Expression of acute otitis media after receptor blockade of platelet activating factor, thromboxane, and leukotrienes in the chinchilla

Annals of Otology, Rhinology and Laryngology

Volumn 107, Issue 3, 1998, Pages 199-206

  Diven, Warren F ^a,d   Burckart, Gilbert J ^c   Alper, Cuneyt M ^b   Jaffeh, Ronald ^a   Evans, Rhobert W ^c   Doyle, William J ^b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d NONE

Author keywords

Acute otitis media; Animal model; Inflammatory mediators; Platelet activating factor; Thromboxane

Indexed keywords

AMPICILLIN; APAFANT; LEUKOTRIENE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; THROMBOXANE; THROMBOXANE A2 RECEPTOR BLOCKING AGENT; VAPIPROST; VERLUKAST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHINCHILLA; CONTROLLED STUDY; DOSE RESPONSE; INFLAMMATION; MIDDLE EAR EFFUSION; NONHUMAN; ORAL DRUG ADMINISTRATION; OTITIS MEDIA; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE; THROMBOCYTE ACTIVATION;

EID: 6844240871     PISSN: 00034894     EISSN: None     Source Type: Journal    
DOI: 10.1177/000348949810700303     Document Type: Article

References (32)

1. Vital and Health Statistics. Current estimates from the National Health Interview Survey (publication 90-1504; 20; series 10, No. 176). Hyattsville, Md: US Department of Health and Human Services, 1990.
2. Bluestone CD, Stephenson JS, Martin LM. Ten-year review of otitis media pathogens. Pediatr Infect Dis J 1992;11:S7-S11.
3. Rosenfeld RM, Vertrees JE, Carr J, et al. Clinical efficacy of antimicrobial drugs for acute otitis media: metaanalysis of 5400 children from thirty-three randomized trials. J Pediatr 1994;124:355-67.
4. Bernstein JM, Villari EM, Rattazi MC. The significance of lysosomal enzymes in middle ear effusions. Otolaryngol Head Neck Surg 1979;87:845-51.
5. Boisvert P, Wasserman SI, Schiff M, Ryan AF. Histamine-induced middle ear effusion and mucosal histopathology in the guinea pig. Ann Otol Rhinol Laryngol 1985;94:212-6.
6. DeMaria TF, Briggs BR, Lim DJ, Okazaki N. Experimental otitis media with effusion following middle ear inoculation of nonviable H influenzae. Ann Otol Rhinol Laryngol 1984;93:52-6.
7. Diven WF, Glew RH, Bluestone CD. Lysosomal hydrolases in middle ear effusions. Ann Otol Rhinol Laryngol 1981;90:148-53.
8. Juhn SK, Huff JS. Biochemical characteristics of middle ear effusions. Ann Otol Rhinol Laryngol Suppl 1976;85(suppl 25):110-6.
9. Jung TTK. Arachidonic acid metabolites in otitis media pathogenesis. Ann Otol Rhinol Laryngol Suppl 1988;97(suppl 132):14-8.
10. Harada T, Juhn SK, Adams GL. Lysozyme levels in middle ear effusion and serum in otitis media. Arch Otolaryngol Head Neck Surg 1990;116:54-6.
11. Brodsky L, Faden H, Bernstein J, et al. Arachidonic acid metabolites in middle ear effusions of children. Ann Otol Rhinol Laryngol 1991;100:589-92.
12. Nonomura N, Giebink GS, Zelterman D, Harada T, Juhn SK. Early biochemical events in pneumococcal otitis media: arachidonic acid metabolites in middle ear fluid. Ann Otol Rhinol Laryngol 1991;100:385-8.
13. Jung TTK, Park YM, Schlund D, et al. Effect of prostaglandin, leukotriene, and arachidonic acid on experimental otitis media with effusion in chinchillas. Ann Otol Rhinol Laryngol Suppl 1990;99(suppl 148):28-32.
14. Rhee C-K, Jung TTK, Miller S, Weeks D. Experimental otitis media with effusion induced by platelet activating factor. Ann Otol Rhinol Laryngol 1993;102:600-5.
15. Jung TTK, Giebink GS, Juhn SK. Effects of ibuprofen, corticosteroid, and penicillin on the pathogenesis of experimental pneumococcal otitis media. In: Lim DJ, Bluestone CD, Klein JO, Nelson JD, eds. Recent advances in otitis media. Toronto, Canada: BC Decker, 1984:269-72.
16. Diven WF, Evans RW, Swarts JD, Burckart GJ, Doyle WJ. Effect of ibuprofen treatment during experimental otitis media. Auris Nasus Larynx 1995;22:73-9.
17. Jung TTK, Rhee CK, Park YS, Choi DJ, Miller S, Weeks D. Effect of the inhibitors of leukotriene and platelet-activating factor on killed H influenzae-induced experimental otitis media. In: Mogi G, Honjo I, Ishii T, Takasaka T, eds. Recent advances in otitis media. Proceedings of the Second Extraordinary International Symposium on Recent Advances in Otitis Media, Oita, Japan. Amsterdam, the Netherlands: Kugler Publications, 1994:661-5.
18. Park YS, Jung TTK, Choi DJ, Rhee CK, Richmond T, Weeks D. Effect of blockers of leukotriene and/or platelet activating factor on experimental otitis media with effusion induced by eustachian tube obstruction. In: Mogi G, Honjo I, Ishii T, Takasaka T, eds. Recent advances in otitis media. Proceedings of the Second Extraordinary International Symposium on Recent Advances in Otitis Media, Oita, Japan. Amsterdam, the Netherlands: Kugler Publications, 1994:671-5.
19. Rhee CK, Park YS, Choi DJ, Jung TTK. Effect of inflammatory mediators and their blockers on vascular permeability in experimental otitis media induced by killed H influenzae. In: Mogi G, Honjo I, Ishii T, Takasaka T, eds. Recent advances in otitis media. Proceedings of the Second Extraordinary International Symposium on Recent Advances in Otitis Media, Oita, Japan. Amsterdam, the Netherlands: Kugler Publications, 1994:677-81.
20. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-7.
21. Burkhardt D, Reinauer H. Purification and some properties of an alkaline protease from rat skeletal muscle. Biochem J 1978;171:803-10.
22. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959;37:911-7.
23. Diven WF, Doyle WJ, Vietmeier B. Hydrolase activity in middle ear effusions, effect of antibiotic therapy. Arch Otolaryngol Head Neck Surg 1988;114:52-5.
24. Rosenfeld RM, Doyle WJ, Swarts JD, Pinero BP. Third-generation cephalosporins in the treatment of acute pneumococcal otitis media. An animal study. Arch Otolaryngol Head Neck Surg 1992;118:49-52.
25. Thomas M, Keery RJ, Charter MK, et al. The pharmacodynamics and pharmacokinetics of a novel thromboxane receptor blocking drug Vapiprost (GR32191) after single intravenous doses in healthy subjects. Br J Clin Pharmacol 1991;32:181-6.
26. Jones TR, Zamboni R, Belley M, et al. Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D4 receptor antagonist. Can J Physiol Pharmacol 1989;67:17-28.
27. Casals-Stenzel J, Muacevic G, Weber K. Pharmacological actions of WEB-2086. Anew specific antagonist of platelet activating factor. J Pharmacol Exp Ther 1987;241:974-81.
28. Mitchell JRA. Clinical aspects of the arachidonic acid-thromboxane pathway. Br Med Bull 1983;39:289-95.
29. Whittle BJR, Moncada S. Pharmacological interactions between prostacyclin and thromboxanes. Br Med Bull 1983;39:232-8.
30. Abramovich S, O'Grady J, Fuller A, MacKinnon M, Lavelle R. Naproxen in otitis media with effusion. J Laryngol Otol 1986;100:263-6.
31. Giebink GS, Batalden PB, Le CT, Lassman FM, Buran DJ, Seltz AE. A controlled trial comparing three treatments for chronic otitis media with effusion. Pediatr Infect Dis J 1990;9:33-40.
32. Varsano IB, Volovitz BM, Grossman JE. Effect of naproxen, a prostaglandin inhibitor, on acute otitis media and persistence of middle ear effusion in children. Ann Otol Rhinol Laryngol 1989;98:389-92.