Rapid blood separation is superior to fluoride for preventing in vitro reductions in measured blood glucose concentration

Journal of Clinical Pathology

Volumn 62, Issue 8, 2009, Pages 752-753

  Shi, Run Zhang ^a   Seeley, E S ^a   Bowen, R ^a   Faix, J D ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORIDE; FLUORIDE SODIUM; GLUCOSE; HEPARIN DERIVATIVE; HEPARIN LITHIUM; OXALATE POTASSIUM; POTASSIUM DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; AUTOANALYSIS; BLOOD ANALYSIS; BLOOD SAMPLING; CENTRIFUGATION; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; PLASMA; PRIORITY JOURNAL; TUBE;

BLOOD GLUCOSE; BLOOD SPECIMEN COLLECTION; CENTRIFUGATION; GLYCOLYSIS; HEPARIN; HUMANS; LITHIUM; REPRODUCIBILITY OF RESULTS; SODIUM FLUORIDE; TIME FACTORS;

EID: 68149166768     PISSN: 00219746     EISSN: 14724146     Source Type: Journal    
DOI: 10.1136/jcp.2008.062547     Document Type: Article

References (5)

1. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2008;31(Suppl 1):S55-60.
2. Mikesh LM, Bruns DE. Stabilization of glucose in blood specimens: mechanism of delay in fluoride inhibition of glycolysis. Clin Chem 2008;54:930-932
3. Schwartz JG, Reichberg SB, Gambino RS. Glucose testing variability and the need for an expert oversight committee. CAP Today 2005;19:12, 14, 16.
4. Chan AY, Swaminathan R, Cockram CS. Effectiveness of sodium fluoride as a preservative of glucose in blood. Clin Chem 1989;35:315-317 (Pubitemid 19075618)
5. Waring WS, Evans LE, Kirkpatrick CT. Glycolysis inhibitors negatively bias blood glucose measurements: potential impact on the reported prevalence of diabetes mellitus. J Clin Pathol 2007;60:820-823