Structure-analgesic activity relationship studies on the C18- and C19-diterpenoid alkaloids

Chemical and Pharmaceutical Bulletin

Volumn 57, Issue 8, 2009, Pages 801-807

  Wang, Jian Li ^a   Shen, Xiang Li ^a   Chen, Qiao Hong ^a   Qi, Gong ^b   Wang, Wei ^b   Wang, Feng Peng ^a  

^a SICHUAN UNIVERSITY   (China)

^b Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

Analgesic activity; Crassicauline A; Diterpenoid alkaloid; Lappaconitine; Yunaconitine

Indexed keywords

14 ACETYLBIKHACONINE; 8 DEACETOXY 8 ISOPENTOXYCRASSICAULINE A; 8 DEACETOXYL 8 BENZOYLOXYCRASSICAULINE A; 8 O DEACETYL 8 O ETHYLCRASSICAULINE A; 8 O ETHYLYUNACOTININE; 8,14 DIBENZOYLBIKHACONINE; ACETIC ACID; ALKALOID DERIVATIVE; AMINE; AROMATIC CARBOXYLIC ACID; BENZOYL PEROXIDE; C 18 DITERPENOID ALKALOID DERIVATIVE; C 19 DITERPENOID ALKALOID DERIVATIVE; CRASSICAULINE A; CRASSICAULINE A LACTAM; DITERPENOID; ESTER; ETHER; LAPPACONITINE; N DEETHYL N ACETYLLAPPACONITINE; N DEETHYL N,8,9 TRIACETYLLAPPACONITINE; N DEETHYL-5'' BROMOLAPPACONITINE IMINE; N DEETHYLCRASSICAULINE A; N DEETHYLCRASSICAULINE A IMINE; N DEETHYLLAPPACONITINE; N DEETHYLLAPPACONITINE IMINE; UNCLASSIFIED DRUG; YUNACONITINE;

ACONITUM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; ERUCTATION; FEMALE; MOUSE; NONHUMAN; PLANT ROOT; SALIVARY GLAND DISEASE; SHIVERING; STRUCTURE ACTIVITY RELATION;

ACETIC ACID; ACONITUM; ALKALOIDS; ANALGESICS; ANIMALS; DITERPENES; DRUG EVALUATION, PRECLINICAL; FEMALE; MICE; MICE, INBRED STRAINS; MODELS, ANIMAL; MOLECULAR CONFORMATION; PAIN; PAIN MEASUREMENT; PLANT ROOTS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 68149139669     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.57.801     Document Type: Article

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