Calpain inhibition induces activation of the distinct signalling pathways and cell migration in human monocytes

Immunology

Volumn 128, Issue 1 PART 2, 2009, Pages

  Noma, Haruyoshi ^a   Kato, Takayuki ^a   Fujita, Hisakazu ^a   Kitagawa, Maki ^a   Yamano, Tsunekazu ^a   Kitagawa, Seiichi ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Mitogen activated protein kinases; Pertussis toxin; Phosphatidylinositol 3 kinase; Rac

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CALPAIN; CYSTEINE PROTEINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; N ACETYLLEUCYLLEUCYLNORLEUCINAL; P21 ACTIVATED KINASE; PD 145305; PD 150606; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ADULT; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOREGULATION; LEUKOCYTE ACTIVATION; LEUKOCYTE MIGRATION; MONOCYTE; NORMAL HUMAN; PHAGOCYTE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ACRYLATES; AMINOQUINOLINES; CALPAIN; CHEMOTAXIS; HUMANS; LYMPHOCYTES; MONOCYTES; NEUTROPHILS; PERTUSSIS TOXIN; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PYRIMIDINES; RAC GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 68249135245     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2008.03012.x     Document Type: Article

References (26)

1. Franco SJ, Huttenlocher A. Regulating cell migration: calpains make the cut. J Cell Sci 2005 118 : 3829 38.
2. Wells A, Huttenlocher A, Lauffenburger DA. Calpain proteases in cell adhesion and motility. Int Rev Cytol 2005 245 : 1 16.
3. Dourdin N, Bhatt AK, Dutt P, Greer PA, Arthur JS, Elce JS, Huttenlocher A. Reduced cell migration and disruption of the actin cytoskeleton in calpain-deficient embryonic fibroblasts. J Biol Chem 2001 276 : 48382 8.
4. Lokuta MA, Nuzzi PA, Huttenlocher A. Calpain regulates neutrophil chemotaxis. Proc Natl Acad Sci USA 2003 100 : 4006 11.
5. Knepper-Nicolai B, Savill J, Brown SB. Constitutive apoptosis in human neutrophils requires synergy between calpains and the proteasome downstream of caspases. J Biol Chem 1998 273 : 30530 6.
6. Kobayashi S, Yamashita K, Takeoka T et al. Calpain-mediated X-linked inhibitor of apoptosis degradation in neutrophil apoptosis and its impairment in chronic neutrophilic leukemia. J Biol Chem 2002 277 : 33968 77.
7. Nuzzi PA, Senetar MA, Huttenlocher A. Asymmetric localization of calpain 2 during neutrophil chemotaxis. Mol Biol Cell 2007 18 : 795 805.
8. Katsube M, Kato T, Kitagawa M, Noma H, Fujita H, Kitagawa S. Calpain-mediated regulation of the distinct signaling pathways and cell migration in human neutrophils. J Leukoc Biol 2008 84 : 255 63.
9. Suzuki K, Hino M, Hato F, Tatsumi N, Kitagawa S. Cytokine-specific activation of distinct mitogen-activated protein kinase subtype cascades in human neutrophils stimulated by granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, and tumor necrosis factor-α. Blood 1999 93 : 341 9.
10. Yuo A, Kitagawa S, Motoyoshi K, Azuma E, Saito M, Takaku F. Rapid priming of human monocytes by human hematopoietic growth factors: granulocyte- macrophage colony-stimulating factor (CSF), macrophage-CSF, and interleukin-3 selectively enhance superoxide release triggered by receptor-mediated agonists. Blood 1992 79 : 1553 7.
11. Nakamae-Akahori M, Kato T, Masuda S et al. Enhanced neutrophil motility by granulocyte colony-stimulating factor: the role of extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. Immunology 2006 119 : 393 403.
12. Aomatsu K, Kato T, Fujita H et al. Toll-like receptor agonists stimulate human neutrophil migration via activation of mitogen-activated protein kinases. Immunology 2008 123 : 171 80.
13. Rosser BG, Powers SP, Gores GJ. Calpain activity increases in hepatocytes following addition of ATP. Demonstration by a novel fluorescent approach. J Biol Chem 1993 268 : 23593 600.
14. Bokoch GM. Biology of the p21-activated kinases. Annu Rev Biochem 2003 72 : 743 81.
15. Yen H, Zhang Y, Penfold S, Rollins BJ. MCP-1-mediated chemotaxis requires activation of non-overlapping signal transduction pathways. J Leukoc Biol 1997 61 : 529 32.
16. Cambien B, Pomeranz M, Millet MA, Rossi B, Schmid-Alliana A. Signal transduction involved in MCP-1-mediated monocytic transendothelial migration. Blood 2001 97 : 359 66.
17. Kintscher U, Wakino S, Kim S, Fleck E, Hsueh WA, Law RE. Angiotensin II induces migration and Pyk2/paxillin phosphorylation of human monocytes. Hypertension 2001 37 : 587 93.
18. McGilvray ID, Tsai V, Marshall JC, Dackiw AP, Rotstein OD. Monocyte adhesion and transmigration induce tissue factor expression: role of the mitogen-activated protein kinases. Shock 2002 18 : 51 7.
19. Fine JS, Byrnes HD, Zavodny PJ, Hipkin RW. Evaluation of signal transduction pathways in chemoattractant-induced human monocyte chemotaxis. Inflammation 2001 25 : 61 7.
20. Kulkarni S, Saido TC, Suzuki K, Fox JE. Calpain mediates integrin-induced signaling at a point upstream of Rho family members. J Biol Chem 1999 274 : 21265 75.
21. Li Z, Hannigan M, Mo Z et al. Directional sensing requires Gββ-mediated PAK1 and PIXα-dependent activation of Cdc42. Cell 2003 114 : 215 27.
22. Beeser A, Jaffer ZM, Hofmann C, Chernoff J. Role of group A p21-activated kinases in activation of extracellular-regulated kinase by growth factors. J Biol Chem 2005 280 : 36609 15.
23. Lee SH, Eom M, Lee SJ, Kim S, Park HJ, Park D. βPix-enhanced p38 activation by Cdc42/Rac/PAK/MKK3/6-mediated pathway. Implication in the regulation of membrane ruffling. J Biol Chem 2001 276 : 25066 72.
24. Coso OA, Chiariello M, Yu JC, Teramoto H, Crespo P, Xu N, Miki T, Gutkind JS. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 1995 81 : 1137 46.
25. Ozaki Y, Kato T, Kitagawa M, Fujita H, Kitagawa S. Calpain inhibition delays neutrophil apoptosis via cyclic AMP-independent activation of protein kinase A and protein kinase A-mediated stabilization of Mcl-1 and X-linked inhibitor of apoptosis (XIAP). Arch Biochem Biophys 2008 477 : 227 31.
26. Nishiki S, Hato F, Kamata N, Sakamoto E, Hasegawa T, Kimura-Eto A, Hino M, Kitagawa S. Selective activation of STAT3 in human monocytes stimulated by G-CSF: implication in inhibition of LPS-induced TNF-α production. Am J Physiol Cell Physiol 2004 286 : C1302 11.