-
1
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal A., Siegel R., Ward E., et al. Cancer statistics, 2008. CA Cancer J Clin 58 (2008) 71-96
-
(2008)
CA Cancer J Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
2
-
-
51549117737
-
SEER Cancer statistics review, 1975-2005, National Cancer Institute. Bethesda, MD
-
based on November SEER data submission, posted to the SEER web site;
-
Ries LAG, Melbert D, Krapcho M et al. SEER Cancer statistics review, 1975-2005, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2005/, based on November 2007 SEER data submission, posted to the SEER web site; 2008.
-
(2007)
-
-
Ries, L.A.G.1
Melbert, D.2
Krapcho, M.3
-
3
-
-
0016740933
-
Clinical staging of chronic lymphocytic leukemia
-
Rai K.R., Sawitsky A., Cronkite E.P., Chanana A.D., Levy R.N., and Pasternack B.S. Clinical staging of chronic lymphocytic leukemia. Blood 46 (1975) 219-234
-
(1975)
Blood
, vol.46
, pp. 219-234
-
-
Rai, K.R.1
Sawitsky, A.2
Cronkite, E.P.3
Chanana, A.D.4
Levy, R.N.5
Pasternack, B.S.6
-
4
-
-
0017751562
-
A clinical staging system for chronic lymphocytic leukemia: prognostic significance
-
Binet J.L., Leporrier M., Dighiero G., et al. A clinical staging system for chronic lymphocytic leukemia: prognostic significance. Cancer 40 (1977) 855-864
-
(1977)
Cancer
, vol.40
, pp. 855-864
-
-
Binet, J.L.1
Leporrier, M.2
Dighiero, G.3
-
5
-
-
45149100665
-
Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the international workshop on chronic lymphocytic leukemia updating the National Cancer Institute-working group 1996 guidelines
-
Hallek M., Cheson B.D., Catovsky D., et al. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the international workshop on chronic lymphocytic leukemia updating the National Cancer Institute-working group 1996 guidelines. Blood 111 (2008) 5446-5456
-
(2008)
Blood
, vol.111
, pp. 5446-5456
-
-
Hallek, M.1
Cheson, B.D.2
Catovsky, D.3
-
6
-
-
43949132083
-
New prognostic markers in chronic lymphocytic leukemia
-
Moreno C., and Montserrat E. New prognostic markers in chronic lymphocytic leukemia. Blood Rev 22 (2008) 211-219
-
(2008)
Blood Rev
, vol.22
, pp. 211-219
-
-
Moreno, C.1
Montserrat, E.2
-
7
-
-
33947544426
-
Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997
-
Grever M.R., Lucas D.M., Dewald G.W., et al. Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997. J Clin Oncol 25 (2007) 799-804
-
(2007)
J Clin Oncol
, vol.25
, pp. 799-804
-
-
Grever, M.R.1
Lucas, D.M.2
Dewald, G.W.3
-
8
-
-
34447530283
-
Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): a randomised controlled trial
-
Catovsky D., Richards S., Matutes E., et al. Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): a randomised controlled trial. Lancet 370 (2007) 230-239
-
(2007)
Lancet
, vol.370
, pp. 230-239
-
-
Catovsky, D.1
Richards, S.2
Matutes, E.3
-
9
-
-
68349134062
-
-
Stilgenbauer S, Zenz T, Winkler D et al. Genomic aberrations, VH mutation status and outcome after fludarabine and cyclophosphamide (FC) or FC plus rituximab in the CLL8 Trial [abstract]. Blood (ASH Annual Meeting Abstracts) 2008;112: Abstract 781.
-
Stilgenbauer S, Zenz T, Winkler D et al. Genomic aberrations, VH mutation status and outcome after fludarabine and cyclophosphamide (FC) or FC plus rituximab in the CLL8 Trial [abstract]. Blood (ASH Annual Meeting Abstracts) 2008;112: Abstract 781.
-
-
-
-
10
-
-
0344729013
-
Chlorambucil in indolent chronic lymphocytic leukemia. French cooperative group on chronic lymphocytic leukemia
-
Dighiero G., Maloum K., Desablens B., et al. Chlorambucil in indolent chronic lymphocytic leukemia. French cooperative group on chronic lymphocytic leukemia. N Engl J Med 338 (1998) 1506-1514
-
(1998)
N Engl J Med
, vol.338
, pp. 1506-1514
-
-
Dighiero, G.1
Maloum, K.2
Desablens, B.3
-
11
-
-
40249091469
-
Controversies in the front-line management of chronic lymphocytic leukemia
-
Nabhan C., Shanafelt T.D., and Kay N.E. Controversies in the front-line management of chronic lymphocytic leukemia. Leukemia Res 32 (2008) 679-688
-
(2008)
Leukemia Res
, vol.32
, pp. 679-688
-
-
Nabhan, C.1
Shanafelt, T.D.2
Kay, N.E.3
-
12
-
-
61449135843
-
Treatment of elderly patients with chronic lymphocytic leukemia
-
Eichhorst B., Goede V., and Hallek M. Treatment of elderly patients with chronic lymphocytic leukemia. Leukemia Lymphoma 52 (2009) 171-178
-
(2009)
Leukemia Lymphoma
, vol.52
, pp. 171-178
-
-
Eichhorst, B.1
Goede, V.2
Hallek, M.3
-
13
-
-
68349156330
-
-
Eichhorst BF, Busch R, Stauch M et al. No significant clinical benefit of first line therapy with fludarabine in comparison to chlorambucil in elderly patients with advanced chronic lymphocytic leukemia: Results of a phase III study of the German CLL Study Group [abstract]. Blood (ASH Annual Meeting Abstracts) 2007;110: Abstract 629.
-
Eichhorst BF, Busch R, Stauch M et al. No significant clinical benefit of first line therapy with fludarabine in comparison to chlorambucil in elderly patients with advanced chronic lymphocytic leukemia: Results of a phase III study of the German CLL Study Group [abstract]. Blood (ASH Annual Meeting Abstracts) 2007;110: Abstract 629.
-
-
-
-
14
-
-
33947541773
-
Phase III trial of fludarabine plus cyclophosphamide compared with fludarabine for patients with previously untreated chronic lymphocytic leukemia: US intergroup trial E2997
-
Flinn I.W., Neuberg D.S., Grever M.R., et al. Phase III trial of fludarabine plus cyclophosphamide compared with fludarabine for patients with previously untreated chronic lymphocytic leukemia: US intergroup trial E2997. J Clin Oncol 25 (2007) 793-798
-
(2007)
J Clin Oncol
, vol.25
, pp. 793-798
-
-
Flinn, I.W.1
Neuberg, D.S.2
Grever, M.R.3
-
15
-
-
31544434508
-
Fludarabine plus cyclophosphamide versus fludarabine alone in first-line therapy of younger patients with chronic lymphocytic leukemia
-
Eichhorst B.F., Busch R., Hopfinger G., et al. Fludarabine plus cyclophosphamide versus fludarabine alone in first-line therapy of younger patients with chronic lymphocytic leukemia. Blood 107 (2006) 885-891
-
(2006)
Blood
, vol.107
, pp. 885-891
-
-
Eichhorst, B.F.1
Busch, R.2
Hopfinger, G.3
-
16
-
-
19944429446
-
Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: an updated retrospective comparative analysis of CALGB 9712 and CALGB 9011
-
Byrd J.C., Rai K., Peterson B.L., et al. Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: an updated retrospective comparative analysis of CALGB 9712 and CALGB 9011. Blood 105 (2005) 49-53
-
(2005)
Blood
, vol.105
, pp. 49-53
-
-
Byrd, J.C.1
Rai, K.2
Peterson, B.L.3
-
17
-
-
51649093353
-
Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia
-
Tam C.S., O'Brien S., Wierda W., et al. Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia. Blood 112 (2008) 975-980
-
(2008)
Blood
, vol.112
, pp. 975-980
-
-
Tam, C.S.1
O'Brien, S.2
Wierda, W.3
-
18
-
-
74549145611
-
Rituximab, fludarabine, cyclophosphamide, and mitoxantrone (R-FCM) a new, highly active chemoimmunotherapy regimen for chronic lymphocytic leukemia
-
in press
-
Bosch F, Abrisqueta P, Villamor N et al. Rituximab, fludarabine, cyclophosphamide, and mitoxantrone (R-FCM) a new, highly active chemoimmunotherapy regimen for chronic lymphocytic leukemia. J Clin Oncol, in press.
-
J Clin Oncol
-
-
Bosch, F.1
Abrisqueta, P.2
Villamor, N.3
-
19
-
-
68349140276
-
-
Hallek M, Fingerle-Rowson G, Fink A-M et al. Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab versus fludarabine and cyclophosphamide improves response rates and progression-free survival in previously untreated patients with advanced chronic lymphocytic leukaemia [abstract]. Blood (ASH Annual Meeting Abstracts) 2008;112: Abstract 325.
-
Hallek M, Fingerle-Rowson G, Fink A-M et al. Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab versus fludarabine and cyclophosphamide improves response rates and progression-free survival in previously untreated patients with advanced chronic lymphocytic leukaemia [abstract]. Blood (ASH Annual Meeting Abstracts) 2008;112: Abstract 325.
-
-
-
-
20
-
-
33846258434
-
Combination chemoimmunotherapy with pentostatin, cyclophosphamide, and rituximab shows significant clinical activity with low accompanying toxicity in previously untreated B chronic lymphocytic leukemia
-
Kay N.E., Geyer S.M., Call T.G., et al. Combination chemoimmunotherapy with pentostatin, cyclophosphamide, and rituximab shows significant clinical activity with low accompanying toxicity in previously untreated B chronic lymphocytic leukemia. Blood 109 (2007) 405-411
-
(2007)
Blood
, vol.109
, pp. 405-411
-
-
Kay, N.E.1
Geyer, S.M.2
Call, T.G.3
-
21
-
-
59149106873
-
Sequential therapy with fludarabine, high-dose cyclophosphamide, and rituximab in previously untreated patients with chronic lymphocytic leukemia produces high-quality responses: molecular remissions predict for durable complete responses
-
Lamanna N., Jurcic J.G., Noy A., et al. Sequential therapy with fludarabine, high-dose cyclophosphamide, and rituximab in previously untreated patients with chronic lymphocytic leukemia produces high-quality responses: molecular remissions predict for durable complete responses. J Clin Oncol 27 (2009) 491-497
-
(2009)
J Clin Oncol
, vol.27
, pp. 491-497
-
-
Lamanna, N.1
Jurcic, J.G.2
Noy, A.3
-
22
-
-
59149090791
-
Chemoimmunotherapy with low-dose fludarabine and cyclophosphamide and high dose rituximab in previously untreated patients with chronic lymphocytic leukemia
-
Foon K.A., Boyiadzis M., Land S.R., et al. Chemoimmunotherapy with low-dose fludarabine and cyclophosphamide and high dose rituximab in previously untreated patients with chronic lymphocytic leukemia. J Clin Oncol 27 (2009) 498-503
-
(2009)
J Clin Oncol
, vol.27
, pp. 498-503
-
-
Foon, K.A.1
Boyiadzis, M.2
Land, S.R.3
-
23
-
-
0034649696
-
Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia
-
Rai K.R., Peterson B.L., Appelbaum F.R., et al. Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia. N Engl J Med 343 (2000) 1750-1757
-
(2000)
N Engl J Med
, vol.343
, pp. 1750-1757
-
-
Rai, K.R.1
Peterson, B.L.2
Appelbaum, F.R.3
-
24
-
-
37649004407
-
Alemtuzumab compared with chlorambucil as first-line therapy for chronic lymphocytic leukemia
-
Hillmen P., Skotnicki A.B., Robak T., et al. Alemtuzumab compared with chlorambucil as first-line therapy for chronic lymphocytic leukemia. J Clin Oncol 25 (2007) 5616-5623
-
(2007)
J Clin Oncol
, vol.25
, pp. 5616-5623
-
-
Hillmen, P.1
Skotnicki, A.B.2
Robak, T.3
-
25
-
-
40749128044
-
Fludarabine, cyclophosphamide, and mitoxantrone as initial therapy of chronic lymphocytic leukemia: high response rate and disease eradication
-
Bosch F., Ferrer A., Villamor N., et al. Fludarabine, cyclophosphamide, and mitoxantrone as initial therapy of chronic lymphocytic leukemia: high response rate and disease eradication. Clin Cancer Res 14 (2008) 155-161
-
(2008)
Clin Cancer Res
, vol.14
, pp. 155-161
-
-
Bosch, F.1
Ferrer, A.2
Villamor, N.3
-
26
-
-
30744448409
-
A retrospective comparison of three sequential groups of patients with recurrent/refractory chronic lymphocytic leukemia treated with fludarabine-based regimens
-
Wierda W., O'Brien S., Faderl S., et al. A retrospective comparison of three sequential groups of patients with recurrent/refractory chronic lymphocytic leukemia treated with fludarabine-based regimens. Cancer 106 (2006) 337-345
-
(2006)
Cancer
, vol.106
, pp. 337-345
-
-
Wierda, W.1
O'Brien, S.2
Faderl, S.3
-
27
-
-
18744409028
-
Fludarabine, cyclophosphamide and mitoxantrone in the treatment of resistant or relapsed chronic lymphocytic leukaemia
-
Bosch F., Ferrer A., López-Guillermo A., et al. Fludarabine, cyclophosphamide and mitoxantrone in the treatment of resistant or relapsed chronic lymphocytic leukaemia. Br J Haematol 119 (2002) 976-984
-
(2002)
Br J Haematol
, vol.119
, pp. 976-984
-
-
Bosch, F.1
Ferrer, A.2
López-Guillermo, A.3
-
28
-
-
68349151378
-
-
Robak T, Moiseev SI, Dmoszynska A et al. Rituximab plus fludarabine and cyclophosphamide prolongs progression free survival in relapsed or refractory chronic lymphocytic leukaemia compared with FC alone: Final results from the International Randomized Phase III REACH Trial [abstract]. Blood (ASH Annual Meeting Abstracts) 2008;112: Abstract lba-1.
-
Robak T, Moiseev SI, Dmoszynska A et al. Rituximab plus fludarabine and cyclophosphamide prolongs progression free survival in relapsed or refractory chronic lymphocytic leukaemia compared with FC alone: Final results from the International Randomized Phase III REACH Trial [abstract]. Blood (ASH Annual Meeting Abstracts) 2008;112: Abstract lba-1.
-
-
-
-
29
-
-
33645732715
-
Pentostatin, cyclophosphamide, and rituximab is an active, well-tolerated regimen for patients with previously treated chronic lymphocytic leukemia
-
Lamanna N., Kalaycio M., Maslak P., et al. Pentostatin, cyclophosphamide, and rituximab is an active, well-tolerated regimen for patients with previously treated chronic lymphocytic leukemia. J Clin Oncol 24 (2006) 1575-1581
-
(2006)
J Clin Oncol
, vol.24
, pp. 1575-1581
-
-
Lamanna, N.1
Kalaycio, M.2
Maslak, P.3
-
30
-
-
27244451794
-
Fludarabine in combination with alemtuzumab is effective and feasible in patients with relapsed or refractory B-cell chronic lymphocytic leukemia: results of a phase II trial
-
Elter T., Borchmann P., Schulz H., et al. Fludarabine in combination with alemtuzumab is effective and feasible in patients with relapsed or refractory B-cell chronic lymphocytic leukemia: results of a phase II trial. J Clin Oncol 23 (2005) 7024-7031
-
(2005)
J Clin Oncol
, vol.23
, pp. 7024-7031
-
-
Elter, T.1
Borchmann, P.2
Schulz, H.3
-
31
-
-
0038514130
-
Pentostatin and cyclophosphamide: an effective new regimen in previously treated patients with chronic lymphocytic leukemia
-
Weiss M.A., Maslak P.G., Jurcic J.G., et al. Pentostatin and cyclophosphamide: an effective new regimen in previously treated patients with chronic lymphocytic leukemia. J Clin Oncol 21 (2003) 1278-1284
-
(2003)
J Clin Oncol
, vol.21
, pp. 1278-1284
-
-
Weiss, M.A.1
Maslak, P.G.2
Jurcic, J.G.3
-
32
-
-
0037214931
-
Phase II study of cladribine and cyclophosphamide in patients with chronic lymphocytic leukemia and prolymphocytic leukemia
-
Montillo M., Tedeschi A., O'Brien S., et al. Phase II study of cladribine and cyclophosphamide in patients with chronic lymphocytic leukemia and prolymphocytic leukemia. Cancer 97 (2003) 114-120
-
(2003)
Cancer
, vol.97
, pp. 114-120
-
-
Montillo, M.1
Tedeschi, A.2
O'Brien, S.3
-
33
-
-
21144456107
-
Eradication of minimal residual disease in B-cell chronic lymphocytic leukemia after alemtuzumab therapy is associated with prolonged survival
-
Moreton P., Kennedy B., Lucas G., et al. Eradication of minimal residual disease in B-cell chronic lymphocytic leukemia after alemtuzumab therapy is associated with prolonged survival. J Clin Oncol 23 (2005) 2971-2979
-
(2005)
J Clin Oncol
, vol.23
, pp. 2971-2979
-
-
Moreton, P.1
Kennedy, B.2
Lucas, G.3
-
34
-
-
57449111685
-
Phase II study of subcutaneous alemtuzumab without dose escalation in patients with advanced-stage, relapsed chronic lymphocytic leukaemia
-
Karlsson C., Lundin J., Kimby E., et al. Phase II study of subcutaneous alemtuzumab without dose escalation in patients with advanced-stage, relapsed chronic lymphocytic leukaemia. Br J Haematol 144 (2009) 78-85
-
(2009)
Br J Haematol
, vol.144
, pp. 78-85
-
-
Karlsson, C.1
Lundin, J.2
Kimby, E.3
-
35
-
-
23044501404
-
Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia
-
Wierda W., O'Brien S., Wen S., et al. Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia. J Clin Oncol 23 (2005) 4070-4078
-
(2005)
J Clin Oncol
, vol.23
, pp. 4070-4078
-
-
Wierda, W.1
O'Brien, S.2
Wen, S.3
-
36
-
-
64749086917
-
Stem cell transplantation in chronic lymphocytic leukemia
-
Gribben J.G. Stem cell transplantation in chronic lymphocytic leukemia. Biol Blood Marrow Transplant 15 Suppl. 1 (2009) 53-58
-
(2009)
Biol Blood Marrow Transplant
, vol.15
, Issue.SUPPL. 1
, pp. 53-58
-
-
Gribben, J.G.1
-
37
-
-
33845543049
-
Indications for allogeneic stem cell transplantation in chronic lymphocytic leukemia: the EBMT transplant consensus
-
Dreger P., Corradini P., Kimby E., et al. Indications for allogeneic stem cell transplantation in chronic lymphocytic leukemia: the EBMT transplant consensus. Leukemia 21 (2007) 12-17
-
(2007)
Leukemia
, vol.21
, pp. 12-17
-
-
Dreger, P.1
Corradini, P.2
Kimby, E.3
-
38
-
-
20844436596
-
Reduced-intensity conditioning lowers treatment-related mortality of allogeneic stem cell transplantation for chronic lymphocytic leukemia: a population-matched analysis
-
Dreger P., Brand R., Milligan D., et al. Reduced-intensity conditioning lowers treatment-related mortality of allogeneic stem cell transplantation for chronic lymphocytic leukemia: a population-matched analysis. Leukemia 19 (2005) 1029-1033
-
(2005)
Leukemia
, vol.19
, pp. 1029-1033
-
-
Dreger, P.1
Brand, R.2
Milligan, D.3
-
39
-
-
38049141530
-
Outcomes after allogeneic hematopoietic cell transplantation with nonmyeloablative or myeloablative conditioning regimens for treatment of lymphoma and chronic lymphocytic leukemia
-
Sorror M.L., Storer B.E., Maloney D.G., Sandmaier B.M., Martin P.J., and Storb R. Outcomes after allogeneic hematopoietic cell transplantation with nonmyeloablative or myeloablative conditioning regimens for treatment of lymphoma and chronic lymphocytic leukemia. Blood 111 (2008) 446-452
-
(2008)
Blood
, vol.111
, pp. 446-452
-
-
Sorror, M.L.1
Storer, B.E.2
Maloney, D.G.3
Sandmaier, B.M.4
Martin, P.J.5
Storb, R.6
-
40
-
-
36348945154
-
Characterization of graft-versus-leukemia responses in patients treated for advanced chronic lymphocytic leukemia with donor lymphocyte infusions after in vitro T-cell depleted allogeneic stem cell transplantation following reduced-intensity conditioning
-
Hoogendoorn M., Jedema I., Barge R.M., et al. Characterization of graft-versus-leukemia responses in patients treated for advanced chronic lymphocytic leukemia with donor lymphocyte infusions after in vitro T-cell depleted allogeneic stem cell transplantation following reduced-intensity conditioning. Leukemia 21 (2007) 2569-2574
-
(2007)
Leukemia
, vol.21
, pp. 2569-2574
-
-
Hoogendoorn, M.1
Jedema, I.2
Barge, R.M.3
-
41
-
-
32644433461
-
Results of alemtuzumab-based reduced-intensity allogeneic transplantation for chronic lymphocytic leukemia: a British society of blood and marrow transplantation study
-
Delgado J., Thomson K., Russell N., et al. Results of alemtuzumab-based reduced-intensity allogeneic transplantation for chronic lymphocytic leukemia: a British society of blood and marrow transplantation study. Blood 107 (2006) 1724-1730
-
(2006)
Blood
, vol.107
, pp. 1724-1730
-
-
Delgado, J.1
Thomson, K.2
Russell, N.3
-
42
-
-
47549085972
-
Quantitative MRD monitoring identifies distinct GVL response patterns after allogeneic stem cell transplantation for chronic lymphocytic leukemia: results from the GCLLSG CLL3X trial
-
Ritgen M., Böttcher S., Stilgenbauer S., et al. Quantitative MRD monitoring identifies distinct GVL response patterns after allogeneic stem cell transplantation for chronic lymphocytic leukemia: results from the GCLLSG CLL3X trial. Leukemia 22 (2008) 1377-1386
-
(2008)
Leukemia
, vol.22
, pp. 1377-1386
-
-
Ritgen, M.1
Böttcher, S.2
Stilgenbauer, S.3
-
43
-
-
54449093967
-
Five-year follow-up of patients with advanced chronic lymphocytic leukemia treated with allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning
-
Sorror M.L., Storer B.E., Sandmaier B.M., et al. Five-year follow-up of patients with advanced chronic lymphocytic leukemia treated with allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning. J Clin Oncol 26 (2008) 4912-4920
-
(2008)
J Clin Oncol
, vol.26
, pp. 4912-4920
-
-
Sorror, M.L.1
Storer, B.E.2
Sandmaier, B.M.3
-
44
-
-
53749096361
-
The effect of in vivo T cell depletion with alemtuzumab on reduced-intensity allogeneic hematopoietic cell transplantation for chronic lymphocytic leukemia
-
Delgado J., Pillai S., Benjamin R., et al. The effect of in vivo T cell depletion with alemtuzumab on reduced-intensity allogeneic hematopoietic cell transplantation for chronic lymphocytic leukemia. Biol Blood Marrow Transplant 14 (2008) 1288-1297
-
(2008)
Biol Blood Marrow Transplant
, vol.14
, pp. 1288-1297
-
-
Delgado, J.1
Pillai, S.2
Benjamin, R.3
-
45
-
-
27744549869
-
Allogeneic transplant with reduced intensity conditioning regimens may overcome the poor prognosis of B-cell chronic lymphocytic leukaemia with unmutated immunoglobulin variable heavy-chain gene and chromosomal abnormalities (11q- and 17p-)
-
Caballero D., Garcia-Marco J.A., Martino R., et al. Allogeneic transplant with reduced intensity conditioning regimens may overcome the poor prognosis of B-cell chronic lymphocytic leukaemia with unmutated immunoglobulin variable heavy-chain gene and chromosomal abnormalities (11q- and 17p-). Clin Cancer Res 11 (2005) 7757-7763
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7757-7763
-
-
Caballero, D.1
Garcia-Marco, J.A.2
Martino, R.3
-
46
-
-
55549097826
-
Allogeneic hematopoietic stem-cell transplantation for chronic lymphocytic leukemia with 17p deletion: a retrospective European group for blood and marrow transplantation analysis
-
Schetelig J., van Biezen A., Brand R., et al. Allogeneic hematopoietic stem-cell transplantation for chronic lymphocytic leukemia with 17p deletion: a retrospective European group for blood and marrow transplantation analysis. J Clin Oncol 26 (2008) 5094-5100
-
(2008)
J Clin Oncol
, vol.26
, pp. 5094-5100
-
-
Schetelig, J.1
van Biezen, A.2
Brand, R.3
-
47
-
-
0026015638
-
Fludarabine: a new agent with marked cytoreductive activity in untreated chronic lymphocytic leukemia
-
Keating M.J., Kantarjian H., O'Brien S., et al. Fludarabine: a new agent with marked cytoreductive activity in untreated chronic lymphocytic leukemia. J Clin Oncol 9 (1991) 44-49
-
(1991)
J Clin Oncol
, vol.9
, pp. 44-49
-
-
Keating, M.J.1
Kantarjian, H.2
O'Brien, S.3
-
48
-
-
15844368449
-
Multicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia
-
Johnson S., Smith A.G., Loffler H., et al. Multicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia. Lancet 347 (1996) 1432-1438
-
(1996)
Lancet
, vol.347
, pp. 1432-1438
-
-
Johnson, S.1
Smith, A.G.2
Loffler, H.3
-
49
-
-
0036335916
-
Results of first salvage therapy for patients refractory to a fludarabine regimen in chronic lymphocytic leukemia
-
Keating M.J., O'Brien S.O., Kontoyiannis D., et al. Results of first salvage therapy for patients refractory to a fludarabine regimen in chronic lymphocytic leukemia. Leukemia Lymphoma 34 (2002) 1755-1762
-
(2002)
Leukemia Lymphoma
, vol.34
, pp. 1755-1762
-
-
Keating, M.J.1
O'Brien, S.O.2
Kontoyiannis, D.3
-
50
-
-
0036534380
-
Frequency and type of serious infections in fludarabine-refractory B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma. Implications for clinical trials in this patient population
-
Perkins J.G., Flynn J.M., Howard R.S., and Byrd J.C. Frequency and type of serious infections in fludarabine-refractory B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma. Implications for clinical trials in this patient population. Cancer 94 (2002) 2033-2039
-
(2002)
Cancer
, vol.94
, pp. 2033-2039
-
-
Perkins, J.G.1
Flynn, J.M.2
Howard, R.S.3
Byrd, J.C.4
-
51
-
-
0028987180
-
P53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias
-
Döhner H., Fischer K., Bentz M., et al. P53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias. Blood 85 (1995) 1580-1589
-
(1995)
Blood
, vol.85
, pp. 1580-1589
-
-
Döhner, H.1
Fischer, K.2
Bentz, M.3
-
52
-
-
60649093569
-
Rediscovering alemtuzumab: current and emerging therapeutic roles
-
Gribben J.G., and Hallek M. Rediscovering alemtuzumab: current and emerging therapeutic roles. Br J Haematol 144 (2009) 818-831
-
(2009)
Br J Haematol
, vol.144
, pp. 818-831
-
-
Gribben, J.G.1
Hallek, M.2
-
53
-
-
0037092951
-
Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: results of a large international study
-
Keating M.J., Flinn I., Jain V., et al. Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: results of a large international study. Blood 99 (2002) 3554-3561
-
(2002)
Blood
, vol.99
, pp. 3554-3561
-
-
Keating, M.J.1
Flinn, I.2
Jain, V.3
-
54
-
-
69849107362
-
Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: Clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group
-
doi:10.1200/JCO.2008.21.1128
-
Stilgenbauer S, Zenz T, Winkler D, et al. Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group. J Clin Oncol 2009;doi:10.1200/JCO.2008.21.1128.
-
(2009)
J Clin Oncol
-
-
Stilgenbauer, S.1
Zenz, T.2
Winkler, D.3
-
55
-
-
11144357657
-
Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions
-
Lozanski G., Heerema N.A., Flinn I.W., et al. Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions. Blood 103 (2004) 3278-3281
-
(2004)
Blood
, vol.103
, pp. 3278-3281
-
-
Lozanski, G.1
Heerema, N.A.2
Flinn, I.W.3
-
56
-
-
35148849255
-
The natural history of fludarabine-refractory chronic lymphocytic leukemia patients who fail alemtuzumab or have bulky lymphadenopathy
-
Tam C.S., O'Brien S., Lerner S., et al. The natural history of fludarabine-refractory chronic lymphocytic leukemia patients who fail alemtuzumab or have bulky lymphadenopathy. Leukemia Lymphoma 48 (2007) 1931-1939
-
(2007)
Leukemia Lymphoma
, vol.48
, pp. 1931-1939
-
-
Tam, C.S.1
O'Brien, S.2
Lerner, S.3
-
57
-
-
0035469851
-
Rituximab therapy of patients with B-cell chronic lymphocytic leukemia
-
Huhn D., von Schilling C., Wilhelm M., et al. Rituximab therapy of patients with B-cell chronic lymphocytic leukemia. Blood 98 (2001) 1326-1331
-
(2001)
Blood
, vol.98
, pp. 1326-1331
-
-
Huhn, D.1
von Schilling, C.2
Wilhelm, M.3
-
58
-
-
4444343395
-
Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas
-
Teeling J.L., French R.R., Cragg M.S., et al. Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas. Blood 104 (2004) 1793-1800
-
(2004)
Blood
, vol.104
, pp. 1793-1800
-
-
Teeling, J.L.1
French, R.R.2
Cragg, M.S.3
-
59
-
-
38949185742
-
Safety and efficacy of ofatumumab, a fully human monoclonal anti-CD20 antibody, in patients with relapsed or refractory B-cell chronic lymphocytic leukemia: a phase 1-2 study
-
Coiffier B., Lepretre S., Pedersen L.M., et al. Safety and efficacy of ofatumumab, a fully human monoclonal anti-CD20 antibody, in patients with relapsed or refractory B-cell chronic lymphocytic leukemia: a phase 1-2 study. Blood 111 (2008) 1094-1100
-
(2008)
Blood
, vol.111
, pp. 1094-1100
-
-
Coiffier, B.1
Lepretre, S.2
Pedersen, L.M.3
-
60
-
-
68349126054
-
-
Osterborg A, Kipps T, Mayer J et al. Ofatumumab (HuMax-CD20), a novel CD20 monoclonal antibody, is an active treatment for patients with CLL refractory to both fludarabine and alemtuzumab or bulky fludarabine-refractory disease: results from the planned interim analysis of an International Pivotal Trial [abstract]. Blood (ASH Annual Meeting Abstract) 2008;112: Abstract 328.
-
Osterborg A, Kipps T, Mayer J et al. Ofatumumab (HuMax-CD20), a novel CD20 monoclonal antibody, is an active treatment for patients with CLL refractory to both fludarabine and alemtuzumab or bulky fludarabine-refractory disease: results from the planned interim analysis of an International Pivotal Trial [abstract]. Blood (ASH Annual Meeting Abstract) 2008;112: Abstract 328.
-
-
-
-
61
-
-
68349134061
-
-
Fries T, Gerdes C, Nopora A et al. GA101, a novel humanized type II CD20 antibody with glycoengineered Fc and enhanced cell death induction, mediates superior efficacy in a variety of NHL xenograft models in comparison to rituximab [abstract]. Blood (ASH Annual Meeting Abstracts) 2007;110: Abstract 2338.
-
Fries T, Gerdes C, Nopora A et al. GA101, a novel humanized type II CD20 antibody with glycoengineered Fc and enhanced cell death induction, mediates superior efficacy in a variety of NHL xenograft models in comparison to rituximab [abstract]. Blood (ASH Annual Meeting Abstracts) 2007;110: Abstract 2338.
-
-
-
-
62
-
-
34547691135
-
Phase 1 study of lumiliximab with detailed pharmacokinetic and pharmacodynamic measurements in patients with relapsed or refractory chronic lymphocytic leukemia
-
Byrd J.C., O'Brien S., Flinn I.W., et al. Phase 1 study of lumiliximab with detailed pharmacokinetic and pharmacodynamic measurements in patients with relapsed or refractory chronic lymphocytic leukemia. Clin Cancer Res 13 (2007) 4448-4455
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4448-4455
-
-
Byrd, J.C.1
O'Brien, S.2
Flinn, I.W.3
-
63
-
-
68349153315
-
-
Byrd JC, Castro J, O'Brien S et al. Comparison of results from a phase 1/2 study of lumiliximab (anti-CD23) in combination with FCR for patients with relapsed CLL with published FCR results [abstract]. Blood (ASH Annual Meeting Abstracts) 2006;108: Abstract 32.
-
Byrd JC, Castro J, O'Brien S et al. Comparison of results from a phase 1/2 study of lumiliximab (anti-CD23) in combination with FCR for patients with relapsed CLL with published FCR results [abstract]. Blood (ASH Annual Meeting Abstracts) 2006;108: Abstract 32.
-
-
-
-
64
-
-
38349163290
-
Phase I-II study of oxaliplatin, fludarabine, cytarabine, and rituximab combination therapy in patients with Richter's syndrome or fludarabine-refractory chronic lymphocytic leukemia
-
Tsimberidou A.M., Wierda W.G., Plunkett W., et al. Phase I-II study of oxaliplatin, fludarabine, cytarabine, and rituximab combination therapy in patients with Richter's syndrome or fludarabine-refractory chronic lymphocytic leukemia. J Clin Oncol 26 (2008) 196-203
-
(2008)
J Clin Oncol
, vol.26
, pp. 196-203
-
-
Tsimberidou, A.M.1
Wierda, W.G.2
Plunkett, W.3
-
65
-
-
56249095457
-
Rituximab in combination with high-dose methylprednisolone for the treatment of fludarabine refractory high-risk chronic lymphocytic leukemia
-
Castro J.E., Sandoval-Sus J.D., Bole J., Rassenti L., and Kipps T.J. Rituximab in combination with high-dose methylprednisolone for the treatment of fludarabine refractory high-risk chronic lymphocytic leukemia. Leukemia 22 (2008) 2048-2053
-
(2008)
Leukemia
, vol.22
, pp. 2048-2053
-
-
Castro, J.E.1
Sandoval-Sus, J.D.2
Bole, J.3
Rassenti, L.4
Kipps, T.J.5
-
66
-
-
40849094878
-
High dose methylprednisolone and rituximab is an effective therapy in advanced refractory chronic lymphocytic leukemia resistant to fludarabine therapy
-
Dungarwalla M., Evans S.O., Riley U., Catovsky D., Dearden C.E., and Matutes E. High dose methylprednisolone and rituximab is an effective therapy in advanced refractory chronic lymphocytic leukemia resistant to fludarabine therapy. Haematologica 93 (2008) 475-476
-
(2008)
Haematologica
, vol.93
, pp. 475-476
-
-
Dungarwalla, M.1
Evans, S.O.2
Riley, U.3
Catovsky, D.4
Dearden, C.E.5
Matutes, E.6
-
67
-
-
68349126055
-
-
Wierda W, O'Brien S, Faderl S et al. Combined cyclophosphamide, fludarabine, alemtuzumab, and rituximab (CFAR), an active regimen for heavily treated patients with CLL [abstract]. Blood (ASH Annual Meeting Abstracts) 2006;108: Abstract 31.
-
Wierda W, O'Brien S, Faderl S et al. Combined cyclophosphamide, fludarabine, alemtuzumab, and rituximab (CFAR), an active regimen for heavily treated patients with CLL [abstract]. Blood (ASH Annual Meeting Abstracts) 2006;108: Abstract 31.
-
-
-
-
68
-
-
68349140275
-
-
Wierda W, O'Brien S, Faderl S et al. CFAR, an active frontline regimen for high-risk patients with CLL, including those with del17p [abstract]. Blood (ASH Annual Meeting Abstracts) 2008;112: Abstract 2095.
-
Wierda W, O'Brien S, Faderl S et al. CFAR, an active frontline regimen for high-risk patients with CLL, including those with del17p [abstract]. Blood (ASH Annual Meeting Abstracts) 2008;112: Abstract 2095.
-
-
-
-
69
-
-
68349145203
-
-
Fischer K, Stilgenbauer S, Schweighofer CD et al. Bendamustine in combination with rituximab for patients with relapsed chronic lymphocytic leukemia: a multicentre phase II trial of the German CLL Study Group [abstract]. Blood (ASH Annual Meeting Abstracts) 2008;112: Abstract 330.
-
Fischer K, Stilgenbauer S, Schweighofer CD et al. Bendamustine in combination with rituximab for patients with relapsed chronic lymphocytic leukemia: a multicentre phase II trial of the German CLL Study Group [abstract]. Blood (ASH Annual Meeting Abstracts) 2008;112: Abstract 330.
-
-
-
-
70
-
-
27744597929
-
Results of a phase I clinical trial of thalidomide in combination with fludarabine as initial therapy for patients with treatment-requiring chronic lymphocytic leukemia
-
Chanan-Khan A., Miller K.C., Takeshita K., et al. Results of a phase I clinical trial of thalidomide in combination with fludarabine as initial therapy for patients with treatment-requiring chronic lymphocytic leukemia. Blood 106 (2005) 3348-3352
-
(2005)
Blood
, vol.106
, pp. 3348-3352
-
-
Chanan-Khan, A.1
Miller, K.C.2
Takeshita, K.3
-
71
-
-
33947243663
-
Clinical efficacy of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia
-
Chanan-Khan A., Miller K.C., Musial L., et al. Clinical efficacy of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia. J Clin Oncol 24 (2006) 5343-5349
-
(2006)
J Clin Oncol
, vol.24
, pp. 5343-5349
-
-
Chanan-Khan, A.1
Miller, K.C.2
Musial, L.3
-
72
-
-
45149115902
-
Higher doses of lenalidomide are associated with unacceptable toxicity including life-threatening tumor flare in patients with chronic lymphocytic leukemia
-
Andritsos L.A., Johnson A.J., Lozanski G., et al. Higher doses of lenalidomide are associated with unacceptable toxicity including life-threatening tumor flare in patients with chronic lymphocytic leukemia. J Clin Oncol 26 (2008) 2519-2525
-
(2008)
J Clin Oncol
, vol.26
, pp. 2519-2525
-
-
Andritsos, L.A.1
Johnson, A.J.2
Lozanski, G.3
-
73
-
-
45949100928
-
Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia
-
Ferrajoli A., Lee B.N., Schlette E.J., et al. Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia. Blood 111 (2008) 5291-5297
-
(2008)
Blood
, vol.111
, pp. 5291-5297
-
-
Ferrajoli, A.1
Lee, B.N.2
Schlette, E.J.3
-
74
-
-
68349138434
-
-
Ferrajoli A, Keating M, Wierda W et al. Lenalidomide is active in patients with relapsed/refractory chronic lymphocytic leukemia carrying unfavorable chromosomal abnormalities [abstract]. Blood (ASH Annual Meeting Abstracts) 2007;110: Abstract 754.
-
Ferrajoli A, Keating M, Wierda W et al. Lenalidomide is active in patients with relapsed/refractory chronic lymphocytic leukemia carrying unfavorable chromosomal abnormalities [abstract]. Blood (ASH Annual Meeting Abstracts) 2007;110: Abstract 754.
-
-
-
-
75
-
-
68349158189
-
-
Chanan-Khan A, Czuczman M, Padmanabhan S et al. Clinical efficacy of lenalidomide in fludarabine-refractory chronic lymphocytic leukemia patients [abstract]. Blood (ASH Annual Meeting Abstracts) 2007;110: Abstract 3108.
-
Chanan-Khan A, Czuczman M, Padmanabhan S et al. Clinical efficacy of lenalidomide in fludarabine-refractory chronic lymphocytic leukemia patients [abstract]. Blood (ASH Annual Meeting Abstracts) 2007;110: Abstract 3108.
-
-
-
-
76
-
-
0032533599
-
Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53
-
Byrd J.C., Shinn C., Waselenko J.K., et al. Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53. Blood 92 (1998) 3804-3816
-
(1998)
Blood
, vol.92
, pp. 3804-3816
-
-
Byrd, J.C.1
Shinn, C.2
Waselenko, J.K.3
-
77
-
-
20344382459
-
Flavopiridol administered as a 24-h continuous infusion in chronic lymphocytic leukemia lacks clinical activity
-
Flinn I.W., Byrd J.C., Bartlett N., et al. Flavopiridol administered as a 24-h continuous infusion in chronic lymphocytic leukemia lacks clinical activity. Leukemia Res 29 (2005) 1253-1257
-
(2005)
Leukemia Res
, vol.29
, pp. 1253-1257
-
-
Flinn, I.W.1
Byrd, J.C.2
Bartlett, N.3
-
78
-
-
20344368831
-
Treatment of relapsed chronic lymphocytic leukemia by 72-h continuous infusion or 1-h bolus infusion of flavopiridol: results from cancer and leukemia group B study 19,805
-
Byrd J.C., Peterson B.L., Gabrilove J., et al. Treatment of relapsed chronic lymphocytic leukemia by 72-h continuous infusion or 1-h bolus infusion of flavopiridol: results from cancer and leukemia group B study 19,805. Clin Cancer Res 11 (2005) 4176-4181
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4176-4181
-
-
Byrd, J.C.1
Peterson, B.L.2
Gabrilove, J.3
-
79
-
-
33846219417
-
Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia
-
Byrd J.C., Lin T.S., Dalton J.T., et al. Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia. Blood 109 (2007) 399-404
-
(2007)
Blood
, vol.109
, pp. 399-404
-
-
Byrd, J.C.1
Lin, T.S.2
Dalton, J.T.3
-
80
-
-
63849246351
-
Clinical response and pharmacokinetics from a phase I study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia
-
Phelps M.A., Lin T.S., Johnson A.J., et al. Clinical response and pharmacokinetics from a phase I study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia. Blood 113 (2009) 2637-2645
-
(2009)
Blood
, vol.113
, pp. 2637-2645
-
-
Phelps, M.A.1
Lin, T.S.2
Johnson, A.J.3
-
81
-
-
66549124708
-
Mechanism of action of SNS-032, a novel cyclin dependent kinase inhibitor, in chronic lymphocytic leukemia
-
Chen R., Wierda W.G., Chubb S., et al. Mechanism of action of SNS-032, a novel cyclin dependent kinase inhibitor, in chronic lymphocytic leukemia. Blood 113 (2009) 4637-4645
-
(2009)
Blood
, vol.113
, pp. 4637-4645
-
-
Chen, R.1
Wierda, W.G.2
Chubb, S.3
-
82
-
-
55749105701
-
Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers
-
Pepper C., Lin T.T., Pratt G., et al. Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers. Blood 112 (2008) 3807-3817
-
(2008)
Blood
, vol.112
, pp. 3807-3817
-
-
Pepper, C.1
Lin, T.T.2
Pratt, G.3
-
83
-
-
33847328289
-
The Bcl-2 apoptotic switch in cancer development and therapy
-
Adams J.M., and Cory S. The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 26 (2007) 1324-1337
-
(2007)
Oncogene
, vol.26
, pp. 1324-1337
-
-
Adams, J.M.1
Cory, S.2
-
84
-
-
58849164097
-
Phase I study of obatoclax mesylate (GX15-070), a small molecule pan-Bcl-2 family antagonist, in patients with advanced chronic lymphocytic leukemia
-
O'Brien S.M., Claxton D.F., Crump M., et al. Phase I study of obatoclax mesylate (GX15-070), a small molecule pan-Bcl-2 family antagonist, in patients with advanced chronic lymphocytic leukemia. Blood 113 (2009) 299-305
-
(2009)
Blood
, vol.113
, pp. 299-305
-
-
O'Brien, S.M.1
Claxton, D.F.2
Crump, M.3
-
85
-
-
68349129141
-
-
Wilson WH, Czuczman MS, LaCasce AS et al. A phase 1 study evaluating the safety, pharmacokinetics, and efficacy of ABT-263 in subjects with refractory or relapsed lymphoid malignancies [abstract]. J Clin Oncol (ASCO Annual Meeting Abstracts) 2008;28: Abstract 8511.
-
Wilson WH, Czuczman MS, LaCasce AS et al. A phase 1 study evaluating the safety, pharmacokinetics, and efficacy of ABT-263 in subjects with refractory or relapsed lymphoid malignancies [abstract]. J Clin Oncol (ASCO Annual Meeting Abstracts) 2008;28: Abstract 8511.
-
-
-
-
86
-
-
68349129142
-
-
Roberts AW, Brown J, Seymour JF et al. An ongoing phase 1 study of ABT-263; pharmacokinetics, safety and anti-tumor activity in patients with relapsed or refractory chronic lymphocytic leukaemia [abstract]. Blood (ASH Annual Meeting Abstracts) 2008;112: Abstract 3177.
-
Roberts AW, Brown J, Seymour JF et al. An ongoing phase 1 study of ABT-263; pharmacokinetics, safety and anti-tumor activity in patients with relapsed or refractory chronic lymphocytic leukaemia [abstract]. Blood (ASH Annual Meeting Abstracts) 2008;112: Abstract 3177.
-
-
-
-
87
-
-
33645967205
-
Epigenetics in chronic lymphocytic leukemia
-
Raval A., Byrd J.C., and Plass C. Epigenetics in chronic lymphocytic leukemia. Semin Oncol 33 (2006) 157-166
-
(2006)
Semin Oncol
, vol.33
, pp. 157-166
-
-
Raval, A.1
Byrd, J.C.2
Plass, C.3
-
88
-
-
48849091231
-
Novel epigenetic targets in lymphoproliferative disorders
-
Delgado J. Novel epigenetic targets in lymphoproliferative disorders. Curr Cancer Drug Targets 8 (2008) 378-391
-
(2008)
Curr Cancer Drug Targets
, vol.8
, pp. 378-391
-
-
Delgado, J.1
-
89
-
-
19944432566
-
A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia
-
Byrd J.C., Marcucci G., Parthun M.R., et al. A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia. Blood 105 (2005) 959-967
-
(2005)
Blood
, vol.105
, pp. 959-967
-
-
Byrd, J.C.1
Marcucci, G.2
Parthun, M.R.3
-
90
-
-
42349095198
-
Downregulation of Mcl-1 potentiates HDACi-mediated apoptosis in leukemic cells
-
Inoue S., Walewska R., Dyer M.J., and Cohen G.M. Downregulation of Mcl-1 potentiates HDACi-mediated apoptosis in leukemic cells. Leukemia 22 (2008) 819-825
-
(2008)
Leukemia
, vol.22
, pp. 819-825
-
-
Inoue, S.1
Walewska, R.2
Dyer, M.J.3
Cohen, G.M.4
|