Cerebral hemodynamic predictors of poor 6-month Glasgow outcome score in severe pediatric traumatic brain injury

Journal of Neurotrauma

Volumn 26, Issue 5, 2009, Pages 657-663

  Chaiwat, Onuma ^a   Sharma, Deepak ^a   Udomphorn, Yuthana ^a   Armstead, William M ^b   Vavilala, Monica S ^a,c,d,e  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

^e UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Cerebral autoregulation; Outcome; Pediatric; Traumatic brain injury

Indexed keywords

ADOLESCENT; ARTICLE; AUTOREGULATION; BRAIN; BRAIN PERFUSION; CHILD; CHILDHOOD INJURY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GLASGOW OUTCOME SCALE; HEMODYNAMICS; HUMAN; INTRACRANIAL HYPERTENSION; INTRACRANIAL HYPOTENSION; INTRACRANIAL PRESSURE; MALE; MIDDLE CEREBRAL ARTERY; MULTIVARIATE ANALYSIS; OUTCOME ASSESSMENT; RETROSPECTIVE STUDY; SYSTOLIC BLOOD PRESSURE; TRAUMATIC BRAIN INJURY; UNIVARIATE ANALYSIS; ANALYSIS OF VARIANCE; BLOOD PRESSURE; BRAIN CIRCULATION; BRAIN INJURY; COMPUTER ASSISTED TOMOGRAPHY; HOMEOSTASIS; INFANT; PATHOPHYSIOLOGY; PHYSIOLOGY; PRESCHOOL CHILD; PROGNOSIS; PROSPECTIVE STUDY; RISK FACTOR; TREATMENT OUTCOME; VASCULAR RESISTANCE;

ADOLESCENT; ANALYSIS OF VARIANCE; BLOOD PRESSURE; BRAIN INJURIES; CEREBROVASCULAR CIRCULATION; CHILD; CHILD, PRESCHOOL; FEMALE; GLASGOW OUTCOME SCALE; HOMEOSTASIS; HUMANS; INFANT; MALE; MIDDLE CEREBRAL ARTERY; PROGNOSIS; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; RISK FACTORS; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME; VASCULAR RESISTANCE;

EID: 68349158160     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2008.0770     Document Type: Article

References (29)

1. Adelson, P.D., Bratton, S.L., Carney, N.A., Chesnut, R.M., du Coudray, H.E., Goldstein, B., Kochanek, P.M., Miller, H.C., Partington, M.D., Selden, N.R., Warden, C.R., and Wright, D.W. (2003). Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 4. Resuscitation of blood pressure and oxygenation and prehospital brain-specific therapies for the severe pediatric traumatic brain injury patient. Pediatr. Crit. Care Med. 4, S12-S18.
2. Adelson, P.D., Clyde, B., Kochanek, P.M., Wisniewski, S.R., Marion, D.W., and Yonas, H. (1997). Cerebrovascular response in infants and young children following severe traumatic brain injury: a preliminary report. Pediatr. Neurosurg. 26, 200-207.
3. Adelson, P.D., Bratton, S.L., Carney, N.A., Chesnut, R.M., du Coudray, H.E., Goldstein, B., Kochanek, P.M., Miller, H.C., Partington, M.D., Selden, N.R., Warden, C.R., and Wright, D.W. (2003). Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 8. Cerebral perfusion pressure. Pediatr. Crit. Care Med. 4, Suppl, S31-S33.
4. Bode, H. (1988). Application of Pediatric Transcranial Doppler Ultrasonography. Springer-Verlag: New York.
5. Catala-Temprano, A., Claret-Teruel, G., Cambra-Lasaosa F.J., Pons-Odena, M., Noguera-Julian A., and Palomeque-Rico, A. (2007). Intracranial pressure and cerebral perfusion pressure as risk factors in children with traumatic brain injuries. J. Neurosurg. 106, 463-466.
6. Coates, B.M., Vavilala, M.S., Mack, C.D., Muangman, S., Suz, P., Sharar, S.R., Bulger, E., and Lam, A.M. (2005). Influence of definition and location of hypotension on outcome following severe pediatric traumatic brain injury. Crit. Care Med. 33, 2645-2650.
7. Downard, C., Hulka, F., Mullins, R.J., Piatt, J., Chesnut, R., Quint, P., and Mann, N.C. (2000). Relationship of cerebral perfusion pressure and survival in pediatric brain-injured patients. J. Trauma 49, 654-658.
8. Elias-Jones, A.C., Punt, J.A., Turnbull, A.E., and Jaspan, T. (1992). Management and outcome of severe head injuries in the Trent region 1985-90. Arch. Dis. Child. 67, 1430-1435.
9. Jennett, B., Teasdale, G., Braakman, R., Minderhoud, J., Heiden, J., and Kurze, T. (1979). Prognosis of patients with severe head injury. Neurosurgery 4, 283-289. (Pubitemid 9157485)
10. Kokoska, E.R, Smith, G.S, Pittman, T., and Weber, T.R. (1998). Early hypotension worsens neurological outcome in pediatric patients with moderately severe head trauma. J. Pediatr. Surg. 33, 333-338.
11. Langlois, J.A. (2001). Traumatic Brain Injury in the United States: Assessing Outcomes in Children. National Center for Injury Prevention and Control, Centers for Disease Control and Prevention (CDC): Atlanta.
12. Luerrsen, T.G., Klauber, M.R., and Marshall, L.F. (1988). Outcome from head injury related to patient's age: a longitudinal prospective study of adult and pediatric study of adult and pediatric head injury. J. Neurosurg. 68, 409-416.
13. Marion, D.W., Darby, J., and Yonas, H. (1991). Acute regional cerebral blood flow changes caused by severe head injuries. J. Neurosurg. 74, 407-414.
14. Muizelaar, J.P., Ward, J.D., Marmarou, A., Newlon, P.G., and Wachi, A. (1989). Cerebral blood flow and metabolism in severely head-injured children. Part 2: Autoregulation. J. Neurosurg. 71, 72-76.
15. Muizelaar, J.P., Marmarou, A., DeSalles, A.A., Ward, J.D., Zimmerman, R.S., Li, Z., Choi, S.C., and Young, H.F. (1989). Cerebral blood flow and metabolism in severely head-injured children. Part 1: Relationship with GCS score, outcome, ICP, and PVI. J. Neurosurg. 71, 63-71.
16. Nakayama, D.K., Copes, W.S., and Sacco, W.J. (1991). The effect of patient age upon survival in pediatric trauma. J. Trauma 31, 1521-1526.
17. Newell, D.W., Weber, J.P., Watson, R., Aaslid, R., and Winn, H.R. (1996). Effect of transient moderate hyperventilation on dynamic cerebral autoregulation after severe head injury. Neurosurgery 39, 35-43. (Pubitemid 26230456)
18. Pigula, F.A., Wald, S.L., Shackford, S.R., and Vane, D.W. (1993). The effect of hypotension and hypoxia on children with severe head injuries. J. Pediatr. Surg. 28, 310-314.
19. Puppo, C., Lopez. L., Farina, G., Caragna, E., Moraes, L., Iturralde, A., and Biestro, A. (2007). Indomethacin and cerebral autoregulation in severe head injured patients: a transcranial Doppler study. Acta Neurochir. (Wien) 149, 139-149.
20. Samant, U.B., Mack, C.D., Koepsell, T., Rivara, F.P., and Vavilala, M.S. (2008). Time of hypotension and discharge outcome in children with severe traumatic brain injury. J. Neurotrauma 25, 495-502. (Pubitemid 351685493)
21. Sharples, P.M., Matthews, D.S., and Eyre, J.A. (1995). Cerebral blood flow and metabolism in children with severe head injuries. Part 2: Cerebrovascular resistance and its determinants. J. Neurol. Neurosurg. Psychiatry 58, 153-159.
22. Strebel, S., Lam, A.M., Matta, B., Mayberg, T.S., Aaslid, R., and Newell, D.W. (1995). Dynamic and static cerebral autoregulation during isoflurane, desflurane, and propofol anesthesia. Anesthesiology 83, 66-76.
23. Tontisirin, N., Armstead, W., Waitayawinyu, P., Moore, A., Udomphorn, Y., Zimmerman, J.J., Chesnut, R., and Vavilala, M.S. (2007). Change in cerebral autoregulation as a function of time in children after severe traumatic brain injury: a case series. Childs Nerv. Syst. 23, 1163-1169.
24. Udomphorn, Y., Armstead, W.M., and Vavilala, M.S. (2008). Cerebral blood flow and autoregulation after pediatric traumatic brain injury. Pediatr. Neurol. 38, 225-234.
25. Vavilala, M.S., Bowen, A., Lam, A.M., Uffman, J.C., Powell, J., Winn, H.R., and Rivara, F.P. (2003). Blood pressure and outcome after severe pediatric traumatic brain injury. J. Trauma 55, 1039-1044. (Pubitemid 38044118)
26. Vavilala, M.S., Dunbar, P.J., Rivara, F.P., and Lam, A.M. (2001). Coagulopathy predicts poor outcome following head injury in children less than 16 years of age. J. Neurosurg. Anesthesiol. 13, 13-18.
27. Vavilala, M.S., Lee, L.A., Boddu, K., Visco, E., Newell, D.W., Zimmerman, J.J., and Lam, A.M. (2004). Cerebral autoregulation in pediatric traumatic brain injury. Pediatr. Crit. Care Med. 5, 257-263.
28. Vavilala, M.S., Muangman, S., Tontisirin, N., Fisk, D., Roscigno, C., Mitchell, P., Kirkness, C., Zimmerman, J.J., Chesnut, R., and Lam, A.M. (2006). Impaired cerebral autoregulation and 6-month outcome in children with severe traumatic brain injury: preliminary findings. Dev. Neurosci. 28, 348-353.
29. Vavilala, M.S, Tontisirin, N., Udomphorn, Y., Armstead, W., Zimmerman, J.J., Chesnut, R., and Lam, A.M. (2008). Hemispheric differences in cerebral autoregulation in children with moderate and severe traumatic brain injury. Neurocrit. Care 9, 45-54.