 로고
    • Pharmacological correlation between total drug concentration and lactones of CPT-11 and SN-38 in patients treated with CPT-11
    • Sasaki Y, Yoshida Y, Sudoh K, Hakusui H, Fujii H, Ohtsu T, Wakita H, Igarashi T, Itoh K (1995) Pharmacological correlation between total drug concentration and lactones of CPT-11 and SN-38 in patients treated with CPT-11. Jpn J Cancer Res 86: 111-116
    • (1995) Jpn J Cancer Res , vol.86 , pp. 111-116
    • Sasaki, Y.1    Yoshida, Y.2    Sudoh, K.3    Hakusui, H.4    Fujii, H.5    Ohtsu, T.6    Wakita, H.7    Igarashi, T.8    Itoh, K.9
  • 18
    • 0028364014 scopus 로고
    • Metabolic activation of CPT-11, 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin, a novel antitumor agent, by carboxylesterase
    • Satoh T, Hosokawa M, Atsumi R, Suzuki W, Hakusui H, Nagai E (1994) Metabolic activation of CPT-11, 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin, a novel antitumor agent, by carboxylesterase. Biol Pharm Bull 17: 662-664
    • (1994) Biol Pharm Bull , vol.17 , pp. 662-664
    • Satoh, T.1    Hosokawa, M.2    Atsumi, R.3    Suzuki, W.4    Hakusui, H.5    Nagai, E.6
  • 19
    • 6844265355 scopus 로고
    • Metabolic fate of CPT-11 in beagle dogs after single bolus injection and infusion
    • Suzuki W, Atsumi T, Nakaoka M, Hakusui H (1990) Metabolic fate of CPT-11 in beagle dogs after single bolus injection and infusion (in Japanese). The Clin Rep 24: 219-228
    • (1990) The Clin Rep , vol.24 , pp. 219-228
    • Suzuki, W.1    Atsumi, T.2    Nakaoka, M.3    Hakusui, H.4
  • 21


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.