The human leukocyte antigen class II gene has different contributions to autoimmune Type 1 diabetes with or without autoimmune thyroid disease in the Japanese population

Diabetes Research and Clinical Practice

Volumn 85, Issue 3, 2009, Pages 293-297

  Katahira, Masahito ^a   Maeda, Harumi ^a   Tosaki, Takahiro ^a   Segawa, Satoko ^a  

^a Ichinomiya Municipal Hospital   (Japan)

Author keywords

Autoimmune thyroid disease (AITD); Autoimmune Type 1 (type 1A) diabetes; Graves' disease; Hashimoto's thyroiditis; Human leukocyte antigen (HLA)

Indexed keywords

HLA ANTIGEN CLASS 2; HLA DQB1 ANTIGEN; HLA DR ANTIGEN; INSULIN;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOIMMUNE DISEASE; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; FEMALE; GENE FREQUENCY; GENETIC SUSCEPTIBILITY; HAPLOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; JAPANESE; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; THYROID DISEASE;

ADOLESCENT; ADULT; AGE OF ONSET; AGED; AGED, 80 AND OVER; CHILD; DIABETES MELLITUS, TYPE 1; FEMALE; GENES, MHC CLASS II; GRAVES DISEASE; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HUMANS; JAPAN; MALE; MIDDLE AGED; THYROIDITIS, AUTOIMMUNE; YOUNG ADULT;

EID: 68249092355     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2009.06.007     Document Type: Article

References (22)

1. Barker J.M. Clinical review: Type 1 diabetes-associated autoimmunity: natural history, genetic associations, and screening. J. Clin. Endocrinol. Metab. 91 (2006) 1210-1217
2. Golden B., Levin L., Ban Y., Concepcion E., Greenberg D.A., and Tomer Y. Genetic analysis of families with autoimmune diabetes and thyroiditis: evidence for common and unique genes. J. Clin. Endocrinol. Metab. 90 (2005) 4904-4911
3. Awata T., and Kanazawa Y. Genetic markers for insulin-dependent diabetes mellitus in Japanese. Diabetes Res. Clin. Pract. 24 Suppl. (1994) S83-S87
4. Hashimoto K., Maruyama H., Nishiyama M., Asaba K., Ikeda Y., Takao T., et al. Susceptibility alleles and haplotypes of human leukocyte antigen DRB1, DQA1, and DQB1 in autoimmune polyglandular syndrome type III in Japanese population. Horm. Res. 64 (2005) 253-260
5. Ikegami H., Awata T., Kawasaki E., Kobayashi T., Maruyama T., Nakanishi K., et al. The association of CTLA4 polymorphism with type 1 diabetes is concentrated in patients complicated with autoimmune thyroid disease: a multicenter collaborative study in Japan. J. Clin. Endocrinol. Metab. 91 (2006) 1087-1092
6. Chikuba N., Akazawa S., Yamaguchi Y., Kawasaki E., Takino H., Takao Y., et al. Type 1 (insulin-dependent) diabetes mellitus with coexisting autoimmune thyroid disease in Japan. Intern. Med. 31 (1992) 1076-1080
7. Alberti K.G., and Zimmet P.Z. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet. Med. 15 (1998) 539-553
8. Imagawa A., Hanafusa T., Uchigata Y., Kanatsuka A., Kawasaki E., Kobayashi T., et al. Fulminant type 1 diabetes: a nationwide survey in Japan. Diabetes Care 26 (2003) 2345-2352
9. Nakajima F., Nakamura J., and Yokota T. Analysis of HLA haplotypes in Japanese, using high resolution allele typing. J. Jpn. Soc. Histocompat. Immunogen. 8 (2001) 1-32
10. Katahira M., Ishiguro T., Segawa S., Kuzuya-Nagao K., Hara I., and Nishisaki T. Reevaluation of human leukocyte antigen DR-DQ haplotype and genotype in type 1 diabetes in the Japanese population. Horm. Res. 69 (2008) 284-289
11. Urcelay E., Santiago J.L., de la Calle H., Martínez A., Méndez J., Ibarra J.M., et al. Type 1 diabetes in the Spanish population: additional factors to class II HLA-DR3 and -DR4. BMC Genomics 20 (2005) 56
12. Undlien D.E., Kockum I., Rønningen K.S., Lowe R., Saanjeevi C.B., Graham J., et al. HLA associations in type 1 diabetes among patients not carrying high-risk DR3-DQ2 or DR4-DQ8 haplotypes. Tissue Antigens 54 (1999) 543-551
13. Graham J., Kockum I., Sanjeevi C.B., Landin-Olsson M., Nyström L., Sundkvist G., et al. Swedish Childhood Diabetes Study Group, Negative association between type 1 diabetes and HLA DQB1*0602-DQA1*0102 is attenuated with age at onset. Eur. J. Immunogenet. 26 (1999) 117-127
14. Zeitlin A.A., Heward J.M., Newby P.R., Carr-Smith J.D., Franklyn J.A., Gough S.C., et al. Analysis of HLA class II genes in Hashimoto's thyroiditis reveals differences compared to Graves' disease. Genes Immun. 9 (2008) 358-363
15. Park M.H., Park Y.J., Song E.Y., Park H., Kim T.Y., Park D.J., et al. Association of HLA-DR and -DQ genes with Graves disease in Koreans. Hum. Immunol. 66 (2005) 741-747
16. Tamai H., Kimura A., Dong R.P., Matsubayashi S., Kuma K., Nagataki S., et al. Resistance to autoimmune thyroid disease is associated with HLA-DQ. J. Clin. Endocrinol. Metab. 78 (1994) 94-97
17. Azuma Y., Sakurami T., Ueno Y., Ohishi M., Saji H., Terasaki P.I., et al. HLA-DR antigens in Japanese with Hashimoto's thyroiditis and Graves' disease. Endocrinol. Jpn. 29 (1982) 423-427
18. Honda K., Tamai H., Morita T., Kuma K., Nishimura Y., and Sasazuki T. Hashimoto's thyroiditis and HLA in Japanese. J. Clin. Endocrinol. Metab. 69 (1989) 1268-1273
19. Iwama S., Ikezaki A., Kikuoka N., Kim H.S., Matsuoka H., Yanagawa T., et al. Association of HLA-DR,-DQ genotype and CTLA-4 gene polymorphism with Graves' disease in Japanese children. Horm. Res. 63 (2005) 55-60
20. Takeda H., Kawasaki E., Shimizu I., Konoue E., Fujiyama M., Murao S., et al. Clinical, autoimmune, and genetic characteristics of adult-onset diabetic patients with GAD autoantibodies in Japan (Ehime Study). Diabetes Care 25 (2002) 995-1001
21. Yasunaga S., Kimura A., Hamaguchi K., Rønningen K.S., and Sasazuki T. Different contribution of HLA-DR and -DQ genes in susceptibility and resistance to insulin-dependent diabetes mellitus (IDDM). Tissue Antigens 47 (1996) 37-48
22. Awata T., Kuzuya T., Matsuda A., Iwamoto Y., and Kanazawa Y. Genetic analysis of HLA class II alleles and susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects. Diabetologia 35 (1992) 419-424