Melatonin deficiency and disrupted circadian rhythms in pediatric survivors of craniopharyngioma

Neurology

Volumn 73, Issue 4, 2009, Pages 323-325

  Lipton, J ^a   Megerian, J T ^a   Kothare, S V ^a   Cho, Y J ^a   Shanahan, T ^c   Chart, H ^a   Ferber, R ^a   Adler Golden, L ^a   Cohen, L E ^b   Czeisler, C A ^c   Pomeroy, S L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MELATONIN;

ACTIMETRY; ADOLESCENT; ADULT; ARTICLE; CASE REPORT; CIRCADIAN RHYTHM; CRANIOPHARYNGIOMA; FEMALE; HORMONE DEFICIENCY; HUMAN; HYPOPITUITARISM; MALE; MELATONIN DEFICIENCY; MORBID OBESITY; POLYSOMNOGRAPHY; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; SEIZURE; SLEEP APNEA SYNDROME; SLEEP WAKING CYCLE; SOMNOLENCE;

EID: 68249113185     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3181af78a5     Document Type: Article

References (7)

1. Prabhu VC, Brown HG. The pathogenesis of craniopharyngiomas. Childs Nerv Syst 2005;21:622- 627.
2. Palm L, Nordin V, Elmqvist D, Blennow G, Persson E, Westgren U. Sleep and wakefulness after treatment for craniopharyngioma in childhood; influence on the quality and maturation of sleep. Neuropediatrics 1992;23:39-45.
3. van der Klaauw AA, Biermasz NR, Pereira AM, et al. Patients cured from craniopharyngioma or non-functioning pituitary macroadenoma suffer similarly from increased daytime somnolence despite normal sleep patterns compared to healthy controls. Clin Endocrinol (Oxf) 2008;69:769-774.
4. Muller HL, Handwerker G, Wollny B, Faldum A, Sorensen N. Melatonin secretion and increased daytime sleepiness in childhood craniopharyngioma patients. J Clin Endocrinol Metab 2002;87:3993-3996.
5. Bojkowski CJ, Arendt J, Shih MC, Markey SP. Melatonin secretion in humans assessed by measuring its metabolite, 6-sulfatoxymelatonin. Clin Chem 1987;33:1343-1348.
6. Arendt J. Melatonin: characteristics, concerns, and prospects. J Biol Rhythms 2005;20:291-303.
7. Muller HL, Handwerker G, Gebhardt U, et al. Melatonin treatment in obese patients with childhood craniopharyngioma and increased daytime sleepiness. Cancer Causes Control 2006;17:583-589.