Synthesis of N,O-homonucleosides with high conformational freedom

Arkivoc

Volumn 2009, Issue 8, 2009, Pages 168-176

  Romeo, Giovanni ^a   Giofré, Salvatore V ^a   Piperno, Anna ^a   Romeo, Roberto ^a   Chiacchiob, Maria Assunta ^b  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF CATANIA   (Italy)

Author keywords

1,3 Dipolar cycloaddition; Antiviral agents; Homonucleosides; Nitrones; Vinyloxymethyl thymine

Indexed keywords

EID: 68349105868     PISSN: 1551-7012     EISSN: 15517012     Source Type: Journal    
DOI: 10.3998/ark.5550190.0010.814     Document Type: Article

References (19)

1. Ohrui, H. Nucleic Acid Symposium, 2008, Series No.52, pp 631-632.
2. Herdewijn, P., Modified Nucleosides in Biochemistry, Biothecnology and Medicine; Ed. Wiley-VCH: Weinhein, 2008.
3. Jordeheim, L. P.; Galmarini, C. M.; Dumontet, C. Recent Pat. Anti-Cancer Drug Discovery 2006, 1, 163.
4. Schinazi, R. F.; Hernadez-Santiago, B. I.; Hurvitz, S. J. Antiviral Res. 2006, 71, 322.
5. Piperno, A.; Chiacchio, U.; Iannazzo, D.; Romeo, R. Curr. Med. Chem. 2006, 13, 3467.
6. Chiacchio, U.; Genovese, F.; Librando, V.; Iannazzo, D.; Merino, P.; Rescifina, A.; Romeo, R.; Procopio, A.; Romeo, G., Tetrahedron 2004, 60, 441.
7. Chiacchio, U.; Saita, M. G.; Crispino, L.; Gumina, G.; Mangiafico, S.; Pistara, V.; Romeo, G.; Piperno, A.; De Clercq, E. Tetrahedron 2006, 62, 1171.
8. Hossain, N.; Blaton, N.; Peeters, O.; Rozenski, J.; Herdewijin, P.A., Tetrahedron, 1996, 52, 5563.
9. Lamberth, C. Org. Prep. Proc. Int. 2002, 34, 149.
10. De Clercq, E. J. Med. Chem. 2005, 48, 1.
11. Boal, J. H.; Scremin, C. L.; Gray, G. N.; Phillips, L. R.; Beaucage, S. L. J. Org. Chem. 1996, 61, 8617.
12. Doi, Y.; Chiba, J.; Morikawa, T.; Inouye, M. J. Am. Chem. Soc. 2008, 130, 8762 and references therein.
13. Kim, C. U.; Misco, P. F.; Luh, B. Y.; Hitchcock, M. J. M.; Ghazzuoli, I.; Martin, J. C. J. Med. Chem. 1991, 34, 2286.
14. Rollin, P.; Verez Bencomo, V.; Sinay, P. Synthesis 1983, 134.
15. Reich, H. J.; Wollowitz, S.; Trend, J. E.; Chow, F.; Wendelborn, D. F., J. Org. Chem. 1978, 43, 1697.
16. Annunziata, R.; Benaglia, M.; Cinquini, M.; Cozzi, F.; Raimondi, L. Eur. J. Org. Chem. 1998, 1823.
17. Merino, P.; Revuelta, J.; Tejero, T.; Chiacchio, U.; Rescifina, A.; Romeo, G., Tetrahedron 2003, 59, 3581.
18. Balestrieri, E.; Matteucci, C.; Ascolani, A.; Piperno, A.; Romeo, R.; Romeo, G.; Chiacchio, U.; Mastino, A.; Macchi, B. Antimicrobial Agents and Chemotherapy 2008, 52, 54.
19. Chiacchio, U.; Rescifina, A.; Iannazzo, D.; Piperno, A.; Romeo, R.; Borrello, L.; Sciotino, M.T.; Balestrieri, E .; Macchi, B.; Mastino, A.; Romeo, G. J. Med. Chem. 2007, 50, 3747.