Molecular analysis of the apoptotic effects of BPA in acute myeloid leukemia cells

Journal of Translational Medicine

Volumn 7, Issue , 2009, Pages

  Bontempo, Paola ^a,b   Mita, Luigi ^a,b   Doto, Antonella ^a   Miceli, Marco ^a   Nebbioso, Angela ^a   Lepore, Ilaria ^a   Franci, GianLuigi ^a   Menafra, Roberta ^a   Carafa, Vincenzo ^a   Conte, Mariarosaria ^a   De Bellis, Floriana ^a   Manzo, Fabio ^a   Di Cerbo, Vincenzo ^a   Benedetti, Rosaria ^c   D'Amato, Loredana ^a   Marino, Maria ^b,d   Bolli, Alessandro ^b,d   Del Pozzo, Giovanna ^b,e   Diano, Nadia ^a,b,e   Portaccio, Marianna ^a,b   Mita, Gustavo D ^a,c   Vietri, Maria Teresa ^a   Cioffi, Michele ^a   Nola, Ernesto ^a   Dell'Aversana, Carmela ^a   Sica, Vincenzo ^a   Molinari, Anna Maria ^a   Altucci, Lucia ^a,b   more..

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b Istituto Nazionale di Biostruttura e dei Biosistemi   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d ROMA TRE UNIVERSITY   (Italy)

^e INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; CASPASE 37; CASPASE 8; CASPASE 9; EFFECTOR CASPASE; FAS ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAD; PROTEIN KINASE B; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; BAD PROTEIN, HUMAN; CASPASE; GLYCOPROTEIN P 15095; PHENOL DERIVATIVE; SCAVENGER;

ACETYLATION; ACUTE GRANULOCYTIC LEUKEMIA; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE REGULATION; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; GENE CONTROL; HUMAN; HUMAN CELL; LEUKEMIA CELL; PROTEIN PHOSPHORYLATION; TOXICITY TESTING; WESTERN BLOTTING; CELL DEATH; CELL STRAIN HL 60; DOSE RESPONSE; DRUG EFFECT; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TIME; TUMOR CELL CULTURE;

ANTIGENS, CD11C; ANTIGENS, CD95; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; CASPASES; CELL DEATH; CELL DIFFERENTIATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FREE RADICAL SCAVENGERS; HL-60 CELLS; HUMANS; LEUKEMIA, MYELOID, ACUTE; PHENOLS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; TIME FACTORS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED;

EID: 68349146184     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-7-48     Document Type: Article

References (23)

1. Colborn T vom Saal FS Soto AM Developmental effects of endocrine-disrupting chemicals in wildlife and humans Environ Health Perspect 1993, 101:378-384 10.2307/3431890 1519860 8080506
2. Vandelac L Endocrine disruption agents: Environment, health, public policies, and the precautionary principle Bull Acad Natl Med 2000, 184:1477-1486 discussion 14871490 11261252
3. Vasseur P Cossu-Leguille C Linking molecular interactions to consequent effects of persistent organic pollutants (POPs) upon populations Chemosphere 2006, 62:1033-1042 10.1016/j.chemosphere.2005.05.043 16055165
4. Cheek AO Kow K Chen J McLachlan JA Potential mechanisms of thyroid disruption in humans: Interaction of organochlorine compounds with thyroid receptor, transthyretin, and thyroid-binding globulin Environ Health Perspect 1999, 107:273-278 10.2307/3434593 1566512 10090705
5. Welshons WV Thayer KA Judy BM Taylor JA Curran EM vom Saal FS Large effects from small exposures. I. Mechanisms for endocrine-disrupting chemicals with estrogenic activity Environ Health Perspect 2003, 111:994-1006 1241550 12826473
6. Kang JH Kondo F Katayama Y Human exposure to bisphenol A Toxicology 2006, 226:79-89 10.1016/j.tox.2006.06.009 16860916
7. Vandenberg LN Hauser R Marcus M Olea N Welshons WV Human exposure to bisphenol A (BPA) Reprod Toxicol 2007, 24:139-177 10.1016/ j.reprotox.2007.07.010 17825522
8. Durando M Kass L Piva J Sonnenschein C Soto AM Luque EH Munoz-de-Toro M Prenatal bisphenol A exposure induces preneoplastic lesions in the mammary gland in Wistar rats Environ Health Perspect 2007, 115:80-86 1797838 17366824
9. Howdeshell KL Hotchkiss AK Thayer KA Vandenbergh JG vom Saal FS Exposure to bisphenol A advances puberty Nature 1999, 401:763-764 10.1038/44517 10548101
10. Howdeshell KL Wilson VS Furr J Lambright CR Rider CV Blystone CR Hotchkiss AK Gray LE Jr et al A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive manner Toxicol Sci 2008, 105:153-165 10.1093/toxsci/kfn077 18411233
11. Kubo K Arai O Ogata R Omura M Hori T Aou S et al Exposure to bisphenol A during the fetal and suckling periods disrupts sexual differentiation of the locus coeruleus and of behavior in the rat Neurosci Lett 2001, 304:73-76 10.1016/S0304-3940(01)01760-8 11335058
12. Kubo K Arai O Omura M Watanabe R Ogata R Aou S Low dose effects of bisphenol A on sexual differentiation of the brain and behavior in rats Neurosci Res 2003, 45:345-356 10.1016/S0168-0102(02)00251-1 12631470
13. Richter CA Birnbaum LS Farabollini F Newbold RR Rubin BS Talsness CE Vandenbergh JG Walser-Kuntz DR vom Saal FS In vivo effects of bisphenol A in laboratory rodent studies Reprod Toxicol 2007, 24:199-224 10.1016/ j.reprotox.2007.06.004 2151845 17683900
14. Rubin BS Lenkowski JR Schaeberle CM Vandenberg LN Ronsheim PM Soto AM Evidence of altered brain sexual differentiation in mice exposed perinatally to low, environmentally relevant levels of bisphenol A Endocrinology 2006, 147:3681-3691 10.1210/en.2006-0189 16675520
15. Schonfelder G Flick B Mayr E Talsness C Paul M Chahoud I In utero exposure to low doses of bisphenol A lead to long-term deleterious effects in the vagina Neoplasia 2002, 4:98-102 10.1038/sj.neo.7900212 1550317 11896564
16. Timms BG Howdeshell KL Barton L Bradley S Richter CA vom Saal FS et al Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra Proc Natl Acad Sci USA 2005, 102:7014-7019 10.1073/pnas.0502544102 1088066,1088066 15867144
17. Terasaka H Kadoma Y Sakagami H Fujisawa S Cytotoxicity and apoptosis-inducing activity of bisphenol A and hydroquinone in HL-60 cells Anticancer Res 2005, 25:2241-2247 16158970
18. Terasaka H Morshed SR Hashimoto K Sakagami H Fujisawa S Hydroquinone-induced apoptosis in HL-60 cells Anticancer Res 2005, 25:161-170 15816534
19. Scognamiglio A Nebbioso A Manzo F Valente S Mai A Altucci L HDAC-class II specific inhibition involves HDAC proteasome-dependent degradation mediated by RANBP2 Biochim Biophys Acta 2008, 1783:2030-2038 10.1016/ j.bbamcr.2008.07.007 18691615
20. Altucci L Rossin A Raffelsberger W Reitmair A Chomienne C Gronemeyer H Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL Nat Med 2001, 7:680-686 10.1038/89050 11385504
21. Nebbioso A Clarke N Voltz E Germain E Ambrosino C Bontempo P Alvarez R Schiavone EM Ferrara F Bresciani F Weisz A de Lera AR Gronemeyer H Altucci L Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells Nat Med 2005, 11:77-84 10.1038/ nm1161 15619633
22. Mai A Valente S Nebbioso A Simeoni S Ragno R Massa S Brosch G De Bellis F Manzo F Altucci L New pyrrole-based histone deacetylase inhibitors: Binding mode, enzyme- and cell-based investigations Int J Biochem Cell Biol 2009, 41:235-247 10.1016/j.biocel.2008.09.002 18834955
23. Mai A Cheng D Bedford MT Valente S Nebbioso A Perrone A Brosch G Sbardella G De Bellis F Miceli M Altucci L epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors J Med Chem 2008, 51:2279-2290 10.1021/jm701595q 18348515