Mathematical biology education: Beyond calculus

Science

Volumn 325, Issue 5940, 2009, Pages 542-543

  Robeva, Raina ^a   Laubenbacher, Reinhard ^b  

^a SWEET BRIAR COLLEGE   (United States)

^b VIRGINIA BIOINFORMATICS INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGY; EDUCATION; NUMERICAL MODEL;

ALGORITHM; BIOINFORMATICS; BIOLOGY; BIOMEDICINE; CURRICULUM; EDUCATION; EVOLUTION; EXPERIMENT; GENE CONTROL; GENE REGULATORY NETWORK; GRADUATE; HEALTH CARE ORGANIZATION; KINETICS; LACTOSE OPERON; MATHEMATICAL MODEL; MATHEMATICS; MEDICAL RESEARCH; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; ORGANIZATION; PRIORITY JOURNAL; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; RNA STRUCTURE; SHORT SURVEY; SIGNAL TRANSDUCTION; STONE ANALYSIS;

BIOLOGY; COMPUTATIONAL BIOLOGY; CURRICULUM; GENE EXPRESSION REGULATION, BACTERIAL; LAC OPERON; MATHEMATICAL CONCEPTS; MATHEMATICS; MODELS, BIOLOGICAL; SYSTEMS BIOLOGY;

EID: 68149152274     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1176016     Document Type: Short Survey

References (24)

1. National Research Council, BIO2010: Transforming Undergraduate Education for Future Research Biologists (National Academies Press, Washington, DC, 2003).
2. N. Wingreen, D. Botstein, Nat. Rev. Mol. Cell Biol. 7, 829 (2006).
3. R. Robeva, Methods Enzymol. 454, 305 (2009).
4. Over the Fence: Mathematicians and Biologists Talk About Bridging the Curricular Divide, Mathematical Biosciences Institute workshop, Columbus, OH, 1 and 2 June 2007.
5. Computational and Mathematical Biology, Mathematical Association of America, Professional Enhancement Programs, 2003, 2004, 2005, 2006, and 2007.
6. Expanding Biomedical Research Opportunities at the Undergraduate Level, in Recovery Act Limited Competition: NIH Challenge Grants in Health and Science Research (RC1) (National Institutes of Health Program Solicitation 12-DK-102, Challenge Grant Applications, 2009); http://grants.nih.gov/grants/ funding/challengeaward/Omnibus.pdf.
7. Interdisciplinary Training for Undergraduates in Biological and Mathematical Sciences, (National Science Foundation Program Solicitation, NSF 08-510, 2008); www.nsf.gov/pubs/2008/nsf08510/nsf08510.htm.
8. Undergraduate Conference at the Interface between Mathematics and Biology, National Institute for Mathematical and Biological Synthesis (NimBioS), Knoxville, TN, 23 and 24 October 2009.
9. Undergraduate Research Conference in Quantitative Biology, Appalachian State University, Boone, NC, 2 and 3 November 2007 and 14 and 15 November 2008.
10. S. A. Kauffman, J. Theor. Biol. 22, 437 (1969).
11. A. Samal, S. Jain, BMC Syst. Biol. 2, 21 (2008).
12. R. Zhang et al., Proc. Natl. Acad. Sci. U.S.A. 105, 16308 (2008).
13. L. Pachter, B. Sturmfels, Proc. Natl. Acad. Sci. U.S.A. 101, 16132 (2004).
14. M. Sitharam, M. Agbandje-Mckenna, J. Comput. Biol. 13, 1232 (2006).
15. A. Apostolico et al., Nucleic Acids Res. 37, e29 (2009).
16. C. Neuhauser, Calculus for Biology and Medicine (Prentice-Hall, Upper Saddle River, NJ, ed. 2, 2003).
17. F. Adler, Modeling the Dynamics of Life: Calculus and Probability for Life Scientists (Thompson, Belmont, CA, ed. 2, 2005).
18. "MATH 127-Mathematics for Computational Biology" (University of California, Berkeley, CA, 2007); http://math.berkeley.edu/~bernd/math127.html.
19. "MATH, 295-Algebraic Statistics for Computational Biology" (Duke University, Durham, NC, 2005); www. math.duke.edu/graduate/courses/fall05/ math295.html.
20. R. Robeva et al., National Science Foundation DUE award 0737467, 2008; www.nsf.gov:80/awardsearch/ showAward.do?AwardNumber=0737467.
21. Biology Through Numbers Howard Hughes Medical Institute Award, 2006; www.hhmi.org/research/ professors/neuhauser.html.
22. E. M. Ozbudak, M. Thattai, H. N. Lim, B. I. Shraiman, A. van Oudenaarden, Nature 427, 737 (2004).
23. R. Laubenbacher, B. Sturmfels, Am. Math. Month. arXiv:0712.4248v2, in press.
24. The authors thank R. Davies from Sweet Briar College for her review of the biological content. Support by the NSF under the Division of Undergraduate Education; NSF Course, Curriculum, and Laboratory Improvement (CCLI) award 0737467 is also gratefully acknowledged.