Discontinuation of quetiapine from an NIMH-funded trial due to serious adverse events

American Journal of Psychiatry

Volumn 166, Issue 8, 2009, Pages 937-938

  Jeste, Dilip V ^a   Jin, Hua ^a   Golshan, Shahrokh ^a   Mudaliar, Sunder ^a   Glorioso, Danielle ^a   Fellows, Ian ^a   Kraemer, Helena ^a   Arndt, Stephan ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARIPIPRAZOLE; ATYPICAL ANTIPSYCHOTIC AGENT; OLANZAPINE; QUETIAPINE; RISPERIDONE; DIBENZOTHIAZEPINE DERIVATIVE; NEUROLEPTIC AGENT;

ADULT; AGED; BIPOLAR DISORDER; CARDIOVASCULAR DISEASE; CEREBROVASCULAR DISEASE; CLINICAL TRIAL; COMORBIDITY; DEATH; DEMENTIA; DEPRESSION; DRUG SAFETY; DRUG WITHDRAWAL; FOOD AND DRUG ADMINISTRATION; HOSPITALIZATION; HUMAN; INFECTION; LETTER; MAJOR CLINICAL STUDY; MENTAL DISEASE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PNEUMONIA; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; PSYCHOSIS; RISK ASSESSMENT; SCHIZOPHRENIA; SEIZURE; SIDE EFFECT; SUICIDE ATTEMPT; TREATMENT OUTCOME; FINANCIAL MANAGEMENT; MAJOR DEPRESSION; NATIONAL HEALTH ORGANIZATION; PSYCHOLOGICAL ASPECT; RANDOMIZED CONTROLLED TRIAL; REGRESSION ANALYSIS; STATISTICS; UNITED STATES;

ANTIPSYCHOTIC AGENTS; DEPRESSIVE DISORDER, MAJOR; DIBENZOTHIAZEPINES; HUMANS; NATIONAL INSTITUTE OF MENTAL HEALTH (U.S.); RANDOMIZED CONTROLLED TRIALS AS TOPIC; REGRESSION ANALYSIS; RESEARCH SUPPORT AS TOPIC; UNITED STATES;

EID: 68149175328     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2009.09040501     Document Type: Letter

References (3)

1. University of California San Diego: Reporting Unanticipated Problems Involving Risk to Participants or Other (UPRs) to the IRB. http://irb.ucsd.edu/ Factsheet-UPR-120208.pdf
2. Jin H, Lanouette NM, Mudaliar S, Henry R, Folsom DP, Khandrika S, Glorioso DK, Jeste DV: Association of post-traumatic stress disorder with increased prevalence of metabolic syndrome. J Clin Psychopharmacol 2009; 29:210-215
3. Lavori PW, Rush AJ, Wisniewski SR, Alpert J, Fava M, Kupfer DJ, Nierenberg A, Quitkin FM, Sackeim HA, Thase ME, Trivedi M: Strengthening clinical effectiveness trials: equipoise-stratified randomization. Biol Psychiatry 2001; 50:792-801 (Pubitemid 33086767)