Geranylated flavonoids from the roots of campylotropis hirtella and their immunosuppressive activities

Journal of Agricultural and Food Chemistry

Volumn 57, Issue 15, 2009, Pages 6712-6719

  Shou, Qing Yao ^a   Run Zhong, F U ^b   Qing, T A N ^a   Shen, Zheng W U ^a,c  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Ln Wan Senior High School   (China)

^c Basilea Pharmaceutical China Ltd   (China)

Author keywords

Campylotropis hirtella; Geranylated flavonoids; Immunosuppressants; Leguminosaea

Indexed keywords

FLAVONOID; HERBACEOUS AGENT; IMMUNOSUPPRESSIVE AGENT;

ANIMAL; ARTICLE; B LYMPHOCYTE; BAGG ALBINO MOUSE; CELL CULTURE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; CYTOTOXICITY TEST; DRUG EFFECT; IMMUNOLOGY; LEGUME; MOUSE; PLANT ROOT; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE;

ANIMALS; B-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; CYTOTOXICITY TESTS, IMMUNOLOGIC; DRUGS, CHINESE HERBAL; FABACEAE; FLAVONOIDS; IMMUNOSUPPRESSIVE AGENTS; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; PLANT ROOTS; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES;

CAMPYLOTROPIS; HIRTELLA;

EID: 68249093118     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf9009894     Document Type: Article

References (14)

1. Toungouz, M.; Donckier, V.; Goldman, M. Tolerance induction in clinical transplantation: The pending questions. Transplantation 2003, 75 (Suppl. 9), 58S-60S.
2. Offermann, G. Immunosuppression for long-term maintenance of renal allograft function. Drugs 2004, 64, 1325-1338.
3. Ramgolam, V.; Aug, S. G.; Lan, Y. H.; Loh, C. S.; Yah, H. K. Traditional Chinese medicines as immunosuppressive agents, Ann. Acad. Med. Singapore 2000, 29, 11-16.
4. Chen, B. J. Triptolide. a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium Wilfordii Hook. f. Leuk. Lymphoma 2001, 42, 253-265.
5. Qiu, D. M. Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Triptervgium Wilfordii Hook. f. Drugs R&D 2003, 4, 1-18.
6. Lu, H.; Hanchida. M.; Enosawa, S.; Li, X. K.; Suzuki, S.; Koyangagi, H. Immunosuppressive effect of triptolide. Transplant. Proc. 1999, 31, 2056-2057.
7. Pharmacopoeia Committee of the People's Republic of China Edita Chinese material medica. In Pharmacopoeia of the People's Republic of China; People's Hygiene Press: Beijing, 1977; pp 30-31.
8. Asai, T.; Hara, N.; Kobayashi, S.; Kohshima, S.; Fujimoto, Y. Geranylated flavanones from the secretion on the surface of the immature fruits of Paulownia tomentosa, Phytochemistry 2008, 69, 1234-1241.
9. Miyase, T.; Sano, M.; Yoshino, K.; Nonaka, K. Antioxidants from Lespedeza homoloha. Phytochemistry 1999, 52, 311-319.
10. Iwata, N.; Wang, N. L.; Yao, X. S.; Kitanaka, S. Structures and histamine release inhibitory effects of prenylated orcinol derivatives from Rhododendron dauricum. J. Nat. Prod. 2004, 67, 1106-1109.
11. Benavides, A.; Bassarello, C.; Montoro, P.; Vilegas. W.; Piacente, S.; Pizza, C. Flavonoids and isoflavonoids from Gynerium sagittatum. Phytochemistry 2007, 68, 1277-1284.
12. Islam, M. T.; Tahara, S. Dihydroflavonols from Lanneu eoromundelica. Phytochemistry 2000, 54, 901-907.
13. Kang, L.; Zhou, J. X.; Shen, Z. W. Two novel antibacterial flavonoids from Myrsine africana L. Chin. J. Chem. 2007, 25, 1323-1325.
14. Komatsu, M.; Yokoe. I.; Shirataki. Y. Studies on the constituents of Sophora species. Constituents of the parts of Sophora tomentosa L. (2). Chem. Pharm. Bull. 1978, 26, 3863-3870.