Effect of oral administration of dried royal sun agaricus, agaricus brasiliensis S. Wasser et al. (Agaricomycetideae), fruit bodies on anti-β-glucan antibody titers in humans

International Journal of Medicinal Mushrooms

Volumn 11, Issue 2, 2009, Pages 117-131

  Ishibashi, Ken Ichi ^a   Motoi, Masuro ^a,b   Liu, Ying ^c   Miura, Noriko N ^a   Adachi, Yoshiyuki ^a   Ohno, Naohito ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b Toei Pharmaceutical Co Ltd   (Japan)

^c Mibyou Medical Research Center   (Japan)

Author keywords

? glucan; Agaricus brasiliensis; Anti ? glucan antibody; Medicinal mushrooms; Oral administration; Royal Sun Agaricus

Indexed keywords

AGARICUS BLAZEI EXTRACT; ANTIBODY; BETA GLUCAN; BETA GLUCAN ANTIBODY; PLACEBO; UNCLASSIFIED DRUG;

ADULT; ANTIBODY PRODUCTION; ANTIBODY TITER; ANTIGEN ANTIBODY REACTION; ARTICLE; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MUSHROOM BODY; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL;

AGARICUS; AGARICUS BLAZEI; AGARICUS BRASILIENSIS; BASIDIOMYCOTA;

EID: 68249114029     PISSN: 15219437     EISSN: None     Source Type: Journal    
DOI: 10.1615/IntJMedMushr.v11.i2.20     Document Type: Article

References (41)

1. Rios-Hernandez M, Dos-Santos NJ, Silvia-Cardoso, Bello-Garciga JL, Pedroso M. Immunopharmacological studies of beta-1,3-glucan. Arch Med Res. 1994;25: 179-80.
2. Stone BB, Clarke AE. Chemistry and biology of (1→3)-β-glucans. Australia: La Trobe University Press; 1992.
3. Van den Eynde BJ, van der Bruggen P. T cell defined tumor antigens. Curr Opin Immunol. 1997;9:684-93.
4. Taguchi T. Lentinan. Gan To Kagaku Ryoho. 1986;13: 3294-304.
5. Fujimoto S, Furue H, Kimura T, Kondo T, Orita K, Ta-guchi T, Yoshida K, Ogawa N. Clinical outcome of postoperative adjuvant immunochemotherapy with sizofiran for patients with resectable gastric cancer: a randomized controlled study. Eur J Cancer. 1991;27:1114-8.
6. Ohno N, Furukawa M, Miura NN, Adachi Y, Motoi M, Yadomae T. Antitumor beta glucan from the cultured fruit body of Agaricus blazei. Biol Pharm Bull. 2001;24:820-8.
7. Kasai H, He LM, Kawamura M, Yang PT, Deng XW, Munkanta M, Yamashita A, Terunuma H, Hirama M, Horiuchi I, Natori T, Koga T, Amano Y, Yamaguchi N, Ito M. IL-12 production induced by Agaricus blazei fraction H involves Toll-like receptor. Evid Based Complement Alternat Med. 2004;1:259-67.
8. Shu CH, Wen BJ, Lin KJ. Monitoring the polysaccha-ride quality of Agaricus blazei in submerged culture by examining molecular weight distribution and TNF-alpha release capability of macrophage cell line RAW 264.7. Biotechnol Lett. 2004;26:2061-4.
9. Liu Y, Fukuwatari Y, Okumura K, Takeda K, Ishibashi K, Frukawa M, Ohno N, Mori K, Gao M, Motoi M. Immunomodulating activity of Agaricus brasiliensis KA21 in mice and in human volunteers. Evid Based Complement Alternat Med. 2008;5:205-19.
10. Iino K, Ohno N, Suzuki I, Sato K, Oikawa S, Yadomae T. Structure-function relationship of antitumor beta-1,3-glucan obtained from matted mycelium of cultured Grifola frondosa. Chem Pharm Bull. 1985;33: 4950-6.
11. Ohno N, Suzuki I, Oikawa S, Sato K, Miyazaki T, Yado-mae T. Antitumor activity and structural characterization of glucans extracted from cultured fruit bodies of Grifola frondosa. Chem Pharm Bull. 1984;32:1142-51.
12. Ohno N, Iino K, Takeyama T, Suzuki I, Sato K, Oikawa S, Miyazaki T, Yadomae T. Structural characterization and antitumor activity of the extracts from matted mycelium of cultured Grifola frondosa. Chem Pharm Bull. 1985;33:2564-8.
13. Ohno N, Suzuki I, Yadomae T. Structure and antitumor activity of a beta-1,3-glucan isolated from the culture filtrate of Sclerotinia sclerotiorum IFO 9395. Chem Pharm Bull. 1986;34:1362-5.
14. Shinohara H, Ohno N, Yadomae T. Antitumor activity and structural characterization of a (1-3)-beta-D-glucan extracted with cold alkali from sclerotia of Sclerotinia sclerotiorum IFO 9395. Chem Pharm Bull. 1988;36:819-23.
15. Saito K, Nishijima M, Ohno N, Yadomae T, Miyazaki T. Structure and antitumor activity of the less-branched derivatives of an alkali-soluble glucan isolated from Omphalia lapidescens. (Studies on fungal polysaccharide. XXXVIII). Chem Pharm Bull. 1992;40:261-3.
16. Mimura H, Ohno N, Suzuki I, Yadomae T. Purification, antitumor activity, and structural characterization of beta-1,3-glucan from Peziza vesiculosa. Chem Pharm Bull. 1985;33:5096-9.
17. Ohno N, Uchiyama M, Tsuzuki A, Tokunaka K, Miura NN, Adachi Y, Aizawa MW, Tamura H, Tanaka S, Yadomae T. Solubilization of yeast cell-wall beta-(1→3)-D-glucan by sodium hypochlorite oxidation and dimethyl sulfoxide extraction. Carbohydr Res. 1999;316:161-72.
18. Ishibashi K, Miura NN, Adachi Y, Tamura H, Tanaka S, Ohno N. The solubilization and biological activities of Aspergillus beta-(1→3)-D- glucan. FEMS Immunol Med Microbiol. 2004;42:155-66.
19. Ohno N, Miura T, Miura NN, Chiba N, Uchiyama M, Adachi Y, Yadomae T. Infl ammatory and immuno-pharmacological activities of meta-periodate oxidized zymosan. Zentralbl Bakteriol. 1999;289:63-77.
20. Ohno N, Miura T, Miura NN, Adachi Y, Yadomae T. Structure and biological activities of hypochlorite oxidized zymosan. Carbohydr Polym. 2001;44:339-49.
21. Ohno N, Miura NN, Nakajima M, Yadomae T. Antitumor 1,3-beta-glucan from cultured fruit body of Sparassis crispa. Biol Pharm Bull. 2000;23:866-72.
22. Yadomae T, Ohno N. Structure-activity relationship of immunomodulating (1→3)-β-D-glucans. Recent Res Dev Chem Pharm Sci. 1996;1:23-33.
23. Yadomae T. Structure and biological activities of fungal beta-1,3-glucans. Yakugaku Zasshi. 2000;120:413-31.
24. Brown GD, Gordon S. Immune recognition. A new receptor for beta-glucans. Nature. 2001;413:36-7.
25. Ross GD, Cain JA, Myones BL, Newman SL, Lachmann PJ. Specificity of membrane complement receptor type three for beta-glucans. Complement. 1987;4:61-74.
26. Zimmerman JW, Lindermuth J, Fish PA, Palace GP, Stevenson TT, DeMong DE. A novel carbohydrate-glycosphingolipid interaction between a beta-(1-3)-glucan immunomodulator, PGG-glucan, and lactosyl-ceramide of human leukocytes. J Biol Chem. 1998;273: 22014-20.
27. Uchiyama M, Ohno N, Miura NN, Adachi Y, Tamura H, Tanaka S, Yadomae T. Solubilized cell wall beta-glucan, CSBG, is an epitope of Candida immune mice. Biol Pharm Bull. 2000;23:672-6.
28. Masuzawa S, Yoshida M, Ishibsahi K, Saito N, Akashi M, Yshikawa N, Suzuki T, Nameda S, Miura NN, Adachi Y, Ohno N. Solubilized Candida cell wall β-glucan, CSBG, is epitope of natural human antibody. Drug Dev Res. 2003;58:179-89.
29. Chiani P, Bromuro C, Cassone A, Torosantucci A. Anti-beta-glucan antibodies in healthy human subjects. Vaccine. 2009;27:513-9.
30. Motoi M, Ishibashi K, Mizukami O, Miura NN, Adachi Y, Ohno N. Anti β-glucan antibody in cancer patients. Int J Med Mushr. 2004;6:41-8.
31. Harada T, Miura NN, Adachi Y, Nakajima M, Yadomae T, Ohno N. Antibody to soluble 1,3/1,6-beta-D-glucan, SCG in sera of naive DBA/2 mice. Biol Pharm Bull. 2003;26:1225-8.
32. Ishibashi K, Dogasaki C, Iriki T, Motoi M, Kurone Y, Miura NN, Adachi Y, Ohno N. Anti-β-glucan antibody in bovine sera. Int J Med Mushr. 2005;7:533-45.
33. Ishibashi K, Yoshida M, Nakabayashi I, Shinohara H, Miura NN, Adachi Y, Ohno N. Role of anti-beta-glucan antibody in host defense against fungi. FEMS Immunol Med Microbiol. 2005;44:99-109.
34. Torosantucci A, Bromuro C, Chiani P, De Bernardis F, Berti F, Galli C, Norelli F, Bellucci C, Polonelli L, Costantino P, Rappuoli R, Cassone A. A novel glyco-conjugate vaccine against fungal pathogens. J Exp Med. 2005;202:597-606.
35. Rachini A, Pietrella D, Lupo P, Torosantucci A, Chiani P, Bromuro C, Proietti C, Bistoni F, Cassone A. Vecchiarelli A. An anti-beta-glucan monoclonal antibody inhibits growth and capsule formation of Cryptococcus neofor-mans in vitro and exerts therapeutic, anticryptococcal activity in vivo. Infect Immun. 2007;75:5085-94.
36. Kondori N, Edebo L, Mattsby-Baltzer I. A novel monoclonal antibody recognizing beta(1-3) glucans in intact cells of Candida and Cryptococcus. APMIS. 2008;116:867-76.
37. Suzuki I, Hashimoto K, Ohno N, Tanaka H, Yadomae T. Immunomodulation by orally administered beta-glucan in mice. Int J Immunopharmacol. 1989;11:761-9.
38. Suzuki I, Tanaka H, Kinoshita A, Oikawa S, Osawa M, Yadomae T. Effect of orally administered beta-glucan on macrophage function in mice. Int J Immunopharmacol. 1990;12:675-84.
39. Suzuki I, Sakurai T, Hashimoto K, Oikawa S, Masuda A, Ohsawa M, Yadomae T. Inhibition of experimental pulmonary metastasis of Lewis lung carcinoma by orally administered beta-glucan in mice. Chem Pharm Bull. 1991;39:1606-8.
40. Rice PJ, Adams EL, Ozment-Skelton T, Gonzalez AJ, Goldman MP, Lockhart BE, Barker LA, Breuel KF, Deponti WK, Kalbfleisch JH, Ensley HE, Brown GD, Gordon S, Williams DL. Oral delivery and gastrointestinal absorption of soluble glucans stimulate increased resistance to infectious challenge. J Pharmacol Exp Ther. 2005;314:1079-86.
41. Sakamaki S, Kohgo Y, Suzuki M, Ogiwara R, Suga T, Kondo N, Izawa M, Kanisawa Y, Niitsu Y. Individual diversity of IL-6 generation by human monocytes with lentinan administration. Int J Immunopharmacol. 1993;15:751-6.