The expression of ENa+C and ASIC2 proteins in Pacinian corpuscles is differently regulated by TrkB and its ligands BDNF and NT-4

Neuroscience Letters

Volumn 463, Issue 2, 2009, Pages 114-118

  Montano J A ^a   Calavia, M G ^b   Garcia Suarez O ^b,c   Suarez Quintanilla, J A ^d   Galvez A ^b   Perez Pinera P ^b   Cobo, J ^e,f   Vega, J A ^b,g  

^a CATHOLIC UNIVERSITY OF MURCIA   (Spain)

^b Departamento de Morfologia y Biología Celular   (Spain)

^c ADITAS   (Spain)

^d UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^e Departamento de Cirugía y Especialidades Médico Quirúrgicas   (Spain)

^f Instituto Asturiano de Odontologia   (Spain)

^g UNIVERSITY OF OVIEDO   (Spain)

Author keywords

Acid sensing ion channel proteins; Epithelial Na+ channel proteins; Knock out mice; Neurotrophins; Pacinian corpuscles

Indexed keywords

ACID SENSING ION CHANNEL 2; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CATION CHANNEL; EPITHELIAL SODIUM CHANNEL; EPITHELIAL SODIUM CHANNEL ALPHA; EPITHELIAL SODIUM CHANNEL BETA; EPITHELIAL SODIUM CHANNEL GAMMA; NEUROTROPHIN 4; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOREACTIVITY; MECHANOTRANSDUCTION; MOUSE; NERVE FIBER; NONHUMAN; PACINI CORPUSCLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATORY MECHANISM;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; EPITHELIAL SODIUM CHANNEL; IMMUNOHISTOCHEMISTRY; LIGANDS; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; PACINIAN CORPUSCLES; PROTEIN SUBUNITS; RECEPTOR, TRKB; SODIUM CHANNELS;

EID: 68349128490     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.07.073     Document Type: Article

References (40)

1. Albuerne M., de Lavallina J., Esteban I., Naves F.J., Silos-Santiago I., and Vega J.A. Development of Meissner-like and Pacinian sensory corpuscles in the mouse demonstrated with specific markers for corpuscular constituents. Anat. Rec. 258 (2000) 235-242
2. Alvarez de la Rosa D., Zhang P., Shao D., White F., and Canessa C.M. Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous system. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 2326-2331
3. Belmonte C., and Viana F. Molecular and cellular limits to somatosensory specificity. Mol. Pain 4 (2008) 14 10.1186/1744-8069-4-14
4. de Carlos F., Cobo J., Germanà G., Silos-Santiago I., Laurà R., Haro J.J., Fariñas I., and Vega J.A. Abnormal development of Pacinian corpuscles in double trkB;trkC knockout mice. Neurosci. Lett. 410 (2006) 157-161
5. Drew L.J., Rohrer D.K., Price M.P., Blaver K.E., Cockayne D.A., Cesare P., and Wood J.N. Acid-sensing ion channels ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neurons. J. Physiol. 556 (2004) 691-710
6. Drummond H.A., Abboud F.M., and Welsh M.J. Localization of β and γ subunits of ENa+C in sensory nerve endings in the rat foot pad. Brain. Res. 884 (2000) 1-12
7. Drummond H.A., Furtado M.M., Myers S., Grifoni S., Parker K.A., Hoover A., and Stec D.E. ENa+C proteins are required for NGF-induced neurite growth. Am. J. Physiol. Cell Physiol. 290 (2006) C404-C410
8. Ernsberger U. Role of neurotrophin signalling in the differentiation of neurons from dorsal root ganglia and sympathetic ganglia. Cell Tissue Res. 336 (2009) 349-384
9. Ernstrom G.G., and Chalfie M. Genetics of sensory mechanotransduction. Annu. Rev. Genet. 36 (2002) 411-453
10. Fricke B., Lints R., Stewart G., Drummond H., Dodt G., Driscoll M., and von During M. Epithelial Na+ channels and stomatin are expressed in rat trigeminal mechanosensory neurons. Cell Tissue Res. 299 (2000) 327-334
11. Fundin B.T., Silos-Santiago I., Ernfors P., Fagan A.M., Aldskogius H., DeChiara T.M., Phillips H.S., Barbacid M., Yancopoulos G.D., and Rice F.L. Differential dependency of cutaneous mechanoreceptors on neurotrophins, trk receptors, and P75 LNGFR. Dev. Biol. 190 (1997) 94-116
12. Garcia-Añoveros J., Samad T.A., Zuvela-Jelaska L., Woolf C.J., and Corey D.P. Transport and localization of the DEG/ENa+C ion channel BNaC1α to peripheral mechanosensory terminals of dorsal root ganglia neurons. J. Neurosci. 21 (2001) 2678-2686
13. Gillespie P.G., and Walker R.G. Molecular basis of mechanosensory transduction. Nature 413 2001 (2001) 194-202
14. González-Martinez T., Fariñas I., del Valle M.E., Feito J., Germana G., Cobo J., and Vega J.A. BDNF, but not NT-4, is necessary for normal development of Meissner Pacinian corpuscles. Neurosci. Lett. 377 (2005) 12-15
15. Gonzalez-Martinez T., Germanà G.P., Monjil D.F., Silos-Santiago I., de Carlos F., Germanà G., Cobo J., and Vega J.A. Absence of Meissner corpuscles in the digital pads of mice lacking functional TrkB. Brain Res. 1002 (2004) 120-128
16. Hitomi Y., Suzuki A., Kawano Y., Nozawa-Inowe K., Inowe M., and Maeda T. Immunohistochemical detections of ENa+Cβ in the terminal Schwann cells associated with periodontal Ruffini endings of the rat incisor. Biomed. Res. 30 (2009) 113-119
17. Hughes P.A., Brierley S.M., Young R.L., and Blackshaw L.A. Localization and comparative analysis of acid-sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia. J. Comp. Neurol. 500 (2007) 863-875
18. Johnson K.O. The roles and functions of cutaneous mechanoreceptors. Curr. Opin. Neurobiol. 11 (2002) 455-461
19. Kawamata T., Ninomiya T., Toriyabe M., Yamamoto J., Niiyama Y., Omote K., and Namiki A. Immunohistochemical analysis of acid-sensing ion channel 2 expression in rat dorsal root ganglion and effects of axotomy. Neuroscience 143 (2006) 175-187
20. Krimm R.F., Davis B.M., Noel T., and Albers K.M. Overexpression of neurotrophin 4 in skin enhances myelinated sensory endings but does not influence sensory neuron number. J. Comp. Neurol. 498 (2006) 455-465
21. LeMaster A.M., Krimm R.F., Davis B.M., Noel T., Forbes M.E., Jonson J.E., and Albers K.M. Overexpression of brain-derived neurotrophic factor enhances sensory innervation and selectively increases neuron number. J. Neurosci. 19 (1999) 5919-5931
22. Lumpkin E.A., and Caterina M.J. Mechanisms of sensory transduction in the skin. Nature 445 (2007) 858-865
23. Mano I., and Driscoll M. DEG/ENa+C channels: a touchy superfamily that watches its salt. BioEssays 21 (1999) 568-578
24. McDonald F.J., Price M.P., Snyder P.M., and Welsh M.J. Cloning and expression of the beta- and gamma-subunits of the human epithelial sodium channel. Am. J. Physiol. 268 Pt 1 (1995) C1157-C1163
25. McIlwrath S.L., Hu J., Anirudhan G., Shin J.B., and Lewin G.R. The sensory mechanotransduction ion channel ASIC2 (acid-sensitive ion channel 2) is regulated by neurotrophin availability. Neuroscience 131 (2005) 499-511
26. McIlwrath S.L., Lawson J.J., Anderson C.E., Albers K.M., and Koerber H.R. Overexpression of neurotrophin-3 enhances the mechanical response properties of slowly adapting type 1 afferents and myelinated nociceptors. Eur. J. Neurosci. 26 (2007) 1801-1812
27. Munger B.L., and Ide C. The structure and function of cutaneous sensory receptors. Arch. Histol. Cytol. 51 (1988) 1-34
28. Pawson L., Slepecky N.B., and Bolanowski S.J. Immunocytochemical identification of proteins within the Pacinian corpuscle. Somatosens. Mot. Res. 17 (2000) 159-170
29. Pawson L., Checkosky C.M., Pack A.K., and Bolanowski S.J. Mesenteric and tactile Pacinian corpuscles are anatomically and physiologically comparable. Somatosens. Mot. Res. 25 (2008) 194-206
30. Perez-Piñera P., García-Suarez O., Germanà A., Díaz-Esnal B., de Carlos F., Silos-Santiago I., del Valle M.E., Cobo J., and Vega J.A. Characterization of sensory deficits in TrkB knockout mice. Neurosci. Lett. 433 (2008) 43-47
31. Perl E.R. Function dorsal root ganglion neurons: an overview. In: Scott S.A. (Ed). Sensory Neurons: Diversity, Development and Plasticity (1992), Oxford University Press, New York 3-23
32. Price M.P., McIlwrath S.L., Xie J., Cheng C., Qiao J., Tarr D.E., Sluka K.A., Brennan T.J., Lewin G.R., and Welsh M.J. The DRASIC cation channel contributes to the detection of cutaneous touch and acid stimuli in mice. Neuron 32 (2001) 1071-1083
33. Price M.P., Lewin G.R., McIlwrath S.L., Cheng C., Xie J., Heppenstall P.A., Stucky C.L., Mannsfeldt A.G., Brennan T.J., Drummond H.A., Qiao J., Benson C.J., Tarr D.E., Hrstka R.F., Yang B., Williamson R.A., and Welsh M.J. The mammalian sodium channel BNC1 is required for normal touch sensation. Nature 407 (2000) 1007-1011
34. Rice F.L., Albers K.M., Davis B.M., Silos-Santiago I., Wilkinson G.A., LeMaster A.M., Ernfors P., Smeyne R.J., Aldskogius H., Phillips H.S., Barbacid M., DeChiara T.M., Yancopoulos G.D., Dunne C.E., and Fundin B.T. Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR. Dev. Biol. 198 (1998) 57-81
35. Sedý J., Szeder V., Walro J.M., Ren Z.G., Nanka O., Tessarollo L., Sieber-Blum M., Grim M., and Kucera J. Pacinian corpuscles development involves multiple Trk signalling pathways. Dev. Dyn. 231 (2004) 551-563
36. Stark B., Risling M., and Carlstedt T. Distribution of the neurotrophin receptors p75 and trkB in peripheral mechanoreceptors; observations on changes after injury. Exp. Brain Res. 136 (2001) 101-107
37. Vega J.A., Haro J.J., and Del Valle M.E. Immunohistochemistry of human cutaneous Meissner and Pacinian corpuscles. Microsc. Res. Tech. 34 (1996) 351-361
38. Vega J.A., García-Suárez O., Montaño J.A., Pardo B., and Cobo J.M. The Meissner and Pacinian sensory corpuscles revisited new data from the last decade. Microsc. Res. Tech. 72 (2009) 299-309
39. Waldmann R., Champigny G., Bassilana F., Heurteaux C., and Lazdunski M. A proton-gated cation channel involved in acid-sensing. Nature 386 (1997) 173-177
40. Zelena J. Nerves and Mechanoreceptors (1994), Chapman & Hall, London