Real-time in situ monitoring of lysozyme during lyophilization using infrared spectroscopy: Dehydration stress in the presence of sucrose

Pharmaceutical Research

Volumn 14, Issue 11, 1997, Pages 1548-1555

  Remmele Jr , Richard L ^a   Stushnoff, Cecil ^b   Carpenter, John F ^c  

^a AMGEN INC   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

Attenuated total reflectance; FTIR spectroscopy; Internal reflection; Lysozyme; Sucrose

Indexed keywords

LYSOZYME; SUCROSE;

ARTICLE; ENZYME STRUCTURE; FREEZE DRYING; IN VITRO STUDY; INFRARED SPECTROSCOPY; MONITORING; PRIORITY JOURNAL; PROCESS CONTROL; TECHNIQUE;

FREEZE DRYING; MURAMIDASE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STRESS, MECHANICAL; SUCROSE;

EID: 6844241962     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012170116311     Document Type: Article

References (24)

1. S. J. Prestrelski, T. Arakawa, and J. F. Carpenter. Arch. Biochem. Biophys. 303:465-473 (1993).
2. W. R. Liu, R. Langer, and A. M. Klibanov. Biotechnol. Bioeng. 37:177-184 (1991).
3. M. L. Roy, M. J. Pikal, E. C. Rickard, and A. M. Maloney. Dev. Biol. Stand. 74:323-340 (1991).
4. M. J. Pikal. Biopharm 3:27-30 (1990).
5. J. F. Carpenter, T. Arakawa, and J. H. Crowe. Dev. Biol. Stand. 74:225-239 (1991).
6. M. J. Pikal. Biopharm 3:18-27 (1990).
7. R. L. Remmele, Jr. and C. Stushnoff. Biopolymers 34:365-370 (1994).
8. R. L. Remmele, C. Stushnoff, and J. F. Carpenter. Real-time infrared spectroscopic analysis of lysozyme during lyophilization. In Formulation and Delivery of Proteins and Peptides (J. L. Cleland and R. Langer, eds.). American Chemical Society 170-192 (1994).
9. J. C. May, R. M. Wheeler, N. Etz, and A. Del Grosso. Dev. Biol. Stand. 74:153-164 (1991).
10. R. L. Remmele, P. McMillan, and A. Bieber. J. Protein Chem. 9:475-485 (1990).
11. F. Franks, R. H. M. Hatley, and S. F. Mathias. Pharm. Technol. Int. 3:24-34 (1991).
12. M. J. Pikal, S. Shah, M. L. Roy, and R. Putman. Int. Pharmaceutics 60:203-217 (1990).
13. G. Careri, A. Giansanti, and E. Gratton. Biopolymers 18:1187-1203 (1979).
14. B .C. Hancock and G. Zografi. Pharm. Res. 11:471-477 (1994).
15. J. F. Carpenter and J. H. Crowe. Cryobiology 25:244-255 (1988).
16. T. Arakawa, S. J. Prestrelski, W. C. Kenney, and J. F. Carpenter. Adv. Drug Delivery Rev. 10:1-28 (1993).
17. T. Arakawa, Y. Kita, and J. F. Carpenter. Pharm. Res. 8:285-291 (1991).
18. J. F. Carpenter, S. J. Prestrelski, and T. Arakawa. Arch. Biochem. Biophys. 303:456-464 (1993).
19. Y. Liu and D. W. Bolen. Biochemistry 34:12884-12891 (1995).
20. K. Tanaka, T. Takeda, and K. Miyajima. Chem. Pharm. Bull. 39:1091-1094 (1991).
21. P. W. Yang, H. H. Mantsch, J. L. R. Arrondo, I. Saint-Girons, Y. Guillou, G. N. Cohen, and O. Barzu. Biochemistry 26:2706-2711 (1987).
22. A. P. MacKenzie. Dev. Biol. Stand. 36:51-67 (1977).
23. J. F. Carpenter and J. H. Crowe. Biochemistry 28:3916-3922 (1989).
24. J. H. McMinn, M. J. Sowa, S. B. Charnick, and M. E. Paulaitis. Biopolymers 33:1213-1224 (1993).