Response surface methodology for optimization of medium components in submerged culture of Aspergillus flavus for enhanced heparinase production

Letters in Applied Microbiology

Volumn 49, Issue 2, 2009, Pages 204-209

  Banga, J ^a   Tripathi, C K M ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Aspergillus flavus; Central composite design; Heparinase; Response surface methodology

Indexed keywords

CALCIUM CHLORIDE; CHITIN; DESIGN; DRUG PRODUCTS PLANTS; FERMENTATION; POLYSACCHARIDES; SURFACE PROPERTIES;

ANTITHROMBOTIC; ASPERGILLUS FLAVUS; CENTRAL COMPOSITE DESIGN; CENTRAL COMPOSITE DESIGNS; FERMENTATION MEDIUM; HEPARINASE; LOW-MOLECULAR WEIGHT HEPARINS; MEDIUM COMPONENTS; MEDIUM OPTIMIZATION; NITROGEN SOURCES; PHARMACEUTICAL INDUSTRY; PLACKETT-BURMAN DESIGNS; RESPONSE SURFACE METHODOLOGY; SALT SOLUTION; STATISTICAL APPROACH; STATISTICAL DESIGN; STATISTICAL MODELS; STATISTICAL OPTIMIZATION; SUBMERGED CULTURES;

OPTIMIZATION;

AMMONIUM NITRATE; CALCIUM CHLORIDE; CHITIN; COBALT CHLORIDE; COPPER SULFATE; DIPOTASSIUM HYDROGEN PHOSPHATE; FERROUS SULFATE; HEPARIN; HEPARIN LYASE; MAGNESIUM SULFATE; MANNITOL; MOLYBDATE SODIUM; SODIUM DIHYDROGEN PHOSPHATE;

COMPOSITE; ENZYME ACTIVITY; FUNGUS; METHODOLOGY; MODELING; OPTIMIZATION;

ARTICLE; ASPERGILLUS FLAVUS; ENZYME SYNTHESIS; FERMENTATION MEDIUM; FUNGAL STRAIN; FUNGUS CULTURE; FUNGUS ISOLATION; NONHUMAN;

ASPERGILLUS FLAVUS;

EID: 68249141236     PISSN: 02668254     EISSN: 1472765X     Source Type: Journal    
DOI: 10.1111/j.1472-765X.2009.02640.x     Document Type: Article

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