Recent advancements and applications in the analysis of traditional Chinese medicines

Planta Medica

Volumn 75, Issue 7, 2009, Pages 776-783

  Ganzera, Markus ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Analysis; Quality control; TCM; Traditional Chinese medicine

Indexed keywords

ANGELICA SINENSIS EXTRACT; COUMARIN DERIVATIVE; FLAVONOID; GINSENOSIDE; HONOKIOL; LIGUSTICUM CHUANXIONG EXTRACT; MAGNOLOL; PEONOL; SAFFLOWER EXTRACT; HERBACEOUS AGENT;

ANGELICA SINENSIS; CAPILLARY ELECTROCHROMATOGRAPHY; CHINESE MEDICINE; COUNTER CURRENT CHROMATOGRAPHY; DRUG ANALYSIS; DRUG SYNTHESIS; FOOD AND DRUG ADMINISTRATION; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROSCOPY; PRINCIPAL COMPONENT ANALYSIS; SHORT SURVEY; CHEMISTRY; METHODOLOGY; REVIEW; STANDARD;

CHEMISTRY, ANALYTICAL; DRUGS, CHINESE HERBAL;

EID: 68349120530     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1185686     Document Type: Short Survey

References (72)

1. Xinhua W, Changguo W, Xiaoyun M. Basic theory of traditional Chinese medicine, 1st edition. Shanghai: Publishing House of Shanghai University of Traditional Chinese Medicine; 2002: 1-10
2. Bensky D, Clavey S, Stöger E. Chinese herbal medicine - materia medica, 3rd edition. Seattle: Eastland Press; 2004: 13-31
3. Hempen CH, Fischer T. Leitfaden Chinesische Phytotherapie, 2nd edition. München: Urban & Fischer; 2007: 2-19
4. Li SL, Lin G, Fu PP, Chan CL, Li M, Jiang ZH, Zhao ZZ. Identification of five hepatotoxic pyrrolizidine alkaloids in a commonly used traditional Chinese medicinal herb, Herba Senecionis scandentis (Qianliguang). Rapid Commun Mass Spectrom 2008; 22: 591-602
5. Wu KM, Farrelly JG, Upton R, Chen J. Complexities of herbal nomenclature system in traditional Chinese medicine (TCM): lessons learned from the misuse of Aristolochia-related species and the importance of the pharmaceutical name during botanical drug product development. Phytomedicine 2007; 14: 273-279 (Pubitemid 46386394)
6. Li W, Chen Z, Liao Y, Liu H. Separation methods for toxic components in traditional Chinese medicines. Anal Sci 2005; 21: 1019-1029 (Pubitemid 41554034)
7. Liu S, Yi LZ, Liang, YZ. Traditional Chinese medicine and separation science. J Sep Sci 2008; 31: 2113-2137 (Pubitemid 352003191)
8. Liu Z. Preparation of botanical samples for biomedical research. Endocrine Metab Immune Disord Drug Targ 2008; 8: 112-121
9. Deng C, Liu N, Gao M, Zhang X. Recent developments in sample preparation techniques for chromatography analysis of traditional Chinese medicines. J Chromatogr A 2007; 1153: 90-96 (Pubitemid 46778852)
10. Li Y, Wang Y, Qu H, Cheng Y. Simultaneous determination of seven bioactive compounds in Chinese medicine Qi-Shen-Yi-Qi dropping pill by LC-UV and LC-ELSD. Chromatographia 2008; 67: 293-297
11. Su J, Fu P, Shen Y, Zhang C, Liang M, Lui R, Li H, Zhang W. Simultaneous analysis of flavonoids from Hypericum japonicum Thunb. ex Murray (Hypericaceae) by HPLC-DAD-ESI/MS. J Pharm Biomed Anal 2008; 46: 342-348
12. Zheng X, Shi P, Cheng Y, Qu H. Rapid analysis of a Chinese herbal prescription by liquid chromatography-time-of-flight tandem mass spectrometry. J Chromatogr A 2008; 1206: 140-146
13. Chan EC, Yap SL, Lau AJ, Leow PC, Toh TF, Koh HL. Ultra-performance liquid chromatography/time-of-flight mass spectrometry based metabolomics of raw and steamed Panax notoginseng. Rapid Commun Mass Spectrom 2008; 21: 519-528
14. Dan M, Su M, Gao X, Zhao T, Zhao A, Xie G, Qiu Y, Zhou M, Liu Z, Jia W. Metobolite profiling of Panax notoginseng using UPLC-ESI-MS. Phytochemistry 2008; 69: 2237-2244
15. Xie G, Plumb R, Su M, Xu Z, Zhao A, Qiu M, Long X, Liu Z, Jia W. Ultraperformance LC/TOF MS analysis of medicinal Panax herbs for metabolomic research. J Sep Sci 2008; 31: 1015-1026 (Pubitemid 351649827)
16. Chen XJ, Ji H, Zhang QW, Tu PF, Wang YT, Guo BL, Li SP. A rapid method for simultaneous determination of 15 flavonoids in Epimedium using pressurized liquid extraction and ultra-performance liquid chromatography. J Pharm Biomed Anal 2008; 46: 226-235
17. Jin Y, Zhang X, Shi H, Xiao YS, Ke YX, Xue YX, Zhang FF, Liang XM. Characterisation of C-glycosyl quinochalcones in Carthamus tinctorius L. by ultra-performance liquid chromatography coupled with quadrupoletime- of-flight mass spectrometry. Rapid Commun Mass Spectrom 2008; 22: 1275-1287 (Pubitemid 351600778)
18. Maruyama T, Kamakura H, Miyai M, Komatsu K, Kawasaki T, Fujita M, Shimada H, Yamamoto Y, Shibata T, Goda Y. Authentication of traditional medicinal plant Eleutherococcus senticosus by DNA and chemical analysis. Planta Med 2008; 74: 787-789 (Pubitemid 351881005)
19. Hemström P, Irgum K. Hydrophilic interaction chromatography. J Sep Sci 2006; 29: 1784-1821
20. Wang Y, Lu X, Xu G. Simultaneous separation of hydrophilic and hydrophobic compounds using an online HILIC-RPLC system with two detectors. J Sep Sci 2008; 31: 1564-1572 (Pubitemid 351890783)
21. Davis JM, Giddings JC. Statistical theory of component overlap in multicomponent chromatograms. Anal Chem 1983; 55: 418-424
22. Hu L, Chen X, Kong L, Su X, Ye M, Zou H. Improved performance of comprehensive two-dimensional HPLC separation of traditional Chinese medicines using a silica monolithic column and normalization of peak heights. J Chromatogr A 2005; 1092: 191-198 (Pubitemid 41393927)
23. Liu Y, Xue X, Guo Z, Xu Q, Zhang F, Liang X. Novel two-dimensional liquid chromatography/hydrophilic interaction chromatography, an excellent orthogonal system for practical analysis. J Chromatogr A 2008; 1208: 133-140
24. Ma S, Chen L, Luo G, Ren K, Wu J, Wang Y. Off-line comprehensive twodimensional high-performance liquid chromatography system with size exclusion column and reverse phase column for separation of complex traditional Chinese medicine Qingkailing injection. J Chromatogr A 2006; 1127: 207-213 (Pubitemid 44278840)
25. Deng C, Ji J, Wang X, Zhang X. Development of pressurized hot water extraction followed by headspace solid-phase microextraction and gas chromatography-mass spectrometry for determination of ligustilides in Ligusticum chuanxiong and Angelica sinensis. J Sep Sci 2005; 28: 1237-1243 (Pubitemid 41057269)
26. Shen S, Sha Y, Deng C, Zhang X, Fu C, Chen J. Quality assessment of Flos Chrysanthemi indici from different growing areas in China by solidphase microextraction-gas chromatography-mass spectrometry. J Chromatogr A 2004; 1047: 281-287 (Pubitemid 39164701)
27. Dong L, Wang J, Deng C, Shen X. Gas chromatography-mass spectrometry following pressurized hot water extraction and solid-phase microextraction for quantification of eucalyptol, camphor, and borneol in Chrysanthemum flowers. J Sep Sci 2007; 30: 80-89 (Pubitemid 46157538)
28. Li N, Mao Y, Deng C, Zhang X. Separation and identification of volatile constituents in Artemisia argyi flowers by GC-MS with SPME and steam distillation. J Chromatogr Sci 2008; 46: 401-405 (Pubitemid 351669002)
29. Deng C, Yao N, Wang B, Zhang X. Development of microwave assisted extraction followed by headspace dingle-droplet microextraction for fast determination of paeonol in traditional Chinese medicines. J Chromatogr A 2006; 1103: 15-21 (Pubitemid 43038622)
30. Dong L, Deng C, Wang B, Shen X. Fast determination of Z-ligustilide in plasma by gas-chromatography/mass spectrometry following headspace single-droplet extraction. J Sep Sci 2007; 30: 1318-1325 (Pubitemid 46979330)
31. Ito J, Bowman RL. Countercurrent chromatography: liquid-liquid chromatography without solid support. Science 1970; 167: 281-283
32. Ito Y. Golden rules and pitfalls in selecting optimum conditions for high-speed counter-current chromatography. J Chromatogr A 2005; 1065: 145-168 (Pubitemid 40228728)
33. Wang X, Liu J, Thang T, Ito Y. Rapid and simple method for quality control of raw materials of herbs by HSCCC. J Liquid Chromatogr Res Technol 2007; 30: 2585-2592 (Pubitemid 47256074)
34. Ganzera M. Quality control of herbal medicines by capillary electrophoresis: potential, requirements and applications. Electrophoresis 2008; 29: 3489-3503
35. Chen Y, Fan G, Chen B, Xie Y, Wu H, Wu Y, Yan C, Wang Y. Separation and quantitative analysis of coumarin compounds from Angelica dahurica (Fisch. ExHoffm.) Benth. et Hook. f. by pressurized capillary electrochromatography. J Pharm Biomed Anal 2006; 41: 105-116
36. Yang F, Li S, Li P, Wang Y. Optimization of CEC for simultaneous determination of eleven nucleosides and nucleobases in Cordyceps using central composite design. Electrophoresis 2007; 28: 1681-1688 (Pubitemid 46909723)
37. Chen X, Ji H, Wang Y, Li S. Simultaneous determination of seven flavonoids inEpimedium using pressurized liquid extraction and capillary electrochromatography. J Sep Sci 2008; 31: 881-887
38. Eeltink S, Svec F. Recent advances in the control of morphology and surface chemistry of porous polymer-based monolithic stationary phases and their application in CEC. Electrophoresis 2007; 28: 131-147 (Pubitemid 46178956)
39. Lü H, Wang J, Wang X, Lin X, Wu X, Xie Z. Rapid separation and determination of structurally related anthraquinones in rhubarb by pressurized liquid chromatography. J Pharm Biomed Anal 2007; 43: 352-357 (Pubitemid 44856198)
40. Zhang L, Zhang J, Wang H, Zhang L, Zhang W, Zhang Y. Analysis of leaves of Adinandra nitida by capillary electrochromatography on monolithic columns with stepwise gradient elution. J Sep Sci 2005; 28: 774-779 (Pubitemid 40852123)
41. Dong J, Ou J, Dong X, Wu R, Ye M, Zou H. Preparation and evaluation of rigid porous polyacrylamide-based strong cation-exchange monolithic columns for capillary electrochromatography. J Sep Sci 2007; 30: 2986-2992 (Pubitemid 350238332)
42. Lin X, Wang J, Li L, Wang X, Lü H, Xie Z. Separation and determination of five major opium alkaloids with mixed mode of hydrophilic/cationic exchange monolith by pressurized capillary electrochromatography. J Sep Sci 2007; 30: 3011-3017 (Pubitemid 350238335)
43. Huang H, Yu H, Xu H, Ying Y. Near infrared spectroscopy for on/in-line monitoring of quality in foods and beverages: a review. J Food Eng 2008; 87: 303-313
44. Wu YW, Sun SQ, Zhou Q, Leung HW. Fourier transform mid-infrared (MIR) and near-infrared (NIR) spectroscopy for the rapid quality assessment of Chinese medicine preparation Honghua oil. J Pharm Biomed Anal 2008; 46: 498-504
45. Huang RJ, Zhuang ZX, Tai Y, Huang RF, Wang XR, Lee F. Direct analysis of mercury in traditional Chinese medicines using thermolysis coupled with on-line atomic absorption spectrometry. Talanta 2006; 68: 728-734 (Pubitemid 43052479)
46. Jia Y, Tan X, Li Q, Cheng W, Chen X, Bi K. Quality control of TCMs using a chromatographic fingerprint. Asian J Trad Med 2006; 1: 94-100
47. Liang YZ, Xie P, Chan K. Quality control of herbal medicines. J Chromatogr B 2004; 812: 53-70
48. n. J Pharm Biomed Anal 2008; 47: 778-785
49. Liu H, Sun S, Lv G, Liang X. Discrimination of extracted lipophilic constituents of Angelica with multi-steps infrared macro-fingerprint method. Vib Spec 2006; 40: 202-208
50. Ni Y, Peng Y, Kokot S. Fingerprinting of complex mixtures with the use of high performance liquid chromatography, inductively coupled plasma atomic absorptionemission spectroscopy and chemometrics. Anal Chim Acta 2008; 616: 19-27
51. Li Y, Hu Z, He L. An approach to develop binary chromatographic fingerprints of the total alkaloids from Caulophyllum robustum by high performance liquid chromatography/diode array detector and gas chromatography/ mass spectrometry. J Pharm Biomed Anal 2007; 43: 1667-1672 (Pubitemid 46453083)
52. Chen J, Wang F, Liu J, Lee F, Wang X, Yang H. Analysis in Coptis chinensis Franch by accelerated solvent extraction combined with ultra performance liquid chromatographic analysis with photodiode array and tandem mass spectrometry detections. Anal Chim Acta 2008; 613: 184-195
53. Pei LK, Sun SQ, Guo BL, Huang WH, Xiao PG. Fast quality control of Herba Epimedii by using Fourier transform infrared spectroscopy. Spectrochim Acta A 2008; 70: 258-264
54. Chen Y, Yan Y, Xie MY, Nie SP, Liu W, Gong XF, Wang YX. Development of a chromatographic fingerprint for the chloroform extracts of Ganoderma lucidum by HPLC and LC-MS. J Pharm Biomed Anal 2008; 47: 469-477
55. Sun G, Liu J. Qualitative and quantitative assessment of the HPLC fingerprints of Ginkgo biloba extract by the involution similarity method. Anal Sci 2007; 23: 955-958
56. Xie G, Zhao A, Li P, Li L, Jia W. Fingerprint analysis of Rhizoma chuanxiong by pressurized capillary electrochromatography and high performance liquid chromatography. Biomed Chromatogr 2007; 21: 867-875 (Pubitemid 47215147)
57. ChangWT, Thissen U, Ehlert KA, Koek M, Jellema R, Hakemeier T, van der Greef J, Wang M. Effects of growth conditions and processing on Rehmannia glutinosa using fingerprint strategy. Planta Med 2006; 72: 458-467
58. Gu M, Zhang S, Su Z, Chen Y, Ouyang F. Fingerprinting of Salvia miltiorrhiza Bunge by non-aqueous capillary electrophoresis compared with high-speed counter-current chromatography. J Chromatogr A 2004; 1057: 133-140 (Pubitemid 39463076)
59. Gu M, Su Z, Ouyang F. Fingerprinting of Salvia miltiorrhiza Bunge by thin-layer chromatography scan compared with high-speed countercurrent chromatography. J Liquid Chromatogr Res Technol 2006; 29: 1503-1514
60. Liang M, Zhang J, Liu R, Yan S, Zhang W, Lin M. Chemical profile of Danning tablets by LC-DAD coupled with ESI-MS. Chromatographia 2007; 66: 107-110 (Pubitemid 47030164)
61. Wang Y, Kong L, Hu L, Lei X, Yang L, Chou G, Zuo H, Wang C, Bligh SWA, Wang Z. Biological fingerprinting analysis of the traditional Chinese prescription Longdan Xiegan decoction by on/off-line comprehensive two-dimensional biochromatography. J Chromatogr B 2007; 860: 185-194 (Pubitemid 350181633)
62. Krishnan P, Kruger NJ, Ratcliffe RG. Metabolite fingerprinting and profiling in plants using NMR. J Exp Bot 2005; 56: 255-265 (Pubitemid 40191443)
63. Holmes E, Tang H, Wang Y, Seger C. The assessment of plant metabolite profiles by NMR-based methodologies. Planta Med 2006; 72: 771-785 (Pubitemid 44204639)
64. Seger C, Sturm S. Analytical aspects of plant metabolite profiling platforms: current standings and future aims. J Proteome Res 2007; 6: 480-497 (Pubitemid 46340152)
65. 1H-NMR spectroscopy and principal components analysis. Arch Pharm Res 2007; 30: 1625-1628
66. Tarachiwin L, Katoh A, Ute K, Fukusaki E. Quality evaluation of Angelica acutiloba Kitagawa roots by 1H NMR-based metabolic fingerprinting. J Pharm Biomed Anal 2008; 48: 42-48
67. Kim HK, Choi YH, Erkelens C, Lefeber A, Verpoorte R. Metabolic fingerprinting of Ephedra species using 1H-NMR spectroscopy and principal component analysis. Chem Pharm Bull 2005; 53: 105-109 (Pubitemid 40879848)
68. Ma C, Wang H, Lu X, Xu G, Liu B. Metabolic fingerprinting investigation of Artemisia annua L. in different stages of development by gas chromatography and gas chromatography-mass spectrometry. J Chromatogr A 2008; 1186: 412-419
69. Morinaga O, Zhu S, Tanaka H, Shoyama Y. Visual detection of saikosaponins by on-membrane immunoassay and estimation of traditional Chinese medicines containing Bupleuri Radix. Biochem Biophys Res Commun 2006; 346: 687-692 (Pubitemid 43949254)
70. Xu J, Tanaka H, ShoyanaY. One-step immunochromatographic separation and ELISA quantification of glycyrrhizin from traditional Chinese medicines. J Chromatogr B 2007; 850: 53-58 (Pubitemid 46618142)
71. Rong J, Tilton R, Shen J, Ng KM, Liu C, Tam P, Lau ASY, Cheng YC. Genomewide biological response fingerprinting (BioReF) of the Chinese botanical formulation ISF-1 enables the selection ofmultiple marker genes as a potential metric for quality control. J Ethnopharmacol 2007; 113: 35-44 (Pubitemid 47082498)
72. Guideline on the quality of herbal medicinal products. Available at http://www.emea.europa.eu/pdfs/human/qwp/281900en.pdf. Accessed March 10, 2009