Vaginal versus sublingual misoprostol for second-trimester pregnancy termination and effect on Doppler measurements

International Journal of Gynecology and Obstetrics

Volumn 106, Issue 3, 2009, Pages 250-253

  Karsidag, A Yasemin Karageyim ^a   Buyukbayrak, Esra E ^a   Kars, Bulent ^a   Dansuk, Ramazan ^a   Unal, Orhan ^a   Turan, M Cem ^a  

^a DR LUTFI KIRDAR KARTAL EDUCATION AND RESEARCH HOSPITAL   (Turkey)

Author keywords

Doppler measurement; Second trimester termination; Sublingual misoprostol; Vaginal misoprostol

Indexed keywords

MISOPROSTOL; OXYTOCIN;

ARTICLE; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOPPLER FLOWMETRY; FEMALE; FEVER; GESTATIONAL AGE; HEADACHE; HUMAN; LABOR INDUCTION; MATERNAL AGE; NAUSEA; PARITY; PATIENT MONITORING; POSTPARTUM HEMORRHAGE; PREGNANCY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SECOND TRIMESTER ABORTION; SINGLE BLIND PROCEDURE; TACHYCARDIA; TASTE DISORDER; UMBILICAL ARTERY; UMBILICAL CORD BLOOD FLOW; UTERUS BLOOD FLOW; VOMITING;

ABORTIFACIENT AGENTS, NONSTEROIDAL; ABORTION, INDUCED; ADMINISTRATION, INTRAVAGINAL; ADMINISTRATION, SUBLINGUAL; BLOOD FLOW VELOCITY; FEMALE; HUMANS; LASER-DOPPLER FLOWMETRY; MISOPROSTOL; PREGNANCY; PREGNANCY TRIMESTER, SECOND; REGIONAL BLOOD FLOW; TREATMENT OUTCOME; UMBILICAL ARTERIES; UTERUS;

EID: 68349139747     PISSN: 00207292     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijgo.2009.04.001     Document Type: Article

References (19)

1. Vimala N., Dadhwal V., and Mittal S. Sublingual misoprostol for second-trimester abortion. Int J Gynecol Obstet 84 1 (2004) 89-90
2. Scheepers H.C., van Erp E.J., and van den Bergh A.S. Use of misoprostol in first and second trimester abortion: a review. Obstet Gynecol Surv 54 9 (1999) 592-600
3. Feldman D.M., Borgida A.F., Rodis J.F., Leo M.V., and Campbell W.A. A randomized comparison of two regimens of misoprostol for second-trimester pregnancy termination. Am J Obstet Gynecol 189 3 (2003) 710-713
4. Tang O.S., Lau W.N., Chan C.C., and Ho P.C. A prospective randomised comparison of sublingual and vaginal misoprostol in second trimester termination of pregnancy. BJOG 111 9 (2004) 1001-1005
5. Caliskan E., Dilbaz S., Doger E., Ozeren S., and Dilbaz B. Randomized comparison of 3 misoprostol protocols for abortion induction at 13-20 weeks of gestation. J Reprod Med 50 3 (2005) 173-180 Erratum in: J Reprod Med 2005;50(9):732
6. Tang O.S., Schweer H., Seyberth H.W., Lee S.W., and Ho P.C. Pharmacokinetics of different routes of administration of misoprostol. Hum Reprod 17 2 (2002) 332-336
7. Wagaarachchi P.T., Ashok P.W., Smith N.C., and Templeton A. Medical management of early fetal demise using sublingual misoprostol. BJOG 109 4 (2002) 462-465
8. Turan C., Koc N., Dansuk R., Cengizoglu B., Mericeli D.S., and Unal O. Misoprostol administration in first-trimester pregnancies with embryonic demise reduces uterine arterial blood flow. J Matern Fetal Neonatal Med 14 4 (2003) 226-228
9. Yip S.K., Tse A.O., Haines C.J., and Chung T.K. Misoprostol's effect on uterine arterial blood flow and fetal heart rate in early pregnancy. Obstet Gynecol 95 2 (2000) 232-235
10. Urban R., Lemancewicz A., Urban J., Skotnicki M.Z., and Kretowska M. Misoprostol and dinoprostone therapy for labor induction: a Doppler comparison of uterine and fetal hemodynamic effects. Eur J Obstet Gynecol Reprod Biol 106 1 (2003) 20-24
11. Wang Z., Li W., and Ouyang W. Safety and efficacy of intravaginal misoprostol for cervical ripening in the third trimester of pregnancy [In Chinese]. Zhonghua Fu Chan Ke Za Zhi 32 6 (1997) 326-328
12. Chang C.H., and Chang F.M. Randomized comparison of misoprostol and dinoprostone for preinduction cervical ripening and labor induction. J Formos Med Assoc 96 5 (1997) 366-369
13. Tang O.S., Chan C.C., Ng E.H., Lee S.W., and Ho P.C. A prospective, randomized, placebo-controlled trial on the use of mifepristone with sublingual or vaginal misoprostol for medical abortions of less than 9 weeks gestation. Hum Reprod 18 11 (2003) 2315-2318
14. Borgida A.F., Rodis J.F., Hanlon W., Craffey A., Ciarleglio L., and Campbell W.A. Second-trimester abortion by intramuscular 15-methyl-prostaglandin F2 alpha or intravaginal prostaglandin E2 suppositories: a randomized trial. Obstet Gynecol 85 5 Pt 1 (1995) 697-700
15. Ho P.C., Ngai S.W., Liu K.L., Wong G.C., and Lee S.W. Vaginal misoprostol compared with oral misoprostol in termination of second-trimester pregnancy. Obstet Gynecol 90 5 (1997) 735-738
16. Bhattacharjee N., Saha S.P., Ghoshroy S.C., Bhowmik S., and Barui G. A randomised comparative study on sublingual versus vaginal administration of misoprostol for termination of pregnancy between 13 to 20 weeks. Aust N Z J Obstet Gynaecol 48 2 (2008) 165-171
17. Okanlomo K.A., Ngotho D., and Moodley J. Effect of misoprostol for cervical ripening prior to pregnancy interruption before twelve weeks of gestation. East Afr Med J 76 10 (1999) 552-555
18. Aronsson A., Helström L., and Gemzell-Danielsson K. Sublingual compared with oral misoprostol for cervical dilatation prior to vacuum aspiration: a randomized comparison. Contraception 69 2 (2004) 165-169
19. Lemancewicz A., Urban R., Skotnicki M.Z., Karpiuk A., and Urban J. Uterine and fetal Doppler flow changes after misoprostol and oxytocin therapy for induction of labor in post-term pregnancies. Int J Gynecol Obstet 67 3 (1999) 139-145